Identification of highly elevated levels of melatonin in bone marrow: Its origin and significance

Biochimica et Biophysica Acta - General Subjects

Volumn 1472, Issue 1-2, 1999, Pages 206-214

  Tan, Dun Xian ^a   Manchester, Lucien C ^a   Reiter, Russel J ^a   Qi, Wen Bo ^a   Zhang, Ming ^a   Weintraub, Susan T ^a,b   Cabrera, Javier ^a   Sainz, Rosa M ^a   Mayo, Juan C ^a  

^a Univ Texas Hlth Sci Ctr 7703 F ^*  (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Antioxidant; Bone marrow; Free radicals; Immunocompetence; Melatonin

Indexed keywords

MELATONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; HEMATOPOIETIC CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOCYTOCHEMISTRY; LYMPHOCYTE; MALE; MASS SPECTROMETRY; NONHUMAN; OXIDATIVE STRESS; PINEAL BODY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

ACETYLSEROTONIN N-METHYLTRANSFERASE; ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; BONE MARROW; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMMUNOHISTOCHEMISTRY; MALE; MELATONIN; PINEAL GLAND; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032829442     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(99)00125-7     Document Type: Article

References (47)

1. Reiter R.J. The pineal and its hormones in the control of reproduction in mammals. Endocr. Rev. 1:1980;109-131.
2. Reiter R.J. Melatonin: the chemical expression of darkness. Mol. Cell. Endocrinol. 79:1991;C153-C158.
3. S.F. Pang, A.E. Allen, Extra-pineal melatonin in the retina: its regulation and physiological function, in: R.J. Reiter (Ed.), Pineal Research Review, vol. 4, Alan R. Liss, New York, 1986, pp. 55-95.
4. Menendez-Pelaez A., Howes K.A., Gonzalez-Brito A., Reiter R.J. N-Acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin levels in the Harderian glands of the female Syrian hamster: changes during the light:dark cycle and the effects of 6-chlorophenylalanine administration. Biochem. Biophys. Res. Commun. 145:1987;1231-1238.
5. Huether G., Poeggeler B., Reimer A., George A. Effect of tryptophan administration on circulating melatonin levels in chicks and rats: evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract. Life Sci. 51:1992;945-953.
6. Itoh M.T., Ishizuka B., Kudo Y., Fusama S., Amemiya A., Sumi Y. Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O-methyltransferase in rat ovary. Mol. Cell. Endocrinol. 136:1997;7-13.
7. Tijimes M., Pedraza R., Valladares L. Melatonin in the rat testis: evidence for local synthesis. Steroids. 61:1996;65-68.
8. Manchester L.C., Poeggeler B., Alvares F.L., Ogden G.B., Reiter R.J. Melatonin immunoreactivity in the photosynthetic prokaryote, Rhodospirillum rubrum: implications for an ancient antioxidant system. Cell. Mol. Biol. Res. 41:1995;391-395.
9. Reiter R.J. Pineal melatonin: cell biology of its synthesis and its physiological interactions. Endocr. Rev. 12:1991;151-180.
10. Hill S., Blask D.E. Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture. Cancer Res. 48:1988;6121-6126.
11. Maestroni G.J.M., Conti A., Pierpaoli W. Role of the pineal gland in immunity: circadian synthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone. J. Neuroimmunol. 13:1986;19-30.
12. Tan D.-X., Chen L.-D., Poeggeler B., Manchester L.C., Reiter R.J. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr. J. 1:1993;57-60.
13. Reiter R.J., Tan D.-X., Poeggeler B., Menendez-Pelaez A., Chen L.-D., Saarela S. Melatonin as free radical scavenger: implications for aging and age-related diseases. Ann. New York Acad. Sci. 719:1994;1-12.
14. Reiter R.J. Oxidative damage in the central nervous system: protection by melatonin. Prog. Neurobiol. 56:1998;359-384.
15. Montilla P.L., Tunez I.F., de Agueda C.M., Gascon F.L., Lopez-Soria J.V. Protective role of melatonin and retinol palmitate in oxidative stress and hyperlipidemic nephropathy induced by adriamycin in rats. J. Pineal Res. 25:1998;86-93.
16. Princ F.G., Maxit A.G., Cardalda C., Batlle A., Juknat A.A. In vivo protection by melatonin against delta-aminolevulinic acid-induced oxidative damage and its antioxidant effect on the activity of haem enzymes. J. Pineal Res. 24:1998;1-8.
17. Tan D.-X., Poeggeler B., Reiter R.J., Chen L.-D., Manchester L.C., Barlow-Walden L.R. The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. Cancer Lett. 70:1993;65-70.
18. Tan D.-X., Reiter R.J., Chen L.D., Poeggeler B., Manchester L.C., Barlow-Walden L.R. Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis. 15:1994;215-218.
19. Vijayalaxmi, M.L. Meltz, R.J. Reiter, T.S. Herman, Melatonin and protection from genetic damage in bone marrow and blood elements: whole-body irradiation studies in mice, J. Pineal Res., in press.
