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Volumn 102, Issue 3, 2013, Pages 787-793

Interindividual variability in the hepatic expression of the human breast cancer resistance protein (BCRP/ABCG2): Effect of age, sex, and genotype

Author keywords

ABC transporters; Breast cancer resistance protein; Drug transport; Genetic polymorphisms; Hepatic transport; Hepatobiliary disposition

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; STABLE ISOTOPE;

EID: 84878129920     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23436     Document Type: Article
Times cited : (100)

References (35)
  • 2
    • 71949102481 scopus 로고    scopus 로고
    • Interplay of drug metabolism and transport: A real phenomenon or an artifact of the site of measurement
    • Endres CJ, Endres MG, Unadkat JD. 2009. Interplay of drug metabolism and transport: A real phenomenon or an artifact of the site of measurement? Mol Pharm 6(6):1756-1765.
    • (2009) Mol Pharm , vol.6 , Issue.6 , pp. 1756-1765
    • Endres, C.J.1    Endres, M.G.2    Unadkat, J.D.3
  • 4
    • 66149097607 scopus 로고    scopus 로고
    • Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3
    • Govindarajan R, Leung GP, Zhou M, Tse CM, Wang J, Unadkat JD. 2009. Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3. Am J Physiol Gastrointest Liver Physiol 296(4):G910-G922.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , Issue.4
    • Govindarajan, R.1    Leung, G.P.2    Zhou, M.3    Tse, C.M.4    Wang, J.5    Unadkat, J.D.6
  • 5
    • 1042301403 scopus 로고    scopus 로고
    • Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs
    • Lai Y, Tse CM, Unadkat JD. 2004. Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs. J Biol Chem 279(6):4490-4497.
    • (2004) J Biol Chem , vol.279 , Issue.6 , pp. 4490-4497
    • Lai, Y.1    Tse, C.M.2    Unadkat, J.D.3
  • 6
    • 84859899906 scopus 로고    scopus 로고
    • Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): Quantification by liquid chromatography/tandem mass spectrometry
    • Deo AK, Prasad B, Balogh L, Lai Y, Unadkat JD. 2012. Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): Quantification by liquid chromatography/tandem mass spectrometry. Drug Metab Dispos 40(5):852-855.
    • (2012) Drug Metab Dispos , vol.40 , Issue.5 , pp. 852-855
    • Deo, A.K.1    Prasad, B.2    Balogh, L.3    Lai, Y.4    Unadkat, J.D.5
  • 7
    • 64649105304 scopus 로고    scopus 로고
    • LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species
    • Li N, Palandra J, Nemirovskiy OV, Lai Y. 2009. LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species. Anal Chem 81(6):2251-2259.
    • (2009) Anal Chem , vol.81 , Issue.6 , pp. 2251-2259
    • Li, N.1    Palandra, J.2    Nemirovskiy, O.V.3    Lai, Y.4
  • 8
    • 84455194082 scopus 로고    scopus 로고
    • Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: Comparison with mRNA levels and activities
    • Ohtsuki S, Schaefer O, Kawakami H, Inoue T, Liehner S, Saito A, Ishiguro N, Kishimoto W, Ludwig-Schwellinger E, Ebner T, Terasaki T. 2012. Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: Comparison with mRNA levels and activities. Drug Metab Dispos 40(1):83-92.
    • (2012) Drug Metab Dispos , vol.40 , Issue.1 , pp. 83-92
    • Ohtsuki, S.1    Schaefer, O.2    Kawakami, H.3    Inoue, T.4    Liehner, S.5    Saito, A.6    Ishiguro, N.7    Kishimoto, W.8    Ludwig-Schwellinger, E.9    Ebner, T.10    Terasaki, T.11
  • 9
    • 43049114146 scopus 로고    scopus 로고
    • Quantitative atlas of membrane transporter proteins: Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria
    • Kamiie J, Ohtsuki S, Iwase R, Ohmine K, Katsukura Y, Yanai K, Sekine Y, Uchida Y, Ito S, Terasaki T. 2008. Quantitative atlas of membrane transporter proteins: Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria. Pharm Res 25(6):1469-1483.
    • (2008) Pharm Res , vol.25 , Issue.6 , pp. 1469-1483
    • Kamiie, J.1    Ohtsuki, S.2    Iwase, R.3    Ohmine, K.4    Katsukura, Y.5    Yanai, K.6    Sekine, Y.7    Uchida, Y.8    Ito, S.9    Terasaki, T.10
  • 10
    • 84455163180 scopus 로고    scopus 로고
    • Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytes
    • Schaefer O, Ohtsuki S, Kawakami H, Inoue T, Liehner S, Saito A, Sakamoto A, Ishiguro N, Matsumaru T, Terasaki T, Ebner T. 2012. Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytes. Drug Metab Dispos 40(1):93-103.
    • (2012) Drug Metab Dispos , vol.40 , Issue.1 , pp. 93-103
    • Schaefer, O.1    Ohtsuki, S.2    Kawakami, H.3    Inoue, T.4    Liehner, S.5    Saito, A.6    Sakamoto, A.7    Ishiguro, N.8    Matsumaru, T.9    Terasaki, T.10    Ebner, T.11
  • 11
    • 77958025244 scopus 로고    scopus 로고
    • Structure and function of the human breast cancer resistance protein (BCRP/ABCG2)
