Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator

Journal of Pineal Research

Volumn 36, Issue 3, 2004, Pages 171-176

  Kilic, Ertugrul ^a,c   Kilic, Ülkan ^a   Yulug, Burak ^a   Hermann, Dirk M ^a   Reiter, Russel J ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Caspase 3 activity; Free radical scavenging; Intraluminal thread occlusion; Ischemia reperfusion; Melatonin; Thrombolysis; Tissue plasminogen activator

Indexed keywords

ALTEPLASE; CASPASE 3; FREE RADICAL; MELATONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOT LYSIS; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME INHIBITION; IMMUNOCYTOCHEMISTRY; LASER DOPPLER FLOWMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN;

EID: 1842557679     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1600-079X.2003.00115.x     Document Type: Article

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