-
1
-
-
0037184909
-
Taking the study of cancer cell survival to a new dimension
-
Jacks T, Weinberg RA. Taking the study of cancer cell survival to a new dimension. Cell 2002, 111:923-925.
-
(2002)
Cell
, vol.111
, pp. 923-925
-
-
Jacks, T.1
Weinberg, R.A.2
-
2
-
-
0032970945
-
Three-dimensional spheroid model in tumor biology
-
Santini MT, Rainaldi G. Three-dimensional spheroid model in tumor biology. Pathobiology 1999, 67:148-157.
-
(1999)
Pathobiology
, vol.67
, pp. 148-157
-
-
Santini, M.T.1
Rainaldi, G.2
-
3
-
-
0024281372
-
Cell and environment interactions in tumor microregions: the multicell spheroid model
-
Sutherland RM. Cell and environment interactions in tumor microregions: the multicell spheroid model. Science 1988, 240:177-184.
-
(1988)
Science
, vol.240
, pp. 177-184
-
-
Sutherland, R.M.1
-
4
-
-
0037167843
-
Cell biology: survival in three dimensions
-
Yamada KM, Clark K. Cell biology: survival in three dimensions. Nature 2002, 419:790-791.
-
(2002)
Nature
, vol.419
, pp. 790-791
-
-
Yamada, K.M.1
Clark, K.2
-
5
-
-
84866251102
-
Advances in the formation, use and understanding of multi-cellular spheroids
-
Achilli TM, Meyer J, Morgan JR. Advances in the formation, use and understanding of multi-cellular spheroids. Expert opinion on biological therapy 2012, 12:1347-1360.
-
(2012)
Expert opinion on biological therapy
, vol.12
, pp. 1347-1360
-
-
Achilli, T.M.1
Meyer, J.2
Morgan, J.R.3
-
6
-
-
0035090596
-
Chromatofocusing nonporous reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of proteins from human breast cancer whole cell lysates: a novel two-dimensional liquid chromatography/mass spectrometry method
-
Chong BE, Yan F, Lubman DM, Miller FR. Chromatofocusing nonporous reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of proteins from human breast cancer whole cell lysates: a novel two-dimensional liquid chromatography/mass spectrometry method. Rapid Commun Mass Spectrom 2001, 15:291-296.
-
(2001)
Rapid Commun Mass Spectrom
, vol.15
, pp. 291-296
-
-
Chong, B.E.1
Yan, F.2
Lubman, D.M.3
Miller, F.R.4
-
7
-
-
84865453325
-
The multicellular tumor spheroid model for high-throughput cancer drug discovery
-
Labarbera DV, Reid BG, Yoo BH. The multicellular tumor spheroid model for high-throughput cancer drug discovery. Expert opinion on drug discovery 2012, 7:819-30.
-
(2012)
Expert opinion on drug discovery
, vol.7
, pp. 819-830
-
-
Labarbera, D.V.1
Reid, B.G.2
Yoo, B.H.3
-
8
-
-
0023093713
-
Multicellular spheroids: A review on cellular aggregates in cancer research
-
Mueller-Klieser W. Multicellular spheroids: A review on cellular aggregates in cancer research. J Cancer Res Clin Oncol 1987, 113:101-122.
-
(1987)
J Cancer Res Clin Oncol
, vol.113
, pp. 101-122
-
-
Mueller-Klieser, W.1
-
9
-
-
0021670129
-
Growth and cellular characteristics of multicell spheroids
-
Sutherland RM, Durand RE. Growth and cellular characteristics of multicell spheroids. Recent Result Cancer Res 1984, 95:24-49.
-
(1984)
Recent Result Cancer Res
, vol.95
, pp. 24-49
-
-
Sutherland, R.M.1
Durand, R.E.2
-
10
-
-
77951975325
-
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
-
Vermeulen L, De Sousa EMF, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol 2010, 12:468-476.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 468-476
-
-
Vermeulen, L.1
De Sousa, E.M.F.2
van der Heijden, M.3
Cameron, K.4
de Jong, J.H.5
Borovski, T.6
Tuynman, J.B.7
Todaro, M.8
Merz, C.9
Rodermond, H.10
Sprick, M.R.11
Kemper, K.12
Richel, D.J.13
Stassi, G.14
Medema, J.P.15
-
11
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133:704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
12
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 2007, 449:1003-1007.
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
van Es, J.H.2
Kuipers, J.3
Kujala, P.4
van den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
Clevers, H.11
-
13
-
-
84897022044
-
Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging
-
Ritsma L, Ellenbroek SI, Zomer A, Snippert HJ, de Sauvage FJ, Simons BD, Clevers H, van Rheenen J. Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging. Nature 2014, 507:362-365.
-
(2014)
Nature
, vol.507
, pp. 362-365
-
-
Ritsma, L.1
Ellenbroek, S.I.2
Zomer, A.3
Snippert, H.J.4
de Sauvage, F.J.5
Simons, B.D.6
Clevers, H.7
van Rheenen, J.8
-
14
-
-
84878760040
-
Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications
-
Sato T, Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 2013, 340:1190-1194.
