Drug-induced trafficking of P-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Noack, Andreas ^a   Noack, Sandra ^b   Hoffmann, Andrea ^b   Maalouf, Katia ^a   Buettner, Manuela ^b   Couraud, Pierre Olivier ^c,d,e   Romero, Ignacio A ^f   Weksler, Babette ^g   Alms, Dana ^a   Römermann, Kerstin ^a   Naim, Hassan Y ^a   Löscher, Wolfgang ^a,h  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c INSTITUT COCHIN   (France)

^d CNRS   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f OPEN UNIVERSITY   (United Kingdom)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

^h CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; CHOLESTEROL; ENHANCED GREEN FLUORESCENT PROTEIN; MITOMYCIN; MULTIDRUG RESISTANCE PROTEIN 1; RHODAMINE 123;

ARTICLE; BRAIN CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; EMBRYO; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; LIPID RAFT; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TRANSPORT;

BLOOD-BRAIN BARRIER; BRAIN; CELL LINE; CHOLESTEROL; ENDOTHELIAL CELLS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MEMBRANE MICRODOMAINS; MITOMYCIN; P-GLYCOPROTEIN; PROTEIN TRANSPORT; RHODAMINE 123;

EID: 84894637029     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088154     Document Type: Article

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