Chemoprevention of lung cancer by isothiocyanates

Advances in Experimental Medicine and Biology

Volumn 401, Issue , 1996, Pages 1-11

  Hecht, Stephen S ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CARCINOGEN; ISOTHIOCYANIC ACID;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; CANCER PREVENTION; CARCINOGENESIS; CONFERENCE PAPER; LUNG CANCER; METABOLIC ACTIVATION; PRIORITY JOURNAL;

NASTURTIUM OFFICINALE; NICOTIANA TABACUM; RODENTIA;

EID: 0029837050     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4613-0399-2_1     Document Type: Conference Paper

References (34)

1. Sones, K., R.K. Heaney, and G.R. Fenwick, An estimate of the mean daily intake of glucosinolates from cruciferous vegetables in the U.K, J. Sci. Food Agric. 35:712 (1984).
2. Chung, F.-L., M.A. Morse, K.I. Eklind, and J. Lewis, Quantitation of human uptake of the anticarcinogen phenethyl isothiocyanate after a watercress meal, Cancer Epidemiol., Biomarkers Prev. 1:383 (1992).
3. Sasaki, S., Inhibitory effects by a-naphthylisothiocyanate on liver tumorigenesis in rats treated with 3′-methyl-4-dimethyl-aminoazobenzene, J. Nara Med. Assoc. 14:101 (1963).
4. Sidransky, H., N. Ito, and E. Verney, Influence of a-naphthyl-isothiocyanate on liver tumorigenesis in rats ingesting ethionine and N-2-fluorenylacetamide, J. Natl. Cancer Inst. 37:677 (1966).
5. Lacassagne, A., L. Hurst, and M.D. Xuong, Inhibition, par deux naphthylisothiocyanates, de l'hepatocancérogenèse produit, chez le rat, par le p-diméthylaminoazobenzène (DAB), C.R. Séances Soc. Biol. Fil. 164:230 (1970).
6. Ito, N., Y. Hiasa, Y. Konishi, and M. Marugami, The development of carcinoma in liver of rats treated with m-toluylenediamine and the synergistic and antagonistic effects with other chemicals, Cancer Res. 29:1137 (1969).
7. Makiura, S., Y. Kamamoto, S. Sugihara, K. Hirao, Y. Hiasa, M. Arai, and N. Ito, Effect of 1-naphthyl isothiocyanate and 3-methylcholanthrene on hepatocarcinogenesis in rats treated with diethylnitrosoamine, Jpn. J. Cancer Res. 64:101 (1973).
8. Ito, N., K. Matayoshi, K. Matsumura, A. Denda, T. Kani, M. Arai, and S. Makiura, Effect of various carcinogenic and non-carcinogenic substances on development of bladder tumors in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosoamine, Jpn. J. Cancer Res. 65:123 (1974).
9. Wattenberg, L.W., Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds, J. Natl. Cancer Inst. 58:395 (1977).
10. 6methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung, Cancer Res. 49:2894 (1989).
11. Wattenberg, L.W., Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure, Cancer Res. 41:2991 (1981).
12. Wattenberg, L.W., Inhibitory effects of benzyl isothiocyanate administered shortly before diethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice, Carcinogenesis 8:1971 (1987).
13. Lin, J.-M., S. Amin, N. Trushin, and S.S. Hecht, Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models, Cancer Lett. 74:151 (1993).
14. Morse, M.A., J.C. Reinhardt, S.G. Amin, S.S. Hecht, G.D. Stoner, and F.-L. Chung, Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice, Cancer Lett. 49:225 (1990).
15. Sugie, S., A. Okumura, T. Tanaka, and H. Mori, Inhibitory effects of benzyl isothiocyanate and benzyl thiocyanate on diethylnitrosamine-induced hepatocarcinogenesis in rats, Jpn. J. Cancer Res. 84:865 (1993).
