메뉴 건너뛰기




Volumn 9, Issue 3-4, 2000, Pages 160-171

Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo

Author keywords

Antioxidant; Cancer; Free radicals; Ischemia reperfusion injury; Melatonin; Neurogeneration

Indexed keywords

MELATONIN;

EID: 0033925920     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000014636     Document Type: Article
Times cited : (259)

References (86)
  • 3
    • 0031743140 scopus 로고    scopus 로고
    • Suppression of oxygen toxicity by melatonin
    • Reiter RJ, Tan DX, Qi W: Suppression of oxygen toxicity by melatonin. Acta Pharmacol Sin 1998; 19: 575-581.
    • (1998) Acta Pharmacol Sin , vol.19 , pp. 575-581
    • Reiter, R.J.1    Tan, D.X.2    Qi, W.3
  • 4
    • 0031845040 scopus 로고    scopus 로고
    • Oxidative damage in the central nervous system: Protection by melatonin
    • Reiter RJ: Oxidative damage in the central nervous system: Protection by melatonin. Prog Neurobiol 1998; 56:359-384.
    • (1998) Prog Neurobiol , vol.56 , pp. 359-384
    • Reiter, R.J.1
  • 6
    • 0028178826 scopus 로고
    • Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole
    • Tan DX, Reiter RJ, Chen LD, Poeg-geler B, Manchester LC, Barlow-Walden LR: Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis 1994;15:215-218.
    • (1994) Carcinogenesis , vol.15 , pp. 215-218
    • Tan, D.X.1    Reiter, R.J.2    Chen, L.D.3    Poeg-Geler, B.4    Manchester, L.C.5    Barlow-Walden, L.R.6
  • 7
    • 10544255343 scopus 로고    scopus 로고
    • Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats
    • Manev H, Uz T, Kharlamov A, Joo JY: Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats. FASEB J 1996;10:1546-1551.
    • (1996) FASEB J , vol.10 , pp. 1546-1551
    • Manev, H.1    Uz, T.2    Kharlamov, A.3    Joo, J.Y.4
  • 9
    • 0031823823 scopus 로고    scopus 로고
    • Melatonin as a hydroxyl radical scavenger
    • Stasica P, Ulanski P, Rosiak JM: Melatonin as a hydroxyl radical scavenger. J Pineal Res 1998;25:65-66.
    • (1998) J Pineal Res , vol.25 , pp. 65-66
    • Stasica, P.1    Ulanski, P.2    Rosiak, J.M.3
  • 11
    • 0033006251 scopus 로고    scopus 로고
    • Antioxidant properties of melatonin: A pulse radiolysis study
    • Mahal HS, Sharma HS, Mukerjee T: Antioxidant properties of melatonin: A pulse radiolysis study. Free Radic Biol Med 1999;26:557-565.
    • (1999) Free Radic Biol Med , vol.26 , pp. 557-565
    • Mahal, H.S.1    Sharma, H.S.2    Mukerjee, T.3
  • 12
    • 0031981238 scopus 로고    scopus 로고
    • Comparison of the antioxidant activity of melatonin and pi-noline in vivo
    • Pahkla R, Zilmer M, Kullisar M, Rago L: Comparison of the antioxidant activity of melatonin and pi-noline in vivo. J Pineal Res 1998;24: 96-101.
    • (1998) J Pineal Res , vol.24 , pp. 96-101
    • Pahkla, R.1    Zilmer, M.2    Kullisar, M.3    Rago, L.4
  • 13
    • 0033000928 scopus 로고    scopus 로고
    • Cyclic 3-hydroxy-melatonin: A melatonin metabolite generated as a result of hydroxyl radical scavenging
    • Tan DX, Manchester LC, Reiter RJ, Plummer BF: Cyclic 3-hydroxy-melatonin: A melatonin metabolite generated as a result of hydroxyl radical scavenging. Biol Signals Re-cept 1999;8:70-74.
