메뉴 건너뛰기




Volumn 65, Issue 6, 2011, Pages 1559-1571

Complexity, pleiotropy, and the fitness effect of mutations

Author keywords

Drift load; Genetic drift; Models; Molecular evolution; Natural selection

Indexed keywords

COMPLEXITY; EVOLUTIONARY BIOLOGY; FITNESS; GENE FLOW; GENETIC DRIFT; MOLECULAR ANALYSIS; MUTATION; NATURAL SELECTION; PLEIOTROPY;

EID: 79958074210     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/j.1558-5646.2011.01237.x     Document Type: Article
Times cited : (48)

References (47)
  • 2
    • 0035043379 scopus 로고    scopus 로고
    • The role of hybridization in evolution
    • Barton, N. H. 2001. The role of hybridization in evolution. Mol. Ecol. 10:551-568.
    • (2001) Mol. Ecol. , vol.10 , pp. 551-568
    • Barton, N.H.1
  • 3
    • 0033055004 scopus 로고    scopus 로고
    • Evolution by small steps and rugged landscapes in the RNA virus phi6
    • Burch, C. L., and L. Chao, 1999. Evolution by small steps and rugged landscapes in the RNA virus phi6. Genetics 151:921-927.
    • (1999) Genetics , vol.151 , pp. 921-927
    • Burch, C.L.1    Chao, L.2
  • 4
    • 0033543507 scopus 로고    scopus 로고
    • High frequency of cryptic deleterious mutations in Caenorhabditis elegans
    • Davies, E. K., A. D. Peters, and P. D. Keightley. 1999. High frequency of cryptic deleterious mutations in Caenorhabditis elegans. Science 285:1748-1751.
    • (1999) Science , vol.285 , pp. 1748-1751
    • Davies, E.K.1    Peters, A.D.2    Keightley, P.D.3
  • 5
    • 33748473348 scopus 로고    scopus 로고
    • The genomic rate of adaptive evolution
    • Eyre-Walker, A. 2006. The genomic rate of adaptive evolution. Trends Ecol. Evol. 21:569-575.
    • (2006) Trends Ecol. Evol. , vol.21 , pp. 569-575
    • Eyre-Walker, A.1
  • 6
    • 34447546660 scopus 로고    scopus 로고
    • The distribution of fitness effects of new mutations
    • Eyre-Walker, A., and P. D. Keightley. 2007. The distribution of fitness effects of new mutations. Nat. Rev. Genet. 8:610-618.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 610-618
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 7
    • 68949202924 scopus 로고    scopus 로고
    • Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change
    • Eyre-Walker, A., and P. D. Keightley. 2009. Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change. Mol. Biol. Evol. 26:2097-2108.
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 2097-2108
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 8
    • 33745347447 scopus 로고    scopus 로고
    • The distribution of fitness effects of new deleterious amino acid mutations in humans
    • Eyre-Walker, A., M. Woolfit, and T. Phelps. 2006. The distribution of fitness effects of new deleterious amino acid mutations in humans. Genetics 173:891-900.
    • (2006) Genetics , vol.173 , pp. 891-900
    • Eyre-Walker, A.1    Woolfit, M.2    Phelps, T.3
  • 10
    • 0027153175 scopus 로고
    • Substitution processes in molecular evolution. I. Uniform and clustered substitutions in a haploid model
    • Gillespie, J. H. 1993. Substitution processes in molecular evolution. I. Uniform and clustered substitutions in a haploid model. Genetics 134:971-981.
    • (1993) Genetics , vol.134 , pp. 971-981
    • Gillespie, J.H.1
  • 12
    • 34249035859 scopus 로고    scopus 로고
    • Evolutionary framework for protein sequence evolution and gene pleiotropy
    • Gu, X. 2007. Evolutionary framework for protein sequence evolution and gene pleiotropy. Genetics 175:1813-1822.
