-
1
-
-
0024780087
-
Free radicals, reactive oxygen species and human disease: A critical evaluation with special reference to atherosclerosis
-
B. Halliwell: Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis. Br J Exp Pathol 70, 737-57 (1989)
-
(1989)
Br J Exp Pathol
, vol.70
, pp. 737-757
-
-
Halliwell, B.1
-
2
-
-
0029082812
-
Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism
-
D. M. Guidot, J. E. Repine, A. D. Kitlowski, S. C. Flores, S. K. Nelson, R. M. Wright and J. M. McCord: Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism. J Clin Invest 96, 1131-6 (1995)
-
(1995)
J Clin Invest
, vol.96
, pp. 1131-1136
-
-
Guidot, D.M.1
Repine, J.E.2
Kitlowski, A.D.3
Flores, S.C.4
Nelson, S.K.5
Wright, R.M.6
McCord, J.M.7
-
4
-
-
2342613645
-
Potential therapeutic effect of antioxidant therapy in shock and inflammation
-
S. Cuzzocrea, C. Thiemermann and D. Salvemini: Potential therapeutic effect of antioxidant therapy in shock and inflammation. Curr Med Chem 11, 1147-62 (2004)
-
(2004)
Curr Med Chem
, vol.11
, pp. 1147-1162
-
-
Cuzzocrea, S.1
Thiemermann, C.2
Salvemini, D.3
-
5
-
-
0024460992
-
Endogenous oxidative DNA damage, aging, and cancer
-
B. N. Ames: Endogenous oxidative DNA damage, aging, and cancer. Free Radic Res Commun, 7, 121-8 (1989)
-
(1989)
Free Radic Res Commun
, vol.7
, pp. 121-128
-
-
Ames, B.N.1
-
6
-
-
50849139232
-
Oxidative stress in psychiatric disorders: Evidence base and therapeutic implications
-
F. Ng, M. Berk, O. Dean and A. I. Bush: Oxidative stress in psychiatric disorders: evidence base and therapeutic implications. Int J Neuropsychopharmacol 11, 851-76 (2008)
-
(2008)
Int J Neuropsychopharmacol
, vol.11
, pp. 851-876
-
-
Ng, F.1
Berk, M.2
Dean, O.3
Bush, A.I.4
-
7
-
-
0034456207
-
Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems
-
K. J. Davies: Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems. IUBMB Life 50, 279-89 (2000)
-
(2000)
IUBMB Life
, vol.50
, pp. 279-289
-
-
Davies, K.J.1
-
8
-
-
0027937548
-
Oxidative stress: Free radical production in neural degeneration
-
M. E. Gotz, G. Kunig, P. Riederer and M. B. Youdim: Oxidative stress: free radical production in neural degeneration. Pharmacol Ther 63, 37-122 (1994)
-
(1994)
Pharmacol Ther
, vol.63
, pp. 37-122
-
-
Gotz, M.E.1
Kunig, G.2
Riederer, P.3
Youdim, M.B.4
-
9
-
-
0033910011
-
Significance of melatonin in antioxidative defense system: Reactions and products
-
D. X. Tan, L. C. Manchester, R. J. Reiter, W. B. Qi, M. Karbownik and J. R. Calvo: Significance of melatonin in antioxidative defense system: reactions and products. Biol Signals Recept 9, 137-59 (2000)
-
(2000)
Biol Signals Recept
, vol.9
, pp. 137-159
-
-
Tan, D.X.1
Manchester, L.C.2
Reiter, R.J.3
Qi, W.B.4
Karbownik, M.5
Calvo, J.R.6
-
10
-
-
0025915557
-
Melatonin: The chemical expression of darkness
-
R. J. Reiter: Melatonin: the chemical expression of darkness. Mol Cell Endocrinol 79, C153-8 (1991)
-
(1991)
Mol Cell Endocrinol
, vol.79
-
-
Reiter, R.J.1
-
11
-
-
0023196711
-
N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin levels in the Harderian glands of the female Syrian hamster: Changes during the light:Dark cycle and the effect of 6-parachlorophenylalanine administration
-
A. Menendez-Pelaez, K. A. Howes, A. Gonzalez-Brito and R. J. Reiter: N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin levels in the Harderian glands of the female Syrian hamster: changes during the light:dark cycle and the effect of 6-parachlorophenylalanine administration. Biochem Biophys Res Commun 145, 1231-8 (1987)
-
(1987)
Biochem Biophys Res Commun
, vol.145
, pp. 1231-1238
-
-
Menendez-Pelaez, A.1
Howes, K.A.2
Gonzalez-Brito, A.3
Reiter, R.J.4
-
12
-
-
0032829442
-
Identification of highly elevated levels of melatonin in bone marrow: Its origin and significance
-
D. X. Tan, L. C. Manchester, R. J. Reiter, W. B. Qi, M. Zhang, S. T. Weintraub, J. Cabrera, R. M. Sainz and J. C. Mayo: Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. Biochim Biophys Acta 1472, 206-14 (1999)
-
(1999)
Biochim Biophys Acta
, vol.1472
, pp. 206-214
-
-
Tan, D.X.1
Manchester, L.C.2
Reiter, R.J.3
Qi, W.B.4
Zhang, M.5
Weintraub, S.T.6
Cabrera, J.7
Sainz, R.M.8
Mayo, J.C.9
-
13
-
-
0033001521
-
The oxidant/antioxidant network: Role of melatonin
-
R. J. Reiter, D. X. Tan, J. Cabrera, D. D'Arpa, R. M. Sainz, J. C. Mayo and S. Ramos: The oxidant/antioxidant network: role of melatonin. Biol Signals Recept 8, 56-63 (1999)
-
(1999)
Biol Signals Recept
, vol.8
, pp. 56-63
-
-
Reiter, R.J.1
Tan, D.X.2
Cabrera, J.3
D'Arpa, D.4
Sainz, R.M.5
Mayo, J.C.6
Ramos, S.7
-
14
-
-
33749319658
-
Interactions of melatonin and its metabolites with the ABTS cation radical: Extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones
-
J. Rosen, N. N. Than, D. Koch, B. Poeggeler, H. Laatsch and R. Hardeland: Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones. J Pineal Res 41, 374-81 (2006)
-
(2006)
J Pineal Res
, vol.41
, pp. 374-381
-
-
Rosen, J.1
Than, N.N.2
Koch, D.3
Poeggeler, B.4
Laatsch, H.5
Hardeland, R.6
-
15
-
-
34147201601
-
AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice
-
K. Manda, M. Ueno and K. Anzai: AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. J Pineal Res 42, 386-93 (2007)
-
(2007)
J Pineal Res
, vol.42
, pp. 386-393
-
-
Manda, K.1
Ueno, M.2
Anzai, K.3
-
16
-
-
33845536018
-
One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
-
D. X. Tan, L. C. Manchester, M. P. Terron, L. J. Flores and R. J. Reiter: One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 42, 28-42 (2007)
-
(2007)
J Pineal Res
, vol.42
, pp. 28-42
-
-
Tan, D.X.1
Manchester, L.C.2
Terron, M.P.3
Flores, L.J.4
Reiter, R.J.5
-
17
-
-
23744513206
-
A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes
-
C. Tomas-Zapico and A. Coto-Montes: A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes. J Pineal Res 39, 99-104 (2005)
-
(2005)
J Pineal Res
, vol.39
, pp. 99-104
-
-
Tomas-Zapico, C.1
Coto-Montes, A.2
-
19
-
-
0036142587
-
Melatonin enters the cerebrospinal fluid through the pineal recess
-
H. Tricoire, A. Locatelli, P. Chemineau and B. Malpaux: Melatonin enters the cerebrospinal fluid through the pineal recess. Endocrinology 143, 84-90 (2002)
-
(2002)
Endocrinology
, vol.143
, pp. 84-90
-
-
Tricoire, H.1
Locatelli, A.2
Chemineau, P.3
Malpaux, B.4
-
20
-
-
0033305177
-
High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus
-
D. C. Skinner and B. Malpaux: High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology 140, 4399-405 (1999)
-
(1999)
Endocrinology
, vol.140
, pp. 4399-4405
-
-
Skinner, D.C.1
Malpaux, B.2
-
21
-
-
33749356167
-
Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration
-
R. T. Cheung, G. L. Tipoe, S. Tam, E. S. Ma, L. Y. Zou and P. S. Chan: Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration. J Pineal Res 41, 337-43 (2006)
-
(2006)
J Pineal Res
, vol.41
, pp. 337-343
-
-
Cheung, R.T.1
Tipoe, G.L.2
Tam, S.3
Ma, E.S.4
Zou, L.Y.5
Chan, P.S.6
-
22
-
-
0033925920
-
Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo
-
R. J. Reiter, D. X. Tan, W. Qi, L. C. Manchester, M. Karbownik and J. R. Calvo: Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo. Biol Signals Recept, 9, 160-71 (2000)
-
(2000)
Biol Signals Recept
, vol.9
, pp. 160-171
-
-
Reiter, R.J.1
Tan, D.X.2
Qi, W.3
Manchester, L.C.4
Karbownik, M.5
Calvo, J.R.6
-
23
-
-
0028924029
-
Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats
-
D. Melchiorri, R. J. Reiter, A. M. Attia, M. Hara, A. Burgos and G. Nistico: Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. Life Sci 56, 83-9 (1995)
-
(1995)
Life Sci
, vol.56
, pp. 83-89
-
-
Melchiorri, D.1
Reiter, R.J.2
Attia, A.M.3
Hara, M.4
Burgos, A.5
Nistico, G.6
-
24
-
-
0028821973
-
Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro
-
E. Sewerynek, D. Melchiorri, L. Chen and R. J. Reiter: Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro. Free Radic Biol Med 19, 903-9 (1995)
-
(1995)
Free Radic Biol Med
, vol.19
, pp. 903-909
-
-
Sewerynek, E.1
Melchiorri, D.2
Chen, L.3
Reiter, R.J.4
-
25
-
-
0027201993
-
The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo
-
D. X. Tan, B. Poeggeler, R. J. Reiter, L. D. Chen, S. Chen, L. C. Manchester and L. R. Barlow-Walden: The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. Cancer Lett 70, 65-71 (1993)
-
(1993)
Cancer Lett
, vol.70
, pp. 65-71
-
-
Tan, D.X.1
Poeggeler, B.2
Reiter, R.J.3
Chen, L.D.4
Chen, S.5
Manchester, L.C.6
Barlow-Walden, L.R.7
-
26
-
-
27644442295
-
Measurement of melatonin and its metabolites: Importance for the evaluation of their biological roles
-
