메뉴 건너뛰기




Volumn 1320, Issue 1, 2014, Pages 76-92

Effects of new mutations on fitness: Insights from models and data

Author keywords

Distribution of fitness effects; Experimental evolution; Mutation; Mutational landscape models; Population genomics

Indexed keywords

ADAPTATION; ARTICLE; DNA POLYMORPHISM; EMPIRICISM; EVOLUTION; FITNESS; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HUMAN; MUTATION; MUTATION RATE; NONHUMAN; POPULATION; PREDICTION; STRENGTH; WILD TYPE;

EID: 84904381004     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.12460     Document Type: Article
Times cited : (63)

References (78)
  • 1
    • 77955842436 scopus 로고    scopus 로고
    • Fisher's model and the genomics of adaptation: restricted pleiotropy, heterogeneous mutation, and parallel evolution
    • Chevin, L.-M., G. Martin & T. Lenormand . 2010. Fisher's model and the genomics of adaptation: restricted pleiotropy, heterogeneous mutation, and parallel evolution. Evolution 64: 3213-3231.
    • (2010) Evolution , vol.64 , pp. 3213-3231
    • Chevin, L.-M.1    Martin, G.2    Lenormand, T.3
  • 2
    • 77951716714 scopus 로고    scopus 로고
    • Adaptation, plasticity, and extinction in a changing environment: towards a predictive theory
    • Chevin, L.-M., R. Lande & G. M. Mace . 2010. Adaptation, plasticity, and extinction in a changing environment: towards a predictive theory. PLoS Biol. 8: e1000357.
    • (2010) PLoS Biol. , vol.8
    • Chevin, L.-M.1    Lande, R.2    Mace, G.M.3
  • 3
    • 79952128475 scopus 로고    scopus 로고
    • Climate change and evolutionary adaptation
    • Hoffmann, A.A. & C.M. Sgrò . 2011. Climate change and evolutionary adaptation. Nature 470: 479-485.
    • (2011) Nature , vol.470 , pp. 479-485
    • Hoffmann, A.A.1    Sgrò, C.M.2
  • 4
    • 0036209507 scopus 로고    scopus 로고
    • Resolving the paradox of sex and recombination
    • Otto, S.P. & T. Lenormand . 2002. Resolving the paradox of sex and recombination. Nat. Rev. Genet. 3: 252-261.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 252-261
    • Otto, S.P.1    Lenormand, T.2
  • 5
    • 75449111415 scopus 로고    scopus 로고
    • Understanding and using quantitative genetic variation
    • Hill, W.G. 2010. Understanding and using quantitative genetic variation. Philos. Trans. R. Soc. Lond. B Biol. Sci. 365: 73-85.
    • (2010) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.365 , pp. 73-85
    • Hill, W.G.1
  • 6
    • 0033921235 scopus 로고    scopus 로고
    • Estimation of spontaneous genome-wide mutation rate parameters: whither beneficial mutations?
    • Bataillon, T. 2000. Estimation of spontaneous genome-wide mutation rate parameters: whither beneficial mutations?. Heredity 84: 497-501.
    • (2000) Heredity , vol.84 , pp. 497-501
    • Bataillon, T.1
  • 7
    • 77951584625 scopus 로고    scopus 로고
    • The population genetics of beneficial mutations
    • Orr, H.A. 2010. The population genetics of beneficial mutations. Philos. Trans. R. Soc. Lond. B Biol. Sci. 365: 1195-1201.
    • (2010) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.365 , pp. 1195-1201
    • Orr, H.A.1
  • 8
    • 76249110585 scopus 로고    scopus 로고
    • Abundant genetic variation + strong selection = multivariate genetic constraints: a geometric view of adaptation
    • Walsh, B. & M.W. Blows . 2009. Abundant genetic variation + strong selection = multivariate genetic constraints: a geometric view of adaptation. Annu. Rev. Ecol. Evol. Syst. 40: 41-59.
    • (2009) Annu. Rev. Ecol. Evol. Syst. , vol.40 , pp. 41-59
    • Walsh, B.1    Blows, M.W.2
  • 9
    • 7344220961 scopus 로고    scopus 로고
    • Risk of population extinction from fixation of deleterious and reverse mutations
    • Lande, R. 1998. Risk of population extinction from fixation of deleterious and reverse mutations. Genetica 102: 21-27.