-
(2013)
Science
, vol.340
, pp. 1190-1194
-
-
Sato, T.1
Clevers, H.2
-
15
-
-
79953067218
-
In vitro production of functional sperm in cultured neonatal mouse testes
-
Sato T, Katagiri K, Gohbara A, Inoue K, Ogonuki N, Ogura A, Kubota Y, Ogawa T. In vitro production of functional sperm in cultured neonatal mouse testes. Nature 2011, 471:504-507.
-
(2011)
Nature
, vol.471
, pp. 504-507
-
-
Sato, T.1
Katagiri, K.2
Gohbara, A.3
Inoue, K.4
Ogonuki, N.5
Ogura, A.6
Kubota, Y.7
Ogawa, T.8
-
16
-
-
84857491952
-
Colorectal cancer stem cells
-
Vaiopoulos AG, Kostakis ID, Koutsilieris M, Papavassiliou AG. Colorectal cancer stem cells. Stem Cells 2012, 30:363-371.
-
(2012)
Stem Cells
, vol.30
, pp. 363-371
-
-
Vaiopoulos, A.G.1
Kostakis, I.D.2
Koutsilieris, M.3
Papavassiliou, A.G.4
-
17
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci U S A 2007, 104:10158-10163.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, C.13
Clarke, M.F.14
-
18
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007, 445:106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
19
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R. Identification and expansion of human colon-cancer-initiating cells. Nature 2007, 445:111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
20
-
-
84864131103
-
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+ 4' cell markers
-
Munoz J, Stange DE, Schepers AG, van de Wetering M, Koo BK, Itzkovitz S, Volckmann R, Kung KS, Koster J, Radulescu S, Myant K, Versteeg R, Sansom OJ, van Es JH, Barker N, van Oudenaarden A, Mohammed S, Heck AJ, Clevers H. The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+ 4' cell markers. EMBO J 2012, 31:3079-3091.
-
(2012)
EMBO J
, vol.31
, pp. 3079-3091
-
-
Munoz, J.1
Stange, D.E.2
Schepers, A.G.3
van de Wetering, M.4
Koo, B.K.5
Itzkovitz, S.6
Volckmann, R.7
Kung, K.S.8
Koster, J.9
Radulescu, S.10
Myant, K.11
Versteeg, R.12
Sansom, O.J.13
van Es, J.H.14
Barker, N.15
van Oudenaarden, A.16
Mohammed, S.17
Heck, A.J.18
Clevers, H.19
-
21
-
-
44049091352
-
Cancer stem cells-old concepts, new insights
-
Vermeulen L, Sprick MR, Kemper K, Stassi G, Medema JP. Cancer stem cells-old concepts, new insights. Cell Death Differ 2008, 15:947-958.
-
(2008)
Cell Death Differ
, vol.15
, pp. 947-958
-
-
Vermeulen, L.1
Sprick, M.R.2
Kemper, K.3
Stassi, G.4
Medema, J.P.5
-
22
-
-
41349089501
-
The new look of colorectal cancer stem cells
-
Lassmann S, Opitz OG. The new look of colorectal cancer stem cells. Gastroenterology 2008, 134:1262-1264.
-
(2008)
Gastroenterology
, vol.134
, pp. 1262-1264
-
-
Lassmann, S.1
Opitz, O.G.2
-
23
-
-
79960007999
-
Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan
-
Emmink BL, Van Houdt WJ, Vries RG, Hoogwater FJ, Govaert KM, Verheem A, Nijkamp MW, Steller EJ, Jimenez CR, Clevers H, Borel Rinkes IH, Kranenburg O. Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan. Gastroenterology 2011, 141:269-278.
-
(2011)
Gastroenterology
, vol.141
, pp. 269-278
-
-
Emmink, B.L.1
Van Houdt, W.J.2
Vries, R.G.3
Hoogwater, F.J.4
Govaert, K.M.5
Verheem, A.6
Nijkamp, M.W.7
Steller, E.J.8
Jimenez, C.R.9
Clevers, H.10
Borel Rinkes, I.H.11
Kranenburg, O.12
-
24
-
-
37049019888
-
Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens
-
Naiki-Ito A, Asamoto M, Hokaiwado N, Takahashi S, Yamashita H, Tsuda H, Ogawa K, Shirai T. Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens. Cancer Res 2007, 67:11353-11358.
-
(2007)
Cancer Res
, vol.67
, pp. 11353-11358
-
-
Naiki-Ito, A.1
Asamoto, M.2
Hokaiwado, N.3
Takahashi, S.4
Yamashita, H.5
Tsuda, H.6
Ogawa, K.7
Shirai, T.8
-
25
-
-
38749134864
-
A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells
-
Espina C, Cespedes MV, Garcia-Cabezas MA, del Pulgar MT G, Boluda A, Oroz LG, Benitah SA, Cejas P, Nistal M, Mangues R, Lacal JC. A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells. Am J Pathol 2008, 172:156-166.