G. R. Martinez, E. A. Almeida, C. F. Klitzke, J. Onuki, F. M. Prado, M. H. Medeiros and P. Di Mascio: Measurement of melatonin and its metabolites: importance for the evaluation of their biological roles. Endocrine 27, 111-8 (2005)
-
(2005)
Endocrine
, vol.27
, pp. 111-118
-
-
Martinez, G.R.1
Almeida, E.A.2
Klitzke, C.F.3
Onuki, J.4
Prado, F.M.5
Medeiros, M.H.6
Di Mascio, P.7
-
27
-
-
3142782935
-
Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage
-
R. J. Reiter, D. X. Tan, E. Gitto, R. M. Sainz, J. C. Mayo, J. Leon, L. C. Manchester, Vijayalaxmi, E. Kilic and U. Kilic: Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. Pol J Pharmacol 56, 159-70 (2004)
-
(2004)
Pol J Pharmacol
, vol.56
, pp. 159-170
-
-
Reiter, R.J.1
Tan, D.X.2
Gitto, E.3
Sainz, R.M.4
Mayo, J.C.5
Leon, J.6
Manchester, L.C.7
Vijayalaxmi8
Kilic, E.9
Kilic, U.10
-
28
-
-
0034763416
-
Individual and synergistic antioxidative actions of melatonin: Studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates
-
E. Gitto, D. X. Tan, R. J. Reiter, M. Karbownik, L. C. Manchester, S. Cuzzocrea, F. Fulia and I. Barberi: Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates. J Pharm Pharmacol 53, 1393-401 (2001)
-
(2001)
J Pharm Pharmacol
, vol.53
, pp. 1393-1401
-
-
Gitto, E.1
Tan, D.X.2
Reiter, R.J.3
Karbownik, M.4
Manchester, L.C.5
Cuzzocrea, S.6
Fulia, F.7
Barberi, I.8
-
29
-
-
0037025127
-
Melatonin prevents the formation of pyrrolized proteins in human plasma induced by hydrogen peroxide
-
F. Martinez-Cruz, J. M. Guerrero and C. Osuna: Melatonin prevents the formation of pyrrolized proteins in human plasma induced by hydrogen peroxide. Neurosci Lett 326, 147-50 (2002)
-
(2002)
Neurosci Lett
, vol.326
, pp. 147-150
-
-
Martinez-Cruz, F.1
Guerrero, J.M.2
Osuna, C.3
-
30
-
-
38149140283
-
Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage
-
R. J. Reiter, D. X. Tan, L. C. Manchester and H. Tamura: Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage. J Physiol Pharmacol 58, 5-22(2007)
-
(2007)
J Physiol Pharmacol
, vol.58
, pp. 5-22
-
-
Reiter, R.J.1
Tan, D.X.2
Manchester, L.C.3
Tamura, H.4
-
31
-
-
78049451374
-
Melatonin: A pleiotropic molecule regulating inflammation
-
F. Radogna, M. Diederich and L. Ghibelli: Melatonin: a pleiotropic molecule regulating inflammation. Biochem Pharmacol, 80, 1844-52 (2010)
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1844-1852
-
-
Radogna, F.1
Diederich, M.2
Ghibelli, L.3
-
32
-
-
0242333261
-
Melatonin protects against pro-oxidant enzymes and reduces lipid peroxidation in distinct membranes induced by the hydroxyl and ascorbyl radicals and by peroxynitrite
-
A.Teixeira, M. P. Morfim, C. A. de Cordova, C. C. Charao, V. R. de Lima and T. B. Creczynski-Pasa: Melatonin protects against pro-oxidant enzymes and reduces lipid peroxidation in distinct membranes induced by the hydroxyl and ascorbyl radicals and by peroxynitrite. J Pineal Res 35, 262-8 (2003)
-
(2003)
J Pineal Res
, vol.35
, pp. 262-268
-
-
Teixeira, A.1
Morfim, M.P.2
De Cordova, C.A.3
Charao, C.C.4
De Lima, V.R.5
Creczynski-Pasa, T.B.6
-
33
-
-
21144451785
-
Molecular evidence that melatonin is enzymatically oxidized in a different manner than tryptophan: Investigations with both indoleamine 2,3-dioxygenase and myeloperoxidase
-
G. Ferry, C. Ubeaud, P. H. Lambert, S. Bertin, F. Coge, P. Chomarat, P. Delagrange, B. Serkiz, J. P. Bouchet, R. J. Truscott and J. A. Boutin: Molecular evidence that melatonin is enzymatically oxidized in a different manner than tryptophan: investigations with both indoleamine 2,3-dioxygenase and myeloperoxidase. Biochem J 388, 205-15 (2005)
-
(2005)
Biochem J
, vol.388
, pp. 205-215
-
-
Ferry, G.1
Ubeaud, C.2
Lambert, P.H.3
Bertin, S.4
Coge, F.5
Chomarat, P.6
Delagrange, P.7
Serkiz, B.8
Bouchet, J.P.9
Truscott, R.J.10
Boutin, J.A.11
-
34
-
-
11844277100
-
The basic physiology and pathophysiology of melatonin
-
B. Claustrat, J. Brun and G. Chazot: The basic physiology and pathophysiology of melatonin. Sleep Med Rev 9, 11-24 (2005)
-
(2005)
Sleep Med Rev
, vol.9
, pp. 11-24
-
-
Claustrat, B.1
Brun, J.2
Chazot, G.3
-
35
-
-
0025758136
-
Pineal melatonin: Cell biology of its synthesis and of its physiological interactions
-
R. J. Reiter: Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr Rev 12, 151-80 (1991)
-
(1991)
Endocr Rev
, vol.12
, pp. 151-180
-
-
Reiter, R.J.1
-
36
-
-
33748042003
-
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin
-
J. Leon, G. Escames, M. I. Rodriguez, L. C. Lopez, V. Tapias, A. Entrena, E. Camacho, M. D. Carrion, M. A. Gallo, A. Espinosa, D. X. Tan, R. J. Reiter and D. Acuna-Castroviejo: Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin. J Neurochem 98, 2023-33 (2006)
-
(2006)
J Neurochem
, vol.98
, pp. 2023-2033
-
-
Leon, J.1
Escames, G.2
Rodriguez, M.I.3
Lopez, L.C.4
Tapias, V.5
Entrena, A.6
Camacho, E.7
Carrion, M.D.8
Gallo, M.A.9
Espinosa, A.10
Tan, D.X.11
Reiter, R.J.12
Acuna-Castroviejo, D.13
-
37
-
-
10744224028
-
Antioxidant properties of the melatonin metabolite N1-acetyl-5- methoxykynuramine (AMK): Scavenging of free radicals and prevention of protein destruction
-
A. R. Ressmeyer, J. C. Mayo, V. Zelosko, R. M. Sainz, D. X. Tan, B. Poeggeler, I. Antolin, B. K. Zsizsik, R. J. Reiter and R. Hardeland: Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox Rep 8, 205-13 (2003)
-
(2003)
Redox Rep
, vol.8
, pp. 205-213
-
-
Ressmeyer, A.R.1
Mayo, J.C.2
Zelosko, V.3
Sainz, R.M.4
Tan, D.X.5
Poeggeler, B.6
Antolin, I.7
Zsizsik, B.K.8
Reiter, R.J.9
Hardeland, R.10
-
38
-
-
34848844459
-
Reactions of the NO redox forms NO+, &z.Ast;NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine
-
R. Hardeland, C. Backhaus and A. Fadavi: Reactions of the NO redox forms NO+, &z.ast;NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine. J Pineal Res 43, 382-8 (2007)
-
(2007)
J Pineal Res
, vol.43
, pp. 382-388
-
-
Hardeland, R.1
Backhaus, C.2
Fadavi, A.3
-
39
-
-
22144498398
-
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages
-
J. C. Mayo, R. M. Sainz, D. X. Tan, R. Hardeland, J. Leon, C. Rodriguez and R. J. Reiter: Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J Neuroimmunol 165, 139-49 (2005)
-
(2005)
J Neuroimmunol
, vol.165
, pp. 139-149
-
-
Mayo, J.C.1
Sainz, R.M.2
Tan, D.X.3
Hardeland, R.4
Leon, J.5
Rodriguez, C.6
Reiter, R.J.7
-
40
-
-
77955607621
-
Melatonin: Pharmacological aspects and clinical trends
-
E. R. Rios, E. T. Venancio, N. F. Rocha, D. J. Woods, S. Vasconcelos, D. Macedo, F. C. Sousa and M. M. Fonteles: Melatonin: pharmacological aspects and clinical trends. Int J Neurosci, 120, 583-90 (2010)
-
(2010)
Int J Neurosci
, vol.120
, pp. 583-590
-
-
Rios, E.R.1
Venancio, E.T.2
Rocha, N.F.3
Woods, D.J.4
Vasconcelos, S.5
Macedo, D.6
Sousa, F.C.7
Fonteles, M.M.8
-
41
-
-
0031226491
-
Protective effect of melatonin in carrageenan-induced models of local inflammation: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity
-
S. Cuzzocrea, B. Zingarelli, E. Gilad, P. Hake, A. L. Salzman and C. Szabo: Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity. J Pineal Res 23, 106-16 (1997)
-
(1997)
J Pineal Res
, vol.23
, pp. 106-116
-
-
Cuzzocrea, S.1
Zingarelli, B.2
Gilad, E.3
Hake, P.4
Salzman, A.L.5
Szabo, C.6
-
42
-
-
0031853670
-
Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat
-
S. Cuzzocrea, B. Zingarelli, G. Costantino and A. P. Caputi: Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat. J Pineal Res 25, 24-33 (1998)
-
(1998)
J Pineal Res
, vol.25
, pp. 24-33
-
-
Cuzzocrea, S.1
Zingarelli, B.2
Costantino, G.3
Caputi, A.P.4
-
43
-
-
0033955015
-
Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion
-
S. Cuzzocrea, G. Costantino, E. Mazzon, A. Micali, A. De Sarro and A. P. Caputi: Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion. J Pineal Res 28, 52-63 (2000)
-
(2000)
J Pineal Res
, vol.28
, pp. 52-63
-
-
Cuzzocrea, S.1
Costantino, G.2
Mazzon, E.3
Micali, A.4
De Sarro, A.5
Caputi, A.P.6
-
44
-
-
0035191499
-
Melatonin reduces dinitrobenzene sulfonic acid-induced colitis
-
S. Cuzzocrea, E. Mazzon, I. Serraino, V. Lepore, M. L. Terranova, A. Ciccolo and A. P. Caputi: Melatonin reduces dinitrobenzene sulfonic acid-induced colitis. J Pineal Res 30, 1-12 (2001)
-
(2001)
J Pineal Res
, vol.30
, pp. 1-12
-
-
Cuzzocrea, S.1
Mazzon, E.2
Serraino, I.3
Lepore, V.4
Terranova, M.L.5
Ciccolo, A.6
Caputi, A.P.7
-
45
-
-
0034937764
-
Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation
-
L. Dugo, I. Serraino, F. Fulia, A. De Sarro, A. P. Caputi and S. Cuzzocrea: Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation. J Pineal Res 31, 76-84 (2001)
-
(2001)
J Pineal Res
, vol.31
, pp. 76-84
-
-
Dugo, L.1
Serraino, I.2
Fulia, F.3
De Sarro, A.4