    • Ni Z, Bikadi Z, Rosenberg MF, Mao Q. 2010. Structure and function of the human breast cancer resistance protein (BCRP/ABCG2). Curr Drug Metab 11(7):603-617.
    • (2010) Curr Drug Metab , vol.11 , Issue.7 , pp. 603-617
    • Ni, Z.1    Bikadi, Z.2    Rosenberg, M.F.3    Mao, Q.4
  • 12
    • 0035502455 scopus 로고    scopus 로고
    • Bilateral pharmacokinetic interaction between cyclosporine A and atorvastatin in renal transplant recipients
    • Asberg A, Hartmann A, Fjeldsa E, Bergan S, Holdaas H. 2001. Bilateral pharmacokinetic interaction between cyclosporine A and atorvastatin in renal transplant recipients. Am J Transplant 1(4):382-386.
    • (2001) Am J Transplant , vol.1 , Issue.4 , pp. 382-386
    • Asberg, A.1    Hartmann, A.2    Fjeldsa, E.3    Bergan, S.4    Holdaas, H.5
  • 13
    • 1642523136 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression
    • Hedman M, Neuvonen PJ, Neuvonen M, Holmberg C, Antikainen M. 2004. Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression. Clin Pharmacol Ther 75(1):101-109.
    • (2004) Clin Pharmacol Ther , vol.75 , Issue.1 , pp. 101-109
    • Hedman, M.1    Neuvonen, P.J.2    Neuvonen, M.3    Holmberg, C.4    Antikainen, M.5
  • 19
    • 17844372454 scopus 로고    scopus 로고
    • Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver
    • Merino G, van Herwaarden AE, Wagenaar E, Jonker JW, Schinkel AH. 2005. Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver. Mol Pharmacol 67(5):1765-1771.
    • (2005) Mol Pharmacol , vol.67 , Issue.5 , pp. 1765-1771
    • Merino, G.1    van Herwaarden, A.E.2    Wagenaar, E.3    Jonker, J.W.4    Schinkel, A.H.5
  • 20
    • 0141920354 scopus 로고    scopus 로고
    • Comparing protein abundance and mRNA expression levels on a genomic scale
    • Greenbaum D, Colangelo C, Williams K, Gerstein M. 2003. Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol 4(9):117.
    • (2003) Genome Biol , vol.4 , Issue.9 , pp. 117
    • Greenbaum, D.1    Colangelo, C.2    Williams, K.3    Gerstein, M.4
  • 21
    • 33845790070 scopus 로고    scopus 로고
    • Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: A quantitative analysis
    • Nie L, Wu G, Zhang W. 2006. Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: A quantitative analysis. Genetics 174(4):2229-2243.
    • (2006) Genetics , vol.174 , Issue.4 , pp. 2229-2243
    • Nie, L.1    Wu, G.2    Zhang, W.3
  • 22
    • 83955163683 scopus 로고    scopus 로고
    • Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum
    • Tucker TG, Milne AM, Fournel-Gigleux S, Fenner KS, Coughtrie MW. 2012. Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum. Biochem Pharmacol 83(2):279-285.
    • (2012) Biochem Pharmacol , vol.83 , Issue.2 , pp. 279-285
    • Tucker, T.G.1    Milne, A.M.2    Fournel-Gigleux, S.3    Fenner, K.S.4    Coughtrie, M.W.5
  • 24
    • 58549097067 scopus 로고    scopus 로고
    • Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations
    • Furukawa T, Wakabayashi K, Tamura A, Nakagawa H, Morishima Y, Osawa Y, Ishikawa T. 2009. Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations. Pharm Res 26(2):469-479.
    • (2009) Pharm Res , vol.26 , Issue.2 , pp. 469-479
    • Furukawa, T.1    Wakabayashi, K.2    Tamura, A.3    Nakagawa, H.4    Morishima, Y.5    Osawa, Y.6    Ishikawa, T.7
  • 27
    • 70649110001 scopus 로고    scopus 로고
    • Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin
    • Keskitalo JE, Pasanen MK, Neuvonen PJ, Niemi M. 2009. Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin. Pharmacogenomics 10(10):1617-1624.
    • (2009) Pharmacogenomics , vol.10 , Issue.10 , pp. 1617-1624
    • Keskitalo, J.E.1    Pasanen, M.K.2    Neuvonen, P.J.3    Niemi, M.4
  • 32
    • 77953967726 scopus 로고    scopus 로고
    • ABCG2 421C>A polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma
    • Mizuno T, Terada T, Kamba T, Fukudo M, Katsura T, Nakamura E, Ogawa O, Inui K. 2010. ABCG2 421C>A polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma. Ann Oncol 21(6):1382-1383.
    • (2010) Ann Oncol , vol.21 , Issue.6 , pp. 1382-1383
    • Mizuno, T.1    Terada, T.2    Kamba, T.3    Fukudo, M.4    Katsura, T.5    Nakamura, E.6    Ogawa, O.7    Inui, K.8
  • 35
    • 80051544848 scopus 로고    scopus 로고
    • Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5
    • Kaspera R, Naraharisetti SB, Evangelista EA, Marciante KD, Psaty BM, Totah RA. 2011. Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5. Biochem Pharmacol 82(6):681-691.
    • (2011) Biochem Pharmacol , vol.82 , Issue.6 , pp. 681-691
    • Kaspera, R.1    Naraharisetti, S.B.2    Evangelista, E.A.3    Marciante, K.D.4    Psaty, B.M.5    Totah, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.