    • (1999) Biol Signals Re-Cept , vol.8 , pp. 70-74
    • Tan, D.X.1    Manchester, L.C.2    Reiter, R.J.3    Plummer, B.F.4
  • 16
    • 0032831961 scopus 로고    scopus 로고
    • Melatonin and its precursors scavenge nitric oxide
    • Noda Y, Mori A, Liburty R, Packer L: Melatonin and its precursors scavenge nitric oxide. J Pineal Res 1999;27:159-163.
    • (1999) J Pineal Res , vol.27 , pp. 159-163
    • Noda, Y.1    Mori, A.2    Liburty, R.3    Packer, L.4
  • 17
    • 0033012719 scopus 로고    scopus 로고
    • Reaction of peroxynitrite with melatonin: A mechanistic study
    • Zhang H, Squadrito GL, Pryor WA: Reaction of peroxynitrite with melatonin: A mechanistic study. Chem Res Toxicol 1999;12:526-534.
    • (1999) Chem Res Toxicol , vol.12 , pp. 526-534
    • Zhang, H.1    Squadrito, G.L.2    Pryor, W.A.3
  • 18
    • 0031420974 scopus 로고    scopus 로고
    • Both melatonin and a putative nuclear receptor agonist CGP 52608 stimulate glutathione peroxidase and glutathione reductase activities in mouse brain in vivo
    • Pablos MI, Guerrero JM, Ortiz GG, Agapito MT, Reiter RJ: Both melatonin and a putative nuclear receptor agonist CGP 52608 stimulate glutathione peroxidase and glutathione reductase activities in mouse brain in vivo. Neuroendocrinol Lett 1997;18:49-58.
    • (1997) Neuroendocrinol Lett , vol.18 , pp. 49-58
    • Pablos, M.I.1    Guerrero, J.M.2    Ortiz, G.G.3    Agapito, M.T.4    Reiter, R.J.5
  • 19
    • 0030914428 scopus 로고    scopus 로고
    • Pharmacological actions of melatonin in oxygen radical pathophysiology
    • Reiter RJ, Tang L, Garcia JJ, Mu-noz-Hoyos A: Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci 1997;60: 2255-2271.
    • (1997) Life Sci , vol.60 , pp. 2255-2271
    • Reiter, R.J.1    Tang, L.2    Garcia, J.J.3    Mu-Noz-Hoyos, A.4
  • 20
    • 0030844416 scopus 로고    scopus 로고
    • Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats
    • Hara M, Iigo M, Ohtani-Kaneko R, Nakamura N, Suzuki T, Reiter RJ, Hirata K: Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats. Biol Signals 1997;6: 90-100.
    • (1997) Biol Signals , vol.6 , pp. 90-100
    • Hara, M.1    Iigo, M.2    Ohtani-Kaneko, R.3    Nakamura, N.4    Suzuki, T.5    Reiter, R.J.6    Hirata, K.7
  • 22
    • 0032032987 scopus 로고    scopus 로고
    • Melatonin enhances tamoxifen’s ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation
    • Garcia JJ, Reiter RJ, Ortiz GG, Oh CS, Tang L, Yu BP, Escames G: Melatonin enhances tamoxifen’s ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation. J Membr Biol 1998;162:59-65.
    • (1998) J Membr Biol , vol.162 , pp. 59-65
    • Garcia, J.J.1    Reiter, R.J.2    Ortiz, G.G.3    Oh, C.S.4    Tang, L.5    Yu, B.P.6    Escames, G.7
  • 23
    • 0027725205 scopus 로고
    • Distribution of melatonin in mammalian tissues: Relative importance of nuclear verses cytosolic localization
    • Menendez-Pelaez A, Reiter RJ: Distribution of melatonin in mammalian tissues: Relative importance of nuclear verses cytosolic localization. J Pineal Res 1993;15:59-69.
    • (1993) J Pineal Res , vol.15 , pp. 59-69
    • Menendez-Pelaez, A.1    Reiter, R.J.2
  • 24
  • 25
    • 0023709008 scopus 로고
    • Neither the pituitary gland nor the sympathetic nervous system is responsible for eliciting the large drop in elevated rat pineal melatonin levels due to swimming
    • Troiani ME, Reiter RJ, Tannen-baum MG, Puig-Domingo M, Guerrero JM, Menendez-Pelaez A: Neither the pituitary gland nor the sympathetic nervous system is responsible for eliciting the large drop in elevated rat pineal melatonin levels due to swimming. J Neural Transm 1988;74:149-160.