    • (2007) Genetics , vol.175 , pp. 1813-1822
    • Gu, X.1
  • 13
    • 0030574072 scopus 로고    scopus 로고
    • Compensatory nearly neutral mutations: selection without adaptation
    • Hartl, D., and C. H. Taubes. 1996. Compensatory nearly neutral mutations: selection without adaptation. J. Theor. Biol. 182:303-309.
    • (1996) J. Theor. Biol. , vol.182 , pp. 303-309
    • Hartl, D.1    Taubes, C.H.2
  • 14
    • 7344229253 scopus 로고    scopus 로고
    • Towards a theory of evolutionary adaptation
    • Hartl, D., and C. H. Taubes. 1998. Towards a theory of evolutionary adaptation. Genetica 102/103:525-533.
    • (1998) Genetica , vol.102-103 , pp. 525-533
    • Hartl, D.1    Taubes, C.H.2
  • 15
    • 57349194247 scopus 로고    scopus 로고
    • Pleiotropic scaling and QTL data
    • Hermisson, J., and A. P. McGregor. 2008. Pleiotropic scaling and QTL data. Nature 456:E3-E4.
    • (2008) Nature , vol.456
    • Hermisson, J.1    McGregor, A.P.2
  • 16
    • 0028072361 scopus 로고
    • The distribution of mutation effects on viability in Drosophila melanogaster
    • Keightley, P. 1994. The distribution of mutation effects on viability in Drosophila melanogaster. Genetics 138:1315-1322.
    • (1994) Genetics , vol.138 , pp. 1315-1322
    • Keightley, P.1
  • 17
    • 44449138056 scopus 로고    scopus 로고
    • Pleiotropic patterns of quantitative trait loci
    • Kenney-Hunt, J., B. Wang, Norgard E., and G. Fawcett. 2008. Pleiotropic patterns of quantitative trait loci. Genetics 178:2275-2288.
    • (2008) Genetics , vol.178 , pp. 2275-2288
    • Kenney-Hunt, J.1    Wang, B.2    Norgard, E.3    Fawcett, G.4
  • 18
    • 33644956987 scopus 로고
    • The mutation load in small populations
    • Kimura, M., T. Maruyama, and J. F. Crow. 1963. The mutation load in small populations. Genetics 48:1303-1312.
    • (1963) Genetics , vol.48 , pp. 1303-1312
    • Kimura, M.1    Maruyama, T.2    Crow, J.F.3
  • 19
    • 0018946312 scopus 로고
    • The genetic covariance between characters maintained by pleiotropic mutations
    • Lande, R. 1980. The genetic covariance between characters maintained by pleiotropic mutations. Genetics 94:203-215.
    • (1980) Genetics , vol.94 , pp. 203-215
    • Lande, R.1
  • 20
    • 33747080569 scopus 로고    scopus 로고
    • A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species
    • Martin, G., and T. Lenormand. 2006. A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species. Evolution 60:893-907.
    • (2006) Evolution , vol.60 , pp. 893-907
    • Martin, G.1    Lenormand, T.2
  • 21
    • 0031714655 scopus 로고    scopus 로고
    • The population genetics of adaptation: the distribution of factors fixed during adaptive evolution
    • Orr, H. A. 1998. The population genetics of adaptation: the distribution of factors fixed during adaptive evolution. Evolution 52:935-949.
    • (1998) Evolution , vol.52 , pp. 935-949
    • Orr, H.A.1
  • 22
    • 0343776158 scopus 로고    scopus 로고
    • The evolutionary genetics of adaptation: a simulation study
    • Orr, H. A. 1999. The evolutionary genetics of adaptation: a simulation study. Genet. Res. 74:207-214.
    • (1999) Genet. Res. , vol.74 , pp. 207-214
    • Orr, H.A.1
  • 23
    • 0034025692 scopus 로고    scopus 로고
    • Adaptation and the cost of complexity
    • Orr, H. A. 2000a. Adaptation and the cost of complexity. Evolution 54:13-20.
    • (2000) Evolution , vol.54 , pp. 13-20
    • Orr, H.A.1
  • 24
    • 0342657165 scopus 로고    scopus 로고