Caputi, A.P.5
Cuzzocrea, S.6
-
46
-
-
0036483954
-
Pharmacological actions of melatonin in acute and chronic inflammation
-
S. Cuzzocrea, and R. J. Reiter: Pharmacological actions of melatonin in acute and chronic inflammation. Curr Top Med Chem 2, 153-65 (2002)
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 153-165
-
-
Cuzzocrea, S.1
Reiter, R.J.2
-
47
-
-
39749108884
-
Medical implications of melatonin: Receptor-mediated and receptor-independent actions
-
R. J. Reiter, D. X. Tan, L. C. Manchester, M. Pilar Terron, L. J. Flores and S. Koppisepi: Medical implications of melatonin: receptor-mediated and receptor-independent actions. Adv Med Sci 52, 11-28 (2007)
-
(2007)
Adv Med Sci
, vol.52
, pp. 11-28
-
-
Reiter, R.J.1
Tan, D.X.2
Manchester, L.C.3
Pilar Terron, M.4
Flores, L.J.5
Koppisepi, S.6
-
48
-
-
33749347001
-
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment
-
J. H. Weishaupt, C. Bartels, E. Polking, J. Dietrich, G. Rohde, B. Poeggeler, N. Mertens, S. Sperling, M. Bohn, G. Huther, A. Schneider, A. Bach, A. L. Siren, R. Hardeland, M. Bahr, K. A. Nave and H. Ehrenreich: Reduced oxidative damage in ALS by high-dose enteral melatonin treatment. J Pineal Res 41, 313-23 (2006)
-
(2006)
J Pineal Res
, vol.41
, pp. 313-323
-
-
Weishaupt, J.H.1
Bartels, C.2
Polking, E.3
Dietrich, J.4
Rohde, G.5
Poeggeler, B.6
Mertens, N.7
Sperling, S.8
Bohn, M.9
Huther, G.10
Schneider, A.11
Bach, A.12
Siren, A.L.13
Hardeland, R.14
Bahr, M.15
Nave, K.A.16
Ehrenreich, H.17
-
49
-
-
0030568587
-
In vitro inhibition of Ca2+/calmodulin-dependent kinase II activity by melatonin
-
G. Benitez-King, A. Rios, A. Martinez & F. Anton-Tay: In vitro inhibition of Ca2+/calmodulin-dependent kinase II activity by melatonin. Biochim Biophys Acta 1290, 191-6 (1996)
-
(1996)
Biochim Biophys Acta
, vol.1290
, pp. 191-196
-
-
Benitez-King, G.1
Rios, A.2
Martinez, A.3
Anton-Tay, F.4
-
51
-
-
0031297742
-
Melatonin receptors: Molecular biology of a new family of G protein-coupled receptors
-
S. M. Reppert: Melatonin receptors: molecular biology of a new family of G protein-coupled receptors. J Biol Rhythms 12, 528-31 (1997)
-
(1997)
J Biol Rhythms
, vol.12
, pp. 528-531
-
-
Reppert, S.M.1
-
52
-
-
0028104861
-
Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily
-
M. Becker-Andre, I. Wiesenberg, N. Schaeren-Wiemers, E. Andre, M. Missbach, J. H. Saurat and C. Carlberg: Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily. J Biol Chem 269, 28531-4 (1994)
-
(1994)
J Biol Chem
, vol.269
, pp. 28531-28534
-
-
Becker-Andre, M.1
Wiesenberg, I.2
Schaeren-Wiemers, N.3
Andre, E.4
Missbach, M.5
Saurat, J.H.6
Carlberg, C.7
-
53
-
-
80053385662
-
Melatonin-A pleiotropic, orchestrating regulator molecule
-
R. Hardeland, D. P. Cardinali, V. Srinivasan, D. W. Spence, G. M. Brown and S. R. Pandi-Perumal: Melatonin-A pleiotropic, orchestrating regulator molecule. Prog Neurobiol (2010)
-
(2010)
Prog Neurobiol
-
-
Hardeland, R.1
Cardinali, D.P.2
Srinivasan, V.3
Spence, D.W.4
Brown, G.M.5
Pandi-Perumal, S.R.6
-
54
-
-
3242753505
-
mRNA expression of nuclear receptor RZR/RORalpha, melatonin membrane receptor MT, and hydroxindole-O-methyltransferase in different populations of human immune cells
-
D. Pozo, S. Garcia-Maurino, J. M. Guerrero and J. R. Calvo: mRNA expression of nuclear receptor RZR/RORalpha, melatonin membrane receptor MT, and hydroxindole-O-methyltransferase in different populations of human immune cells. J Pineal Res 37, 48-54 (2004)
-
(2004)
J Pineal Res
, vol.37
, pp. 48-54
-
-
Pozo, D.1
Garcia-Maurino, S.2
Guerrero, J.M.3
Calvo, J.R.4
-
55
-
-
67349171366
-
Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism
-
F. Radogna, P. Sestili, C. Martinelli, M. Paolillo, L. Paternoster, M. C. Albertini, A. Accorsi, G. Gualandi and L. Ghibelli: Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism. Toxicol Appl Pharmacol 238, 170-7 (2009)
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, pp. 170-177
-
-
Radogna, F.1
Sestili, P.2
Martinelli, C.3
Paolillo, M.4
Paternoster, L.5
Albertini, M.C.6
Accorsi, A.7
Gualandi, G.8
Ghibelli, L.9
-
56
-
-
0034613342
-
Identification of the melatonin-binding site MT3 as the quinone reductase 2
-
O. Nosjean, M. Ferro, F. Coge, P. Beauverger, J. M. Henlin, F. Lefoulon, J. L. Fauchere, P. Delagrange, E. Canet and J. A. Boutin: Identification of the melatonin-binding site MT3 as the quinone reductase 2. J Biol Chem 275, 31311-7 (2000)
-
(2000)
J Biol Chem
, vol.275
, pp. 31311-31317
-
-
Nosjean, O.1
Ferro, M.2
Coge, F.3
Beauverger, P.4
Henlin, J.M.5
Lefoulon, F.6
Fauchere, J.L.7
Delagrange, P.8
Canet, E.9
Boutin, J.A.10
-
57
-
-
34848928810
-
Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor: Hypothesis and significance
-
D. X. Tan, L. C. Manchester, M. P. Terron, L. J. Flores, H. Tamura and R. J. Reiter: Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor: hypothesis and significance. J Pineal Res 43, 317-20 (2007)
-
(2007)
J Pineal Res
, vol.43
, pp. 317-320
-
-
Tan, D.X.1
Manchester, L.C.2
Terron, M.P.3
Flores, L.J.4
Tamura, H.5
Reiter, R.J.6
-
58
-
-
0037067791
-
Protective effect of melatonin in a chronic experimental model of Parkinson's disease
-
I. Antolin, J. C. Mayo, R. M. Sainz, L. del Brio Mde, F. Herrera, V. Martin and C. Rodriguez: Protective effect of melatonin in a chronic experimental model of Parkinson's disease. Brain Res 943, 163-73 (2002)
-
(2002)
Brain Res
, vol.943
, pp. 163-173
-
-
Antolin, I.1
Mayo, J.C.2
Sainz, R.M.3
Del Brio Mde, L.4
Herrera, F.5
Martin, V.6
Rodriguez, C.7
-
59
-
-
0036226252
-
Melatonin blocks rat hippocampal neuronal apoptosis induced by amyloid beta-peptide 25-35
-
Y. X. Shen, S. Y. Xu, W. Wei, X. L. Wang, H. Wang & X. Sun: Melatonin blocks rat hippocampal neuronal apoptosis induced by amyloid beta-peptide 25-35. J Pineal Res 32, 163-7 (2002)
-
(2002)
J Pineal Res
, vol.32
, pp. 163-167
-
-
Shen, Y.X.1
Xu, S.Y.2
Wei, W.3
Wang, X.L.4
Wang, H.5
Sun, X.6
-
60
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
M. T. Lin, and M. F. Beal: Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787-95 (2006)
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
61
-
-
44649145924
-
Particulate matter, oxidative stress and neurotoxicity
-
S. M. MohanKumar, A. Campbell, M. Block and B. Veronesi: Particulate matter, oxidative stress and neurotoxicity. Neurotoxicology 29, 479-88 (2008)
-
(2008)
Neurotoxicology
, vol.29
, pp. 479-488
-
-
MohanKumar, S.M.1
Campbell, A.2
Block, M.3
Veronesi, B.4
-
62
-
-
0034653993
-
Melatonin suppresses iron-induced neurodegeneration in rat brain
-
A. M. Lin, and L. T. Ho: Melatonin suppresses iron-induced neurodegeneration in rat brain. Free Radic Biol Med 28, 904-11 (2000)
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 904-911
-
-
Lin, A.M.1
Ho, L.T.2
-
63
-
-
1642483509
-
Neurodegenerative diseases and oxidative stress
-
J. Emerit, M. Edeas and F. Bricaire: Neurodegenerative diseases and oxidative stress. Biomed Pharmacother 58, 39-46 (2004)
-
(2004)
Biomed Pharmacother
, vol.58
, pp. 39-46
-
-
Emerit, J.1
Edeas, M.2
Bricaire, F.3
-
64
-
-
0035872474
-
Mechanisms by which metals promote events connected to neurodegenerative diseases
-
A. Campbell, M. A. Smith, L. M. Sayre, S. C. Bondy and G. Perry: Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Res Bull 55, 125-32 (2001)
-
(2001)
Brain Res Bull
, vol.55
, pp. 125-132
-
-
Campbell, A.1
Smith, M.A.2
Sayre, L.M.3
Bondy, S.C.4
Perry, G.5
-
65
-
-
3142713361
-
Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism responsible for antiapoptotic effects of melatonin
-
S. A. Andrabi, I. Sayeed, D. Siemen, G. Wolf and T. F. Horn: Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for antiapoptotic effects of melatonin. FASEB J 18, 869-71 (2004)
-
(2004)
FASEB J
, vol.18
, pp. 869-871
-
-
Andrabi, S.A.1
Sayeed, I.2
Siemen, D.3
Wolf, G.4
Horn, T.F.5
-
66
-
-
1842557679
-
Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator
-
E. Kilic, U. Kilic, B. Yulug, D. M. Hermann and R. J. Reiter: Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator. J Pineal Res 36, 171-6 (2004)
-
(2004)
J Pineal Res
, vol.36
, pp. 171-176
-
-
Kilic, E.1
Kilic, U.2
Yulug, B.3
Hermann, D.M.4
Reiter, R.J.5
-
67
-
-
12344285893
-
Melatonin mitigates mitochondrial malfunction
-
J. Leon, D. Acuna-Castroviejo, G. Escames, D. X. Tan and R. J. Reiter: Melatonin mitigates mitochondrial malfunction. J Pineal Res 38, 1-9 (2005)
-
(2005)
J Pineal Res
, vol.38
, pp. 1-9
-
-
Leon, J.1
Acuna-Castroviejo, D.2
Escames, G.3
Tan, D.X.4
Reiter, R.J.5
-
68
-
-
0038308447
-
Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: Implications for neuroprotection/neurodegeneration?
