New aromatase inhibitors. Synthesis and biological activity of aryl- substituted pyrrolizine and indolizine derivatives

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 5, 2000, Pages 945-955

  Sonnet, Pascal ^a   Dallemagne, Patrick ^a   Guillon, Jean ^a   Enguehard, Cécile ^a   Stiebing, Silvia ^a   Tanguy, Julien ^a   Bureau, Ronan ^a   Rault, Sylvain ^a   Auvray, Pierrïck ^b   Moslemi, Safa ^b   Sourdaine, Pascal ^b   Séralini, Gilles Eric ^b  

^a Laboratoire de Pharmacochimie   (France)

^b Lab Biochim Biol Molec E   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE INHIBITOR; INDOLIZINE DERIVATIVE; MR 20492; MR 20494; PYRROLIZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME KINETICS; HORSE; HUMAN; IC 50; MICROSOME; NONHUMAN; PHARMACOPHORE;

AROMATASE INHIBITORS; ENZYME INHIBITORS; HUMANS; INDOLIZINES; MAGNETIC RESONANCE SPECTROSCOPY; MICROSOMES; PLACENTA; PYRROLES; SPECTROPHOTOMETRY, INFRARED;

EQUUS CABALLUS;

EID: 0034119301     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00024-9     Document Type: Article

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