    • (1998) Genetica , vol.102 , pp. 21-27
    • Lande, R.1
  • 10
    • 34548418873 scopus 로고    scopus 로고
    • Testing the extreme value domain of attraction for distributions of beneficial fitness effects
    • Beisel, C.J., D.R. Rokyta, H.A. Wichman & P. Joyce . 2007. Testing the extreme value domain of attraction for distributions of beneficial fitness effects. Genetics 176: 2441-2449.
    • (2007) Genetics , vol.176 , pp. 2441-2449
    • Beisel, C.J.1    Rokyta, D.R.2    Wichman, H.A.3    Joyce, P.4
  • 11
    • 59449088633 scopus 로고    scopus 로고
    • A general extreme value theory model for the adaptation of DNA sequences under strong selection and weak mutation
    • Joyce, P., D.R. Rokyta, C.J. Beisel & H.A. Orr . 2008. A general extreme value theory model for the adaptation of DNA sequences under strong selection and weak mutation. Genetics 180: 1627-1643.
    • (2008) Genetics , vol.180 , pp. 1627-1643
    • Joyce, P.1    Rokyta, D.R.2    Beisel, C.J.3    Orr, H.A.4
  • 14
    • 33747080569 scopus 로고    scopus 로고
    • A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species
    • Martin, G. & T. Lenormand . 2006. A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species. Evolution 60: 893-907.
    • (2006) Evolution , vol.60 , pp. 893-907
    • Martin, G.1    Lenormand, T.2
  • 15
    • 67849092403 scopus 로고    scopus 로고
    • The evolution of epistasis and its links with genetic robustness, complexity and drift in a phenotypic model of adaptation
    • Gros, P.-A., H. Le Nagard & O. Tenaillon . 2009. The evolution of epistasis and its links with genetic robustness, complexity and drift in a phenotypic model of adaptation. Genetics 182: 277-293.
    • (2009) Genetics , vol.182 , pp. 277-293
    • Gros, P.-A.1    Le Nagard, H.2    Tenaillon, O.3
  • 16
    • 79958074210 scopus 로고    scopus 로고
    • Complexity, pleiotropy, and the fitness effect of mutations
    • Lourenço, J., N. Galtier & S. Glémin . 2011. Complexity, pleiotropy, and the fitness effect of mutations. Evolution 65: 1559-1571.
    • (2011) Evolution , vol.65 , pp. 1559-1571
    • Lourenço, J.1    Galtier, N.2    Glémin, S.3
  • 17
    • 55249107194 scopus 로고    scopus 로고
    • Quantifying organismal complexity using a population genetic approach
    • Tenaillon, O., O.K. Silander, J.-P. Uzan & L. Chao . 2007. Quantifying organismal complexity using a population genetic approach. PLoS One 2: e217.
    • (2007) PLoS One , vol.2
    • Tenaillon, O.1    Silander, O.K.2    Uzan, J.-P.3    Chao, L.4
  • 18
    • 34047099379 scopus 로고    scopus 로고
    • Distributions of epistasis in microbes fit predictions from a fitness landscape model
    • Martin, G., S.F. Elena & T. Lenormand . 2007. Distributions of epistasis in microbes fit predictions from a fitness landscape model. Nat. Genet. 39: 555-560.
    • (2007) Nat. Genet. , vol.39 , pp. 555-560
    • Martin, G.1    Elena, S.F.2    Lenormand, T.3
  • 19
    • 67651119869 scopus 로고    scopus 로고
    • Fitness and its role in evolutionary genetics
    • Orr, H.A. 2009. Fitness and its role in evolutionary genetics. Nat. Rev. Genet. 10: 531-539.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 531-539
    • Orr, H.A.1
  • 20
    • 3142707245 scopus 로고    scopus 로고
    • Estimates of the genomic mutation rate for detrimental alleles in Drosophila melanogaster
    • Charlesworth, B., H. Borthwick, C. Bartolomé & P. Pignatelli . 2004. Estimates of the genomic mutation rate for detrimental alleles in Drosophila melanogaster. Genetics 167: 815-826.
