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Volumn 8, Issue 6, 2013, Pages

Metastasis of Breast Tumor Cells to Brain Is Suppressed by Phenethyl Isothiocyanate in a Novel In Vivo Metastasis Model

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; PHENETHYL ISOTHIOCYANATE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE; LUCIFERASE; QUANTUM DOT;

EID: 84879533925     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067278     Document Type: Article
Times cited : (59)

References (59)
  • 1
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: a question of life or death
    • Mehlen P, Puisieux A, (2006) Metastasis: a question of life or death. Nat Rev Cancer 6: 449-458.
    • (2006) Nat Rev Cancer , vol.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 2
    • 31444447160 scopus 로고    scopus 로고
    • Extending survival with chemotherapy in metastatic breast cancer
    • O'Shaughnessy J, (2005) Extending survival with chemotherapy in metastatic breast cancer. Oncologist 10Suppl 3: 20-29.
    • (2005) Oncologist , vol.10 , pp. 20-29
    • O'Shaughnessy, J.1
  • 4
    • 0141888540 scopus 로고    scopus 로고
    • Diagnosis and management of central nervous system metastases from breast cancer
    • Chang EL, Lo S, (2003) Diagnosis and management of central nervous system metastases from breast cancer. Oncologist 8: 398-410.
    • (2003) Oncologist , vol.8 , pp. 398-410
    • Chang, E.L.1    Lo, S.2
  • 6
    • 84861459371 scopus 로고    scopus 로고
    • Incidence and time trends of brain metastases admissions among breast cancer patients in Sweden
    • Frisk G, Svensson T, Backlund LM, Lidbrink E, Blomqvist P, et al. (2012) Incidence and time trends of brain metastases admissions among breast cancer patients in Sweden. Br J Cancer 106: 1850-1853.
    • (2012) Br J Cancer , vol.106 , pp. 1850-1853
    • Frisk, G.1    Svensson, T.2    Backlund, L.M.3    Lidbrink, E.4    Blomqvist, P.5
  • 10
    • 34249317254 scopus 로고    scopus 로고
    • Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain
    • Palmieri D, Bronder JL, Herring JM, Yoneda T, Weil RJ, et al. (2007) Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res 67: 4190-4198.
    • (2007) Cancer Res , vol.67 , pp. 4190-4198
    • Palmieri, D.1    Bronder, J.L.2    Herring, J.M.3    Yoneda, T.4    Weil, R.J.5
  • 11
    • 79957547465 scopus 로고    scopus 로고
    • Brain metastasis of breast tumors and blood brain barrier
    • Dieras V, Pierga JY, (2011) Brain metastasis of breast tumors and blood brain barrier. Bull Cancer 98: 385-389.
    • (2011) Bull Cancer , vol.98 , pp. 385-389
    • Dieras, V.1    Pierga, J.Y.2
  • 12
    • 79952809869 scopus 로고    scopus 로고
    • Basal phenotype breast cancer: implications for treatment and prognosis
    • Pazaiti A, Fentiman IS, (2011) Basal phenotype breast cancer: implications for treatment and prognosis. Womens Health (Lond Engl) 7: 181-202.
    • (2011) Womens Health (Lond Engl) , vol.7 , pp. 181-202
    • Pazaiti, A.1    Fentiman, I.S.2
  • 13
    • 79952073192 scopus 로고    scopus 로고
    • The role of the organ microenvironment in brain metastasis
    • Fidler IJ, (2011) The role of the organ microenvironment in brain metastasis. Semin Cancer Biol 21: 107-112.
    • (2011) Semin Cancer Biol , vol.21 , pp. 107-112
    • Fidler, I.J.1
  • 14
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: opportunities (and problems) for cancer therapy
    • Brown JM, Giaccia AJ, (1998) The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 58: 1408-1416.