-
M. E. Gegg, B. Beltran, S. Salas-Pino, J. P. Bolanos, J. B. Clark, S. Moncada and S. J. Heales: Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration? J Neurochem 86, 228-37 (2003)
-
(2003)
J Neurochem
, vol.86
, pp. 228-237
-
-
Gegg, M.E.1
Beltran, B.2
Salas-Pino, S.3
Bolanos, J.P.4
Clark, J.B.5
Moncada, S.6
Heales, S.J.7
-
69
-
-
0027314268
-
Molecular profile of reactive astrocytes-implications for their role in neurologic disease
-
M. Eddleston and L. Mucke: Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 54, 15-36 (1993)
-
(1993)
Neuroscience
, vol.54
, pp. 15-36
-
-
Eddleston, M.1
Mucke, L.2
-
70
-
-
0037110424
-
The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis
-
A. Minagar, P. Shapshak, R. Fujimura, R. Ownby, M. Heyes and C. Eisdorfer: The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis. J Neurol Sci 202, 13-23 (2002)
-
(2002)
J Neurol Sci
, vol.202
, pp. 13-23
-
-
Minagar, A.1
Shapshak, P.2
Fujimura, R.3
Ownby, R.4
Heyes, M.5
Eisdorfer, C.6
-
71
-
-
0030881495
-
Nitric oxide in health and disease of the nervous system
-
H. Y. Yun, V. L. Dawson and T. M. Dawson: Nitric oxide in health and disease of the nervous system. Mol Psychiatry, 2, 300-10 (1997)
-
(1997)
Mol Psychiatry
, vol.2
, pp. 300-310
-
-
Yun, H.Y.1
Dawson, V.L.2
Dawson, T.M.3
-
72
-
-
36849059228
-
Signal transduction pathways involved in protective effects of melatonin in C6 glioma cells
-
E. Esposito, A. Iacono, C. Muia, C. Crisafulli, G. Mattace Raso, P. Bramanti, R. Meli and S. Cuzzocrea: Signal transduction pathways involved in protective effects of melatonin in C6 glioma cells. J Pineal Res 44, 78-87 (2008)
-
(2008)
J Pineal Res
, vol.44
, pp. 78-87
-
-
Esposito, E.1
Iacono, A.2
Muia, C.3
Crisafulli, C.4
Mattace Raso, G.5
Bramanti, P.6
Meli, R.7
Cuzzocrea, S.8
-
73
-
-
70449339417
-
The antiapoptotic activity of melatonin in neurodegenerative diseases
-
X. Wang: The antiapoptotic activity of melatonin in neurodegenerative diseases. CNS Neurosci Ther 15, 345-57 (2009)
-
(2009)
CNS Neurosci Ther
, vol.15
, pp. 345-357
-
-
Wang, X.1
-
75
-
-
34249072817
-
Effect of exogenous melatonin on sleep and motor dysfunction in Parkinson's disease. A randomized, double blind, placebo-controlled study
-
C. A. Medeiros, P. F. Carvalhedo de Bruin, L. A. Lopes, M. C. Magalhaes, M. de Lourdes Seabra and V. M. de Bruin: Effect of exogenous melatonin on sleep and motor dysfunction in Parkinson's disease. A randomized, double blind, placebo-controlled study. J Neurol 254, 459-64 (2007)
-
(2007)
J Neurol
, vol.254
, pp. 459-464
-
-
Medeiros, C.A.1
Carvalhedo De Bruin, P.F.2
Lopes, L.A.3
Magalhaes, M.C.4
De Lourdes Seabra, M.5
De Bruin, V.M.6
-
76
-
-
31344477300
-
Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease
-
R. Sharma, C. R. McMillan, C. C. Tenn and L. P. Niles: Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease. Brain Res 1068, 230-6 (2006)
-
(2006)
Brain Res
, vol.1068
, pp. 230-236
-
-
Sharma, R.1
McMillan, C.R.2
Tenn, C.C.3
Niles, L.P.4
-
77
-
-
79954477805
-
Melatonin ameliorates alzheimer-like pathological changes and spatial memory retention impairment induced by calyculin A
-
X. Yang, Y. Yang, Z. Fu, Y. Li, J. Feng, J. Luo, Q. Zhang, Q. Wang and Q. Tian: Melatonin ameliorates alzheimer-like pathological changes and spatial memory retention impairment induced by calyculin A. J Psychopharmacol (2010)
-
(2010)
J Psychopharmacol
-
-
Yang, X.1
Yang, Y.2
Fu, Z.3
Li, Y.4
Feng, J.5
Luo, J.6
Zhang, Q.7
Wang, Q.8
Tian, Q.9
-
78
-
-
67649905028
-
Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease
-
J. M. Olcese, C. Cao, T. Mori, M. B. Mamcarz, A. Maxwell, M. J. Runfeldt, L. Wang, C. Zhang, X. Lin, G. Zhang & G. W. Arendash: Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease. J Pineal Res 47, 82-96 (2009)
-
(2009)
J Pineal Res
, vol.47
, pp. 82-96
-
-
Olcese, J.M.1
Cao, C.2
Mori, T.3
Mamcarz, M.B.4
Maxwell, A.5
Runfeldt, M.J.6
Wang, L.7
Zhang, C.8
Lin, X.9
Zhang, G.10
Arendash, G.W.11
-
79
-
-
0036786208
-
Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): High tolerability of daily oral melatonin administration in ALS patients
-
S. Jacob, B. Poeggeler, J. H. Weishaupt, A. L. Siren, R. Hardeland, M. Bahr and H. Ehrenreich: Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients. J Pineal Res 33, 186-7 (2002)
-
(2002)
J Pineal Res
, vol.33
, pp. 186-187
-
-
Jacob, S.1
Poeggeler, B.2
Weishaupt, J.H.3
Siren, A.L.4
Hardeland, R.5
Bahr, M.6
Ehrenreich, H.7
-
80
-
-
70350460792
-
Neuroprotective effect of melatonin on experimental peripheral nerve injury: An electron microscopic and biochemical study
-
E. Daglioglu, M. Serdar Dike, K. Kilinc, D. Erdogan, G. Take, F. Ergungor, O. Okay and Z. Biyikli: Neuroprotective effect of melatonin on experimental peripheral nerve injury: an electron microscopic and biochemical study. Cen Eur Neurosurg 70, 109-14 (2009)
-
(2009)
Cen Eur Neurosurg
, vol.70
, pp. 109-114
-
-
Daglioglu, E.1
Serdar Dike, M.2
Kilinc, K.3
Erdogan, D.4
Take, G.5
Ergungor, F.6
Okay, O.7
Biyikli, Z.8
-
81
-
-
15444378210
-
Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin
-
T. Genovese, E. Mazzon, C. Muia, P. Bramanti, A. De Sarro and S. Cuzzocrea: Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin. J Pineal Res 38, 198-208 (2005)
-
(2005)
J Pineal Res
, vol.38
, pp. 198-208
-
-
Genovese, T.1
Mazzon, E.2
Muia, C.3
Bramanti, P.4
De Sarro, A.5
Cuzzocrea, S.6
-
82
-
-
0005130439
-
Clinical trials of controlled-release melatonin in children with sleep-wake cycle disorders
-
J. E. Jan, D. Hamilton, N. Seward, D. K. Fast, R. D. Freeman and M. Laudon: Clinical trials of controlled-release melatonin in children with sleep-wake cycle disorders. J Pineal Res 29, 34-9 (2000)
-
(2000)
J Pineal Res
, vol.29
, pp. 34-39
-
-
Jan, J.E.1
Hamilton, D.2
Seward, N.3
Fast, D.K.4
Freeman, R.D.5
Laudon, M.6
-
83
-
-
0033791313
-
Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment
-
M. L. Seabra, M. Bignotto, L. R. Pinto, Jr. and S. Tufik: Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment. J Pineal Res 29, 193-200 (2000)
-
(2000)
J Pineal Res
, vol.29
, pp. 193-200
-
-
Seabra, M.L.1
Bignotto, M.2
Pinto Jr., L.R.3
Tufik, S.4
-
84
-
-
34447303785
-
Alzheimer's disease and mild cognitive impairment
-
B. J. Kelley and R. C. Petersen: Alzheimer's disease and mild cognitive impairment. Neurol Clin 25, 577-609, (2007)
-
(2007)
Neurol Clin
, vol.25
, pp. 577-609
-
-
Kelley, B.J.1
Petersen, R.C.2
-
85
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
D. J. Selkoe: The molecular pathology of Alzheimer's disease. Neuron 6, 487-98 (1991)
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
86
-
-
0026823074
-
Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease
-
M. A. Pappolla, R. A. Omar, K. S. Kim and N. K. Robakis: Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. Am J Pathol 140, 621-8 (1992)
-
(1992)
Am J Pathol
, vol.140
, pp. 621-628
-
-
Pappolla, M.A.1
Omar, R.A.2
Kim, K.S.3
Robakis, N.K.4
-
87
-
-
0028129137
-
Evidence of an oxidative challenge in the Alzheimer's brain
-
L. Balazs and M. Leon: Evidence of an oxidative challenge in the Alzheimer's brain. Neurochem Res 19, 1131-7(1994)
-
(1994)
Neurochem Res
, vol.19
, pp. 1131-1137
-
-
Balazs, L.1
Leon, M.2
-
88
-
-
20444373701
-
Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets
-
R. Pamplona, E. Dalfo, V. Ayala, M. J. Bellmunt, J. Prat, I. Ferrer and M. Portero-Otin: Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets. J Biol Chem 280, 21522-30 (2005)
-
(2005)
J Biol Chem
, vol.280
, pp. 21522-21530
-
-
Pamplona, R.1
Dalfo, E.2
Ayala, V.3
Bellmunt, M.J.4
Prat, J.5
Ferrer, I.6
Portero-Otin, M.7
-
89
-
-
13844267510
-
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations
-
Q. Liu, M. A. Smith, J. Avila, J. DeBernardis, M. Kansal, A. Takeda, X. Zhu, A. Nunomura, K. Honda, P. I. Moreira, C. R. Oliveira, M. S. Santos, S. Shimohama, G. Aliev, J. de la Torre, H. A. Ghanbari, S. L. Siedlak, P. L. Harris, L. M. Sayre and G. Perry: Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med 38, 746-54 (2005)
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 746-754
-
-
Liu, Q.1
Smith, M.A.2
Avila, J.3
DeBernardis, J.4
Kansal, M.5
Takeda, A.6
Zhu, X.7
Nunomura, A.8
Honda, K.9
Moreira, P.I.10
Oliveira, C.R.11
Santos, M.S.12
Shimohama, S.13
Aliev, G.14
De La Torre, J.15
Ghanbari, H.A.16
Siedlak, S.L.17
Harris, P.L.18
Sayre, L.M.19
Perry, G.20
more..
