-
1
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 2007, 57:43-66
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
2
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 2005, 55:74-108
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 2000, 100:57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
5
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE: The consensus coding sequences of human breast and colorectal cancers. Science 2006, 314:268-274
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
Szabo, S.11
Buckhaults, P.12
Farrell, C.13
Meeh, P.14
Markowitz, S.D.15
Willis, J.16
Dawson, D.17
Willson, J.K.18
Gazdar, A.F.19
Hartigan, J.20
Wu, L.21
Liu, C.22
Parmigiani, G.23
Park, B.H.24
Bachman, K.E.25
Papadopoulos, N.26
Vogelstein, B.27
Kinzler, K.W.28
Velculescu, V.E.29
more..
-
6
-
-
2342418629
-
Rho-family GTPases: It's not only Rac and Rho (and I like it)
-
Wennerberg K, Der CJ: Rho-family GTPases: it's not only Rac and Rho (and I like it). J Cell Sci 2004, 117:1301-1312
-
(2004)
J Cell Sci
, vol.117
, pp. 1301-1312
-
-
Wennerberg, K.1
Der, C.J.2
-
7
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley AJ, Hall A: The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992, 70:389-399
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
8
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A: The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 1992, 70:401-410
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
9
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes CD, Hall A: Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995, 81:53-62
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
10
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A: Rho GTPases in cell biology. Nature 2002, 420:629-635
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
11
-
-
0036570588
-
Role of Rho family GTPases in epithelial morphogenesis
-
Van Aelst L, Symons M: Role of Rho family GTPases in epithelial morphogenesis. Genes Dev 2002, 16:1032-1054
-
(2002)
Genes Dev
, vol.16
, pp. 1032-1054
-
-
Van Aelst, L.1
Symons, M.2
-
12
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T, Gutkind JS: The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995, 81:1137-1146
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
Miki, T.7
Gutkind, J.S.8
-
13
-
-
0031034469
-
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins
-
Perona R, Montaner S, Saniger L, Sanchez-Perez I, Bravo R, Lacal JC: Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. Genes Dev 1997, 11:463-475
-
(1997)
Genes Dev
, vol.11
, pp. 463-475
-
-
Perona, R.1
Montaner, S.2
Saniger, L.3
Sanchez-Perez, I.4
Bravo, R.5
Lacal, J.C.6
-
14
-
-
0037050260
-
Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB
-
Murga C, Zohar M, Teramoto H, Gutkind JS: Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB. Oncogene 2002, 21:207-216
-
(2002)
Oncogene
, vol.21
, pp. 207-216
-
-
Murga, C.1
Zohar, M.2
Teramoto, H.3
Gutkind, J.S.4
-
15
-
-
1542328238
-
Rho GTPases: Potential candidates for anticancer therapy
-
Aznar S, Fernandez-Valeron P, Espina C, Lacal JC: Rho GTPases: potential candidates for anticancer therapy. Cancer Lett 2004, 206:181-191
-
(2004)
Cancer Lett
, vol.206
, pp. 181-191
-
-
Aznar, S.1
Fernandez-Valeron, P.2
Espina, C.3
Lacal, J.C.4
-
16
-
-
21244478650
-
Rho GTPase expression in tumourigenesis: Evidence for a significant link
-
Gómez del Pulgar T, Benitah SA, Valeron PF, Espina C, Lacal JC: Rho GTPase expression in tumourigenesis: evidence for a significant link. Bioessays 2005, 27:602-613
-
(2005)
Bioessays
, vol.27
, pp. 602-613
-
-
Gómez del Pulgar, T.1
Benitah, S.A.2
Valeron, P.F.3
Espina, C.4
Lacal, J.C.5
-
17
-
-
0037139607
-
The role of Rho GTPases in disease development
-
Boettner B, Van Aelst L: The role of Rho GTPases in disease development. Gene 2002, 286:155-174
-
(2002)
Gene
, vol.286
, pp. 155-174
-
-
Boettner, B.1
Van Aelst, L.2
-
18
-
-
0033747214
-
Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways
-
