메뉴 건너뛰기




Volumn , Issue , 2013, Pages 323-361

An integrated human mammary epithelial cell culture system for studying carcinogenesis and aging

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84903385946     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-62703-634-4_15     Document Type: Chapter
Times cited : (26)

References (112)
  • 9
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens PJ, Tarpey PS, Davis H, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature. 2012;486:400-4.
    • (2012) Nature , vol.486 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davis, H.3
  • 10
    • 0029040101 scopus 로고
    • Developmental and tissue-specific regulation of mouse telomerase and telomere length
    • Prowse KR, Greider CW. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc Natl Acad Sci USA. 1995;92:4818-22.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4818-4822
    • Prowse, K.R.1    Greider, C.W.2
  • 11
    • 33747587608 scopus 로고    scopus 로고
    • Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
    • Gil J, Peters G. Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat Rev Mol Cell Biol. 2006;7:667-77.
    • (2006) Nat Rev Mol Cell Biol. , vol.7 , pp. 667-677
    • Gil, J.1    Peters, G.2
  • 12
    • 0020031585 scopus 로고
    • Metabolism of benzo (a) pyrene by human epithelial and fibroblastic cells: Metabolite patterns and DNA adduct formation
    • Bartley J, Bartholomew JC, Stampfer MR. Metabolism of benzo (a) pyrene by human epithelial and fibroblastic cells: metabolite patterns and DNA adduct formation. J Cell Biochem. 1982;18:135-48.
    • (1982) J Cell Biochem , vol.18 , pp. 135-148
    • Bartley, J.1    Bartholomew, J.C.2    Stampfer, M.R.3
  • 13
    • 0024420188 scopus 로고
    • Effects of transforming growth factor-â on growth of human mammary epithelial cells in culture
    • Hosobuchi M, Stampfer MR. Effects of transforming growth factor-â on growth of human mammary epithelial cells in culture. In Vitro. 1989;25:705-12.
    • (1989) Vitro , vol.25 , pp. 705-712
    • Hosobuchi, M.1    Stampfer, M.R.2
  • 14
    • 0037068753 scopus 로고    scopus 로고
    • Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion
    • Olsen CL, Gardie B, Yaswen P, Stampfer MR. Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion. Oncogene. 2002;21:6328-39.
    • (2002) Oncogene , vol.21 , pp. 6328-6339
    • Olsen, C.L.1    Gardie, B.2    Yaswen, P.3    Stampfer, M.R.4
  • 15
    • 70350223685 scopus 로고    scopus 로고
    • Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells
    • Garbe JC, Bhattacharya S, Merchant B, Bassett E, Swisshelm K, Feiler HS, Wyrobek AJ, Stampfer MR. Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells. Cancer Res. 2009;69:7557-68.
    • (2009) Cancer Res. , vol.69 , pp. 7557-7568
    • Garbe, J.C.1    Bhattacharya, S.2    Merchant, B.3    Bassett, E.4    Swisshelm, K.5    Feiler, H.S.6    Wyrobek, A.J.7    Stampfer, M.R.8
  • 16
    • 79957772521 scopus 로고    scopus 로고
    • TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells
    • Cipriano R, Kan CE, Graham J, Danielpour D, Stampfer M, Jackson MW. TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells. Proc Natl Acad Sci USA. 2011;108:8668-73.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8668-8673
    • Cipriano, R.1    Kan, C.E.2    Graham, J.3    Danielpour, D.4    Stampfer, M.5    Jackson, M.W.6
  • 17
    • 83055182019 scopus 로고    scopus 로고
    • Epigenetic regulation of normal human mammary cell type-specific miRNAs
    • Vrba L, Garbe JC, Stampfer MR, Futscher BW. Epigenetic regulation of normal human mammary cell type-specific miRNAs. Genome Res. 2011;21:2026-37.
