PEGylated carboxymethyl chitosan/calcium phosphate hybrid anionic nanoparticles mediated hTERT siRNA delivery for anticancer therapy

Biomaterials

Volumn 35, Issue 27, 2014, Pages 7978-7991

  Xie, Ying ^a   Qiao, Hongzhi ^a   Su, Zhigui ^a   Chen, Minglei ^a   Ping, Qineng ^a   Sun, Minjie ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anionic nanoparticles; Calcium phosphate; Cancer therapy; HTERT; SiRNA delivery

Indexed keywords

CALCIUM PHOSPHATE; CELL DEATH; GENETIC ENGINEERING; LIPOSOMES; MOLECULAR BIOLOGY; NANOPARTICLES; ONCOLOGY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; RNA; TUMORS;

ANTI-CANCER THERAPIES; CANCER THERAPY; CARBOXYMETHYL CHITOSAN; HTERT; INTRAVENOUS INJECTIONS; REPORTER GENE SILENCING; SELF-ASSEMBLY METHOD; SIRNA DELIVERY;

SYNTHESIS (CHEMICAL);

CALCIUM PHOSPHATE; CHITOSAN; LIPOFECTAMINE; LUCIFERASE; NANOPARTICLE; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE; ANION; CARBOXYMETHYL-CHITOSAN; MESSENGER RNA; TELOMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BALB/C NUDE MOUSE; CANCER THERAPY; CONTROLLED STUDY; ENCAPSULATION; ENDOCYTOSIS; GENE DELIVERY SYSTEM; GENE SILENCING; GENETIC TRANSFECTION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REPORTER GENE; TUMOR GROWTH; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG SCREENING; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETICS; INTRACELLULAR SPACE; LIGHT; LUMINESCENCE; METABOLISM; NEOPLASMS; NUDE MOUSE; PARTICLE SIZE; PATHOLOGY; RADIATION SCATTERING; STATIC ELECTRICITY; SYNTHESIS; TISSUE DISTRIBUTION; ULTRASTRUCTURE;

ANIMALS; ANIONS; APOPTOSIS; CALCIUM PHOSPHATES; CHITOSAN; ENDOCYTOSIS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENE TRANSFER TECHNIQUES; HEP G2 CELLS; HUMANS; INTRACELLULAR SPACE; LIGHT; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE, NUDE; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; RNA, MESSENGER; RNA, SMALL INTERFERING; SCATTERING, RADIATION; STATIC ELECTRICITY; TELOMERASE; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903480647     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.05.068     Document Type: Article

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