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 15
    • 0023616760 scopus 로고
    • Quantitative study of microvessel ultrastructure in human peritumoral brain tissue. Evidence for a blood-brain barrier defect
    • Stewart PA, Hayakawa K, Farrell CL, Del Maestro RF, (1987) Quantitative study of microvessel ultrastructure in human peritumoral brain tissue. Evidence for a blood-brain barrier defect. J Neurosurg 67: 697-705.
    • (1987) J Neurosurg , vol.67 , pp. 697-705
    • Stewart, P.A.1    Hayakawa, K.2    Farrell, C.L.3    Del Maestro, R.F.4
  • 16
    • 0034282780 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis
    • Yano S, Shinohara H, Herbst RS, Kuniyasu H, Bucana CD, et al. (2000) Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis. Cancer Res 60: 4959-4967.
    • (2000) Cancer Res , vol.60 , pp. 4959-4967
    • Yano, S.1    Shinohara, H.2    Herbst, R.S.3    Kuniyasu, H.4    Bucana, C.D.5
  • 17
    • 0022296370 scopus 로고
    • Diet, nutrition, and cancer
    • Palmer S, (1985) Diet, nutrition, and cancer. Prog Food Nutr Sci 9: 283-341.
    • (1985) Prog Food Nutr Sci , vol.9 , pp. 283-341
    • Palmer, S.1
  • 18
    • 78649674127 scopus 로고    scopus 로고
    • Fruit and vegetable intake in relation to risk of breast cancer in the Black Women's Health Study
    • Boggs DA, Palmer JR, Wise LA, Spiegelman D, Stampfer MJ, et al. (2010) Fruit and vegetable intake in relation to risk of breast cancer in the Black Women's Health Study. Am J Epidemiol 172: 1268-1279.
    • (2010) Am J Epidemiol , vol.172 , pp. 1268-1279
    • Boggs, D.A.1    Palmer, J.R.2    Wise, L.A.3    Spiegelman, D.4    Stampfer, M.J.5
  • 19
    • 40549137444 scopus 로고    scopus 로고
    • Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk
    • Lee SA, Fowke JH, Lu W, Ye C, Zheng Y, et al. (2008) Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk. Am J Clin Nutr 87: 753-760.
    • (2008) Am J Clin Nutr , vol.87 , pp. 753-760
    • Lee, S.A.1    Fowke, J.H.2    Lu, W.3    Ye, C.4    Zheng, Y.5
  • 20
    • 77950464161 scopus 로고    scopus 로고
    • A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women
    • Butler LM, Wu AH, Wang R, Koh WP, Yuan JM, et al. (2010) A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women. Am J Clin Nutr 91: 1013-1019.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1013-1019
    • Butler, L.M.1    Wu, A.H.2    Wang, R.3    Koh, W.P.4    Yuan, J.M.5
  • 21
    • 0017508066 scopus 로고
    • Glucosinolates and derived products in cruciferous vegetables: gas-liquid chromatographic determination of the aglucon derivatives from cabbage
    • Daxenbichler ME, VanEtten CH, (1977) Glucosinolates and derived products in cruciferous vegetables: gas-liquid chromatographic determination of the aglucon derivatives from cabbage. J Assoc Off Anal Chem 60: 950-953.
    • (1977) J Assoc Off Anal Chem , vol.60 , pp. 950-953
    • Daxenbichler, M.E.1    VanEtten, C.H.2
  • 22
    • 79960708197 scopus 로고    scopus 로고
    • Biological targets of isothiocyanates
    • Brown KK, Hampton MB, (2011) Biological targets of isothiocyanates. Biochim Biophys Acta 1810: 888-894.
    • (2011) Biochim Biophys Acta , vol.1810 , pp. 888-894
    • Brown, K.K.1    Hampton, M.B.2
  • 23
    • 0034538640 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by isothiocyanates
    • Hecht SS, (2000) Inhibition of carcinogenesis by isothiocyanates. Drug Metab Rev 32: 395-411.