    • (2011) Genome Res. , vol.21 , pp. 2026-2037
    • Vrba, L.1    Garbe, J.C.2    Stampfer, M.R.3    Futscher, B.W.4
  • 18
    • 34548288604 scopus 로고    scopus 로고
    • Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis
    • Garbe JC, Holst CR, Bassett E, Tlsty T, Stampfer MR. Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis. Cell Cycle. 2007;6:1927-36.
    • (2007) Cell Cycle , vol.6 , pp. 1927-1936
    • Garbe, J.C.1    Holst, C.R.2    Bassett, E.3    Tlsty, T.4    Stampfer, M.R.5
  • 19
    • 0032537762 scopus 로고    scopus 로고
    • Increased p16INK4a expression with onset of senescence of human mammary epithelial cells and extended growth capacity with inactivation
    • Brenner AJ, Stampfer MR, Aldaz CM. Increased p16INK4a expression with onset of senescence of human mammary epithelial cells and extended growth capacity with inactivation. Oncogene. 1998;17:199-205.
    • (1998) Oncogene , vol.17 , pp. 199-205
    • Brenner, A.J.1    Stampfer, M.R.2    Aldaz, C.M.3
  • 20
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov S, Kozakiewicz K, Holst C, Stampfer MR, Haupt LM, Tlsty T. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature. 2001;409:633-7.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.1    Kozakiewicz, K.2    Holst, C.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.6
  • 21
    • 0020363856 scopus 로고
    • Cholera toxin stimulation of human mammary epithelial cells in culture
    • Stampfer MR. Cholera toxin stimulation of human mammary epithelial cells in culture. In Vitro. 1982;18:531-7.
    • (1982) Vitro , vol.18 , pp. 531-537
    • Stampfer, M.R.1
  • 22
    • 0345178412 scopus 로고
    • Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract
    • Hammond SL, Ham RG, Stampfer MR. Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc Natl Acad Sci USA. 1984;81:5435-9.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5435-5439
    • Hammond, S.L.1    Ham, R.G.2    Stampfer, M.R.3
  • 23
    • 0006312841 scopus 로고
    • Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene
    • Stampfer MR, Bartley JC. Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene. Proc Natl Acad Sci USA. 1985;82:2394-8.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2394-2398
    • Stampfer, M.R.1    Bartley, J.C.2
  • 24
    • 0041353457 scopus 로고    scopus 로고
    • Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines
    • Stampfer MR, Garbe J, Nijjar T, Wigington D, Swisshelm K, Yaswen P. Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines. Oncogene. 2003;22:5238-51.
    • (2003) Oncogene , vol.22 , pp. 5238-5251
    • Stampfer, M.R.1    Garbe, J.2    Nijjar, T.3    Wigington, D.4    Swisshelm, K.5    Yaswen, P.6
  • 25
    • 67449158992 scopus 로고    scopus 로고
    • Step-wise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization
    • Novak P, Jensen TJ, Garbe JC, Stampfer MR, Futscher BW. Step-wise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization. Cancer Res. 2009;67:5251-8.
    • (2009) Cancer Res. , vol.67 , pp. 5251-5258
    • Novak, P.1    Jensen, T.J.2    Garbe, J.C.3    Stampfer, M.R.4    Futscher, B.W.5
  • 26
    • 0029901708 scopus 로고    scopus 로고
    • High frequency of aberrant p16 INK4A expression in human breast cancer
    • Geradts J, Wilson PA. High frequency of aberrant p16 INK4A expression in human breast cancer. Am J Pathol. 1996;149:15-20.
    • (1996) Am J Pathol. , vol.149 , pp. 15-20
    • Geradts, J.1    Wilson, P.A.2
  • 27
    • 0029666504 scopus 로고    scopus 로고
    • Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: Relationship of dysfunction to immortality and neoplasia
    • Loughran O, Malliri A, Owens D, Gallimore PH, Stanley MA, Ozanne B, Frame MC, Parkinson EK. Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: relationship of dysfunction to immortality and neoplasia. Oncogene. 1996;13:561-8.
