Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: Implications for neuroprotection/neurodegeneration?

Journal of Neurochemistry

Volumn 86, Issue 1, 2003, Pages 228-237

  Gegg, M E ^a   Beltran, B ^c   Salas Pino, S ^d   Bolanos, J P ^d   Clark, J B ^a   Moncada, S ^b   Heales, S J R ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

glutamyltranspeptidase; Astrocytes; Glutamate cysteine ligase; Glutathione; Neurones; Nitric oxide

Indexed keywords

1 [(2 AMINOETHYL) N (2 AMMONIOETHYL)AMINO]DIAZEN 1 IUM 1,2 DIOLATE; CYSTEINYLGLYCINE; GAMMA GLUTAMYLTRANSFERASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; NITRIC OXIDE; NITRIC OXIDE DONOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL DEATH; CELL FUNCTION; DRUG EFFECT; GLUTATHIONE METABOLISM; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; RESPIRATORY CHAIN;

ANIMALS; ASTROCYTES; CELLS, CULTURED; ELECTRON TRANSPORT; GAMMA-GLUTAMYLTRANSFERASE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; NITRIC OXIDE DONORS; RATS; RATS, WISTAR; RNA, MESSENGER; TRIAZENES;

ANIMALIA;

EID: 0038308447     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01821.x     Document Type: Article

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