Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cells

Acta Biomaterialia

Volumn 9, Issue 7, 2013, Pages 7527-7535

  Sokolova, Viktoriya ^a   Kozlova, Diana ^a   Knuschke, Torben ^b   Buer, Jan ^b   Westendorf, Astrid M ^b   Epple, Matthias ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Calcium phosphate; Endocytosis; Inhibitors; Nanoparticles

Indexed keywords

CALCIUM PHOSPHATE; CELL CULTURE; LANTHANUM COMPOUNDS; MOLECULAR BIOLOGY;

CALCIUM PHOSPHATE NANOPARTICLES; CATIONICS; CELL-BE; CELL/B.E; CELL/BE; HELA CELL; INHIBITOR; LY294002; UPTAKE MECHANISM; WORTMANNIN;

NANOPARTICLES;

2 MORPHOLINO 8 PHENYLCHROMONE; CALCIUM PHOSPHATE; CHLORPROMAZINE; NANOPARTICLE; NOCODAZOLE; NYSTATIN; WORTMANNIN;

ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CULTURE MEDIUM; DRUG CYTOTOXICITY; ENDOCYTOSIS; FLOW CYTOMETRY; HELA CELL; INCUBATION TIME; LYSOSOME; PARTICLE SIZE; PH; PINOCYTOSIS; PRIORITY JOURNAL; ROOM TEMPERATURE;

EID: 84878297703     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.02.034     Document Type: Article

References (41)