    • (2004) Genetics , vol.167 , pp. 815-826
    • Charlesworth, B.1    Borthwick, H.2    Bartolomé, C.3    Pignatelli, P.4
  • 21
    • 0036811121 scopus 로고    scopus 로고
    • Spontaneous mutational variation for body size in Caenorhabditis elegans
    • Azevedo, R.B., P.D. Keightley, C. Laurén-Määttä, et al. 2002. Spontaneous mutational variation for body size in Caenorhabditis elegans. Genetics 162: 755-765.
    • (2002) Genetics , vol.162 , pp. 755-765
    • Azevedo, R.B.1    Keightley, P.D.2    Laurén-Määttä, C.3
  • 22
    • 79251553136 scopus 로고    scopus 로고
    • Diminishing returns from beneficial mutations and pervasive epistasis shape the fitness landscape for rifampicin resistance in Pseudomonas aeruginosa
    • MacLean, R., G.G. Perron & A. Gardner . 2010. Diminishing returns from beneficial mutations and pervasive epistasis shape the fitness landscape for rifampicin resistance in Pseudomonas aeruginosa. Genetics 186: 1345-1354.
    • (2010) Genetics , vol.186 , pp. 1345-1354
    • MacLean, R.1    Perron, G.G.2    Gardner, A.3
  • 23
    • 0008983173 scopus 로고    scopus 로고
    • Distribution of fitness effects caused by random insertion mutations in Escherichia coli
    • Elena, S.F., L. Ekunwe, N. Hajela, et al. 1998. Distribution of fitness effects caused by random insertion mutations in Escherichia coli. Genetica 102/103: 349-358.
    • (1998) Genetica , vol.102-103 , pp. 349-358
    • Elena, S.F.1    Ekunwe, L.2    Hajela, N.3
  • 24
    • 77952697477 scopus 로고    scopus 로고
    • Experimental genomics of fitness in yeast
    • Bell, G. 2010. Experimental genomics of fitness in yeast. Proc. R. Soc. B. Biol. Sci. 277: 1459-1467.
    • (2010) Proc. R. Soc. B. Biol. Sci. , vol.277 , pp. 1459-1467
    • Bell, G.1
  • 25
    • 79954465250 scopus 로고    scopus 로고
    • On measuring selection in experimental evolution
    • Chevin, L.-M. 2011. On measuring selection in experimental evolution. Biol. Lett. 7: 210-213.
    • (2011) Biol. Lett. , vol.7 , pp. 210-213
    • Chevin, L.-M.1
  • 26
    • 0001641514 scopus 로고
    • Mutations of bacteria from virus sensitivity to virus resistance
    • Luria, S.E. & M. Delbrück . 1943. Mutations of bacteria from virus sensitivity to virus resistance. Genetics 28: 491.
    • (1943) Genetics , vol.28 , pp. 491
    • Luria, S.E.1    Delbrück, M.2
  • 27
    • 33645394597 scopus 로고    scopus 로고
    • Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria
    • Kassen, R. & T. Bataillon . 2006. Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria. Nat. Genet. 38: 484-488.
    • (2006) Nat. Genet. , vol.38 , pp. 484-488
    • Kassen, R.1    Bataillon, T.2
  • 28
    • 0034006621 scopus 로고    scopus 로고
    • Determining mutation rates in bacterial populations
    • Rosche, W.A. & P.L. Foster . 2000. Determining mutation rates in bacterial populations. Methods 20: 4-17.
    • (2000) Methods , vol.20 , pp. 4-17
    • Rosche, W.A.1    Foster, P.L.2
  • 29
    • 62149084484 scopus 로고    scopus 로고
    • The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa
    • MacLean, R.C. & A. Buckling . 2009. The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa. PLoS Genet. 5: e1000406.
    • (2009) PLoS Genet. , vol.5
    • MacLean, R.C.1    Buckling, A.2
  • 30
    • 81255211330 scopus 로고    scopus 로고
    • Cost of adaptation and fitness effects of beneficial mutations in Pseudomonas fluorescens
    • Bataillon, T., T. Zhang & R. Kassen . 2011. Cost of adaptation and fitness effects of beneficial mutations in Pseudomonas fluorescens. Genetics 189: 939-949.