    • (2000) Drug Metab Rev , vol.32 , pp. 395-411
    • Hecht, S.S.1
  • 24
    • 34548290810 scopus 로고    scopus 로고
    • Targeting ROS: selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound
    • Wu XJ, Hua X, (2007) Targeting ROS: selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound. Cancer Biol Ther 6: 646-647.
    • (2007) Cancer Biol Ther , vol.6 , pp. 646-647
    • Wu, X.J.1    Hua, X.2
  • 25
    • 77449106593 scopus 로고    scopus 로고
    • Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention
    • Cheung KL, Kong AN, (2010) Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention. AAPS J 12: 87-97.
    • (2010) AAPS J , vol.12 , pp. 87-97
    • Cheung, K.L.1    Kong, A.N.2
  • 26
    • 79961075772 scopus 로고    scopus 로고
    • Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma
    • Jakubikova J, Cervi D, Ooi M, Kim K, Nahar S, et al. (2011) Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma. Haematologica 96: 1170-1179.
    • (2011) Haematologica , vol.96 , pp. 1170-1179
    • Jakubikova, J.1    Cervi, D.2    Ooi, M.3    Kim, K.4    Nahar, S.5
  • 27
    • 79959982112 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways
    • Gao N, Budhraja A, Cheng S, Liu EH, Chen J, et al. (2011) Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways. Cell Death Dis 2: e140.
    • (2011) Cell Death Dis , vol.2
    • Gao, N.1    Budhraja, A.2    Cheng, S.3    Liu, E.H.4    Chen, J.5
  • 28
    • 79958859670 scopus 로고    scopus 로고
    • Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells
    • Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, et al. (2011) Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells. J Orthop Res 29: 1199-1209.
    • (2011) J Orthop Res , vol.29 , pp. 1199-1209
    • Wu, C.L.1    Huang, A.C.2    Yang, J.S.3    Liao, C.L.4    Lu, H.F.5
  • 29
    • 77955072957 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways
    • Yang MD, Lai KC, Lai TY, Hsu SC, Kuo CL, et al. (2010) Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. Anticancer Res 30: 2135-2143.
    • (2010) Anticancer Res , vol.30 , pp. 2135-2143
    • Yang, M.D.1    Lai, K.C.2    Lai, T.Y.3    Hsu, S.C.4    Kuo, C.L.5
  • 30
    • 0032968691 scopus 로고    scopus 로고
    • Disposition and pharmacokinetics of phenethyl isothiocyanate and 6-phenylhexyl isothiocyanate in F344 rats
    • Conaway CC, Jiao D, Kohri T, Liebes L, Chung FL, (1999) Disposition and pharmacokinetics of phenethyl isothiocyanate and 6-phenylhexyl isothiocyanate in F344 rats. Drug Metab Dispos 27: 13-20.
    • (1999) Drug Metab Dispos , vol.27 , pp. 13-20
    • Conaway, C.C.1    Jiao, D.2    Kohri, T.3    Liebes, L.4    Chung, F.L.5
  • 31
    • 77953186750 scopus 로고    scopus 로고
    • Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells
    • Wu X, Zhu Y, Yan H, Liu B, Li Y, et al. (2010) Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells. BMC Cancer 10: 269.
    • (2010) BMC Cancer , vol.10 , pp. 269
    • Wu, X.1    Zhu, Y.2    Yan, H.3    Liu, B.4    Li, Y.5
  • 32
    • 84867888901 scopus 로고    scopus 로고
    • Anti-tumor activity of phenethyl isothiocyanate in HER2 positive breast cancer models
    • Gupta P, Srivastava SK, (2012) Anti-tumor activity of phenethyl isothiocyanate in HER2 positive breast cancer models. BMC Med 10: 80.