16. Sugie, S., K. Okamoto, A. Okumura, T. Tanaka, and H. Mori, Inhibitory effects of benzyl thiocyanate and benzyl isothiocyanate on methylazoxymethanol acetate-induced intestinal carcinogcnesis in rats, Carcinogenesis 15:1555 (1994).
17. Morse, M.A., C.-X. Wang, G.D. Stoner, S. Mandal, P.B. Conran, S.G. Amin, S.S. Hecht, and F.-L. Chung, Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in lung of F344 rats by dietary phenethyl isothiocyanate, Cancer Res. 49:549 (1989).
18. Morse, M.A., K.I. Eklind, S.G. Amin, S.S. Hecht, and F.-L. Chung, Effects of alkyl chain length on the inhibition of NNKinduced lung neoplasia in A/J mice by arylalkyl isothiocyanates, Carcinogenesis 10:1757 (1989).
19. Morse, M.A., K.I. Eklind, S.S. Hecht, K.G. Jordan, C.-I. Choi, D.H. Desai, S.G. Amin, and F.-L. Chung, Structure-activity relationships for inhibition of 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice, Cancer Res. 51:1846 (1991).
20. Morse, M.A., K.E. Eklind, S.G. Amin, and F.L. Chung, Effect of frequency of isothiocyanate administration on inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary ademona formation in A/J mice, Cancer Lett. 62:77 (1992).
21. Stoner, G.D., D. Morrissey, Y.-H. Heur, E. Daniel, A. Galati, and S.A. Wagner, Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethytamine carcinogenesis in the rat esophagus, Cancer Res. 51:2063 (1991).
22. Adam-Rodwell, G., M.A. Morse, and G.D. Stoner, The effects of phenethyl isothiocyanate on benzo[a]pyrene-induced tumors and DNA adducts in A/J mouse lung, Cancer Lett. 71:35 (1993).
23. Jiao, D., K.I. Eklind, C.I. Choi, D.H. Desai, S.G. Amin, and F.L. Chung, Structure-activity relationships of isothiocyanates as mechanism-based inhibitors of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice, Cancer Res. 54:4327 (1994).
24. Zhang, Y., T.W. Kensler, C.-G. Cho, G.H. Posner, and P. Talalay, Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates, Proc. Natl. Acad. Sci. USA 91:3147 (1994).
25. Hecht, S.S., Chemoprevention by isothiocyanates, J. Cell. Biochem. [Suppl.] 22:195 (1995).
26. Yang, C.S., T.J. Smith, and J.-Y. Hong, Cytochrome P-450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations, Cancer Res. 54:1982s (1994).
27. Zhang, Y. and P. Talalay, Amicarcinogenic activities of organic isothiocyanates: chemistry and mechanisms, Cancer Res. 54:1976s (1994).
28. Guo, Z., T.J. Smith, E. Wang, K.I. Eklind, F.-L. Chung, and C.S. Yang, Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice, Carcinogenesis 14:1167 (1993).
29. Wingo, P.A., T. Tong, and S. Bolden, Cancer statistics, 1995, CA 45:8 (1995).
30. Shopland, D.R., H.J. Eyre, and T.F. Pechachek, Smoking-attributable cancer mortality in 1991: Is lung cancer now the leading cause of death among smokers in the United States?, J. Natl. Cancer Inst. 83:1142 (1991).
31. Hecht, S.S., Metabolic activation and detoxification of tobacco-specific nitrosamines-a model for cancer prevention strategies, Drug Metab. Rev. 26:373 (1994).
32. Hecht, S.S., S.G. Carmella, P.G. Foiles, and S.E. Murphy, Biomarkers for human uptake and metabolic activation of tobacco-specific nitrosamines, Cancer Res. 54:1912s (1994).
33. Doerr-O'Rourke, K., N. Trushin, S.S. Hecht, and G.D. Stoner, Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue, Carcinogenesis 12:1029 (1991).
34. Staretz, M.E. and S.S. Hecht, Effects of phenethyl isothiocyanate on the tissue distribution of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites in F344 rats, submitted (1995).