20. Melchiorri D., Ortiz G.G., Reiter R.J., Sewerynek E., Daniels W.M.U., Pablos M.I., Nistico G. Melatonin reduces paraquat-induced genotoxicity in mice. Toxicol. Lett. 95:1998;103-108.
21. Maestroni G.J., Conti A., Lissoni P. Colony-stimulating activity and hematopoietic rescue from cancer chemotherapy compounds are induced by melatonin via endogenous interleukin 4. Cancer Res. 54:1994;4740-4743.
22. Rapozzi V., Zorzet S., Comelli M., Mavelli I., Perissin L., Giraldi T. Melatonin decreases bone marrow and lymphatic toxicity of adriamycin in mice bearing TLX5 lymphoma. Life Sci. 63:1998;1701-1713.
23. A. Conti, G.J.M. Maestroni, Endogenous melatonin in serum, pineal gland and bone marrow of inbred and outbred mice, in: Thymus and Pineal Gland in Neuroimmunoendocrinology, Swieradow Zdrog, 1998, 22B (abstract).
24. Hoffman R.A., Reiter R.J. Rapid pinealectomy in hamsters and other small rodents. Anat. Rec. 153:1965;19-22.
25. Gibbs F.P., Vriend J. Counterantigonadotropic effect of melatonin administered via the drinking water. Endocrinology. 113:1983;1447-1451.
26. Oaknin-Bendahan S., Anis Y., Nir I., Zisapel N. Effects of long-term administration of melatonin and putative antagonist on the ageing rat. NeuroReport. 6:1995;785-788.
27. Fraser S., Cowen P., Franklin M., Franey C., Arendt J. Direct radioimmunoassay for melatonin in plasma. Clin. Chem. 29:1983;396-397.
28. Deguchi T., Axelrod J. Sensitive assay for serotonin N-acetyltransferase activity in rat pineal. Anal. Biochem. 50:1972;174-179.
29. Axelrod J., Wurtman R.J., Snyder S.H. Control of hydroxyindole-O-methyl transferase activity in the rat pineal gland by environmental lighting. J. Biol. Chem. 240:1965;949-954.
30. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
31. Lahiri D.K., Davis D., Adkins M., Nurnberger J.I. Jr. Factors that influence radioimmunoassay of human plasma melatonin: a modified column procedure to eliminate interference. Biochem. Med. Metab. Biol. 49:1993;36-50.
32. Laudon M., Zisapel N. Melatonin binding proteins identified in the rat brain by affinity labeling. FEBS Lett. 288:1991;105-108.
33. Lahiri D.K., Davis D., Nurnberger J.I. Jr. Melatonin-like immunoreactivity in the presence of different chemicals as determined by radioimmunoassay. Biochem. Med. Metab. Biol. 51:1994;51-54.
34. Messner M., Hardeland R., Rodenbeck A., Huether G. Tissue retention and subcellular distribution of continuously infused melatonin in rats under near physiological conditions. J. Pineal Res. 49:1998;251-259.
35. Terashima T., Wiggs B., English D., Hogg J.C., van Eeden S.F. The effect of cigarette smoking on the bone marrow. Am. J. Respir. Crit. Care Med. 155:1997;1021-1026.
36. Wright E.G. Radiation-induced genomic instability in haemopoietic cells. Int. J. Radiat. Biol. 74:1998;681-687.
37. Sharma R.N., Deva C., Behera D., Khanduja K.L. Reactive oxygen species formation in peripheral blood neutrophils in different types of smokers. Indian J. Med. Res. 106:1997;475-480.
38. Lee V., Randhawa A.K., Singal P.K. Adriamycin-induced myocardial dysfunction in vitro is mediated by free radicals. Am. J. Physiol. 261:1991;H985-H995.
39. Rao G.S. Glutathionyl hydroquinone: a potent pro-oxidant and a possible toxic metabolite of benzene. Toxicology. 8:1996;49-54.
40. Harapanhalli R.S., Yaghmai V., Giuliani D., Howell R.W., Rao D.V. Antioxidant effects of vitamin C in mice following X-irradiation. Res. Commun. Mol. Pathol. 94:1996;271-287.
41. Anderson D., Basaran N., Blowers S.D., Edwards A.J. The effect of antioxidants on bleomycin treatment in in vitro and in vivo genotoxicity assays. Mutat. Res. 329:1995;37-47.
42. Tan D.-X., Manchester L.C., Reiter R.J., Plummer B.J., Hardies L.J., Weintraub S.T., Vijayalaxmi. Shepherd, a novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation. Biochem. Biophys. Res. Commun. 253:1998;614-620.
43. Sewerynek E., Ortiz G.G., Reiter R.J., Pablos M.I., Melchiorri D., Daniels W.M.U. Lipopolysaccharide-induced DNA damage is greatly reduced in rats treated with the pineal hormone melatonin. Mol. Cell. Endocrinol. 117:1996;183-188.
44. Rapozzi V., Zorzet S., Comelli M., Mavelli I., Perissin L., Giraldi T. Melatonin decreases bone marrow and lymphatic toxicity of adriamycin in mice bearing TLX5 lymphoma. Life Sci. 19:1998;1701-1713.
45. Maestroni G.J. Kappa-opioid receptors in marrow stroma mediate the hematopoietic effects of melatonin-induced opioid cytokines. Ann. New York Acad. Sci. 840:1998;411-419.
46. Maestroni G.J. T-helper-2 lymphocytes as a peripheral target of melatonin. J. Pineal Res. 18:1995;84-89.
47. Reiter R.J., Maestroni G.J.M. Melatonin in relation to the antioxidative defense and immune system: possible implications for cell and organ transplantation. J. Mol. Med. 77:1999;36-39.