Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 20, 2000, Pages 2383-2386

  Jorgensen, Anker Steen ^a   Jacobsen, Poul ^a   Christiansen, Lise Brown ^a   Bury, Paul S ^a   Kanstrup, Anders ^a   Thorpe, Susan M ^a   Narum, Lars ^a   Wassermann, Karsten ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; INDOLIZINE DERIVATIVE; LIGAND; PYRROLO[2,1,5 CD]INDOLIZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ESTROGEN ACTIVITY; FEMALE; IC 50; NONHUMAN; RABBIT; STRUCTURE ANALYSIS; UTERUS;

DRUG DESIGN; ESTRADIOL; HUMAN; INDOLIZINES; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PYRROLES; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034675705     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00474-1     Document Type: Article

References (26)