-
(2008)
Am J Pathol
, vol.172
, pp. 156-166
-
-
Espina, C.1
Cespedes, M.V.2
Garcia-Cabezas, M.A.3
del Pulgar MT, G.4
Boluda, A.5
Oroz, L.G.6
Benitah, S.A.7
Cejas, P.8
Nistal, M.9
Mangues, R.10
Lacal, J.C.11
-
26
-
-
33847740988
-
Wnt/beta-catenin signaling in cancer stemness and malignant behavior
-
Fodde R, Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol 2007, 19:150-158.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 150-158
-
-
Fodde, R.1
Brabletz, T.2
-
27
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005, 434:843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
28
-
-
0025392973
-
Multicellular tumor spheroids from human gliomas maintained in organ culture
-
Bjerkvig R, Tonnesen A, Laerum OD, Backlund EO. Multicellular tumor spheroids from human gliomas maintained in organ culture. J Neurosurg 1990, 72:463-475.
-
(1990)
J Neurosurg
, vol.72
, pp. 463-475
-
-
Bjerkvig, R.1
Tonnesen, A.2
Laerum, O.D.3
Backlund, E.O.4
-
29
-
-
0032899385
-
Growth of precultured human glioma specimens in nude rat brain
-
Engebraaten O, Hjortland GO, Hirschberg H, Fodstad O. Growth of precultured human glioma specimens in nude rat brain. J Neurosurg 1999, 90:125-132.
-
(1999)
J Neurosurg
, vol.90
, pp. 125-132
-
-
Engebraaten, O.1
Hjortland, G.O.2
Hirschberg, H.3
Fodstad, O.4
-
30
-
-
33644874969
-
Combined modality therapy of gemcitabine and irradiation on human glioma spheroids derived from cell lines and biopsy tissue
-
Fehlauer F, Muench M, Smid EJ, Slotman B, Richter E, Van der Valk P, Sminia P. Combined modality therapy of gemcitabine and irradiation on human glioma spheroids derived from cell lines and biopsy tissue. Oncol Rep 2006, 15:97-105.
-
(2006)
Oncol Rep
, vol.15
, pp. 97-105
-
-
Fehlauer, F.1
Muench, M.2
Smid, E.J.3
Slotman, B.4
Richter, E.5
Van der Valk, P.6
Sminia, P.7
-
31
-
-
0029025306
-
Tumour fragment spheroids from human non-small-cell lung cancer maintained in organ culture
-
Fjellbirkeland L, Bjerkvig R, Laerum OD. Tumour fragment spheroids from human non-small-cell lung cancer maintained in organ culture. Virchows Arch 1995, 426:169-178.
-
(1995)
Virchows Arch
, vol.426
, pp. 169-178
-
-
Fjellbirkeland, L.1
Bjerkvig, R.2
Laerum, O.D.3
-
32
-
-
68149166750
-
Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness
-
Weiswald LB, Richon S, Validire P, Briffod M, Lai-Kuen R, Cordelieres FP, Bertrand F, Dargere D, Massonnet G, Marangoni E, Gayet B, Pocard M, Bieche I, Poupon MF, Bellet D, Dangles-Marie V. Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness. Br J Cancer 2009, 101:473-482.
-
(2009)
Br J Cancer
, vol.101
, pp. 473-482
-
-
Weiswald, L.B.1
Richon, S.2
Validire, P.3
Briffod, M.4
Lai-Kuen, R.5
Cordelieres, F.P.6
Bertrand, F.7
Dargere, D.8
Massonnet, G.9
Marangoni, E.10
Gayet, B.11
Pocard, M.12
Bieche, I.13
Poupon, M.F.14
Bellet, D.15
Dangles-Marie, V.16
-
33
-
-
33750814849
-
Angiogenesis-independent tumor growth mediated by stem-like cancer cells
-
Sakariassen PO, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Oyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PO. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A 2006, 103:16466-16471.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16466-16471
-
-
Sakariassen, P.O.1
Prestegarden, L.2
Wang, J.3
Skaftnesmo, K.O.4
Mahesparan, R.5
Molthoff, C.6
Sminia, P.7
Sundlisaeter, E.8
Misra, A.9
Tysnes, B.B.10
Chekenya, M.11
Peters, H.12
Lende, G.13
Kalland, K.H.14
Oyan, A.M.15
Petersen, K.16
Jonassen, I.17
van der Kogel, A.18
Feuerstein, B.G.19
Terzis, A.J.20
Bjerkvig, R.21
Enger, P.O.22
more..
-
34
-
-
84864264964
-
Proteomics in studying cancer stem cell biology
-
Kranenburg O, Emmink BL, Knol J, van Houdt WJ, Rinkes IH, Jimenez CR. Proteomics in studying cancer stem cell biology. Expert Rev Proteomics 2012, 9:325-336.
-
(2012)
Expert Rev Proteomics
, vol.9
, pp. 325-336
-
-
Kranenburg, O.1
Emmink, B.L.2
Knol, J.3
van Houdt, W.J.4
Rinkes, I.H.5
Jimenez, C.R.6
-
35
-
-
80054857419
-
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium
-
Sato T, Stange DE, Ferrante M, Vries RG, Van Es JH, Van den Brink S, Van Houdt WJ, Pronk A, Van Gorp J, Siersema PD, Clevers H. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology 2011, 141:1762-1772.
