CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 Checkpoint

Cancer Research

Volumn 74, Issue 14, 2014, Pages 3880-3889

  Hirokawa, Takahisa ^a   Shiotani, Bunsyo ^b   Shimada, Midori ^a   Murata, Kazuhiro ^a   Johmura, Yoshikazu ^a   Haruta, Mayumi ^a   Tahara, Hidetoshi ^b   Takeyama, Hiromitsu ^a   Nakanishi, Makoto ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ATR PROTEIN; CBP 93872; NIBRIN; PROTEIN P53; REPLICATION FACTOR A; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DRUG MECHANISM; DRUG STRUCTURE; G2 PHASE CELL CYCLE CHECKPOINT; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANILINE COMPOUNDS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROPANOLAMINES; PROTEIN BINDING;

EID: 84904248535     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3604     Document Type: Article

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