Attoub S, Noe V, Pirola L, Bruyneel E, Chastre E, Mareel M, Wymann MP, Gespach C: Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. FASEB J 2000, 14:2329-2338
-
(2000)
FASEB J
, vol.14
, pp. 2329-2338
-
-
Attoub, S.1
Noe, V.2
Pirola, L.3
Bruyneel, E.4
Chastre, E.5
Mareel, M.6
Wymann, M.P.7
Gespach, C.8
-
19
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
Kawasaki Y, Senda T, Ishidate T, Koyama R, Morishita T, Iwayama Y, Higuchi O, Akiyama T: Asef, a link between the tumor suppressor APC and G-protein signaling. Science 2000, 289:1194-1197
-
(2000)
Science
, vol.289
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
Iwayama, Y.6
Higuchi, O.7
Akiyama, T.8
-
20
-
-
8844264528
-
Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of betacatenin and TCF/LEF-mediated transcriptional activation
-
Esufali S, Bapat B: Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of betacatenin and TCF/LEF-mediated transcriptional activation. Oncogene 2004, 23:8260-8271
-
(2004)
Oncogene
, vol.23
, pp. 8260-8271
-
-
Esufali, S.1
Bapat, B.2
-
21
-
-
33644859051
-
The rac activator Tiam1 is a Wntresponsive gene that modifies intestinal tumor development
-
Malliri A, Rygiel TP, van der Kammen RA, Song JY, Engers R, Hurlstone AF, Clevers H, Collard JG: The rac activator Tiam1 is a Wntresponsive gene that modifies intestinal tumor development. J Biol Chem 2006, 281:543-548
-
(2006)
J Biol Chem
, vol.281
, pp. 543-548
-
-
Malliri, A.1
Rygiel, T.P.2
van der Kammen, R.A.3
Song, J.Y.4
Engers, R.5
Hurlstone, A.F.6
Clevers, H.7
Collard, J.G.8
-
22
-
-
34748830335
-
Differential expression of Rac1 identifies its target genes and its contribution to progression of colorectal cancer
-
Gomez del Pulgar T, Bandres E, Espina C, Valdes-Mora F, Perez-Palacios R, Garcia-Amigot F, Garcia-Foncillas J, Lacal JC: Differential expression of Rac1 identifies its target genes and its contribution to progression of colorectal cancer. Int J Biochem Cell Biol 2007, 39:2289-2302
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 2289-2302
-
-
Gomez del Pulgar, T.1
Bandres, E.2
Espina, C.3
Valdes-Mora, F.4
Perez-Palacios, R.5
Garcia-Amigot, F.6
Garcia-Foncillas, J.7
Lacal, J.C.8
-
23
-
-
34247876271
-
Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites
-
Céspedes MV, Espina C, Garcia-Cabezas MA, Trias M, Boluda A, del Pulgar MT, Sancho FJ, Nistal M, Lacal JC, Mangues R: Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites. Am J Pathol 2007, 170:1077-1085
-
(2007)
Am J Pathol
, vol.170
, pp. 1077-1085
-
-
Céspedes, M.V.1
Espina, C.2
Garcia-Cabezas, M.A.3
Trias, M.4
Boluda, A.5
del Pulgar, M.T.6
Sancho, F.J.7
Nistal, M.8
Lacal, J.C.9
Mangues, R.10
-
24
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R: A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296:550-553
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
25
-
-
0035168740
-
Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation
-
Aznar S, Valeron PF, del Rincon SV, Perez LF, Perona R, Lacal JC: Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation. Mol Biol Cell 2001, 12:3282-3294
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3282-3294
-
-
Aznar, S.1
Valeron, P.F.2
del Rincon, S.V.3
Perez, L.F.4
Perona, R.5
Lacal, J.C.6
-
26
-
-
0033664012
-
Validation of a model of colon cancer progression
-
Hewitt RE, McMarlin A, Kleiner D, Wersto R, Martin P, Tsokos M, Stamp GW, Stetler-Stevenson WG: Validation of a model of colon cancer progression. J Pathol 2000, 192:446-454
-
(2000)
J Pathol
, vol.192
, pp. 446-454
-
-
Hewitt, R.E.1
McMarlin, A.2
Kleiner, D.3
Wersto, R.4
Martin, P.5
Tsokos, M.6
Stamp, G.W.7
Stetler-Stevenson, W.G.8
-
28
-
-
0027191250
-
-
Perona R, Esteve P, Jimenez B, Ballestero RP, Ramon y Cajal S, Lacal JC: Tumorigenic activity of rho genes from Aplysia californica. Oncogene 1993, 8:1285-1292
-
Perona R, Esteve P, Jimenez B, Ballestero RP, Ramon y Cajal S, Lacal JC: Tumorigenic activity of rho genes from Aplysia californica. Oncogene 1993, 8:1285-1292
-
-
-
-
29
-
-
0031577698
-
Rho proteins induce metastatic properties in vivo