    • (2012) BMC Med , vol.10 , pp. 80
    • Gupta, P.1    Srivastava, S.K.2
  • 33
    • 84865217843 scopus 로고    scopus 로고
    • Diindolylmethane mediated Gli1 Suppression Induces Anoikis in Ovarian Cancer cells in vitro and blocks tumor formation ability in vivo
    • Kandala PK, Srivastava SK (2012) Diindolylmethane mediated Gli1 Suppression Induces Anoikis in Ovarian Cancer cells in vitro and blocks tumor formation ability in vivo. J Biol Chem.
    • (2012) J Biol Chem
    • Kandala, P.K.1    Srivastava, S.K.2
  • 34
    • 84865204083 scopus 로고    scopus 로고
    • Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK
    • Kandala PK, Srivastava SK, (2012) Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK. Oncotarget 3: 435-449.
    • (2012) Oncotarget , vol.3 , pp. 435-449
    • Kandala, P.K.1    Srivastava, S.K.2
  • 35
    • 0034912833 scopus 로고    scopus 로고
    • A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro
    • Yoneda T, Williams PJ, Hiraga T, Niewolna M, Nishimura R, (2001) A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro. J Bone Miner Res 16: 1486-1495.
    • (2001) J Bone Miner Res , vol.16 , pp. 1486-1495
    • Yoneda, T.1    Williams, P.J.2    Hiraga, T.3    Niewolna, M.4    Nishimura, R.5
  • 36
    • 70349671463 scopus 로고    scopus 로고
    • Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks
    • Palmieri D, Lockman PR, Thomas FC, Hua E, Herring J, et al. (2009) Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks. Clin Cancer Res 15: 6148-6157.
    • (2009) Clin Cancer Res , vol.15 , pp. 6148-6157
    • Palmieri, D.1    Lockman, P.R.2    Thomas, F.C.3    Hua, E.4    Herring, J.5
  • 37
    • 78650378532 scopus 로고    scopus 로고
    • Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer
    • Lockman PR, Mittapalli RK, Taskar KS, Rudraraju V, Gril B, et al. (2010) Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer. Clin Cancer Res 16: 5664-5678.
    • (2010) Clin Cancer Res , vol.16 , pp. 5664-5678
    • Lockman, P.R.1    Mittapalli, R.K.2    Taskar, K.S.3    Rudraraju, V.4    Gril, B.5
  • 38
    • 0018373097 scopus 로고
    • Development of a metastatic brain tumor model in mice
    • Conley FK, (1979) Development of a metastatic brain tumor model in mice. Cancer Res 39: 1001-1007.
    • (1979) Cancer Res , vol.39 , pp. 1001-1007
    • Conley, F.K.1
  • 39
    • 65549085146 scopus 로고    scopus 로고
    • Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
    • Sahu RP, Batra S, Srivastava SK, (2009) Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells. Br J Cancer 100: 1425-1433.
    • (2009) Br J Cancer , vol.100 , pp. 1425-1433
    • Sahu, R.P.1    Batra, S.2    Srivastava, S.K.3
  • 40
    • 80053925842 scopus 로고    scopus 로고
    • Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3
    • Boreddy SR, Sahu RP, Srivastava SK, (2011) Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3. PLoS One 6: e25799.
    • (2011) PLoS One , vol.6
    • Boreddy, S.R.1    Sahu, R.P.2    Srivastava, S.K.3
  • 41
    • 0021050124 scopus 로고
    • Central nervous system metastasis from breast carcinoma. Autopsy study
    • Tsukada Y, Fouad A, Pickren JW, Lane WW, (1983) Central nervous system metastasis from breast carcinoma. Autopsy study. Cancer 52: 2349-2354.
    • (1983) Cancer , vol.52 , pp. 2349-2354
    • Tsukada, Y.1    Fouad, A.2    Pickren, J.W.3    Lane, W.W.4
  • 42
    • 84856611805 scopus 로고    scopus 로고
    • Bone cancer in 2011: Prevention and treatment of bone metastases
    • Coleman RE, (2012) Bone cancer in 2011: Prevention and treatment of bone metastases. Nat Rev Clin Oncol 9: 76-78.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 76-78
    • Coleman, R.E.1
  • 43
    • 84863015686 scopus 로고    scopus 로고
    • Preventive effects of zoledronic acid on bone metastasis in mice injected with human breast cancer cells
    • Jeong J, Lee KS, Choi YK, Oh YJ, Lee HD, (2011) Preventive effects of zoledronic acid on bone metastasis in mice injected with human breast cancer cells. J Korean Med Sci 26: 1569-1575.