    • (1988) J Neural Transm , vol.74 , pp. 149-160
    • Troiani, M.E.1    Reiter, R.J.2    Tannen-Baum, M.G.3    Puig-Domingo, M.4    Guerrero, J.M.5    Menendez-Pelaez, A.6
  • 26
    • 0030020772 scopus 로고    scopus 로고
    • Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat
    • Pohjanvirta R, Laitinen JT, Vakkuri O, Linden J, Kokkola T, Unkila M, Tuomisto J: Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat. Toxicology 1996;107:85-97.
    • (1996) Toxicology , vol.107 , pp. 85-97
    • Pohjanvirta, R.1    Laitinen, J.T.2    Vakkuri, O.3    Linden, J.4    Kokkola, T.5    Unkila, M.6    Tuomisto, J.7
  • 30
    • 0033305177 scopus 로고    scopus 로고
    • High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus
    • Skinner DC, Malpaux B: High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology 1999;140:4399-4405.
    • (1999) Endocrinology , vol.140 , pp. 4399-4405
    • Skinner, D.C.1    Malpaux, B.2
  • 31
    • 0031263656 scopus 로고    scopus 로고
    • Antioxidative protection in a high-melatonin organism: The dinoflagellate Gonyaulax polyedra is rescued from lethal stress by strongly elevated, but physiologically possible concentrations of melatonin
    • Antolin I, Obst B, Burkhardt S, Har-deland R: Antioxidative protection in a high-melatonin organism: The dinoflagellate Gonyaulax polyedra is rescued from lethal stress by strongly elevated, but physiologically possible concentrations of melatonin. J Pineal Res 1997;23:182-190.
    • (1997) J Pineal Res , vol.23 , pp. 182-190
    • Antolin, I.1    Obst, B.2    Burkhardt, S.3    Har-Deland, R.4
  • 32
    • 0032878234 scopus 로고    scopus 로고
    • Melatonin induces y-glutamyl-cysteine synthetase mediated by activator protein-1 in human vascular endothelial cells
    • Urata Y, Honma S, Goto S, Todoro-ki S, Iida T, Cho S, Honma K, Kon-do T: Melatonin induces y-glutamyl-cysteine synthetase mediated by activator protein-1 in human vascular endothelial cells. Free Radic Biol Med 1999;27:838-847.
    • (1999) Free Radic Biol Med , vol.27 , pp. 838-847
    • Urata, Y.1    Honma, S.2    Goto, S.3    Todoro-Ki, S.4    Iida, T.5    Cho, S.6    Honma, K.7    Kon-Do, T.8
  • 33
    • 0002560603 scopus 로고
    • Extra-pineal melatonin in the retina: Its regulation and physiological function;
    • Reiter RJ (ed):, New York, Liss
    • Pang SF, Allen AE: Extra-pineal melatonin in the retina: Its regulation and physiological function; in Reiter RJ (ed): Pineal Research Reviews. New York, Liss, 1986, vol IV, pp 55-95.
    • (1986) Pineal Research Reviews. , vol.4 , pp. 55-95
    • Pang, S.F.1    Allen, A.E.2
  • 35
    • 0032949247 scopus 로고    scopus 로고
    • Melatonin as an antioxidant in retinal photoreceptor cells
    • Marchiafava PL, Longoni B: Melatonin as an antioxidant in retinal photoreceptor cells. J Pineal Res 1999;26:184-189.
    • (1999) J Pineal Res , vol.26 , pp. 184-189
    • Marchiafava, P.L.1    Longoni, B.2
  • 36
    • 0029382404 scopus 로고
    • Permeability of pure lipid bilayers to melatonin
    • Costa EJX, Lopes RH, Lamy-Freund MT: Permeability of pure lipid bilayers to melatonin. J Pineal Res 1995;19:123-124.