    • (2011) Genetics , vol.189 , pp. 939-949
    • Bataillon, T.1    Zhang, T.2    Kassen, R.3
  • 31
    • 79551470995 scopus 로고    scopus 로고
    • The distribution of fitness effects of new beneficial mutations in Pseudomonas fluorescens
    • McDonald, M.J., T.F. Cooper, H.J. Beaumont & P.B. Rainey . 2011. The distribution of fitness effects of new beneficial mutations in Pseudomonas fluorescens. Biol. Lett. 7: 98-100.
    • (2011) Biol. Lett. , vol.7 , pp. 98-100
    • McDonald, M.J.1    Cooper, T.F.2    Beaumont, H.J.3    Rainey, P.B.4
  • 33
    • 49849084622 scopus 로고    scopus 로고
    • The distribution of beneficial and fixed mutation fitness effects close to an optimum
    • Martin, G. & T. Lenormand . 2008. The distribution of beneficial and fixed mutation fitness effects close to an optimum. Genetics 179: 907-916.
    • (2008) Genetics , vol.179 , pp. 907-916
    • Martin, G.1    Lenormand, T.2
  • 34
    • 54349092997 scopus 로고    scopus 로고
    • Beneficial fitness effects are not exponential for two viruses
    • Rokyta, D.R., C.J. Beisel, P. Joyce, et al. 2008. Beneficial fitness effects are not exponential for two viruses. J. Mol. Evol. 67: 368-376.
    • (2008) J. Mol. Evol. , vol.67 , pp. 368-376
    • Rokyta, D.R.1    Beisel, C.J.2    Joyce, P.3
  • 35
    • 2942565781 scopus 로고    scopus 로고
    • The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus
    • Sanjuán, R., A. Moya & S.F. Elena . 2004. The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus. Proc. Natl. Acad. Sci. U. S. A. 101: 8396-8401.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 8396-8401
    • Sanjuán, R.1    Moya, A.2    Elena, S.F.3
  • 36
    • 78149293610 scopus 로고    scopus 로고
    • Mutational robustness of ribosomal protein genes
    • Lind, P.A., O.G. Berg & D.I. Andersson . 2010. Mutational robustness of ribosomal protein genes. Science 330: 825-827.
    • (2010) Science , vol.330 , pp. 825-827
    • Lind, P.A.1    Berg, O.G.2    Andersson, D.I.3
  • 37
  • 38
    • 36348963100 scopus 로고    scopus 로고
    • Distribution of fitness and virulence effects caused by single-nucleotide substitutions in tobacco etch virus
    • Carrasco, P., F. de la Iglesia & S.F. Elena . 2007. Distribution of fitness and virulence effects caused by single-nucleotide substitutions in tobacco etch virus. J. Virol. 81: 12979-12984.
    • (2007) J. Virol. , vol.81 , pp. 12979-12984
    • Carrasco, P.1    de la Iglesia, F.2    Elena, S.F.3
  • 39
    • 84881408157 scopus 로고    scopus 로고
    • Capturing the mutational landscape of the beta-lactamase TEM-1
    • Jacquier, H., A. Birgy, H. Le Nagard, et al. 2013. Capturing the mutational landscape of the beta-lactamase TEM-1. Proc. Natl. Acad. Sci. 110: 13067-13072.
    • (2013) Proc. Natl. Acad. Sci. , vol.110 , pp. 13067-13072
    • Jacquier, H.1    Birgy, A.2    Le Nagard, H.3
  • 40
    • 0000775877 scopus 로고
    • The measurement of gene mutation rate in Drosophila, its high variability, and its dependence upon temperature
    • Muller, H. 1928. The measurement of gene mutation rate in Drosophila, its high variability, and its dependence upon temperature. Genetics 13: 279.
    • (1928) Genetics , vol.13 , pp. 279
    • Muller, H.1
  • 41
    • 78651159254 scopus 로고
    • The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability
    • Mukai, T. 1964. The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability. Genetics 50: 1.