-
(2011)
Gastroenterology
, vol.141
, pp. 1762-1772
-
-
Sato, T.1
Stange, D.E.2
Ferrante, M.3
Vries, R.G.4
Van Es, J.H.5
Van den Brink, S.6
Van Houdt, W.J.7
Pronk, A.8
Van Gorp, J.9
Siersema, P.D.10
Clevers, H.11
-
36
-
-
41149163821
-
The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids
-
De Witt Hamer PC, Van Tilborg AA, Eijk PP, Sminia P, Troost D, Van Noorden CJ, Ylstra B, Leenstra S. The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids. Oncogene 2008, 27:2091-2096.
-
(2008)
Oncogene
, vol.27
, pp. 2091-2096
-
-
De Witt Hamer, P.C.1
Van Tilborg, A.A.2
Eijk, P.P.3
Sminia, P.4
Troost, D.5
Van Noorden, C.J.6
Ylstra, B.7
Leenstra, S.8
-
37
-
-
73049116186
-
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 2010, 6:25-36.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
Huch, M.2
Kujala, P.3
van de Wetering, M.4
Snippert, H.J.5
van Es, J.H.6
Sato, T.7
Stange, D.E.8
Begthel, H.9
van den Born, M.10
Danenberg, E.11
van den Brink, S.12
Korving, J.13
Abo, A.14
Peters, P.J.15
Wright, N.16
Poulsom, R.17
Clevers, H.18
-
38
-
-
84873712443
-
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
-
Huch M, Dorrell C, Boj SF, van Es JH, Li VS, van de Wetering M, Sato T, Hamer K, Sasaki N, Finegold MJ, Haft A, Vries RG, Grompe M, Clevers H. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature 2013, 494:247-250.
-
(2013)
Nature
, vol.494
, pp. 247-250
-
-
Huch, M.1
Dorrell, C.2
Boj, S.F.3
van Es, J.H.4
Li, V.S.5
van de Wetering, M.6
Sato, T.7
Hamer, K.8
Sasaki, N.9
Finegold, M.J.10
Haft, A.11
Vries, R.G.12
Grompe, M.13
Clevers, H.14
-
39
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
-
Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009, 459:262-265.
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
Vries, R.G.2
Snippert, H.J.3
van de Wetering, M.4
Barker, N.5
Stange, D.E.6
van Es, J.H.7
Abo, A.8
Kujala, P.9
Peters, P.J.10
Clevers, H.11
-
40
-
-
33750479526
-
The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia
-
Blaydon DC, Ishii Y, O'Toole EA, Unsworth HC, Teh MT, Ruschendorf F, Sinclair C, Hopsu-Havu VK, Tidman N, Moss C, Watson R, de Berker D, Wajid M, Christiano AM, Kelsell DP. The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia. Nat Genet 2006, 38:1245-1247.
-
(2006)
Nat Genet
, vol.38
, pp. 1245-1247
-
-
Blaydon, D.C.1
Ishii, Y.2
O'Toole, E.A.3
Unsworth, H.C.4
Teh, M.T.5
Ruschendorf, F.6
Sinclair, C.7
Hopsu-Havu, V.K.8
Tidman, N.9
Moss, C.10
Watson, R.11
de Berker, D.12
Wajid, M.13
Christiano, A.M.14
Kelsell, D.P.15
-
41
-
-
79960990066
-
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling
-
Carmon KS, Gong X, Lin Q, Thomas A, Liu Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A 2011, 108:11452-11457.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11452-11457
-
-
Carmon, K.S.1
Gong, X.2
Lin, Q.3
Thomas, A.4
Liu, Q.5
-
42
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
de Lau W, Barker N, Low TY, Koo BK, Li VS, Teunissen H, Kujala P, Haegebarth A, Peters PJ, van de Wetering M, Stange DE, van Es JE, Guardavaccaro D, Schasfoort RB, Mohri Y, Nishimori K, Mohammed S, Heck AJ, Clevers H. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 2011, 476:293-297.
-
(2011)
Nature
, vol.476
, pp. 293-297
-
-
de Lau, W.1
Barker, N.2
Low, T.Y.3
Koo, B.K.4
Li, V.S.5
Teunissen, H.6
Kujala, P.7
Haegebarth, A.8
Peters, P.J.9
van de Wetering, M.10
Stange, D.E.11
van Es, J.E.12
Guardavaccaro, D.13
Schasfoort, R.B.14
Mohri, Y.15
Nishimori, K.16
Mohammed, S.17
Heck, A.J.18
Clevers, H.19
-
43
-
-
23844455584
-
Mitogenic influence of human R-spondin1 on the intestinal epithelium
-
Kim KA, Kakitani M, Zhao J, Oshima T, Tang T, Binnerts M, Liu Y, Boyle B, Park E, Emtage P, Funk WD, Tomizuka K. Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science 2005, 309:1256-1259.