    • (1995) J Pineal Res , vol.19 , pp. 123-124
    • Costa, E.1    Lopes, R.H.2    Lamy-Freund, M.T.3
  • 38
    • 0031437791 scopus 로고    scopus 로고
    • Differential behaviour of cell membranes towards iron-induced oxidative damage and the effects of melatonin
    • Tang PL, Xu MF, Qian ZM: Differential behaviour of cell membranes towards iron-induced oxidative damage and the effects of melatonin. Biol Signals 1997;6:291-300.
    • (1997) Biol Signals , vol.6 , pp. 291-300
    • Tang, P.L.1    Xu, M.F.2    Qian, Z.M.3
  • 39
    • 0031971571 scopus 로고    scopus 로고
    • Reiter RJ: 8-Amino-levulenic acid-induced lipid peroxidation in rat kidney and liver is attenuated by melatonin: An in vitro and in vivo study
    • Carneiro RCG, Reiter RJ: 8-Amino-levulenic acid-induced lipid peroxidation in rat kidney and liver is attenuated by melatonin: An in vitro and in vivo study. J Pineal Res 1998;24:131-136.
    • (1998) J Pineal Res , vol.24 , pp. 131-136
    • Carneiro, R.1
  • 42
    • 0031910656 scopus 로고    scopus 로고
    • Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats
    • Tang L, Reiter RJ, Li ZR, Ortiz GG, Yu BP, Garcia JJ: Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats. Mol Cell Biochem 1998; 178:299-303.
    • (1998) Mol Cell Biochem , vol.178 , pp. 299-303
    • Tang, L.1    Reiter, R.J.2    Li, Z.R.3    Ortiz, G.G.4    Yu, B.P.5    Garcia, J.J.6
  • 43
    • 0032931407 scopus 로고    scopus 로고
    • Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain
    • Wakatsuki A, Okatani Y, Izumiya C, Ikenoue N: Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain. J Pineal Res 1999;26:147-152.
    • (1999) J Pineal Res , vol.26 , pp. 147-152
    • Wakatsuki, A.1    Okatani, Y.2    Izumiya, C.3    Ikenoue, N.4
  • 44
    • 0032698584 scopus 로고    scopus 로고
    • Melatonin and protection from genetic damage in blood and bone marrow: Whole-body irradiation studies in mice
    • Vijayalaxmi, Meltz ML, Reiter RJ, Herman TS: Melatonin and protection from genetic damage in blood and bone marrow: Whole-body irradiation studies in mice. J Pineal Res 1999;27:221-225.
    • (1999) J Pineal Res , vol.27 , pp. 221-225
    • Vijayalaxmi, M.M.1    Reiter, R.J.2    Herman, T.S.3
  • 45
    • 0032996057 scopus 로고    scopus 로고
    • Protective effect of melatonin on zymosan-induced cellular damage
    • Cuzzocrea S, Caputi AP: Protective effect of melatonin on zymosan-induced cellular damage. Biol Signals Recept 1999;8:136-142.
    • (1999) Biol Signals Recept , vol.8 , pp. 136-142
    • Cuzzocrea, S.1    Caputi, A.P.2
  • 46
    • 0008516153 scopus 로고    scopus 로고
    • Effects of melatonin on DNA damage and repair in rat brain following a transient cerebral ischemia (Abstract)
    • Sun EY, Lin X, Zhang LM, Lu SD, Pan S: Effects of melatonin on DNA damage and repair in rat brain following a transient cerebral ischemia (abstract). Biol Signals Recept 2000; 9:69.
    • (2000) Biol Signals Recept , vol.9 , pp. 69
    • Sun, E.Y.1    Lin, X.2    Zhang, L.M.3    Lu, S.D.4    Pan, S.5
  • 47
    • 0032846899 scopus 로고    scopus 로고
    • Melatonin protects human red blood cells from oxidative hemolysis: New insights into the radicalscavenging activity
    • Tesoriere L, D’arpa D, Conti S, Giaccone V, Pinaudi AM, Livrea MA: Melatonin protects human red blood cells from oxidative hemolysis: New insights into the radicalscavenging activity. J Pineal Res 1999;27:95-105.