    • (1964) Genetics , vol.50 , pp. 1
    • Mukai, T.1
  • 42
    • 77951697965 scopus 로고    scopus 로고
    • Spontaneous mutation accumulation studies in evolutionary genetics
    • Halligan, D.L. & P.D. Keightley . 2009. Spontaneous mutation accumulation studies in evolutionary genetics. Annu. Rev. Ecol. Evol. Syst. 40: 151-172.
    • (2009) Annu. Rev. Ecol. Evol. Syst. , vol.40 , pp. 151-172
    • Halligan, D.L.1    Keightley, P.D.2
  • 43
    • 1942453396 scopus 로고    scopus 로고
    • Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegans
    • Estes, S., P.C. Phillips, D.R. Denver, et al. 2004. Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegans. Genetics 166: 1269-1279.
    • (2004) Genetics , vol.166 , pp. 1269-1279
    • Estes, S.1    Phillips, P.C.2    Denver, D.R.3
  • 44
    • 0037172667 scopus 로고    scopus 로고
    • Fitness effects of fixed beneficial mutations in microbial populations
    • Rozen, D.E., J. De Visser & P.J. Gerrish . 2002. Fitness effects of fixed beneficial mutations in microbial populations. Curr. Biol. 12: 1040-1045.
    • (2002) Curr. Biol. , vol.12 , pp. 1040-1045
    • Rozen, D.E.1    De Visser, J.2    Gerrish, P.J.3
  • 45
    • 84862840054 scopus 로고    scopus 로고
    • Cost of antibiotic resistance and the geometry of adaptation
    • Sousa, A., S. Magalhães & I. Gordo . 2012. Cost of antibiotic resistance and the geometry of adaptation. Mol. Biol. Evol. 29: 1417-1428.
    • (2012) Mol. Biol. Evol. , vol.29 , pp. 1417-1428
    • Sousa, A.1    Magalhães, S.2    Gordo, I.3
  • 46
    • 33645076253 scopus 로고    scopus 로고
    • An equivalence principle for the incorporation of favorable mutations in asexual populations
    • Hegreness, M., N. Shoresh, D. Hartl & R. Kishony . 2006. An equivalence principle for the incorporation of favorable mutations in asexual populations. Science 311: 1615-1617.
    • (2006) Science , vol.311 , pp. 1615-1617
    • Hegreness, M.1    Shoresh, N.2    Hartl, D.3    Kishony, R.4
  • 47
    • 84890874862 scopus 로고    scopus 로고
    • Rates of fitness decline and rebound suggest pervasive epistasis
    • Perfeito, L., A. Sousa, T. Bataillon & I. Gordo . 2014. Rates of fitness decline and rebound suggest pervasive epistasis. Evolution 68: 150-162.
    • (2014) Evolution , vol.68 , pp. 150-162
    • Perfeito, L.1    Sousa, A.2    Bataillon, T.3    Gordo, I.4
  • 48
    • 84891475093 scopus 로고    scopus 로고
    • An ABC method for estimating the rate and distribution of effects of beneficial mutations
    • de Sousa, J.A.M., P.R. Campos & I. Gordo . 2013. An ABC method for estimating the rate and distribution of effects of beneficial mutations. Genome Biol. Evol. 5: 794-806.
    • (2013) Genome Biol. Evol. , vol.5 , pp. 794-806
    • de Sousa, J.A.M.1    Campos, P.R.2    Gordo, I.3
  • 50
    • 77951615674 scopus 로고    scopus 로고
    • Genetic hitchhiking versus background selection: the controversy and its implications
    • Stephan, W. 2010. Genetic hitchhiking versus background selection: the controversy and its implications. Philos. Trans. R. Soc. Lond. B Biol. Sci. 365: 1245-1253.
    • (2010) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.365 , pp. 1245-1253
    • Stephan, W.1
  • 51
    • 84869453241 scopus 로고    scopus 로고
    • Adaptive evolution: evaluating empirical support for theoretical predictions
    • Olson-Manning, C.F., M.R. Wagner & T. Mitchell-Olds . 2012. Adaptive evolution: evaluating empirical support for theoretical predictions. Nat. Rev. Genet. 13: 867-877.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 867-877
    • Olson-Manning, C.F.1    Wagner, M.R.2    Mitchell-Olds, T.3
  • 52
    • 84866690688 scopus 로고    scopus 로고
    • Revisiting an old riddle: what determines genetic diversity levels within species?
