Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-β1-42

Journal of Pineal Research

Volumn 45, Issue 2, 2008, Pages 157-165

  Zhou, Juefei ^a,b   Zhang, Shen ^c   Zhao, Xingyu ^a,b   Wei, Taotao ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c HUAIHUA MEDICAL COLLEGE   (China)

Author keywords

Alzheimer's disease; Amyloid ; Melatonin; Microglia; NADPH oxidase; Superoxide anion

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; MELATONIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P47; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; INCUBATION TIME; INHIBITION KINETICS; MICROGLIA; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; BLOTTING, WESTERN; CELL MEMBRANE; CELLS, CULTURED; ELECTRON SPIN RESONANCE SPECTROSCOPY; IMMUNOPRECIPITATION; MELATONIN; MICROGLIA; NADPH OXIDASE; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 49549092451     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2008.00570.x     Document Type: Article

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