The use of melatonin in Alzheimer's disease

Neuroendocrinology Letters

Volumn 23, Issue SUPPL. 1, 2002, Pages 20-23

  Cardinali, Daniel P ^a   Brusco, Luis I ^a   Liberczuk, Cynthia ^a   Furio, Analía M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Aging; Alzheimer's disease; Cognitive impairment; Melatonin; Sleep disorders

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BENZODIAZEPINE DERIVATIVE; MELATONIN; THIORIDAZINE; TRICYCLIC ANTIDEPRESSANT AGENT;

AGED; AGITATION; ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; BEHAVIOR DISORDER; COGNITIVE DEFECT; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG USE; FEMALE; HORMONE INHIBITION; HORMONE RELEASE; HUMAN; MALE; MONOZYGOTIC TWINS; REVIEW; SLEEP DISORDER; SLEEP PATTERN;

EID: 0036264476     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (29)

1. Treatment of sleep disturbance in Alzheimer's disease
2. Sleep disturbances in community-dwelling patients with Alzheimer's disease
3. Sleep disturbances in patients with mild-stage Alzheimer's disease
4. Chronic hypnotic use: Deadly risks, doubtful benefit
5. Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's disease
6. The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia
7. Circadian rhythms and sleep in human aging
8. Supplementary administration of artificial bright light and melatonin as potent treatment for disorganized circadian rest-activity and dysfunctional autonomic and neuroendocrine systems in institutionalized demented elderly persons
9. Circadian locomotor activity and core-body temperature rhythms in Alzheimer's disease
10. Assessment and management of "sundowning" phenomena
11. Sleep electroencephalographic and eye-movement patterns in patients with chronic brain syndrome
12. The treatment of sundowning. A selective review of pharmacological and nonpharmacological studies
13. Age-dependent reduction in serum melatonin concentrations in healthy human subjects
14. Chrono-neuroendocrinological aspects of physiological aging and senile dementia
15. Low urinary 6-sulphatoxymelatonin levels in patients with coronary artery disease
16. Lack of changes in serum prolactin, FSH, TSH, and estradiol after melatonin treatment in doses that improve sleep and reduce benzodiazepine consumption in sleep-disturbed, middle-aged, and elderly patients
17. Actigraphic sleep-wake patterns and urinary 6-sulfatoxymelatonin excretion in patients with Alzheimer's disease
18. Diminished melatonin secretion in the elderly caused by insufficient environmental illumination
19. Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype
20. Behavioral effects of melatonin treatment in non-human primates
21. Effects of melatonin in elderly patients with sleep disturbance. A pilot study
22. Melatonin treatment stabilizes chronobiologic and cognitive symptoms in Alzheimer's disease
23. Monozygotic twins with Alzheimer's disease treated with melatonin: Case report
24. Melatonin for treatment of sundowning in elderly persons with demen
25. Effects of melatonin in two individuals with Alzheimer's disease
26. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease
27. Polysomnographic study of the effect of melatonin on sleep in elderly patients with chronic primary insomnia
28. Neuroendocrine rhythms and sleep in aging men
29. Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system