-
del Peso L, Hernandez-Alcoceba R, Embade N, Carnero A, Esteve P, Paje C, Lacal JC: Rho proteins induce metastatic properties in vivo. Oncogene 1997, 15:3047-3057
-
(1997)
Oncogene
, vol.15
, pp. 3047-3057
-
-
del Peso, L.1
Hernandez-Alcoceba, R.2
Embade, N.3
Carnero, A.4
Esteve, P.5
Paje, C.6
Lacal, J.C.7
-
30
-
-
0029101360
-
An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
-
Olson MF, Ashworth A, Hall A: An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 1995, 269:1270-1272
-
(1995)
Science
, vol.269
, pp. 1270-1272
-
-
Olson, M.F.1
Ashworth, A.2
Hall, A.3
-
31
-
-
0036098594
-
Rho GTPase signalling pathways in the morphological changes associated with apoptosis
-
Coleman ML, Olson MF: Rho GTPase signalling pathways in the morphological changes associated with apoptosis. Cell Death Differ 2002, 9:493-504
-
(2002)
Cell Death Differ
, vol.9
, pp. 493-504
-
-
Coleman, M.L.1
Olson, M.F.2
-
32
-
-
85177018857
-
-
Jiménez B, Arends M, Esteve P, Perona R, Sanchez R, Ramon y Cajal S, Wyllie A, Lacal JC: Induction of apoptosis in NIH3T3 cells after serum deprivation by overexpression of rho-p21, a GTPase protein of the ras superfamily. Oncogene 1995, 10:811-816
-
Jiménez B, Arends M, Esteve P, Perona R, Sanchez R, Ramon y Cajal S, Wyllie A, Lacal JC: Induction of apoptosis in NIH3T3 cells after serum deprivation by overexpression of rho-p21, a GTPase protein of the ras superfamily. Oncogene 1995, 10:811-816
-
-
-
-
33
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst L, D'Souza-Schorey C: Rho GTPases and signaling networks. Genes Dev 1997, 11:2295-2322
-
(1997)
Genes Dev
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
34
-
-
0035964458
-
Ras and Rho regulation of the cell cycle and oncogenesis
-
Pruitt K, Der CJ: Ras and Rho regulation of the cell cycle and oncogenesis. Cancer Lett 2001, 171:1-10
-
(2001)
Cancer Lett
, vol.171
, pp. 1-10
-
-
Pruitt, K.1
Der, C.J.2
-
35
-
-
9944251987
-
Rho GTPases in human cancer: An unresolved link to upstream and downstream transcriptional regulation
-
Benitah SA, Valeron PF, van Aelst L, Marshall CJ, Lacal JC: Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochim Biophys Acta 2004, 1705:121-132
-
(2004)
Biochim Biophys Acta
, vol.1705
, pp. 121-132
-
-
Benitah, S.A.1
Valeron, P.F.2
van Aelst, L.3
Marshall, C.J.4
Lacal, J.C.5
-
36
-
-
0029079431
-
A role for Rac in Tiam1-induced membrane ruffling and invasion
-
Michiels F, Habets GG, Stam JC, van der Kammen RA, Collard JG: A role for Rac in Tiam1-induced membrane ruffling and invasion. Nature 1995, 375:338-340
-
(1995)
Nature
, vol.375
, pp. 338-340
-
-
Michiels, F.1
Habets, G.G.2
Stam, J.C.3
van der Kammen, R.A.4
Collard, J.G.5
-
38
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P: Wnt signaling and cancer. Genes Dev 2000, 14:1837-1851
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
39
-
-
0038637402
-
Gene expression pattern of laser microdissected colonic crypts of adenomas with low grade dysplasia
-
Lechner S, Muller-Ladner U, Renke B, Scholmerich J, Ruschoff J, Kullmann F: Gene expression pattern of laser microdissected colonic crypts of adenomas with low grade dysplasia. Gut 2003, 52:1148-1153
-
(2003)
Gut
, vol.52
, pp. 1148-1153
-
-
Lechner, S.1
Muller-Ladner, U.2
Renke, B.3
Scholmerich, J.4
Ruschoff, J.5
Kullmann, F.6
-
40
-
-
0031456065
-
Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion
-
Shaw LM, Rabinovitz I, Wang HH, Toker A, Mercurio AM: Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion. Cell 1997, 91:949-960
-
(1997)
Cell
, vol.91
, pp. 949-960
-
-
Shaw, L.M.1
Rabinovitz, I.2
Wang, H.H.3
Toker, A.4
Mercurio, A.M.5
-
42
-
-
26444582256
-
A novel mouse model for segmental orthotopic colon cancer
-
Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U: A novel mouse model for segmental orthotopic colon cancer. Int J Cancer 2005, 117:335-339
-
(2005)
Int J Cancer
, vol.117
, pp. 335-339
-
-
Alencar, H.1
King, R.2
Funovics, M.3
Stout, C.4
Weissleder, R.5
Mahmood, U.6
-
43
-
-
2942574538
-
Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
-
Flatmark K, Maelandsmo GM, Martinsen M, Rasmussen H, Fodstad O: Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. Eur J Cancer 2004, 40:1593-1598
-
(2004)
Eur J Cancer
, vol.40
, pp. 1593-1598
-
-
Flatmark, K.1
Maelandsmo, G.M.2
Martinsen, M.3
Rasmussen, H.4
Fodstad, O.5
-
44
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
Qiu RG, Chen J, Kirn D, McCormick F, Symons M: An essential role for Rac in Ras transformation. Nature 1995, 374:457-459
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.G.1
Chen, J.2
Kirn, D.3
McCormick, F.4
Symons, M.5
-
45
-
-
0029032053
-
Rho as a regulator of the cytoskeleton
-
Takai Y, Sasaki T, Tanaka K, Nakanishi H: Rho as a regulator of the cytoskeleton. Trends Biochem Sci 1995, 20:227-231
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 227-231
-
-
Takai, Y.1
Sasaki, T.2
Tanaka, K.3
Nakanishi, H.4
-
46
-
-
0031459917
-
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
-
Keely PJ, Westwick JK, Whitehead IP, Der CJ, Parise LV: Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 1997, 390:632-636
-
(1997)
Nature
, vol.390
, pp. 632-636
-
-
Keely, P.J.1
Westwick, J.K.2
Whitehead, I.P.3
CJ, D.4
Parise, L.V.5
-
47
-
-
0033615966
-
Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
-
Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG: Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 1999, 147:1009-1022
-
(1999)
J Cell Biol
, vol.147
, pp. 1009-1022
-
-
Sander, E.E.1
ten Klooster, J.P.2
van Delft, S.3
van der Kammen, R.A.4
Collard, J.G.5
-
48
-
-
0025222403
-
Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines
-
Murphy LD, Valverius EM, Tsokos M, Mickley LA, Rosen N, Bates SE: Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines. Cancer Commun 1990, 2:345-355
-
(1990)
Cancer Commun
, vol.2
, pp. 345-355
-
-
Murphy, L.D.1
Valverius, E.M.2
Tsokos, M.3
Mickley, L.A.4
Rosen, N.5
Bates, S.E.6
-
49
-
-
0028960781
-
Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells
-
Radinsky R, Risin S, Fan D, Dong Z, Bielenberg D, Bucana CD, Fidler IJ: Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res 1995, 1:19-31
-
(1995)
Clin Cancer Res
, vol.1
, pp. 19-31
-
-
Radinsky, R.1
Risin, S.2
Fan, D.3
Dong, Z.4
Bielenberg, D.5
Bucana, C.D.6
Fidler, I.J.7
-
50
-
-
2542452838
-
Pak-1 expression increases with progression of colorectal carcinomas to metastasis
-
Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, Pemberton JO, Konicek S, Hom J, Marshall M, Graff JR: Pak-1 expression increases with progression of colorectal carcinomas to metastasis. Clin Cancer Res 2004, 10:3448-3456
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3448-3456
-
-
Carter, J.H.1
Douglass, L.E.2
Deddens, J.A.3
Colligan, B.M.4
Bhatt, T.R.5
Pemberton, J.O.6
Konicek, S.7
Hom, J.8
Marshall, M.9
Graff, J.R.10
-
51
-
-
0033572701
-
Activated Rac1 selectively up-regulates the expression of integrin alpha6beta4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells
-
Mohri T, Adachi Y, Ikehara S, Hioki K, Tokunaga R, Taketani S: Activated Rac1 selectively up-regulates the expression of integrin alpha6beta4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells. Exp Cell Res 1999, 253:533-540
-
(1999)
Exp Cell Res
, vol.253
, pp. 533-540
-
-
Mohri, T.1
Adachi, Y.2
Ikehara, S.3
Hioki, K.4
Tokunaga, R.5
Taketani, S.6
-
52
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus MT, Sharp PA: Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002, 3:737-747
-
(2002)
Nat Rev Genet
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
53
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411:494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
54
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA: RNA interference in adult mice. Nature 2002, 418:38-39
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
Meuse, L.2
Pham, T.T.3
Conklin, D.S.4
Hannon, G.J.5
Kay, M.A.6
-
55
-
-
0037388638
-
Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells
-
Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB: Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res 2003, 9:1291-1300
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1291-1300
-
-
Verma, U.N.1
Surabhi, R.M.2
Schmaltieg, A.3
Becerra, C.4
Gaynor, R.B.5
-
56
-
-
0041335551
-
Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumor growth in a model of human ovarian cancer
-
Yang G, Thompson JA, Fang B, Liu J: Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumor growth in a model of human ovarian cancer. Oncogene 2003, 22:5694-5701
-
(2003)
Oncogene
, vol.22
, pp. 5694-5701
-
-
Yang, G.1
Thompson, J.A.2
Fang, B.3
Liu, J.4
-
57
-
-
3142743139
-
Inhibition of endothelial cell proliferation by targeting Rac1 GTPase with small interference RNA in tumor cells
-
Xue Y, Bi F, Zhang X, Pan Y, Liu N, Zheng Y, Fan D: Inhibition of endothelial cell proliferation by targeting Rac1 GTPase with small interference RNA in tumor cells. Biochem Biophys Res Commun 2004, 320:1309-1315
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 1309-1315
-
-
Xue, Y.1
Bi, F.2
Zhang, X.3
Pan, Y.4
Liu, N.5
Zheng, Y.6
Fan, D.7
-
58
-
-
28344456263
-
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
-
Chan AY, Coniglio SJ, Chuang YY, Michaelson D, Knaus UG, Philips MR, Symons M: Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion. Oncogene 2005, 24:7821-7829
-
(2005)
Oncogene
, vol.24
, pp. 7821-7829
-
-
Chan, A.Y.1
Coniglio, S.J.2
Chuang, Y.Y.3
Michaelson, D.4
Knaus, U.G.5
Philips, M.R.6
Symons, M.7
-
59
-
-
0037142034
-
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours
-
Malliri A, van der Kammen RA, Clark K, van der Valk M, Michiels F, Collard JG: Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours. Nature 2002, 417:867-871
-
(2002)
Nature
, vol.417
, pp. 867-871
-
-
Malliri, A.1
van der Kammen, R.A.2
Clark, K.3
van der Valk, M.4
Michiels, F.5
Collard, J.G.6
-
60
-
-
0344412931
-
Rac1 and Rac3 are targets for geranylgeranyltransferase I inhibitor-mediated inhibition of signaling, transformation, and membrane ruffling
-
Joyce PL, Cox AD: Rac1 and Rac3 are targets for geranylgeranyltransferase I inhibitor-mediated inhibition of signaling, transformation, and membrane ruffling. Cancer Res 2003, 63:7959-7967
-
(2003)
Cancer Res
, vol.63
, pp. 7959-7967
-
-
Joyce, P.L.1
Cox, A.D.2
-
61
-
-
0038375063
-
Inhibition of aggressiveness of metastatic mouse mammary carcinoma cells by the beta2-chimaerin GAP domain
-
Menna PL, Skilton G, Leskow FC, Alonso DF, Gomez DE, Kazanietz MG: Inhibition of aggressiveness of metastatic mouse mammary carcinoma cells by the beta2-chimaerin GAP domain. Cancer Res 2003, 63:2284-2291
-
(2003)
Cancer Res
, vol.63
, pp. 2284-2291
-
-
Menna, P.L.1
Skilton, G.2
Leskow, F.C.3
Alonso, D.F.4
Gomez, D.E.5
Kazanietz, M.G.6
-
62
-
-
2442664118
-
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
-
Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y: Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci USA 2004, 101:7618-7623
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 7618-7623
-
-
Gao, Y.1
Dickerson, J.B.2
Guo, F.3
Zheng, J.4
Zheng, Y.5
-
63
-
-
28544451354
-
FTY720: A promising agent for treatment of metastatic hepatocellular carcinoma
-
Lee TK, Man K, Ho JW, Wang XH, Poon RT, Xu Y, Ng KT, Chu AC, Sun CK, Ng IO, Sun HC, Tang ZY, Xu R, Fan ST: FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma. Clin Cancer Res 2005, 11:8458-8466
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8458-8466
-
-
Lee, T.K.1
Man, K.2
Ho, J.W.3
Wang, X.H.4
Poon, R.T.5
Xu, Y.6
Ng, K.T.7
Chu, A.C.8
Sun, C.K.9
Ng, I.O.10
Sun, H.C.11
Tang, Z.Y.12
Xu, R.13
Fan, S.T.14
-
64
-
-
14844343474
-
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice
-
Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang XY: Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice. Proc Natl Acad Sci USA 2005, 102:3772-3776
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3772-3776
-
-
Shan, D.1
Chen, L.2
Njardarson, J.T.3
Gaul, C.4
Ma, X.5
Danishefsky, S.J.6
Huang, X.Y.7
|