-
90
-
-
0032521111
-
Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo
-
D. T. Weldon, S. D. Rogers, J. R. Ghilardi, M. P. Finke, J. P. Cleary, E. O'Hare, W. P. Esler, J. E. Maggio and P. W. Mantyh: Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo. J Neurosci 18, 2161-73 (1998)
-
(1998)
J Neurosci
, vol.18
, pp. 2161-2173
-
-
Weldon, D.T.1
Rogers, S.D.2
Ghilardi, J.R.3
Finke, M.P.4
Cleary, J.P.5
O'Hare, E.6
Esler, W.P.7
Maggio, J.E.8
Mantyh, P.W.9
-
91
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
D. J. Selkoe: Alzheimer's disease is a synaptic failure. Science 298, 789-91 (2002)
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
92
-
-
0343384322
-
Differential association of tau with subsets of microtubules containing posttranslationally-modified tubulin variants in neuroblastoma cells
-
L. Saragoni, P. Hernandez and R. B. Maccioni: Differential association of tau with subsets of microtubules containing posttranslationally-modified tubulin variants in neuroblastoma cells. Neurochem Res 25, 59-70 (2000)
-
(2000)
Neurochem Res
, vol.25
, pp. 59-70
-
-
Saragoni, L.1
Hernandez, P.2
Maccioni, R.B.3
-
93
-
-
0035224478
-
Neurofibrillary tangles and tau phosphorylation
-
J. P. Brion, B. H. Anderton, M. Authelet, R. Dayanandan, K. Leroy, S. Lovestone, J. N. Octave, L. Pradier, N. Touchet and G. Tremp: Neurofibrillary tangles and tau phosphorylation. Biochem Soc Symp 81-8 (2001)
-
(2001)
Biochem Soc Symp
, pp. 81-88
-
-
Brion, J.P.1
Anderton, B.H.2
Authelet, M.3
Dayanandan, R.4
Leroy, K.5
Lovestone, S.6
Octave, J.N.7
Pradier, L.8
Touchet, N.9
Tremp, G.10
-
94
-
-
77956197971
-
Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice
-
N. Dragicevic, M. Mamcarz, Y. Zhu, R. Buzzeo, J. Tan, G. W. Arendash and P. C. Bradshaw: Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice. J Alzheimers Dis 20, S535-50 (2010)
-
(2010)
J Alzheimers Dis
, vol.20
-
-
Dragicevic, N.1
Mamcarz, M.2
Zhu, Y.3
Buzzeo, R.4
Tan, J.5
Arendash, G.W.6
Bradshaw, P.C.7
-
95
-
-
77956224679
-
The Alzheimer's disease mitochondrial cascade hypothesis
-
R. H. Swerdlow, J. M. Burns and S. M. Khan: The Alzheimer's disease mitochondrial cascade hypothesis. J Alzheimers Dis 20, S265-79 (2010)
-
(2010)
J Alzheimers Dis
, vol.20
-
-
Swerdlow, R.H.1
Burns, J.M.2
Khan, S.M.3
-
96
-
-
0036174035
-
Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: Cross-sectional study
-
R. Ozcankaya, and N. Delibas: Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: cross-sectional study. Croat Med J 43, 28-32 (2002)
-
(2002)
Croat Med J
, vol.43
, pp. 28-32
-
-
Ozcankaya, R.1
Delibas, N.2
-
97
-
-
0030842459
-
Changes in endocrine circadian rhythms as markers of physiological and pathological brain aging
-
F. Magri, M. Locatelli, G. Balza, G. Molla, G. Cuzzoni, M. Fioravanti, S. B. Solerte and E. Ferrari: Changes in endocrine circadian rhythms as markers of physiological and pathological brain aging. Chronobiol Int 14, 385-96 (1997)
-
(1997)
Chronobiol Int
, vol.14
, pp. 385-396
-
-
Magri, F.1
Locatelli, M.2
Balza, G.3
Molla, G.4
Cuzzoni, G.5
Fioravanti, M.6
Solerte, S.B.7
Ferrari, E.8
-
98
-
-
0346732361
-
Molecular changes underlying reduced pineal melatonin levels in Alzheimer disease: Alterations in preclinical and clinical stages
-
Y. H. Wu, M. G. Feenstra, J. N. Zhou, R. Y. Liu, J. S. Torano, H. J. Van Kan, D. F. Fischer, R. Ravid and D. F. Swaab: Molecular changes underlying reduced pineal melatonin levels in Alzheimer disease: alterations in preclinical and clinical stages. J Clin Endocrinol Metab 88, 5898-906 (2003)
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5898-5906
-
-
Wu, Y.H.1
Feenstra, M.G.2
Zhou, J.N.3
Liu, R.Y.4
Torano, J.S.5
Van Kan, H.J.6
Fischer, D.F.7
Ravid, R.8
Swaab, D.F.9
-
99
-
-
0033647320
-
Pineal and pituitary-adrenocortical function in physiological aging and in senile dementia
-
E. Ferrari, A. Arcaini, R. Gornati, L. Pelanconi, L. Cravello, M. Fioravanti, S. B. Solerte and F. Magri: Pineal and pituitary-adrenocortical function in physiological aging and in senile dementia. Exp Gerontol 35, 1239-50 (2000)
-
(2000)
Exp Gerontol
, vol.35
, pp. 1239-1250
-
-
Ferrari, E.1
Arcaini, A.2
Gornati, R.3
Pelanconi, L.4
Cravello, L.5
Fioravanti, M.6
Solerte, S.B.7
Magri, F.8
-
100
-
-
0042090064
-
Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels
-
J. N. Zhou, R. Y. Liu, W. Kamphorst, M. A. Hofman and D. F. Swaab: Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels. J Pineal Res 35, 125-30 (2003)
-
(2003)
J Pineal Res
, vol.35
, pp. 125-130
-
-
Zhou, J.N.1
Liu, R.Y.2
Kamphorst, W.3
Hofman, M.A.4
Swaab, D.F.5
-
101
-
-
0032751648
-
Serum and cerebrospinal fluid concentrations of melatonin: A pilot study in healthy male volunteers
-
A. Rousseau, S. Petren, J. Plannthin, T. Eklundh and C. Nordin: Serum and cerebrospinal fluid concentrations of melatonin: a pilot study in healthy male volunteers. J Neural Transm 106, 883-8 (1999)
-
(1999)
J Neural Transm
, vol.106
, pp. 883-888
-
-
Rousseau, A.1
Petren, S.2
Plannthin, J.3
Eklundh, T.4
Nordin, C.5
-
102
-
-
0031053554
-
Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide
-
M. A. Pappolla, M. Sos, R. A. Omar, R. J. Bick, D. L. Hickson-Bick, R. J. Reiter, S. Efthimiopoulos and N. K. Robakis: Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. J Neurosci 17, 1683-90 (1997)
-
(1997)
J Neurosci
, vol.17
, pp. 1683-1690
-
-
Pappolla, M.A.1
Sos, M.2
Omar, R.A.3
Bick, R.J.4
Hickson-Bick, D.L.5
Reiter, R.J.6
Efthimiopoulos, S.7
Robakis, N.K.8
-
103
-
-
14644414141
-
Effect of melatonin on calyculin A-induced tau hyperphosphorylation
-
X. C. Li, Z. F. Wang, J. X. Zhang, Q. Wang and J. Z. Wang: Effect of melatonin on calyculin A-induced tau hyperphosphorylation. Eur J Pharmacol 510, 25-30 (2005)
-
(2005)
Eur J Pharmacol
, vol.510
, pp. 25-30
-
-
Li, X.C.1
Wang, Z.F.2
Zhang, J.X.3
Wang, Q.4
Wang, J.Z.5
-
104
-
-
31644432763
-
Beneficial effects of melatonin in experimental models of Alzheimer disease
-
Y. Cheng, Z. Feng, Q. Z. Zhang and J. T. Zhang: Beneficial effects of melatonin in experimental models of Alzheimer disease. Acta Pharmacol Sin 27, 129-39 (2006)
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 129-139
-
-
Cheng, Y.1
Feng, Z.2
Zhang, Q.Z.3
Zhang, J.T.4
-
105
-
-
0041765742
-
Beta-amyloid modulates tyrosine kinase B receptor expression in SHSY5Y neuroblastoma cells: Influence of the antioxidant melatonin
-
G. Olivieri, U. Otten, F. Meier, G. Baysang, B. Dimitriades-Schmutz, F. Muller-Spahn and E. Savaskan: Beta-amyloid modulates tyrosine kinase B receptor expression in SHSY5Y neuroblastoma cells: influence of the antioxidant melatonin. Neuroscience 120, 659-65 (2003)
-
(2003)
Neuroscience
, vol.120
, pp. 659-665
-
-
Olivieri, G.1
Otten, U.2
Meier, F.3
Baysang, G.4
Dimitriades-Schmutz, B.5
Muller-Spahn, F.6
Savaskan, E.7
-
106
-
-
0344131940
-
Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in rats
-
E. Crespo, M. Macias, D. Pozo, G. Escames, M. Martin, F. Vives, J. M. Guerrero and D. Acuna-Castroviejo: Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in rats. FASEB J 13, 1537-46 (1999)
-
(1999)
FASEB J
, vol.13
, pp. 1537-1546
-
-
Crespo, E.1
Macias, M.2
Pozo, D.3
Escames, G.4
Martin, M.5
Vives, F.6
Guerrero, J.M.7
Acuna-Castroviejo, D.8
-
107
-
-
0038661151
-
Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats
-
G. Escames, J. Leon, M. Macias, H. Khaldy and D. Acuna-Castroviejo: Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats. FASEB J 17, 932-4 (2003)
-
(2003)
FASEB J
, vol.17
, pp. 932-934
-
-
Escames, G.1
Leon, J.2
Macias, M.3
Khaldy, H.4
Acuna-Castroviejo, D.5
-
108
-
-
0033382517
-
Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative stress
-
J. J. Garcia, R. J. Reiter, J. Pie, G. G. Ortiz, J. Cabrera, R. M. Sainz and D. Acuna-Castroviejo: Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative stress. J Bioenerg Biomembr 31, 609-16 (1999)
-
(1999)
J Bioenerg Biomembr
, vol.31
, pp. 609-616
-
-
Garcia, J.J.1
Reiter, R.J.2
Pie, J.3
Ortiz, G.G.4
Cabrera, J.5
Sainz, R.M.6
Acuna-Castroviejo, D.7
-
109
-
-
0344492689
-
Monozygotic twins with Alzheimer's disease treated with melatonin: Case report
-
L. I. Brusco, M. Marquez and D. P. Cardinali: Monozygotic twins with Alzheimer's disease treated with melatonin: Case report. J Pineal Res 25, 260-3 (1998)
-
(1998)
J Pineal Res
, vol.25
, pp. 260-263
-
-
Brusco, L.I.1
Marquez, M.2
Cardinali, D.P.3
-
110
-
-
27744510015
-
Role of melatonin in neurodegenerative diseases
-
V. Srinivasan, S. R. Pandi-Perumal, G. J. Maestroni, A. I. Esquifino, R. Hardeland and D. P. Cardinali: Role of melatonin in neurodegenerative diseases. Neurotox Res 7, 293-318 (2005)
-
(2005)
Neurotox Res
, vol.7
, pp. 293-318
-
-
Srinivasan, V.1
Pandi-Perumal, S.R.2
Maestroni, G.J.3
Esquifino, A.I.4
Hardeland, R.5
Cardinali, D.P.6
-
111
-
-
0036227676
-
The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors
-
M. A. Pappolla, M. J. Simovich, T. Bryant-Thomas, Y. J. Chyan, B. Poeggeler, M. Dubocovich, R. Bick, G. Perry, F. Cruz-Sanchez and M. A. Smith: The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors. J Pineal Res 32, 135-42 (2002)
-
(2002)
J Pineal Res
, vol.32
, pp. 135-142
-
-
Pappolla, M.A.1
Simovich, M.J.2
Bryant-Thomas, T.3
Chyan, Y.J.4
Poeggeler, B.5
Dubocovich, M.6
Bick, R.7
Perry, G.8
Cruz-Sanchez, F.9
Smith, M.A.10
-
112
-
-
34247209678
-
Anti-inflammatory effect of melatonin on A beta vaccination in mice
-
E. P. Jesudason, B. Baben, B. S. Ashok, J. G. Masilamoni, R. Kirubagaran, W. C. Jebaraj and R. Jayakumar: Anti-inflammatory effect of melatonin on A beta vaccination in mice. Mol Cell Biochem 298, 69-81 (2007)