    • Leffler, E.M., K. Bullaughey, D.R. Matute, et al. 2012. Revisiting an old riddle: what determines genetic diversity levels within species? PLoS Biol. 10: e1001388.
    • (2012) PLoS Biol. , vol.10
    • Leffler, E.M.1    Bullaughey, K.2    Matute, D.R.3
  • 53
    • 84876855375 scopus 로고    scopus 로고
    • Reference-free population genomics from next-generation transcriptome data and the vertebrate-invertebrate gap
    • Gayral, P., J. Melo-Ferreira, S. Glémin, et al. 2013. Reference-free population genomics from next-generation transcriptome data and the vertebrate-invertebrate gap. PLoS Genet. 9: e1003457.
    • (2013) PLoS Genet. , vol.9
    • Gayral, P.1    Melo-Ferreira, J.2    Glémin, S.3
  • 54
    • 60349093708 scopus 로고    scopus 로고
    • Effective population size and patterns of molecular evolution and variation
    • Charlesworth, B. 2009. Effective population size and patterns of molecular evolution and variation. Nat. Rev. Genet. 10: 195-205.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 195-205
    • Charlesworth, B.1
  • 55
    • 84878486976 scopus 로고    scopus 로고
    • Strong purifying selection at synonymous sites in D. melanogaster
    • Lawrie, D.S., P.W. Messer, R. Hershberg & D.A. Petrov . 2013. Strong purifying selection at synonymous sites in D. melanogaster. PLoS Genet. 9: e1003527.
    • (2013) PLoS Genet. , vol.9
    • Lawrie, D.S.1    Messer, P.W.2    Hershberg, R.3    Petrov, D.A.4
  • 56
    • 68949202924 scopus 로고    scopus 로고
    • Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change
    • Eyre-Walker, A. & P.D. Keightley . 2009. Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change. Mol. Biol. Evol. 26: 2097-2108.
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 2097-2108
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 57
    • 44949129000 scopus 로고    scopus 로고
    • Assessing the evolutionary impact of amino acid mutations in the human genome
    • Boyko, A.R., S.H. Williamson, A.R. Indap, et al. 2008. Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet. 4: e1000083.
    • (2008) PLoS Genet. , vol.4
    • Boyko, A.R.1    Williamson, S.H.2    Indap, A.R.3
  • 58
    • 84855266301 scopus 로고    scopus 로고
    • A population genetics-phylogenetics approach to inferring natural selection in coding sequences
    • Wilson, D.J., R.D. Hernandez, P. Andolfatto & M. Przeworski . 2011. A population genetics-phylogenetics approach to inferring natural selection in coding sequences. PLoS Genet. 7: e1002395.
    • (2011) PLoS Genet. , vol.7
    • Wilson, D.J.1    Hernandez, R.D.2    Andolfatto, P.3    Przeworski, M.4
  • 59
    • 84876350995 scopus 로고    scopus 로고
    • A comparison of models to infer the distribution of fitness effects of new mutations
    • Kousathanas, A. & P.D. Keightley . 2013. A comparison of models to infer the distribution of fitness effects of new mutations. Genetics 193: 1197-1208.
    • (2013) Genetics , vol.193 , pp. 1197-1208
    • Kousathanas, A.1    Keightley, P.D.2
  • 60
    • 70350164753 scopus 로고    scopus 로고
    • Measuring the rates of spontaneous mutation from deep and large-scale polymorphism data
    • Messer, P.W. 2009. Measuring the rates of spontaneous mutation from deep and large-scale polymorphism data. Genetics 182: 1219-1232.
    • (2009) Genetics , vol.182 , pp. 1219-1232
    • Messer, P.W.1
  • 61
    • 33745347447 scopus 로고    scopus 로고
    • The distribution of fitness effects of new deleterious amino acid mutations in humans
    • Eyre-Walker, A., M. Woolfit & T. Phelps . 2006. The distribution of fitness effects of new deleterious amino acid mutations in humans. Genetics 173: 891-900.