-
(2005)
Science
, vol.309
, pp. 1256-1259
-
-
Kim, K.A.1
Kakitani, M.2
Zhao, J.3
Oshima, T.4
Tang, T.5
Binnerts, M.6
Liu, Y.7
Boyle, B.8
Park, E.9
Emtage, P.10
Funk, W.D.11
Tomizuka, K.12
-
44
-
-
77951785241
-
Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression
-
Albrethsen J, Knol JC, Piersma SR, Pham TV, de Wit M, Mongera S, Carvalho B, Verheul HM, Fijneman RJ, Meijer GA, Jimenez CR. Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression. Mol Cell Proteomics 2010, 9:988-1005.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 988-1005
-
-
Albrethsen, J.1
Knol, J.C.2
Piersma, S.R.3
Pham, T.V.4
de Wit, M.5
Mongera, S.6
Carvalho, B.7
Verheul, H.M.8
Fijneman, R.J.9
Meijer, G.A.10
Jimenez, C.R.11
-
45
-
-
77950641486
-
Workflow comparison for label-free, quantitative secretome proteomics for cancer biomarker discovery: method evaluation, differential analysis, and verification in serum
-
Piersma SR, Fiedler U, Span S, Lingnau A, Pham TV, Hoffmann S, Kubbutat MH, Jimenez CR. Workflow comparison for label-free, quantitative secretome proteomics for cancer biomarker discovery: method evaluation, differential analysis, and verification in serum. J Proteome Res 2010, 9:1913-1922.
-
(2010)
J Proteome Res
, vol.9
, pp. 1913-1922
-
-
Piersma, S.R.1
Fiedler, U.2
Span, S.3
Lingnau, A.4
Pham, T.V.5
Hoffmann, S.6
Kubbutat, M.H.7
Jimenez, C.R.8
-
46
-
-
84875992472
-
Secreted heat shock protein 90alpha (HSP90alpha) induces nuclear factor-kappaB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion
-
Chen WS, Chen CC, Chen LL, Lee CC, Huang TS. Secreted heat shock protein 90alpha (HSP90alpha) induces nuclear factor-kappaB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion. J Biol Chem 2013, 288:9001-9010.
-
(2013)
J Biol Chem
, vol.288
, pp. 9001-9010
-
-
Chen, W.S.1
Chen, C.C.2
Chen, L.L.3
Lee, C.C.4
Huang, T.S.5
-
47
-
-
78651324347
-
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
-
Szklarczyk D, Franceschini A, Kuhn M, Simonovic M, Roth A, Minguez P, Doerks T, Stark M, Muller J, Bork P, Jensen LJ, von Mering C. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res 2011, 39:D561-568.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Szklarczyk, D.1
Franceschini, A.2
Kuhn, M.3
Simonovic, M.4
Roth, A.5
Minguez, P.6
Doerks, T.7
Stark, M.8
Muller, J.9
Bork, P.10
Jensen, L.J.11
von Mering, C.12
-
48
-
-
79551587720
-
Cytoscape 2.8: new features for data integration and network visualization
-
Smoot ME, Ono K, Ruscheinski J, Wang PL, Ideker T. Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics 2011, 27:431-432.
-
(2011)
Bioinformatics
, vol.27
, pp. 431-432
-
-
Smoot, M.E.1
Ono, K.2
Ruscheinski, J.3
Wang, P.L.4
Ideker, T.5
-
49
-
-
24044440971
-
BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
-
Maere S, Heymans K, Kuiper M. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 2005, 21:3448-3449.
-
(2005)
Bioinformatics
, vol.21
, pp. 3448-3449
-
-
Maere, S.1
Heymans, K.2
Kuiper, M.3
-
50
-
-
4644306516
-
A distinct " side population" of cells with high drug efflux capacity in human tumor cells
-
Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. A distinct " side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A 2004, 101:14228-14233.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.E.2
Wulf, G.G.3
Nuchtern, J.G.4
Jax, T.W.5
Gobel, U.6
Goodell, M.A.7
Brenner, M.K.8
-
51
-
-
33744535197
-
Telomeres and telomerase in cancer stem cells
-
Ju Z, Rudolph KL. Telomeres and telomerase in cancer stem cells. Eur J Cancer 2006, 42:1197-1203.
-
(2006)
Eur J Cancer
, vol.42
, pp. 1197-1203
-
-
Ju, Z.1
Rudolph, K.L.2
-
52
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, Bronner-Fraser M, Kornblum HI. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A 2003, 100:15178-15183.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
Masterman-Smith, M.4
Geschwind, D.H.5
Bronner-Fraser, M.6
Kornblum, H.I.7
-
53
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003, 63:5821-5828.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
54
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Identification of human brain tumour initiating cells. Nature 2004, 432:396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
55
-
-
11244293572
-
Isolation of cancer stem cells from adult glioblastoma multiforme
-
Yuan X, Curtin J, Xiong Y, Liu G, Waschsmann-Hogiu S, Farkas DL, Black KL, Yu JS. Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 2004, 23:9392-9400.
-
(2004)
Oncogene
, vol.23
, pp. 9392-9400
-
-
Yuan, X.1
Curtin, J.2
Xiong, Y.3
Liu, G.4
Waschsmann-Hogiu, S.5
Farkas, D.L.6
Black, K.L.7
Yu, J.S.8
-
56
-
-
78651298061
-
Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload
-
Kuipers MA, Stasevich TJ, Sasaki T, Wilson KA, Hazelwood KL, McNally JG, Davidson MW, Gilbert DM. Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload. J Cell Biol 2011, 192:29-41.