    • (1999) J Pineal Res , vol.27 , pp. 95-105
    • Tesoriere, L.1    D’arpa, D.2    Conti, S.3    Giaccone, V.4    Pinaudi, A.M.5    Livrea, M.A.6
  • 48
    • 0032979082 scopus 로고    scopus 로고
    • Interactions of melatonin with membrane models: Portioning of melatonin in AOT and lecithin reversed micelles
    • Ceraulo L, Ferrugia M, Tesoriere L, Segreto S, Livrea MA, Turco Livrea V: Interactions of melatonin with membrane models: Portioning of melatonin in AOT and lecithin reversed micelles. J Pineal Res 1999; 26:108-112.
    • (1999) J Pineal Res , vol.26 , pp. 108-112
    • Ceraulo, L.1    Ferrugia, M.2    Tesoriere, L.3    Segreto, S.4    Livrea, M.A.5    Turco Livrea, V.6
  • 50
    • 0033451022 scopus 로고    scopus 로고
    • Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration
    • El-Sokkary GH, Reiter RJ, Tan DX, Kim SJ, Cabrera J: Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration. Alcohol Alcohol 1999;34:842-850.
    • (1999) Alcohol Alcohol , vol.34 , pp. 842-850
    • El-Sokkary, G.H.1    Reiter, R.J.2    Tan, D.X.3    Kim, S.J.4    Cabrera, J.5
  • 53
    • 0031856211 scopus 로고    scopus 로고
    • Circadian variations in the rat serum total antioxidant status: Correlation with melatonin levels
    • Benot S, Molinero P, Soutto M, Go-berna R, Guerrero JM: Circadian variations in the rat serum total antioxidant status: Correlation with melatonin levels. J Pineal Res 1998; 25:1-4.
    • (1998) J Pineal Res , vol.25 , pp. 1-4
    • Benot, S.1    Molinero, P.2    Soutto, M.3    Go-Berna, R.4    Guerrero, J.M.5
  • 54
    • 0030013228 scopus 로고    scopus 로고
    • Oxidative stress in the production and expression of neurotoxic P-amyloid
    • Richardson JS, Zhou Y: Oxidative stress in the production and expression of neurotoxic P-amyloid. Rest Neurol Neurosci 1996;9:207-211.
    • (1996) Rest Neurol Neurosci , vol.9 , pp. 207-211
    • Richardson, J.S.1    Zhou, Y.2
  • 55
    • 0031870324 scopus 로고    scopus 로고
    • Oxidative toxicity in models of neurodegeneration: Responses to melatonin
    • Reiter RJ, Garcia JJ, Pie J: Oxidative toxicity in models of neurodegeneration: Responses to melatonin. Rest Neurol Neurosci 1998; 12:135-142.
    • (1998) Rest Neurol Neurosci , vol.12 , pp. 135-142
    • Reiter, R.J.1    Garcia, J.J.2    Pie, J.3
  • 59
    • 0029196202 scopus 로고
    • Ischemic heart disease and antioxidants: Mechanistic aspects of oxidative injury and its prevention
    • Janeiro DR: Ischemic heart disease and antioxidants: Mechanistic aspects of oxidative injury and its prevention. Crit Rev Food Sci Nutr 1995;35:65-81.
    • (1995) Crit Rev Food Sci Nutr , vol.35 , pp. 65-81
    • Janeiro, D.R.1
  • 60
    • 0029112937 scopus 로고
    • Detection of free radical activity during transient global ischemia and recirculation: Effects of intraischemic brain temperature modulation
    • Globus MY, Busto R, Lin B, Schnip-pering H, Ginsberg MD: Detection of free radical activity during transient global ischemia and recirculation: Effects of intraischemic brain temperature modulation. J Neuro-chem 1995;65:1250-1256.
