Pharmacokinetics and pharmacodynamics of phenethyl isothiocyanate: Implications in breast cancer prevention

AAPS Journal

Volumn 16, Issue 4, 2014, Pages 705-713

  Morris, Marilyn E ^a   Dave, Rutwij A ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

breast cancer resistance protein (BCRP); glutathione S transferase; multidrug resistance associated protein (MRP); PEITC; Phenethyl isothiocyanate

Indexed keywords

ABC TRANSPORTER; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; PHENETHYL ISOTHIOCYANATE; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; BINDING AFFINITY; BINDING SITE; BREAST CANCER; CANCER PREVENTION; CLINICAL EFFECTIVENESS; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; HUMAN; IC 50; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BREAST NEOPLASMS; FEMALE; RAT;

ANIMALS; ANTICARCINOGENIC AGENTS; BREAST NEOPLASMS; FEMALE; HUMANS; ISOTHIOCYANATES; RATS;

EID: 84903588171     PISSN: None     EISSN: 15507416     Source Type: Journal    
DOI: 10.1208/s12248-014-9610-y     Document Type: Review

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