Differential induction of apoptosis in human breast cancercell lines by phenethyl isothiocyanate, a glutathione depleting agent

Cell Stress and Chaperones

Volumn 17, Issue 5, 2012, Pages 529-538

  Syed Alwi, Sharifah S ^a   Cavell, Breeze E ^a   Donlevy, Alison ^a   Packham, Graham ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Breast cancer; Glutathione; NRF2; Phenethyl isothiocyante; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CASPASE 3; CASPASE 9; GLUTATHIONE; GLUTATHIONE DISULFIDE; PHENETHYL ISOTHIOCYANATE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRAIN BT549; CELL STRAIN MCF 7; CELL STRAIN MDA MB 231; CELL STRAIN SKBR3; CELL STRAIN T47D; CELL STRAIN ZR 75 1; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CASPASES; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; FEMALE; GLUTATHIONE; HUMANS; ISOTHIOCYANATES; MCF-7 CELLS; NF-E2-RELATED FACTOR 2; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84865148762     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-012-0329-3     Document Type: Article

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