    • (2011) J Korean Med Sci , vol.26 , pp. 1569-1575
    • Jeong, J.1    Lee, K.S.2    Choi, Y.K.3    Oh, Y.J.4    Lee, H.D.5
  • 44
    • 84865179740 scopus 로고    scopus 로고
    • Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases
    • Tsao MN, Lloyd N, Wong RK, Chow E, Rakovitch E, et al. (2012) Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases. Cochrane Database Syst Rev 4: CD003869.
    • (2012) Cochrane Database Syst Rev , vol.4
    • Tsao, M.N.1    Lloyd, N.2    Wong, R.K.3    Chow, E.4    Rakovitch, E.5
  • 45
    • 84958665440 scopus 로고    scopus 로고
    • gamma knife radiosurgery of brain metastasis from breast cancer
    • Padovani L, Muracciole X, Regis J, (2012) gamma knife radiosurgery of brain metastasis from breast cancer. Prog Neurol Surg 25: 156-162.
    • (2012) Prog Neurol Surg , vol.25 , pp. 156-162
    • Padovani, L.1    Muracciole, X.2    Regis, J.3
  • 46
    • 79958209681 scopus 로고    scopus 로고
    • Quantum dots-based double-color imaging of HER2 positive breast cancer invasion
    • Liu XL, Peng CW, Chen C, Yang XQ, Hu MB, et al. (2011) Quantum dots-based double-color imaging of HER2 positive breast cancer invasion. Biochem Biophys Res Commun 409: 577-582.
    • (2011) Biochem Biophys Res Commun , vol.409 , pp. 577-582
    • Liu, X.L.1    Peng, C.W.2    Chen, C.3    Yang, X.Q.4    Hu, M.B.5
  • 47
    • 0030054914 scopus 로고    scopus 로고
    • Regulation of VEGF/VPF expression in tumor cells: consequences for tumor growth and metastasis
    • Claffey KP, Robinson GS, (1996) Regulation of VEGF/VPF expression in tumor cells: consequences for tumor growth and metastasis. Cancer Metastasis Rev 15: 165-176.
    • (1996) Cancer Metastasis Rev , vol.15 , pp. 165-176
    • Claffey, K.P.1    Robinson, G.S.2
  • 48
    • 84861151214 scopus 로고    scopus 로고
    • Expression of survivin and VEGF-C in breast cancer tissue and its relation to lymphatic metastasis
    • Li X, Dang X, Sun X, (2012) Expression of survivin and VEGF-C in breast cancer tissue and its relation to lymphatic metastasis. Eur J Gynaecol Oncol 33: 178-182.
    • (2012) Eur J Gynaecol Oncol , vol.33 , pp. 178-182
    • Li, X.1    Dang, X.2    Sun, X.3
  • 49
    • 84866481797 scopus 로고    scopus 로고
    • Mesenchymal stem cells-derived interleukin-6 and vascular endothelial growth factor promote breast cancer cell migration
    • De Luca A, Lamura L, Gallo M, Maffia V, Normanno N, (2012) Mesenchymal stem cells-derived interleukin-6 and vascular endothelial growth factor promote breast cancer cell migration. J Cell Biochem 113: 3363-3370.
    • (2012) J Cell Biochem , vol.113 , pp. 3363-3370
    • De Luca, A.1    Lamura, L.2    Gallo, M.3    Maffia, V.4    Normanno, N.5
  • 50
    • 22744440329 scopus 로고    scopus 로고
    • Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells
    • Xu C, Shen G, Chen C, Gelinas C, Kong AN, (2005) Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells. Oncogene 24: 4486-4495.