    • (2006) Genetics , vol.173 , pp. 891-900
    • Eyre-Walker, A.1    Woolfit, M.2    Phelps, T.3
  • 62
    • 84155170973 scopus 로고    scopus 로고
    • Joint analysis of demography and selection in population genetics: where do we stand and where could we go?
    • Li, J., H. Li, M. Jakobsson, et al. 2012. Joint analysis of demography and selection in population genetics: where do we stand and where could we go? Mol. Ecol. 21: 28-44.
    • (2012) Mol. Ecol. , vol.21 , pp. 28-44
    • Li, J.1    Li, H.2    Jakobsson, M.3
  • 63
    • 78649310938 scopus 로고    scopus 로고
    • Shifts in the intensity of purifying selection: an analysis of genome-wide polymorphism data from two closely related yeast species
    • Elyashiv, E., K. Bullaughey, S. Sattath, et al. 2010. Shifts in the intensity of purifying selection: an analysis of genome-wide polymorphism data from two closely related yeast species. Genome Res. 20: 1558-1573.
    • (2010) Genome Res. , vol.20 , pp. 1558-1573
    • Elyashiv, E.1    Bullaughey, K.2    Sattath, S.3
  • 64
    • 34547924819 scopus 로고    scopus 로고
    • Adaptive mutations in bacteria: high rate and small effects
    • Perfeito, Li., L. Fernandes, C. Mota & I. Gordo . 2007. Adaptive mutations in bacteria: high rate and small effects. Science 317: 813-815.
    • (2007) Science , vol.317 , pp. 813-815
    • Perfeito, L.1    Fernandes, L.2    Mota, C.3    Gordo, I.4
  • 65
    • 72949085559 scopus 로고    scopus 로고
    • The properties of adaptive walks in evolving populations of fungus
    • Schoustra, S.E., T. Bataillon, D.R. Gifford & R. Kassen . 2009. The properties of adaptive walks in evolving populations of fungus. PLoS Biol. 7: e1000250.
    • (2009) PLoS Biol. , vol.7
    • Schoustra, S.E.1    Bataillon, T.2    Gifford, D.R.3    Kassen, R.4
  • 66
    • 80054906747 scopus 로고    scopus 로고
    • The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans
    • Gifford, D.R., S.E. Schoustra & R. Kassen . 2011. The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans. Evolution 65: 3070-3078.
    • (2011) Evolution , vol.65 , pp. 3070-3078
    • Gifford, D.R.1    Schoustra, S.E.2    Kassen, R.3
  • 67
    • 29244453214 scopus 로고    scopus 로고
    • The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation
    • Orr, H.A. 2006. The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation. J. Theor. Biol. 238: 279-285.
    • (2006) J. Theor. Biol. , vol.238 , pp. 279-285
    • Orr, H.A.1
  • 68
    • 83455176994 scopus 로고    scopus 로고
    • A method for inferring the rate of occurrence and fitness effects of advantageous mutations
    • Schneider, A., B. Charlesworth, A. Eyre-Walker & P.D. Keightley . 2011. A method for inferring the rate of occurrence and fitness effects of advantageous mutations. Genetics 189: 1427-1437.
    • (2011) Genetics , vol.189 , pp. 1427-1437
    • Schneider, A.1    Charlesworth, B.2    Eyre-Walker, A.3    Keightley, P.D.4
  • 69
    • 0033677913 scopus 로고    scopus 로고
    • Compensating for our load of mutations: freezing the meltdown of small populations
    • Poon, A. & S.P. Otto . 2000. Compensating for our load of mutations: freezing the meltdown of small populations. Evolution 54: 1467-1479.
    • (2000) Evolution , vol.54 , pp. 1467-1479
    • Poon, A.1    Otto, S.P.2
  • 70
    • 84877155601 scopus 로고    scopus 로고
    • The probability of evolutionary rescue: towards a quantitative comparison between theory and evolution experiments
    • Martin, G., R. Aguilée, J. Ramsayer, et al. 2013. The probability of evolutionary rescue: towards a quantitative comparison between theory and evolution experiments. Philos. Trans. R. Soc. Lond. B Biol. Sci. 368: 20120088.