1. R. Bausinger, K. von Gersdorff, K. Braeckmans, M. Ogris, E. Wagner, and C. Bräuchle The transport of nanosized gene carriers unraveled by live-cell imaging Angew Chem Int Ed 45 2006 1568 1572
2. H. Laroui, A.L. Theiss, Y. Yan, G. Dalmasso, H.T.T. Nguyen, and S.V. Sitaraman Functional TNF-a gene silencing mediated by polyethyleneimine/TNF-a siRNA nanocomplexes in inflamed colon Biomaterials 32 2011 1218 1228
3. X. Zhang, A. Kovtun, C. Mendoza-Palomares, M. Oulad-Abdelghani, S. Facca, and F. Fioretti SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing Biomaterials 31 2010 6013 6018
4. Y. Cheng, A.C. Samia, J.D.P. Meyers, I. Panagopoulos, B. Fei, and C. Burda Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer J Am Chem Soc 130 2008 10643 10647
5. C. Mayer Nanocapsules as drug delivery systems Int J Artif Organs 28 2005 1163 1171
6. T.L. Doane, and C. Burda The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy Chem Soc Rev 41 2012 2885 2911
7. F.M. Kievit, and M. Zhang Cancer therapy: cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers Adv Mater 23 2011 H209
8. V. Sokolova, and M. Epple Inorganic nanoparticles as carriers of nucleic acids into cells Angew Chem Int Ed 47 2008 1382 1395
9. G. Sahay, D.Y. Alakhova, and A.V. Kabanov Endocytosis of nanomedicines J Control Release 145 2010 182 195
10. V. Sokolova, O. Rotan, J. Klesing, P. Nalbant, J. Buer, and T. Knuschke Calcium phosphate nanoparticles as versatile carrier for small and large molecules across cell membranes J Nanopart Res 14 2012 910
11. I. Canton, and G. Battaglia Endocytosis at the nanoscale Chem Soc Rev 41 2012 2718 2739
12. G.J. Doherty, and H.T. McMahon Mechanisms of endocytosis Ann Rev Biochem 78 2009 857 902
13. P.G. Woodman, and C.E. Futter Multivesicular bodies: co-ordinated progression to maturity Curr Opin Cell Biol 20 2008 408 414
14. C. Greulich, J. Diendorf, T. Simon, G. Eggeler, M. Epple, and M. Köller Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells Acta Biomater 7 2011 347 354
15. L.P. Fernando, P.K. Kandel, J. Yu, J. McNeill, P.C. Ackroyd, and K.A. Christensen Mechanism of cellular uptake of highly fluorescent conjugated polymer nanoparticles Biomacromolecules 11 2010 2675 2682
16. M. Vallet-Regi, and J.M. González-Calbet Calcium phosphates as substitution of bone tissues Prog Solid State Chem 32 2004 1 31
17. S.V. Dorozhkin, and M. Epple Biological and medical significance of calcium phosphates Angew Chem Int Ed 41 2002 3130 3146
18. Y. Cai, and R. Tang Calcium phosphate nanoparticles in biomineralization and biomaterials J Mater Chem 18 2008 3775 3787
19. A. Maitra Calcium-phosphate nanoparticles: second-generation nonviral vectors in gene therapy Expert Rev Mol Diagn 5 2005 893 905
20. Chernousova S, Klesing J, Soklakova N, Epple M. A genetically active nano-calcium phosphate paste for bone substitution, encoding the formation of BMP-7 and VEGF-A. RSC Adv, in press. http://dx.doi.org/10.1039/C3RA23450A.
21. V. Uskokovic, and D.P. Uskokovic Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents J Biomed Mat Res B 96 2011 152 191
22. R. Ramachandran, W. Paul, and C.P. Sharma Synthesis and characterization of PEGylated calcium phosphate nanoparticles for oral insulin delivery J Biomed Mater Res Part B Appl Biomater 88B 2009 41 48
23. F.X. Huber, N. McArthur, L. Heimann, E. Dingeldein, H. Cavey, and X. Palazzi Evaluation of a novel nanocrystalline hydroxyapatite paste Ostim(R) in comparison to Alpha-BSM(R) - more bone ingrowth inside the implanted material with Ostim(R) compared to Alpha BSM(R) BMC Musculoskelet Disord 10 2009 164
24. R. Smeets, M.B. Grosjean, G. Jelitte, M. Heiland, A. Kasaj, and D. Riediger Hydroxyapatite bone substitute (Ostim) in sinus floor elevation. Maxillary sinus floor augmentation: bone regeneration by means of a nanocrystalline in-phase hydroxyapatite (Ostim) Schweiz Monatsschr Zahnmed 118 2008 203 212
25. A.E. Ewence, M. Bootman, H.L. Roderick, J.N. Skepper, G. McCarthy, and M. Epple Calcium phosphate crystals induce cell death in human vascular smooth muscle cells - a potential mechanism in atherosclerotic plaque destabilization Circ Res 103 2008 e28 e32
26. M. Motskin, D.M. Wright, K. Muller, N. Kyle, T.G. Gard, and A.E. Porter Hydroxyapatite nano and microparticles: correlation of particle properties with cytotoxicity and biostability Biomaterials 30 2009 3307 3317
27. S. Neumann, A. Kovtun, I.D. Dietzel, M. Epple, and R. Heumann The use of size-defined DNA-functionalized calcium phosphate nanoparticles to minimise intracellular calcium disturbance during transfection Biomaterials 30 2009 6794 6802
28. F.L. Graham, and A.J. van der Eb A new technique for the assay of infectivity of human adenovirus 5 DNA Virology 52 1973 456 467
29. V. Sokolova, T. Knuschke, J. Buer, A.M. Westendorf, and M. Epple Quantitative determination of the composition of multi-shell calcium phosphate-oligonucleotide nanoparticles and their application for the activation of dendritic cells Acta Biomater 7 2011 4029 4036
30. D. Kozlova, S. Chernousova, T. Knuschke, J. Buer, A.M. Westendorf, and M. Epple Cell targeting by antibody-functionalized calcium phosphate nanoparticles J Mater Chem 22 2012 396 404
31. S.K. Lai, K. Hida, C. Chen, and J. Hanes Characterization of the intracellular dynamics of a non-degradative pathway accessed by polymer nanoparticles J Control Release 125 2008 107 111
32. N.Q. Liu, A.S. Lossinsky, W. Popik, X. Li, C. Gujuluva, and B. Kriederman Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway J Virol 76 2002 6689 6700
33. O. Harush-Frenkel, N. Debotton, S. Benita, and Y. Altschuler Targeting of nanoparticles to the clathrin-mediated endocytic pathway Biochem Biophys Res Commun 353 2007 26 32
34. J. Rejman, V. Oberle, I.S. Zuhorn, and D. Hoekstra Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis Biochem J 377 2004 159 169
35. M.C. Kerr, and R.D. Teasdale Defining macropinocytosis Traffic 10 2009 364 371
36. J. Liu, Z. Diwu, and W.Y. Leung Synthesis and photophysical properties of new fluorinated benzo[c]xanthene dyes as intracellular pH indicators Bioorg Med Chem Lett 11 2001 2903 2905
37. O. Kreft, A.M. Javier, G.B. Sukhorukov, and W.J. Parak Polymer microcapsules as mobile local pH-sensors J Mater Chem 17 2007 4471 4476
38. J. Han, and K. Burgess Fluorescent indicators for intracellular pH Chem Rev 110 2010 2709 2728
39. P.R. Gil, M. Nazarenus, S. Ashraf, and W.J. Parak PH-sensitive capsules as intracellular optical reporters for monitoring lysosomal pH changes upon stimulation Small 8 2012 943 948
40. W. Tong, X. Song, and C. Gao Layer-by-layer assembly of microcapsules and their biomedical applications Chem Soc Rev 41 2012 6103 6124
41. M. Motskin, K.H. Möller, C. Genoud, A.G. Monteith, and J.N. Skepper The sequestration of hydroxyapatite nanoparticles by human monocyte-macrophages in a compartment that allows free diffusion with the extracellular environment Biomaterials 32 2011 9470 9482