Modulation of carcinogen-metabolising cytochromes P450 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables

Toxicology

Volumn 268, Issue 3, 2010, Pages 184-190

  Konsue, Nattaya ^a   Ioannides, Costas ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Chemoprevention; Cytochrome P450; Glucosinolates; Isothiocyanates; Phenethyl isothiocyanate

Indexed keywords

AMINE; CARCINOGEN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 3A; CYTOCHROME P450 3A4; ETHOXYRESORUFIN; PHENETHYL ISOTHIOCYANATE; POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; AGED; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DEALKYLATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; HUMAN; HUMAN TISSUE; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TOXICOKINETICS;

ADULT; AGED; ANIMALS; ANTICARCINOGENIC AGENTS; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; ISOENZYMES; ISOTHIOCYANATES; L-LACTATE DEHYDROGENASE; LIVER; MALE; MIDDLE AGED; MIXED FUNCTION OXYGENASES; RATS; RATS, WISTAR; VEGETABLES;

ANIMALIA; RATTUS;

EID: 76749135648     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.12.011     Document Type: Article

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