    • (2005) Oncogene , vol.24 , pp. 4486-4495
    • Xu, C.1    Shen, G.2    Chen, C.3    Gelinas, C.4    Kong, A.N.5
  • 51
    • 65749104457 scopus 로고    scopus 로고
    • Inhibition of hypoxia inducible factor by phenethyl isothiocyanate
    • Wang XH, Cavell BE, Syed Alwi SS, Packham G, (2009) Inhibition of hypoxia inducible factor by phenethyl isothiocyanate. Biochem Pharmacol 78: 261-272.
    • (2009) Biochem Pharmacol , vol.78 , pp. 261-272
    • Wang, X.H.1    Cavell, B.E.2    Syed Alwi, S.S.3    Packham, G.4
  • 52
    • 84860629063 scopus 로고    scopus 로고
    • EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin alphavbeta5 Depends on Activation of c-Src and Cleavage of MUC1
    • Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, et al. (2012) EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin alphavbeta5 Depends on Activation of c-Src and Cleavage of MUC1. PLoS One 7: e36753.
    • (2012) PLoS One , vol.7
    • Lau, S.K.1    Shields, D.J.2    Murphy, E.A.3    Desgrosellier, J.S.4    Anand, S.5
  • 53
    • 84866341984 scopus 로고    scopus 로고
    • Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis
    • Nie F, Yang J, Wen S, An YL, Ding J, et al. (2012) Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis. Cancer 118: 5198-5209.
    • (2012) Cancer , vol.118 , pp. 5198-5209
    • Nie, F.1    Yang, J.2    Wen, S.3    An, Y.L.4    Ding, J.5
  • 54
    • 84855992589 scopus 로고    scopus 로고
    • Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad
    • Nickerson NK, Mohammad KS, Gilmore JL, Crismore E, Bruzzaniti A, et al. (2012) Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad. PLoS One 7: e30255.
    • (2012) PLoS One , vol.7
    • Nickerson, N.K.1    Mohammad, K.S.2    Gilmore, J.L.3    Crismore, E.4    Bruzzaniti, A.5
  • 55
    • 33644869673 scopus 로고    scopus 로고
    • Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin
    • Kim JH, Xu C, Keum YS, Reddy B, Conney A, et al. (2006) Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin. Carcinogenesis 27: 475-482.
    • (2006) Carcinogenesis , vol.27 , pp. 475-482
    • Kim, J.H.1    Xu, C.2    Keum, Y.S.3    Reddy, B.4    Conney, A.5
  • 57
    • 0027193418 scopus 로고
    • Brain metastases in breast cancer; natural history, prognostic factors and outcome
    • Boogerd W, Vos VW, Hart AA, Baris G, (1993) Brain metastases in breast cancer; natural history, prognostic factors and outcome. J Neurooncol 15: 165-174.
    • (1993) J Neurooncol , vol.15 , pp. 165-174
    • Boogerd, W.1    Vos, V.W.2    Hart, A.A.3    Baris, G.4
  • 58
    • 0023777633 scopus 로고
    • Breast cancer: metastatic patterns and their prognosis
    • Patanaphan V, Salazar OM, Risco R, (1988) Breast cancer: metastatic patterns and their prognosis. South Med J 81: 1109-1112.
    • (1988) South Med J , vol.81 , pp. 1109-1112
    • Patanaphan, V.1    Salazar, O.M.2    Risco, R.3
  • 59
    • 25144443075 scopus 로고    scopus 로고
    • Pharmacokinetics of dietary phenethyl isothiocyanate in rats
    • Ji Y, Kuo Y, Morris ME, (2005) Pharmacokinetics of dietary phenethyl isothiocyanate in rats. Pharm Res 22: 1658-1666.
    • (2005) Pharm Res , vol.22 , pp. 1658-1666
    • Ji, Y.1    Kuo, Y.2    Morris, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.