    • (1995) J Neuro-Chem , vol.65 , pp. 1250-1256
    • Globus, M.Y.1    Busto, R.2    Lin, B.3    Schnip-Pering, H.4    Ginsberg, M.D.5
  • 61
    • 0026047662 scopus 로고
    • The aging process: Major risk factor for disease and death
    • Harman D: The aging process: Major risk factor for disease and death. Proc Natl Acad Sci USA 1991;88: 5360-5363.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5360-5363
    • Harman, D.1
  • 62
    • 0031545524 scopus 로고    scopus 로고
    • Aging and oxygen toxicity: Relation to changes in melatonin
    • Reiter RJ: Aging and oxygen toxicity: Relation to changes in melatonin. Age 1997;20:201-213.
    • (1997) Age , vol.20 , pp. 201-213
    • Reiter, R.J.1
  • 63
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis of Alzheimer’s disease
    • Markesbury WR: Oxidative stress hypothesis of Alzheimer’s disease. Free Radic Biol Med 1997;23:134-137.
    • (1997) Free Radic Biol Med , vol.23 , pp. 134-137
    • Markesbury, W.R.1
  • 64
    • 0027283898 scopus 로고
    • Free radicals and their scavengers in Parkinson’s disease
    • Yoshikawa T: Free radicals and their scavengers in Parkinson’s disease. Eur Neurol 1993;33(suppl 1): 60-68.
    • (1993) Eur Neurol , vol.33 , pp. 60-68
    • Yoshikawa, T.1
  • 65
    • 0030347242 scopus 로고    scopus 로고
    • The kynurenine pathway and neurological disease. Therapeutic strategies
    • Heyes MP: The kynurenine pathway and neurological disease. Therapeutic strategies. Adv Exp Med Biol 1996;398:125-129.
    • (1996) Adv Exp Med Biol , vol.398 , pp. 125-129
    • Heyes, M.P.1
  • 68
    • 0344492689 scopus 로고    scopus 로고
    • Monozygotic twins with Alzheimer’s disease treated with melatonin. Case report
    • Brusco LI, Marquez M, Cardinali DP: Monozygotic twins with Alzheimer’s disease treated with melatonin. Case report. J Pineal Res 1998;25:260-263.
    • (1998) J Pineal Res , vol.25 , pp. 260-263
    • Brusco, L.I.1    Marquez, M.2    Cardinali, D.P.3
  • 70
    • 0030843476 scopus 로고    scopus 로고
    • Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress
    • Iacovitti L, Stull ND, Johnston K: Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress. Brain Res 1997;768:317-326.
    • (1997) Brain Res , vol.768 , pp. 317-326
    • Iacovitti, L.1    Stull, N.D.2    Johnston, K.3
  • 71
    • 0031981649 scopus 로고    scopus 로고
    • Melatonin prevents apoptosis induced by 6-hydroxydopamine in neuronal cells. Implications for Parkinson’s disease
    • Mayo JC, Sainz R, Uria H, Antolin I, Esteban MM, Rodriquez C: Melatonin prevents apoptosis induced by 6-hydroxydopamine in neuronal cells. Implications for Parkinson’s disease. J Pineal Res 1998;24:179-192.
    • (1998) J Pineal Res , vol.24 , pp. 179-192
    • Mayo, J.C.1    Sainz, R.2    Uria, H.3    Antolin, I.4    Esteban, M.M.5    Rodriquez, C.6
  • 72
    • 0032104709 scopus 로고    scopus 로고
    • Melatonin plays a protective role in quinolinic acid-induced neurotoxicity in the rat hippocampus
    • Southgate GS, Daya S, Potgieter B: Melatonin plays a protective role in quinolinic acid-induced neurotoxicity in the rat hippocampus. J Chem Neuroanat 1998;14:151-156.
    • (1998) J Chem Neuroanat , vol.14 , pp. 151-156
    • Southgate, G.S.1    Daya, S.2    Potgieter, B.3
  • 74
    • 0033567891 scopus 로고    scopus 로고
    • Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events
    • Blask DE, Sauer LA, Dauchy RT, Holowachuk EW, Ruhoff MS, Kopff HS: Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. Cancer Res 1999;59:4693-4701.