-
(2007)
Mol Cell Biochem
, vol.298
, pp. 69-81
-
-
Jesudason, E.P.1
Baben, B.2
Ashok, B.S.3
Masilamoni, J.G.4
Kirubagaran, R.5
Jebaraj, W.C.6
Jayakumar, R.7
-
113
-
-
0033968704
-
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease
-
M. A. Pappolla, Y. J. Chyan, B. Poeggeler, B. Frangione, G. Wilson, J. Ghiso and R. J. Reiter: An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease. J Neural Transm 107, 203-31(2000)
-
(2000)
J Neural Transm
, vol.107
, pp. 203-231
-
-
Pappolla, M.A.1
Chyan, Y.J.2
Poeggeler, B.3
Frangione, B.4
Wilson, G.5
Ghiso, J.6
Reiter, R.J.7
-
114
-
-
0032571381
-
Inhibition of Alzheimer beta-fibrillogenesis by melatonin
-
M. Pappolla, P. Bozner, C. Soto, H. Shao, N. K. Robakis, M. Zagorski, B. Frangione and J. Ghiso: Inhibition of Alzheimer beta-fibrillogenesis by melatonin. J Biol Chem 273, 7185-8 (1998)
-
(1998)
J Biol Chem
, vol.273
, pp. 7185-7188
-
-
Pappolla, M.1
Bozner, P.2
Soto, C.3
Shao, H.4
Robakis, N.K.5
Zagorski, M.6
Frangione, B.7
Ghiso, J.8
-
115
-
-
0031243561
-
Melatonin alters the metabolism of the beta-amyloid precursor protein in the neuroendocrine cell line PC12
-
W. Song, and D. K. Lahiri: Melatonin alters the metabolism of the beta-amyloid precursor protein in the neuroendocrine cell line PC12. J Mol Neurosci 9, 75-92 (1997)
-
(1997)
J Mol Neurosci
, vol.9
, pp. 75-92
-
-
Song, W.1
Lahiri, D.K.2
-
116
-
-
0035846613
-
Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide
-
B. Poeggeler, L. Miravalle, M. G. Zagorski, T. Wisniewski, Y. J. Chyan, Y. Zhang, H. Shao, T. Bryant-Thomas, R. Vidal, B. Frangione, J. Ghiso and M. A. Pappolla: Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide. Biochemistry 40, 14995-5001 (2001)
-
(2001)
Biochemistry
, vol.40
, pp. 14995-15001
-
-
Poeggeler, B.1
Miravalle, L.2
Zagorski, M.G.3
Wisniewski, T.4
Chyan, Y.J.5
Zhang, Y.6
Shao, H.7
Bryant-Thomas, T.8
Vidal, R.9
Frangione, B.10
Ghiso, J.11
Pappolla, M.A.12
-
117
-
-
0037565622
-
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
-
E. Matsubara, T. Bryant-Thomas, J. Pacheco Quinto, T. L. Henry, B. Poeggeler, D. Herbert, F. Cruz-Sanchez, Y. J. Chyan, M. A. Smith, G. Perry, M. Shoji, K. Abe, A. Leone, I. Grundke-Ikbal, G. L. Wilson, J. Ghiso, C. Williams, L. M. Refolo, M. A. Pappolla, D. G. Chain and E. Neria: Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem 85, 1101-8 (2003)
-
(2003)
J Neurochem
, vol.85
, pp. 1101-1108
-
-
Matsubara, E.1
Bryant-Thomas, T.2
Pacheco Quinto, J.3
Henry, T.L.4
Poeggeler, B.5
Herbert, D.6
Cruz-Sanchez, F.7
Chyan, Y.J.8
Smith, M.A.9
Perry, G.10
Shoji, M.11
Abe, K.12
Leone, A.13
Grundke-Ikbal, I.14
Wilson, G.L.15
Ghiso, J.16
Williams, C.17
Refolo, L.M.18
Pappolla, M.A.19
Chain, D.G.20
Neria, E.21
more..
-
118
-
-
14944341045
-
Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: Implications for clinical trials
-
J. Quinn, D. Kulhanek, J. Nowlin, R. Jones, D. Pratico, J. Rokach and R. Stackman: Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials. Brain Res 1037, 209-13 (2005)
-
(2005)
Brain Res
, vol.1037
, pp. 209-213
-
-
Quinn, J.1
Kulhanek, D.2
Nowlin, J.3
Jones, R.4
Pratico, D.5
Rokach, J.6
Stackman, R.7
-
119
-
-
28744450569
-
Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease
-
Z. Feng, C. Qin, Y. Chang and J. T. Zhang: Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease. Free Radic Biol Med 40, 101-9 (2006)
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 101-109
-
-
Feng, Z.1
Qin, C.2
Chang, Y.3
Zhang, J.T.4
-
120
-
-
49549092451
-
Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-beta1-42
-
J. Zhou, S. Zhang, X. Zhao and T. Wei: Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-beta1-42. J Pineal Res 45, 157-65 (2008)
-
(2008)
J Pineal Res
, vol.45
, pp. 157-165
-
-
Zhou, J.1
Zhang, S.2
Zhao, X.3
Wei, T.4
-
121
-
-
18744415485
-
Effects of melatonin on wortmannin-induced tau hyperphosphorylation
-
Y. Q. Deng, G. G. Xu, P. Duan, Q. Zhang and J. Z. Wang: Effects of melatonin on wortmannin-induced tau hyperphosphorylation. Acta Pharmacol Sin 26, 519-26 (2005)
-
(2005)
Acta Pharmacol Sin
, vol.26
, pp. 519-526
-
-
Deng, Y.Q.1
Xu, G.G.2
Duan, P.3
Zhang, Q.4
Wang, J.Z.5
-
122
-
-
4344568620
-
Melatonin alleviates behavioral deficits associated with apoptosis and cholinergic system dysfunction in the APP 695 transgenic mouse model of Alzheimer's disease
-
Z. Feng, Y. Chang, Y. Cheng, B. L. Zhang, Z. W. Qu, C. Qin and J. T. Zhang: Melatonin alleviates behavioral deficits associated with apoptosis and cholinergic system dysfunction in the APP 695 transgenic mouse model of Alzheimer's disease. J Pineal Res 37, 129-36 (2004)
-
(2004)
J Pineal Res
, vol.37
, pp. 129-136
-
-
Feng, Z.1
Chang, Y.2
Cheng, Y.3
Zhang, B.L.4
Qu, Z.W.5
Qin, C.6
Zhang, J.T.7
-
123
-
-
7444246751
-
Protective effect of melatonin on beta-amyloid-induced apoptosis in rat astroglioma C6 cells and its mechanism
-
Z. Feng, and J. T. Zhang: Protective effect of melatonin on beta-amyloid-induced apoptosis in rat astroglioma C6 cells and its mechanism. Free Radic Biol Med 37, 1790-801 (2004)
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1790-1801
-
-
Feng, Z.1
Zhang, J.T.2
-
124
-
-
4644342312
-
Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats
-
Z. Feng, Y. Cheng and J. T. Zhang: Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats. J Pineal Res 37, 198-206 (2004)
-
(2004)
J Pineal Res
, vol.37
, pp. 198-206
-
-
Feng, Z.1
Cheng, Y.2
Zhang, J.T.3
-
126
-
-
1342269759
-
Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. A review
-
R. M. Kostrzewa and J. Segura-Aguilar: Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. a review. Neurotox Res 5, 375-83 (2003)
-
(2003)
Neurotox Res
, vol.5
, pp. 375-383
-
-
Kostrzewa, R.M.1
Segura-Aguilar, J.2
-
127
-
-
33847777698
-
Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease
-
P. Brunner, N. Sozer-Topcular, R. Jockers, R. Ravid, D. Angeloni, F. Fraschini, A. Eckert, F. Muller-Spahn and E. Savaskan: Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease. Eur J Histochem 50, 311-6 (2006)
-
(2006)
Eur J Histochem
, vol.50
, pp. 311-316
-
-
Brunner, P.1
Sozer-Topcular, N.2
Jockers, R.3
Ravid, R.4
Angeloni, D.5
Fraschini, F.6
Eckert, A.7
Muller-Spahn, F.8
Savaskan, E.9
-
129
-
-
0041817939
-
Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and noncognitive functions in Alzheimer type dementia
-
K. Asayama, H. Yamadera, T. Ito, H. Suzuki, Y. Kudo and S. Endo: Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and noncognitive functions in Alzheimer type dementia. J Nippon Med Sch 70, 334-41(2003)
-
(2003)
J Nippon Med Sch
, vol.70
, pp. 334-341
-
-
Asayama, K.1
Yamadera, H.2
Ito, T.3
Suzuki, H.4
Kudo, Y.5
Endo, S.6
-
131
-
-
0034732614
-
Redox reactions of neurotransmitters possibly involved in the progression of Parkinson's Disease
-
W. Linert and G. N. Jameson: Redox reactions of neurotransmitters possibly involved in the progression of Parkinson's Disease. J Inorg Biochem 79, 319-26 (2000)
-
(2000)
J Inorg Biochem
, vol.79
, pp. 319-326
-
-
Linert, W.1
Jameson, G.N.2
-
132
-
-
0026520425
-
The nature of Parkinson's disease
-
D. B. Calne: The nature of Parkinson's disease. Neurochem Int 20, 1S-3S (1992)
-
(1992)
Neurochem Int
, vol.20
-
-
Calne, D.B.1
-
133
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
T. Kitada, S. Asakawa, N. Hattori, H. Matsumine, Y. Yamamura, S. Minoshima, M. Yokochi, Y. Mizuno and N. Shimizu: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-8 (1998)
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
134
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
R. Betarbet, T. B. Sherer, G. MacKenzie, M. Garcia-Osuna, A. V. Panov and J. T. Greenamyre: Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3, 1301-6 (2000)
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
135
-
-
0035696302
-
Mechanisms of parkinsonism: Session X summary and research needs
-
D. Di Monte and C. P. Lawler: Mechanisms of parkinsonism: session X summary and research needs. Neurotoxicology 22, 853-4 (2001)
-
(2001)
Neurotoxicology
, vol.22
, pp. 853-854
-
-
Di Monte, D.1
Lawler, C.P.2
-
136
-
-
0036715374
-
Potential neurotoxic "agents provocateurs" in Parkinson's disease
-
M. A. Collins and E. J. Neafsey: Potential neurotoxic "agents provocateurs" in Parkinson's disease. Neurotoxicol Teratol 24, 571-7 (2002)
-
(2002)
Neurotoxicol Teratol
, vol.24
, pp. 571-577
-
-
Collins, M.A.1
Neafsey, E.J.2
-
137
-
-
0026484388
-
The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
-
S. Fahn and G. Cohen: The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 32, 804-12 (1992)
-
(1992)
Ann Neurol
, vol.32
, pp. 804-812
-
-
Fahn, S.1
Cohen, G.2
-
138
-
-
0025242960
-
Oxidation reactions in Parkinson's disease
-
discussion 37-9
-
C. W. Olanow: Oxidation reactions in Parkinson's disease. Neurology 40, discussion 37-9 (1990)
-
(1990)
Neurology
, vol.40
-
-
Olanow, C.W.1
-
139
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
-
Z. I. Alam, A. Jenner, S. E. Daniel, A. J. Lees, N. Cairns, C. D. Marsden, P. Jenner and B. Halliwell: Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J Neurochem 69, 1196-203 (1997)
-
(1997)
J Neurochem
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
140
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
D. T. Dexter, C. J. Carter, F. R. Wells, F. Javoy-Agid, Y. Agid, A. Lees, P. Jenner and C. D. Marsden: Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J Neurochem 52, 381-9 (1989)
-
(1989)
J Neurochem
, vol.52
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
141
-
-
0022553605
-
Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
-
T. L. Perry and V. W. Yong: Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci Lett 67, 269-74 (1986)
-
(1986)
Neurosci Lett
, vol.67
, pp. 269-274
-
-
Perry, T.L.1
Yong, V.W.2
-
142
-
-
0034624017
-
The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity
-
J. Lotharius and K. L. O'Malley: The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity. J Biol Chem 275, 38581-8 (2000)
-
(2000)
J Biol Chem
, vol.275
, pp. 38581-38588
-
-
Lotharius, J.1
O'Malley, K.L.2
-
143
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
J. W. Langston, P. Ballard, J. W. Tetrud and I. Irwin: Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219, 979-80 (1983)
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
144
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1, 2,5,6-tetrahydropyridine
-
W. J. Nicklas, I. Vyas and R. E. Heikkila: Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci 36, 2503-8 (1985)
-
(1985)
Life Sci
, vol.36
, pp. 2503-2508
-
-
Nicklas, W.J.1
Vyas, I.2
Heikkila, R.E.3
-
145
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
-
Y. Zhang, V. L. Dawson and T. M. Dawson: Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol Dis 7, 240-50 (2000)
-
(2000)
Neurobiol Dis
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
147
-
-
0027535984
-
Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons
-
P. Hantraye, M. Varastet, M. Peschanski, D. Riche, P. Cesaro, J. C. Willer and M. Maziere: Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons. Neuroscience 53, 169-78 (1993)
-
(1993)
Neuroscience
, vol.53
, pp. 169-178
-
-
Hantraye, P.1
Varastet, M.2
Peschanski, M.3
Riche, D.4
Cesaro, P.5
Willer, J.C.6
Maziere, M.7
-
148
-
-
22044448363
-
Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro
-
L. J. Chen, Y. Q. Gao, X. J. Li, D. H. Shen and F. Y. Sun: Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro. J Pineal Res 39, 34-42 (2005)
-
(2005)
J Pineal Res
, vol.39
, pp. 34-42
-
-
Chen, L.J.1
Gao, Y.Q.2
Li, X.J.3
Shen, D.H.4
Sun, F.Y.5
-
149
-
-
11444259754
-
The neuronal cytoskeleton as a potential therapeutical target in neurodegenerative diseases and schizophrenia
-
G. Benitez-King, G. Ramirez-Rodriguez, L. Ortiz and I. Meza: The neuronal cytoskeleton as a potential therapeutical target in neurodegenerative diseases and schizophrenia. Curr Drug Targets CNS Neurol Disord 3, 515-33 (2004)
-
(2004)
Curr Drug Targets CNS Neurol Disord
, vol.3
, pp. 515-533
-
-
Benitez-King, G.1
Ramirez-Rodriguez, G.2
Ortiz, L.3
Meza, I.4
-
150
-
-
0035170284
-
Melatonin protects against 6-OHDA-induced neurotoxicity in rats: A role for mitochondrial complex I activity
-
F. Dabbeni-Sala, S. Di Santo, D. Franceschini, S. D. Skaper and P. Giusti: Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity. FASEB J 15, 164-170 (2001)
-
(2001)
FASEB J
, vol.15
, pp. 164-170
-
-
Dabbeni-Sala, F.1
Di Santo, S.2
Franceschini, D.3
Skaper, S.D.4
Giusti, P.5
-
151
-
-
0031827090
-
Inhibition of cell proliferation: A mechanism likely to mediate the prevention of neuronal cell death by melatonin
-
J. C. Mayo, R. M. Sainz, H. Uria, I. Antolin, M. M. Esteban and Rodriguez: Inhibition of cell proliferation: a mechanism likely to mediate the prevention of neuronal cell death by melatonin. J Pineal Res 25, 12-8 (1998)
-
(1998)
J Pineal Res
, vol.25
, pp. 12-18
-
-
Mayo, J.C.1
Sainz, R.M.2
Uria, H.3
Antolin, I.4
Esteban, M.M.5
Rodriguez6
-
152
-
-
16244416841
-
Mitochondrial complex I, II/III, and IV activities in familial and sporadic Parkinson's disease
-
H. A. Hanagasi, D. Ayribas, K. Baysal and M. Emre: Mitochondrial complex I, II/III, and IV activities in familial and sporadic Parkinson's disease. Int J Neurosci 115, 479-93 (2005)
-
(2005)
Int J Neurosci
, vol.115
, pp. 479-493
-
-
Hanagasi, H.A.1
Ayribas, D.2
Baysal, K.3
Emre, M.4
-
153
-
-
33644809553
-
Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease
-
D. Alvira, M. Tajes, E. Verdaguer, D. Acuna-Castroviejo, J. Folch, A. Camins and M. Pallas: Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease. J Pineal Res 40, 251-8 (2006)
-
(2006)
J Pineal Res
, vol.40
, pp. 251-258
-
-
Alvira, D.1
Tajes, M.2
Verdaguer, E.3
Acuna-Castroviejo, D.4
Folch, J.5
Camins, A.6
Pallas, M.7
-
154
-
-
25644456097
-
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
-
M. Kitazawa, S. Oddo, T. R. Yamasaki, K. N. Green and F. M. LaFerla: Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci 25, 8843-53 (2005)
-
(2005)
J Neurosci
, vol.25
, pp. 8843-8853
-
-
Kitazawa, M.1
Oddo, S.2
Yamasaki, T.R.3
Green, K.N.4
LaFerla, F.M.5
-
155
-
-
0345270390
-
Study of circadian melatonin secretion pattern at different stages of Parkinson's disease
-
R. Bordet, D. Devos, S. Brique, Y. Touitou, J. D. Guieu, C. Libersa and A. Destee: Study of circadian melatonin secretion pattern at different stages of Parkinson's disease. Clin Neuropharmacol 26, 65-72 (2003)
-
(2003)
Clin Neuropharmacol
, vol.26
, pp. 65-72
-
-
Bordet, R.1
Devos, D.2
Brique, S.3
Touitou, Y.4
Guieu, J.D.5
Libersa, C.6
Destee, A.7
-
156
-
-
0029866124
-
Melatonin-dopamine interaction in the striatal projection area of sensorimotor cortex in the rat
-
G. Escames, D. Acuna Castroviejo and F. Vives: Melatonin-dopamine interaction in the striatal projection area of sensorimotor cortex in the rat. Neuroreport 7, 597-600 (1996)
-
(1996)
Neuroreport
, vol.7
, pp. 597-600
-
-
Escames, G.1
Acuna Castroviejo, D.2
Vives, F.3
-
157
-
-
0035158194
-
Melatonin treatment for tardive dyskinesia: A double-blind, placebo-controlled, crossover study
-
E. Shamir, Y. Barak, I. Shalman, M. Laudon, N. Zisapel, R. Tarrasch, A. Elizur and R. Weizman: Melatonin treatment for tardive dyskinesia: a double-blind, placebo-controlled, crossover study. Arch Gen Psychiatry 58, 1049-52 (2001)
-
(2001)
Arch Gen Psychiatry
, vol.58
, pp. 1049-1052
-
-
Shamir, E.1
Barak, Y.2
Shalman, I.3
Laudon, M.4
Zisapel, N.5
Tarrasch, R.6
Elizur, A.7
Weizman, R.8
-
158
-
-
0031886418
-
The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: Assessment in a clinical trial of melatonin replacement
-
R. J. Hughes, R. L. Sack and A. J. Lewy: The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement. Sleep 21, 52-68 (1998)
-
(1998)
Sleep
, vol.21
, pp. 52-68
-
-
Hughes, R.J.1
Sack, R.L.2
Lewy, A.J.3
-
159
-
-
24344486006
-
Melatonin for sleep disturbances in Parkinson's disease
-
G. A. Dowling, J. Mastick, E. Colling, J. H. Carter, C. M. Singer and M. J. Aminoff: Melatonin for sleep disturbances in Parkinson's disease. Sleep Med 6, 459-66 (2005)
-
(2005)
Sleep Med
, vol.6
, pp. 459-466
-
-
Dowling, G.A.1
Mastick, J.2
Colling, E.3
Carter, J.H.4
Singer, C.M.5
Aminoff, M.J.6
-
160
-
-
0028352974
-
Chrono-neuroendocrinological aspects of physiological aging and senile dementia
-
D. Dori, G. Casale, S. B. Solerte, M. Fioravanti, G. Migliorati, G. Cuzzoni and E. Ferrari: Chrono-neuroendocrinological aspects of physiological aging and senile dementia. Chronobiologia 21, 121-6 (1994)
-
(1994)
Chronobiologia
, vol.21
, pp. 121-126
-
-
Dori, D.1
Casale, G.2
Solerte, S.B.3
Fioravanti, M.4
Migliorati, G.5
Cuzzoni, G.6
Ferrari, E.7
-
161
-
-
0035142213
-
Diminished melatonin secretion in the elderly caused by insufficient environmental illumination
-
K. Mishima, M. Okawa, T. Shimizu and Y. Hishikawa: Diminished melatonin secretion in the elderly caused by insufficient environmental illumination. J Clin Endocrinol Metab 86, 129-34 (2001)
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 129-134
-
-
Mishima, K.1
Okawa, M.2
Shimizu, T.3
Hishikawa, Y.4
-
162
-
-
78650031174
-
Huntington's disease: From molecular pathogenesis to clinical treatment
-
C. A. Ross, and S. J. Tabrizi: Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 10, 83-98 (2011)
-
(2011)
Lancet Neurol
, vol.10
, pp. 83-98
-
-
Ross, C.A.1
Tabrizi, S.J.2
-
163
-
-
33846225133
-
Huntington's disease
-
F. O. Walker: Huntington's disease. Lancet 369, 218-28 (2007)
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
164
-
-
0034571171
-
Huntington's disease: The challenge for cell biologists
-
A. J. Tobin and E. R. Signer: Huntington's disease: the challenge for cell biologists. Trends Cell Biol 10, 531-6 (2000)
-
(2000)
Trends Cell Biol
, vol.10
, pp. 531-536
-
-
Tobin, A.J.1
Signer, E.R.2
-
165
-
-
42249109228
-
Rapid eye movement sleep disturbances in Huntington disease
-
I. Arnulf, J. Nielsen, E. Lohmann, J. Schiefer, E. Wild, P. Jennum, E. Konofal, M. Walker, D. Oudiette, S. Tabrizi and A. Durr: Rapid eye movement sleep disturbances in Huntington disease. Arch Neurol 65, 482-8 (2008)
-
(2008)
Arch Neurol
, vol.65
, pp. 482-488
-
-
Arnulf, I.1
Nielsen, J.2
Lohmann, E.3
Schiefer, J.4
Wild, E.5
Jennum, P.6
Konofal, E.7
Walker, M.8
Oudiette, D.9
Tabrizi, S.10
Durr, A.11
-
166
-
-
49249089029
-
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
-
M. Bjorkqvist, E. J. Wild, J. Thiele, A. Silvestroni, R. Andre, N. Lahiri, E. Raibon, R. V. Lee, C. L. Benn, D. Soulet, A. Magnusson, B. Woodman, C. Landles, M. A. Pouladi, M. R. Hayden, A. Khalili-Shirazi, M. W. Lowdell, P. Brundin, G. P. Bates, B. R. Leavitt, T. Moller and S. J. Tabrizi: A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease. J Exp Med 205, 1869-77 (2008)
-
(2008)
J Exp Med
, vol.205
, pp. 1869-1877
-
-
Bjorkqvist, M.1
Wild, E.J.2
Thiele, J.3
Silvestroni, A.4
Andre, R.5
Lahiri, N.6
Raibon, E.7
Lee, R.V.8
Benn, C.L.9
Soulet, D.10
Magnusson, A.11
Woodman, B.12
Landles, C.13
Pouladi, M.A.14
Hayden, M.R.15
Khalili-Shirazi, A.16
Lowdell, M.W.17
Brundin, P.18
Bates, G.P.19
Leavitt, B.R.20
Moller, T.21
Tabrizi, S.J.22
more..
