Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats

Molecular Nutrition and Food Research

Volumn 54, Issue 3, 2010, Pages 426-432

  Konsue, Nattaya ^a   Kirkpatrick, Jo ^a   Kuhnert, Nikolai ^a   King, Laurie J ^a   Ioannides, Costas ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Chemoprevention; Isothiocyanates; Pharmacokinetics; Phenethyl isothiocyanate

Indexed keywords

ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE; PHENETHYL ISOTHIOCYANATE;

ANALYSIS; ANIMAL; ARTICLE; BIOAVAILABILITY; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; MALE; METABOLIC CLEARANCE RATE; ORAL DRUG ADMINISTRATION; RAT; STATISTICAL PARAMETERS; TIME; VEGETABLE; WISTAR RAT;

ADMINISTRATION, ORAL; ANALYTIC SAMPLE PREPARATION METHODS; ANIMALS; ANTICARCINOGENIC AGENTS; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAVENOUS; ISOTHIOCYANATES; LIMIT OF DETECTION; MALE; METABOLIC CLEARANCE RATE; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS; VEGETABLES;

ANIMALIA; RATTUS;

EID: 77649281731     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900090     Document Type: Article

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