-
(2011)
J Cell Biol
, vol.192
, pp. 29-41
-
-
Kuipers, M.A.1
Stasevich, T.J.2
Sasaki, T.3
Wilson, K.A.4
Hazelwood, K.L.5
McNally, J.G.6
Davidson, M.W.7
Gilbert, D.M.8
-
57
-
-
34249066085
-
PCNA, the maestro of the replication fork
-
Moldovan GL, Pfander B, Jentsch S. PCNA, the maestro of the replication fork. Cell 2007, 129:665-679.
-
(2007)
Cell
, vol.129
, pp. 665-679
-
-
Moldovan, G.L.1
Pfander, B.2
Jentsch, S.3
-
59
-
-
77957662160
-
Heterochromatin protein 1 (HP1) connects the FACT histone chaperone complex to the phosphorylated CTD of RNA polymerase II
-
Kwon SH, Florens L, Swanson SK, Washburn MP, Abmayr SM, Workman JL. Heterochromatin protein 1 (HP1) connects the FACT histone chaperone complex to the phosphorylated CTD of RNA polymerase II. Genes Dev 2010, 24:2133-2145.
-
(2010)
Genes Dev
, vol.24
, pp. 2133-2145
-
-
Kwon, S.H.1
Florens, L.2
Swanson, S.K.3
Washburn, M.P.4
Abmayr, S.M.5
Workman, J.L.6
-
60
-
-
23044431656
-
Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin
-
Vakoc CR, Mandat SA, Olenchock BA, Blobel GA. Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell 2005, 19:381-391.
-
(2005)
Mol Cell
, vol.19
, pp. 381-391
-
-
Vakoc, C.R.1
Mandat, S.A.2
Olenchock, B.A.3
Blobel, G.A.4
-
62
-
-
0036299092
-
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly
-
Ahmad K, Henikoff S. The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell 2002, 9:1191-1200.
-
(2002)
Mol Cell
, vol.9
, pp. 1191-1200
-
-
Ahmad, K.1
Henikoff, S.2
-
63
-
-
77956409475
-
Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3
-
Santenard A, Ziegler-Birling C, Koch M, Tora L, Bannister AJ, Torres-Padilla ME. Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3. Nat Cell Biol 2010, 12:853-862.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 853-862
-
-
Santenard, A.1
Ziegler-Birling, C.2
Koch, M.3
Tora, L.4
Bannister, A.J.5
Torres-Padilla, M.E.6
-
64
-
-
77952917994
-
Chromatin environment of histone variant H3.3 revealed by quantitative imaging and genome-scale chromatin and DNA immunoprecipitation
-
Delbarre E, Jacobsen BM, Reiner AH, Sorensen AL, Kuntziger T, Collas P. Chromatin environment of histone variant H3.3 revealed by quantitative imaging and genome-scale chromatin and DNA immunoprecipitation. Mol Biol Cell 2010, 21:1872-1884.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1872-1884
-
-
Delbarre, E.1
Jacobsen, B.M.2
Reiner, A.H.3
Sorensen, A.L.4
Kuntziger, T.5
Collas, P.6
-
66
-
-
0035846894
-
Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein
-
Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D. Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell 2001, 104:119-130.
-
(2001)
Cell
, vol.104
, pp. 119-130
-
-
Seo, S.B.1
McNamara, P.2
Heo, S.3
Turner, A.4
Lane, W.S.5
Chakravarti, D.6
-
67
-
-
0037067661
-
The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing
-
Cervoni N, Detich N, Seo SB, Chakravarti D, Szyf M. The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing. J Biol Chem 2002, 277:25026-25031.
-
(2002)
J Biol Chem
, vol.277
, pp. 25026-25031
-
-
Cervoni, N.1
Detich, N.2
Seo, S.B.3
Chakravarti, D.4
Szyf, M.5
-
68
-
-
77956648852
-
The roles of PARP1 in gene control and cell differentiation
-
Ji Y, Tulin AV. The roles of PARP1 in gene control and cell differentiation. Curr Opin Genet Dev 2010, 20:512-518.
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 512-518
-
-
Ji, Y.1
Tulin, A.V.2
-
69
-
-
67649333085
-
DeubiKuitylation: a novel DUB enzymatic activity for the DNA repair protein, Ku70
-
Rathaus M, Lerrer B, Cohen HY. DeubiKuitylation: a novel DUB enzymatic activity for the DNA repair protein, Ku70. Cell Cycle 2009, 8:1843-1852.
-
(2009)
Cell Cycle
, vol.8
, pp. 1843-1852
-
-
Rathaus, M.1
Lerrer, B.2
Cohen, H.Y.3
-
70
-
-
10944227347
-
NAD + -dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
-
Kim MY, Mauro S, Gevry N, Lis JT, Kraus WL. NAD + -dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell 2004, 119:803-814.