    • The rate of adaptation in asexuals
    • Orr, H. A. 2000b. The rate of adaptation in asexuals. Genetics 155:961-968.
    • (2000) Genetics , vol.155 , pp. 961-968
    • Orr, H.A.1
  • 25
    • 13144257707 scopus 로고    scopus 로고
    • The genetic theory of adaptation: a brief history
    • Orr, H. A. 2005a. The genetic theory of adaptation: a brief history. Nat. Rev. Genet. 6:119-127.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 119-127
    • Orr, H.A.1
  • 26
    • 16344391209 scopus 로고    scopus 로고
    • Theories of adaptation: what they do and don't say
    • Orr, H. A. 2005b. Theories of adaptation: what they do and don't say. Genetica 123:3-13.
    • (2005) Genetica , vol.123 , pp. 3-13
    • Orr, H.A.1
  • 27
    • 29244453214 scopus 로고    scopus 로고
    • The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation
    • Orr, H. A. 2006. The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation. J. Theor. Biol. 238:279-285.
    • (2006) J. Theor. Biol. , vol.238 , pp. 279-285
    • Orr, H.A.1
  • 28
    • 0030888873 scopus 로고    scopus 로고
    • Imperfect genes, Fisherian mutation and the evolution of sex
    • Peck, J. R., G. Barreau, and S. C. Heath. 1997. Imperfect genes, Fisherian mutation and the evolution of sex. Genetics 145:1171-1199.
    • (1997) Genetics , vol.145 , pp. 1171-1199
    • Peck, J.R.1    Barreau, G.2    Heath, S.C.3
  • 29
    • 0041836283 scopus 로고    scopus 로고
    • Estimating the distribution of fitness effects from DNA sequence data: implications for the molecular clock
    • Piganeau, G., and A. Eyre-Walker. 2003. Estimating the distribution of fitness effects from DNA sequence data: implications for the molecular clock. Proc. Natl. Acad. Sci. USA 100:10335-10340.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10335-10340
    • Piganeau, G.1    Eyre-Walker, A.2
  • 30
    • 0033677913 scopus 로고    scopus 로고
    • Compensating for our load of mutations: freezing the meltdown of small populations
    • Poon, A., and S. P. Otto. 2000. Compensating for our load of mutations: freezing the meltdown of small populations. Evolution 54:1467-1479.
    • (2000) Evolution , vol.54 , pp. 1467-1479
    • Poon, A.1    Otto, S.P.2
  • 32
    • 0036218367 scopus 로고    scopus 로고
    • A comprehensive model of mutations affecting fitness and inferences for Arabidopsis thaliana
    • Shaw, F. H., C. J. Geyer, and R. H. Shaw. 2002. A comprehensive model of mutations affecting fitness and inferences for Arabidopsis thaliana. Evolution 56:453-463.
    • (2002) Evolution , vol.56 , pp. 453-463
    • Shaw, F.H.1    Geyer, C.J.2    Shaw, R.H.3
  • 33
    • 34247349509 scopus 로고    scopus 로고
    • Understanding the evolutionary fate of finite populations: the dynamics of mutational effects
    • Silander, O. K., O. Tenaillon, and L. Chao. 2007. Understanding the evolutionary fate of finite populations: the dynamics of mutational effects. PLoS Biol. 5:e94.
    • (2007) PLoS Biol. , vol.5
    • Silander, O.K.1    Tenaillon, O.2    Chao, L.3
  • 34
    • 55249107194 scopus 로고    scopus 로고
    • Quantifying organismal complexity using a population genetic approach
    • Tenaillon, O., O. K. Silander, J. Uzan, and L. Chao. 2007. Quantifying organismal complexity using a population genetic approach. PLoS One 2:e217.
    • (2007) PLoS One , vol.2
    • Tenaillon, O.1    Silander, O.K.2    Uzan, J.3    Chao, L.4
  • 35
    • 0022233074 scopus 로고
    • Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits
    • Turelli, M. 1985. Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits. Genetics 111:165-195.
    • (1985) Genetics , vol.111 , pp. 165-195
    • Turelli, M.1
  • 36
    • 84993924998 scopus 로고
    • The influence of variation and developmental constraints on the rate of multivariate phenotypic evolution
    • Wagner, G. P. 1988. The influence of variation and developmental constraints on the rate of multivariate phenotypic evolution. J. Evol. Biol. 1:45-66.
    • (1988) J. Evol. Biol. , vol.1 , pp. 45-66
    • Wagner, G.P.1
  • 37
    • 0024523744 scopus 로고
    • Multivariate mutation-selection balance with constrained pleiotropic effects
    • Wagner, G. P. 1989. Multivariate mutation-selection balance with constrained pleiotropic effects. Genetics 122:223-234.
    • (1989) Genetics , vol.122 , pp. 223-234
    • Wagner, G.P.1
  • 40
    • 33746097735 scopus 로고    scopus 로고
    • Fisher's geometrical model of evolutionary adaptation-beyond spherical geometry
    • Waxman, D. 2006. Fisher's geometrical model of evolutionary adaptation-beyond spherical geometry. J. Theor. Biol. 241:887-895.
    • (2006) J. Theor. Biol. , vol.241 , pp. 887-895
    • Waxman, D.1
  • 41
    • 0032549157 scopus 로고    scopus 로고
    • Pleiotropy and the preservation of perfection
    • Waxman, D., and J. R. Peck. 1998. Pleiotropy and the preservation of perfection. Science 279:1210-1213.
    • (1998) Science , vol.279 , pp. 1210-1213
    • Waxman, D.1    Peck, J.R.2
  • 42
    • 26644472934 scopus 로고    scopus 로고
    • Fisher's microscope and Haldane's ellipse
    • Waxman, D., and J. J. Welch. 2005. Fisher's microscope and Haldane's ellipse. Am. Nat. 166:447-457.
    • (2005) Am. Nat. , vol.166 , pp. 447-457
    • Waxman, D.1    Welch, J.J.2
  • 43
    • 54349106869 scopus 로고    scopus 로고
    • Divergence and polymorphism under the nearly neutral theory of molecular evolution
    • Welch, J. J., A. Eyre-Walker, and D. Waxman. 2008. Divergence and polymorphism under the nearly neutral theory of molecular evolution. J. Mol. Evol. 67:418-426.
    • (2008) J. Mol. Evol. , vol.67 , pp. 418-426
    • Welch, J.J.1    Eyre-Walker, A.2    Waxman, D.3
  • 44
    • 0043286749 scopus 로고    scopus 로고
    • Modularity and the cost of complexity
    • Welch, J. J., and D. Waxman. 2003. Modularity and the cost of complexity. Evolution 57:1723-1734.
    • (2003) Evolution , vol.57 , pp. 1723-1734
    • Welch, J.J.1    Waxman, D.2
  • 45
    • 0043210647 scopus 로고    scopus 로고
    • Scaling of mutational effects in models for pleiotropy
    • Wingreen, N. S., J. Miller, and E. C. Cox. 2003. Scaling of mutational effects in models for pleiotropy. Genetics 164:1221-1228.
    • (2003) Genetics , vol.164 , pp. 1221-1228
    • Wingreen, N.S.1    Miller, J.2    Cox, E.C.3
  • 46
    • 0034765995 scopus 로고    scopus 로고
    • Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae
    • Wloch, D. M., K. Szafraniec, R. H. Borts, and R. Korona. 2001. Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae. Genetics 159:441-452.
    • (2001) Genetics , vol.159 , pp. 441-452
    • Wloch, D.M.1    Szafraniec, K.2    Borts, R.H.3    Korona, R.4
  • 47
    • 0043286740 scopus 로고    scopus 로고
    • Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation
    • Zhang, X., and W. G. Hill. 2003. Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation. Evolution 57:1761-1775.
    • (2003) Evolution , vol.57 , pp. 1761-1775
    • Zhang, X.1    Hill, W.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.