    • (2013) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.368 , pp. 20120088
    • Martin, G.1    Aguilée, R.2    Ramsayer, J.3
  • 71
    • 40849134461 scopus 로고    scopus 로고
    • Population genetics of polymorphism and divergence under fluctuating selection
    • Huerta-Sanchez, E., R. Durrett & C. D. Bustamante . 2008. Population genetics of polymorphism and divergence under fluctuating selection. Genetics 178: 325-337.
    • (2008) Genetics , vol.178 , pp. 325-337
    • Huerta-Sanchez, E.1    Durrett, R.2    Bustamante, C.D.3
  • 72
    • 73649127602 scopus 로고    scopus 로고
    • The fitness effects of random mutations in single-stranded DNA and RNA bacteriophages
    • Domingo-Calap, P., J.M. Cuevas & R. Sanjuán . 2009. The fitness effects of random mutations in single-stranded DNA and RNA bacteriophages. PLoS Genet. 5: e1000742.
    • (2009) PLoS Genet. , vol.5
    • Domingo-Calap, P.1    Cuevas, J.M.2    Sanjuán, R.3
  • 73
    • 77955475761 scopus 로고    scopus 로고
    • Distribution of fitness effects caused by single-nucleotide substitutions in bacteriophage f1
    • Peris, J.B., P. Davis, J.M. Cuevas, et al. 2010. Distribution of fitness effects caused by single-nucleotide substitutions in bacteriophage f1. Genetics 185: 603-609.
    • (2010) Genetics , vol.185 , pp. 603-609
    • Peris, J.B.1    Davis, P.2    Cuevas, J.M.3
  • 74
    • 0035970061 scopus 로고    scopus 로고
    • Fitness effects of advantageous mutations in evolving Escherichia coli populations
    • Imhof, M. & C. Schlötterer . 2001. Fitness effects of advantageous mutations in evolving Escherichia coli populations. Proc. Natl. Acad. Sci. 98: 1113-1117.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 1113-1117
    • Imhof, M.1    Schlötterer, C.2
  • 75
    • 33645112661 scopus 로고    scopus 로고
    • Mutations of intermediate effect are responsible for adaptation in evolving Pseudomonas fluorescens populations
    • Barrett, R.D., R.C. MacLean & G. Bell . 2006. Mutations of intermediate effect are responsible for adaptation in evolving Pseudomonas fluorescens populations. Biol. Lett. 2: 236-238.
    • (2006) Biol. Lett. , vol.2 , pp. 236-238
    • Barrett, R.D.1    MacLean, R.C.2    Bell, G.3
  • 76
    • 84863183635 scopus 로고    scopus 로고
    • Extensive X-linked adaptive evolution in central chimpanzees
    • Hvilsom, C., Y. Qian, T. Bataillon, et al. 2012. Extensive X-linked adaptive evolution in central chimpanzees. Proc. Natl. Acad. Sci. 109: 2054-2059.
    • (2012) Proc. Natl. Acad. Sci. , vol.109 , pp. 2054-2059
    • Hvilsom, C.1    Qian, Y.2    Bataillon, T.3
  • 77
    • 77954969511 scopus 로고    scopus 로고
    • Genome wide analyses reveal little evidence for adaptive evolution in many plant species
    • Gossmann, T.I., B.-H. Song, A.J. Windsor, et al. 2010. Genome wide analyses reveal little evidence for adaptive evolution in many plant species. Mol. Biol. Evol. 27: 1822-1832.
    • (2010) Mol. Biol. Evol. , vol.27 , pp. 1822-1832
    • Gossmann, T.I.1    Song, B.-H.2    Windsor, A.J.3
  • 78
    • 33644764039 scopus 로고    scopus 로고
    • Estimating selection on nonsynonymous mutations
    • Loewe, L., B. Charlesworth, C. Bartolomé & V. Nöel . 2006. Estimating selection on nonsynonymous mutations. Genetics 172: 1079-1092.
    • (2006) Genetics , vol.172 , pp. 1079-1092
    • Loewe, L.1    Charlesworth, B.2    Bartolomé, C.3    Nöel, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.