-
(2004)
Cell
, vol.119
, pp. 803-814
-
-
Kim, M.Y.1
Mauro, S.2
Gevry, N.3
Lis, J.T.4
Kraus, W.L.5
-
71
-
-
38449088040
-
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases
-
Hassa PO, Hottiger MO. The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. Front Biosci 2008, 13:3046-3082.
-
(2008)
Front Biosci
, vol.13
, pp. 3046-3082
-
-
Hassa, P.O.1
Hottiger, M.O.2
-
72
-
-
83055168538
-
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target
-
Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target. Mol Cell Proteomics 2011, 10:M111 011353.
-
(2011)
Mol Cell Proteomics
, vol.10
-
-
Van Houdt, W.J.1
Emmink, B.L.2
Pham, T.V.3
Piersma, S.R.4
Verheem, A.5
Vries, R.G.6
Fratantoni, S.A.7
Pronk, A.8
Clevers, H.9
Borel Rinkes, I.H.10
Jimenez, C.R.11
Kranenburg, O.12
-
73
-
-
58149356243
-
Confirmation of gene expression-based prediction of survival in non-small cell lung cancer
-
Guo NL, Wan YW, Tosun K, Lin H, Msiska Z, Flynn DC, Remick SC, Vallyathan V, Dowlati A, Shi X, Castranova V, Beer DG, Qian Y. Confirmation of gene expression-based prediction of survival in non-small cell lung cancer. Clin Cancer Res 2008, 14:8213-8220.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8213-8220
-
-
Guo, N.L.1
Wan, Y.W.2
Tosun, K.3
Lin, H.4
Msiska, Z.5
Flynn, D.C.6
Remick, S.C.7
Vallyathan, V.8
Dowlati, A.9
Shi, X.10
Castranova, V.11
Beer, D.G.12
Qian, Y.13
-
74
-
-
33645221975
-
Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance
-
Cleator S, Tsimelzon A, Ashworth A, Dowsett M, Dexter T, Powles T, Hilsenbeck S, Wong H, Osborne CK, O'Connell P, Chang JC. Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance. Breast Cancer Res Treat 2006, 95:229-233.
-
(2006)
Breast Cancer Res Treat
, vol.95
, pp. 229-233
-
-
Cleator, S.1
Tsimelzon, A.2
Ashworth, A.3
Dowsett, M.4
Dexter, T.5
Powles, T.6
Hilsenbeck, S.7
Wong, H.8
Osborne, C.K.9
O'Connell, P.10
Chang, J.C.11
-
75
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
76
-
-
44449147036
-
Tumor cell metabolism: cancer's Achilles' heel
-
Kroemer G, Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 2008, 13:472-482.
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
78
-
-
84861964103
-
New aspects of the Warburg effect in cancer cell biology
-
Bensinger SJ, Christofk HR. New aspects of the Warburg effect in cancer cell biology. Semin Cell Dev Biol 2012, 23:352-361.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 352-361
-
-
Bensinger, S.J.1
Christofk, H.R.2
-
79
-
-
79960697705
-
Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells
-
Yang H, Dou Y, Zheng X, Tan Y, Cheng J, Li L, Du Y, Zhu D, Lou Y. Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells. Toxicology 2011, 287:38-45.
-
(2011)
Toxicology
, vol.287
, pp. 38-45
-
-
Yang, H.1
Dou, Y.2
Zheng, X.3
Tan, Y.4
Cheng, J.5
Li, L.6
Du, Y.7
Zhu, D.8
Lou, Y.9
-
80
-
-
67651202156
-
Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination
-
Krasnikov BF, Chien CH, Nostramo R, Pinto JT, Nieves E, Callaway M, Sun J, Huebner K, Cooper AJ. Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination. Biochimie 2009, 91:1072-1080.
-
(2009)
Biochimie
, vol.91
, pp. 1072-1080
-
-
Krasnikov, B.F.1
Chien, C.H.2
Nostramo, R.3
Pinto, J.T.4
Nieves, E.5
Callaway, M.6
Sun, J.7
Huebner, K.8
Cooper, A.J.9
-
81
-
-
0025611278
-
The enzymes of detoxication
-
Jakoby WB, Ziegler DM. The enzymes of detoxication. J Biol Chem 1990, 265:20715-20718.
-
(1990)
J Biol Chem
, vol.265
, pp. 20715-20718
-
-
Jakoby, W.B.1
Ziegler, D.M.2
-
82
-
-
0032006030
-
Human aldehyde dehydrogenase gene family
-
Yoshida A, Rzhetsky A, Hsu LC, Chang C. Human aldehyde dehydrogenase gene family. Eur J Biochem 1998, 251:549-557.
-
(1998)
Eur J Biochem
, vol.251
, pp. 549-557
-
-
Yoshida, A.1
Rzhetsky, A.2
Hsu, L.C.3
Chang, C.4
-
83
-
-
0035827627
-
Targeted inactivation of Gh/tissue transglutaminase II
-
Nanda N, Iismaa SE, Owens WA, Husain A, Mackay F, Graham RM. Targeted inactivation of Gh/tissue transglutaminase II. J Biol Chem 2001, 276:20673-20678.