-
167
-
-
67650095269
-
Beyond the brain: Widespread pathology in Huntington's disease
-
J. M. van der Burg, M. Bjorkqvist and P. Brundin: Beyond the brain: widespread pathology in Huntington's disease. Lancet Neurol 8, 765-74 (2009)
-
(2009)
Lancet Neurol
, vol.8
, pp. 765-774
-
-
Van Der Burg, J.M.1
Bjorkqvist, M.2
Brundin, P.3
-
168
-
-
36949012566
-
Huntington disease models and human neuropathology: Similarities and differences
-
J. P. Vonsattel: Huntington disease models and human neuropathology: similarities and differences. Acta Neuropathol 115, 55-69 (2008)
-
(2008)
Acta Neuropathol
, vol.115
, pp. 55-69
-
-
Vonsattel, J.P.1
-
169
-
-
36749033738
-
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits
-
M. DiFiglia, M. Sena-Esteves, K. Chase, E. Sapp, E. Pfister, M. Sass, J. Yoder, P. Reeves, R. K. Pandey, K. G. Rajeev, M. Manoharan, D. W. Sah, P. D. Zamore and N. Aronin: Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci U S A 104, 17204-9 (2007)
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17204-17209
-
-
DiFiglia, M.1
Sena-Esteves, M.2
Chase, K.3
Sapp, E.4
Pfister, E.5
Sass, M.6
Yoder, J.7
Reeves, P.8
Pandey, R.K.9
Rajeev, K.G.10
Manoharan, M.11
Sah, D.W.12
Zamore, P.D.13
Aronin, N.14
-
170
-
-
0035978743
-
Amyotrophic lateral sclerosis
-
L. P. Rowland and N. A. Shneider: Amyotrophic lateral sclerosis. N Engl J Med 344, 1688-700 (2001)
-
(2001)
N Engl J Med
, vol.344
, pp. 1688-1700
-
-
Rowland, L.P.1
Shneider, N.A.2
-
171
-
-
0031845040
-
Oxidative damage in the central nervous system: Protection by melatonin
-
R. J. Reiter: Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 56, 359-84 (1998)
-
(1998)
Prog Neurobiol
, vol.56
, pp. 359-384
-
-
Reiter, R.J.1
-
172
-
-
0036482282
-
Chemical and physical properties and potential mechanisms: Melatonin as a broad spectrum antioxidant and free radical scavenger
-
D. X. Tan, R. J. Reiter, L. C. Manchester, M. T. Yan, M. El-Sawi, R. M. Sainz, J. C. Mayo, R. Kohen, M. Allegra and R. Hardeland: Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem 2, 181-97 (2002)
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 181-197
-
-
Tan, D.X.1
Reiter, R.J.2
Manchester, L.C.3
Yan, M.T.4
El-Sawi, M.5
Sainz, R.M.6
Mayo, J.C.7
Kohen, R.8
Allegra, M.9
Hardeland, R.10
-
173
-
-
30944449193
-
The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis
-
N. Buscemi, B. Vandermeer, N. Hooton, R. Pandya, L. Tjosvold, L. Hartling, G. Baker, T. P. Klassen and S. Vohra: The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis. J Gen Intern Med 20, 1151-8 (2005)
-
(2005)
J Gen Intern Med
, vol.20
, pp. 1151-1158
-
-
Buscemi, N.1
Vandermeer, B.2
Hooton, N.3
Pandya, R.4
Tjosvold, L.5
Hartling, L.6
Baker, G.7
Klassen, T.P.8
Vohra, S.9
-
174
-
-
33644869714
-
Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: Meta-analysis
-
N. Buscemi, B. Vandermeer, N. Hooton, R. Pandya, L. Tjosvold, L. Hartling, S. Vohra, T. P. Klassen and G. Baker: Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis. BMJ 332, 385-93 (2006)
-
(2006)
BMJ
, vol.332
, pp. 385-393
-
-
Buscemi, N.1
Vandermeer, B.2
Hooton, N.3
Pandya, R.4
Tjosvold, L.5
Hartling, L.6
Vohra, S.7
Klassen, T.P.8
Baker, G.9
-
175
-
-
36349021288
-
Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects
-
P. Lemoine, T. Nir, M. Laudon and N. Zisapel: Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. J Sleep Res 16, 372-80 (2007)
-
(2007)
J Sleep Res
, vol.16
, pp. 372-380
-
-
Lemoine, P.1
Nir, T.2
Laudon, M.3
Zisapel, N.4
-
176
-
-
35649020265
-
Efficacy of prolonged release melatonin in insomnia patients aged 55-80 years: Quality of sleep and next-day alertness outcomes
-
A. G. Wade, I. Ford, G. Crawford, A. D. McMahon, T. Nir, M. Laudon and N. Zisapel: Efficacy of prolonged release melatonin in insomnia patients aged 55-80 years: quality of sleep and next-day alertness outcomes. Curr Med Res Opin 23, 2597-605 (2007)
-
(2007)
Curr Med Res Opin
, vol.23
, pp. 2597-2605
-
-
Wade, A.G.1
Ford, I.2
Crawford, G.3
McMahon, A.D.4
Nir, T.5
Laudon, M.6
Zisapel, N.7
-
177
-
-
10644278744
-
Effects of add-on melatonin administration on antioxidant enzymes in children with epilepsy taking carbamazepine monotherapy: A randomized, double-blind, placebo-controlled trial
-
M. Gupta, Y. K. Gupta, S. Agarwal, S. Aneja, M. Kalaivani and K. Kohli: Effects of add-on melatonin administration on antioxidant enzymes in children with epilepsy taking carbamazepine monotherapy: a randomized, double-blind, placebo-controlled trial. Epilepsia 45, 1636-9 (2004)
-
(2004)
Epilepsia
, vol.45
, pp. 1636-1639
-
-
Gupta, M.1
Gupta, Y.K.2
Agarwal, S.3
Aneja, S.4
Kalaivani, M.5
Kohli, K.6
-
178
-
-
9144249625
-
A randomized, double-blind, placebo controlled trial of melatonin add-on therapy in epileptic children on valproate monotherapy: Effect on glutathione peroxidase and glutathione reductase enzymes
-
M. Gupta, Y. K. Gupta, S. Agarwal, S. Aneja and K. Kohli: A randomized, double-blind, placebo controlled trial of melatonin add-on therapy in epileptic children on valproate monotherapy: effect on glutathione peroxidase and glutathione reductase enzymes. Br J Clin Pharmacol 58, 542-7 (2004)
-
(2004)
Br J Clin Pharmacol
, vol.58
, pp. 542-547
-
-
Gupta, M.1
Gupta, Y.K.2
Agarwal, S.3
Aneja, S.4
Kohli, K.5
-
179
-
-
0038346728
-
Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: A randomized trial
-
P. Lissoni, M. Chilelli, S. Villa, L. Cerizza and G. Tancini: Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: a randomized trial. J Pineal Res 35, 12-5 (2003)
-
(2003)
J Pineal Res
, vol.35
, pp. 12-15
-
-
Lissoni, P.1
Chilelli, M.2
Villa, S.3
Cerizza, L.4
Tancini, G.5
-
180
-
-
0037093071
-
Melatonin: From basic research to cancer treatment clinics
-
C. R. T. Jr. Vijayalaxmi, R. J. Reiter and T. S. Herman: Melatonin: from basic research to cancer treatment clinics. J Clin Oncol 20, 2575-601 (2002)
-
(2002)
J Clin Oncol
, vol.20
, pp. 2575-2601
-
-
Vijayalaxmi Jr., C.R.T.1
Reiter, R.J.2
Herman, T.S.3
-
181
-
-
0030663670
-
Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: A p53-independent induction of p21WAF1/CIP1 via C/EBPbeta
-
R. Chinery, J. A. Brockman, M. O. Peeler, Y. Shyr, R. D. Beauchamp and R. J. Coffey: Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta. Nat Med 3, 1233-41 (1997)
-
(1997)
Nat Med
, vol.3
, pp. 1233-1241
-
-
Chinery, R.1
Brockman, J.A.2
Peeler, M.O.3
Shyr, Y.4
Beauchamp, R.D.5
Coffey, R.J.6
-
182
-
-
84860733676
-
No effect of melatonin to modify surgical-stress response after major vascular surgery: A randomised placebo-controlled trial
-
B. Kucukakin, M. Wilhelmsen, J. Lykkesfeldt, R. J. Reiter, J. Rosenberg and I. Gogenur: No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial. Eur J Vasc Endovasc Surg 40, 461-7 (2010)
-
(2010)
Eur J Vasc Endovasc Surg
, vol.40
, pp. 461-467
-
-
Kucukakin, B.1
Wilhelmsen, M.2
Lykkesfeldt, J.3
Reiter, R.J.4
Rosenberg, J.5
Gogenur, I.6
-
183
-
-
77956398130
-
No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: A randomized placebo-controlled trial
-
B. Kucukakin, M. Klein, J. Lykkesfeldt, R. J. Reiter, J. Rosenberg and I. Gogenur: No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial. Acta Anaesthesiol Scand 54, 1121-7 (2010)
-
(2010)
Acta Anaesthesiol Scand
, vol.54
, pp. 1121-1127
-
-
Kucukakin, B.1
Klein, M.2
Lykkesfeldt, J.3
Reiter, R.J.4
Rosenberg, J.5
Gogenur, I.6
-
184
-
-
34548641697
-
Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin
-
C. M. Forrest, G. M. Mackay, N. Stoy, T. W. Stone and L. G. Darlington: Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin. Br J Clin Pharmacol 64, 517-26 (2007)
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 517-526
-
-
Forrest, C.M.1
Mackay, G.M.2
Stoy, N.3
Stone, T.W.4
Darlington, L.G.5
-
185
-
-
60149093129
-
Phytomelatonin: A review
-
S. D. Paredes, A. Korkmaz, L. C. Manchester, D. X. Tan and R. J. Reiter: Phytomelatonin: a review. J Exp Bot 60, 57-69 (2009)
-
(2009)
J Exp Bot
, vol.60
, pp. 57-69
-
-
Paredes, S.D.1
Korkmaz, A.2
Manchester, L.C.3
Tan, D.X.4
Reiter, R.J.5
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