    • (1999) Cancer Res , vol.59 , pp. 4693-4701
    • Blask, D.E.1    Sauer, L.A.2    Dauchy, R.T.3    Holowachuk, E.W.4    Ruhoff, M.S.5    Kopff, H.S.6
  • 75
    • 85025556372 scopus 로고    scopus 로고
    • Increased levels of oxidatively damaged DNA induced by chromi-um(III) and H2O2: Protection by melatonin and related molecules
    • Qi W, Reiter RJ, Tan DX, Manchester LC, Siu AW, Garcia JJ: Increased levels of oxidatively damaged DNA induced by chromi-um(III) and H2O2: Protection by melatonin and related molecules. J Pineal Res, in press.
    • J Pineal Res, in Press.
    • Qi, W.1    Reiter, R.J.2    Tan, D.X.3    Manchester, L.C.4    Siu, A.W.5    Garcia, J.J.6
  • 76
    • 0030596153 scopus 로고    scopus 로고
    • Melatonin and radioprotection from genetic damage: In vivo/in vitro studies with cells from human volunteers
    • Vijayalaxmi, Reiter RJ, Herman TS, Meltz ML: Melatonin and radioprotection from genetic damage: In vivo/in vitro studies with cells from human volunteers. Mutat Res 1996;371:221-228.
    • (1996) Mutat Res , vol.371 , pp. 221-228
    • Vijayalaxmi, R.R.1    Herman, T.S.2    Meltz, M.L.3
  • 77
  • 78
    • 0031203676 scopus 로고    scopus 로고
    • Melatonin prevents increases in neural nitric oxide and cyclic GMP production after transient brain ischemia and reperfusion in the Mongolian gerbil (Meriones ungui-culatus)
    • Guerrero JM, Reiter RJ, Ortiz GG, Pablos MI, Sewerynek E, Chuang JI: Melatonin prevents increases in neural nitric oxide and cyclic GMP production after transient brain ischemia and reperfusion in the Mongolian gerbil (Meriones ungui-culatus). J Pineal Res 1997;23:24-31.
    • (1997) J Pineal Res , vol.23 , pp. 24-31
    • Guerrero, J.M.1    Reiter, R.J.2    Ortiz, G.G.3    Pablos, M.I.4    Sewerynek, E.5    Chuang, J.I.6
  • 79
    • 0033509001 scopus 로고    scopus 로고
    • Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia
    • Kilic E, Ozdemir YG, Bolay H, Kel-estimur H, Dalkara T: Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia. J Cerebr Blood Flow Metab 1999;19:511-518.
    • (1999) J Cerebr Blood Flow Metab , vol.19 , pp. 511-518
    • Kilic, E.1    Ozdemir, Y.G.2    Bolay, H.3    Kel-Estimur, H.4    Dalkara, T.5
  • 80
    • 85025556298 scopus 로고    scopus 로고
    • Melatonin protects against focal cerebral ischaemia in the rat (Abstract)
    • Pei Z, Pang SF, Cheung RTF: Melatonin protects against focal cerebral ischaemia in the rat (abstract). Biol Signals Recept 2000;9:65.
    • (2000) Biol Signals Recept , vol.9 , pp. 65
    • Pei, Z.1    Pang, S.F.2    Cheung, R.3
  • 82
  • 84
    • 0026830761 scopus 로고
    • The aging pineal and its physiological consequences
    • Reiter RJ: The aging pineal and its physiological consequences. Bioessays 1992;14:169-175.
    • (1992) Bioessays , vol.14 , pp. 169-175
    • Reiter, R.J.1
  • 85
    • 0031266522 scopus 로고    scopus 로고
    • New actions of melatonin and their relevance to biometeorology
    • Hardeland R: New actions of melatonin and their relevance to biometeorology. Int J Biometeorol 1997; 41:47-57.
    • (1997) Int J Biometeorol , vol.41 , pp. 47-57
    • Hardeland, R.1
  • 86
    • 0344069780 scopus 로고    scopus 로고
    • Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats
    • Jahnke G, Marr M, Myers C, Wilson R, Travlos G, Price C: Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats. Toxicol Res 1999;50:271-279.
    • (1999) Toxicol Res , vol.50 , pp. 271-279
    • Jahnke, G.1    Marr, M.2    Myers, C.3    Wilson, R.4    Travlos, G.5    Price, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.