-
(2001)
J Biol Chem
, vol.276
, pp. 20673-20678
-
-
Nanda, N.1
Iismaa, S.E.2
Owens, W.A.3
Husain, A.4
Mackay, F.5
Graham, R.M.6
-
84
-
-
0033004913
-
Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis
-
Piredda L, Farrace MG, Lo Bello M, Malorni W, Melino G, Petruzzelli R, Piacentini M. Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis. FASEB J 1999, 13:355-364.
-
(1999)
FASEB J
, vol.13
, pp. 355-364
-
-
Piredda, L.1
Farrace, M.G.2
Lo Bello, M.3
Malorni, W.4
Melino, G.5
Petruzzelli, R.6
Piacentini, M.7
-
85
-
-
41149105722
-
Mitochondria in cancer cells: what is so special about them?
-
Gogvadze V, Orrenius S, Zhivotovsky B. Mitochondria in cancer cells: what is so special about them?. Trends Cell Biol 2008, 18:165-173.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 165-173
-
-
Gogvadze, V.1
Orrenius, S.2
Zhivotovsky, B.3
-
86
-
-
84861986053
-
Wnt/beta-Catenin Signaling and Disease
-
Clevers H, Nusse R. Wnt/beta-Catenin Signaling and Disease. Cell 2012, 149:1192-1205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
87
-
-
84861972831
-
Wnt Signaling through Inhibition of beta-Catenin Degradation in an Intact Axin1 Complex
-
Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, Gerlach JP, Mohammed S, Heck AJ, Maurice MM, Mahmoudi T, Clevers H. Wnt Signaling through Inhibition of beta-Catenin Degradation in an Intact Axin1 Complex. Cell 2012, 149:1245-1256.
-
(2012)
Cell
, vol.149
, pp. 1245-1256
-
-
Li, V.S.1
Ng, S.S.2
Boersema, P.J.3
Low, T.Y.4
Karthaus, W.R.5
Gerlach, J.P.6
Mohammed, S.7
Heck, A.J.8
Maurice, M.M.9
Mahmoudi, T.10
Clevers, H.11
-
88
-
-
33847011050
-
Ku70 and poly (ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling
-
Idogawa M, Masutani M, Shitashige M, Honda K, Tokino T, Shinomura Y, Imai K, Hirohashi S, Yamada T. Ku70 and poly (ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling. Cancer Res 2007, 67:911-918.
-
(2007)
Cancer Res
, vol.67
, pp. 911-918
-
-
Idogawa, M.1
Masutani, M.2
Shitashige, M.3
Honda, K.4
Tokino, T.5
Shinomura, Y.6
Imai, K.7
Hirohashi, S.8
Yamada, T.9
-
89
-
-
20444503830
-
Poly (ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex
-
Idogawa M, Yamada T, Honda K, Sato S, Imai K, Hirohashi S. Poly (ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex. Gastroenterology 2005, 128:1919-1936.
-
(2005)
Gastroenterology
, vol.128
, pp. 1919-1936
-
-
Idogawa, M.1
Yamada, T.2
Honda, K.3
Sato, S.4
Imai, K.5
Hirohashi, S.6
-
90
-
-
45749102020
-
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors
-
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S. CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Invest 2008, 118:2111-2120.
-
(2008)
J Clin Invest
, vol.118
, pp. 2111-2120
-
-
Shmelkov, S.V.1
Butler, J.M.2
Hooper, A.T.3
Hormigo, A.4
Kushner, J.5
Milde, T.6
St Clair, R.7
Baljevic, M.8
White, I.9
Jin, D.K.10
Chadburn, A.11
Murphy, A.J.12
Valenzuela, D.M.13
Gale, N.W.14
Thurston, G.15
Yancopoulos, G.D.16
D'Angelica, M.17
Kemeny, N.18
Lyden, D.19
Rafii, S.20
more..
-
91
-
-
76549120193
-
The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
-
Kemper K, Sprick MR, de Bree M, Scopelliti A, Vermeulen L, Hoek M, Zeilstra J, Pals ST, Mehmet H, Stassi G, Medema JP. The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res 2010, 70:719-729.
-
(2010)
Cancer Res
, vol.70
, pp. 719-729
-
-
Kemper, K.1
Sprick, M.R.2
de Bree, M.3
Scopelliti, A.4
Vermeulen, L.5
Hoek, M.6
Zeilstra, J.7
Pals, S.T.8
Mehmet, H.9
Stassi, G.10
Medema, J.P.11
-
92
-
-
44949218553
-
In-gel digestion of proteins for MALDI-MS fingerprint mapping
-
Chapter 16:Unit 16.14. doi:10.1002/0471140864.ps1604s14
-
Jimenez CR, Huang L, Qiu Y, Burlingame AL. In-gel digestion of proteins for MALDI-MS fingerprint mapping. Curr Protoc Protein Sci 2001, Chapter 16:Unit 16.14. doi:10.1002/0471140864.ps1604s14.
-
(2001)
Curr Protoc Protein Sci
-
-
Jimenez, C.R.1
Huang, L.2
Qiu, Y.3
Burlingame, A.L.4
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