    • (1996) Oncogene , vol.13 , pp. 561-568
    • Loughran, O.1    Malliri, A.2    Owens, D.3    Gallimore, P.H.4    Stanley, M.A.5    Ozanne, B.6    Frame, M.C.7    Parkinson, E.K.8
  • 32
    • 0030609861 scopus 로고    scopus 로고
    • Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
    • Brown JP, Wei W, Sedivy JM. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science. 1997;277:831-4.
    • (1997) Science , vol.277 , pp. 831-834
    • Brown, J.P.1    Wei, W.2    Sedivy, J.M.3
  • 33
    • 0036288508 scopus 로고    scopus 로고
    • A two-stage, p16INK4a- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
    • Rheinwald JG, Hahn WC, Ramsey MR, Wu JY, Guo Z, Tsao H, De Luca M, Catricala C, O'Toole KM. A two-stage, p16INK4a- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol Cell Biol. 2002;22:5157-72.
    • (2002) Mol Cell Biol. , vol.22 , pp. 5157-5172
    • Rheinwald, J.G.1    Hahn, W.C.2    Ramsey, M.R.3    Wu, J.Y.4    Guo, Z.5    Tsao, H.6    De Luca, M.7    Catricala, C.8    O'Toole, K.M.9
  • 34
    • 0041438614 scopus 로고    scopus 로고
    • A P53-dependent, telomereindependent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development
    • Evans RJ, Wyllie FS, Wynford-Thomas D, Kipling D, Jones CJ. A P53-dependent, telomereindependent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development. Cancer Res. 2003;63:4854-61.
    • (2003) Cancer Res. , vol.63 , pp. 4854-4861
    • Evans, R.J.1    Wyllie, F.S.2    Wynford-Thomas, D.3    Kipling, D.4    Jones, C.J.5
  • 36
    • 26944472376 scopus 로고    scopus 로고
    • Telomere dysfunction drives chromosomal instability in human mammary epithelial cells
    • Soler D, Genesca A, Arnedo G, Egozcue J, Tusell L. Telomere dysfunction drives chromosomal instability in human mammary epithelial cells. Genes Chromosomes Cancer. 2005;44:339-50.
    • (2005) Genes Chromosomes Cancer , vol.44 , pp. 339-350
    • Soler, D.1    Genesca, A.2    Arnedo, G.3    Egozcue, J.4    Tusell, L.5
  • 37
    • 3342972121 scopus 로고    scopus 로고
    • Does a sentinel or a subset of short telomeres determine replicative senescence?
    • Zou Y, Sfeir A, Gryaznov SM, Shay JW, Wright WE. Does a sentinel or a subset of short telomeres determine replicative senescence? Mol Biol Cell. 2004;15:3709-18.
    • (2004) Mol Biol Cell , vol.15 , pp. 3709-3718
    • Zou, Y.1    Sfeir, A.2    Gryaznov, S.M.3    Shay, J.W.4    Wright, W.E.5
  • 39
    • 0031041774 scopus 로고    scopus 로고
    • Analysis of telomerase activity in breast cancer: Positive detection at the in situ breast carcinoma stage
    • Bednarek A, Sahin A, Brenner AJ, Johnston DA, Aldaz CM. Analysis of telomerase activity in breast cancer: positive detection at the in situ breast carcinoma stage. Clin Cancer Res. 1997;3:11-6.
    • (1997) Clin Cancer Res. , vol.3 , pp. 11-16
    • Bednarek, A.1    Sahin, A.2    Brenner, A.J.3    Johnston, D.A.4    Aldaz, C.M.5
  • 43
    • 84929866410 scopus 로고    scopus 로고
    • Dramatic telomere shortening occurs in breast luminal epithelial cells in subsets of non-malignant, normal-appearing lobules and small ducts: A potential early molecular mechanism underlying breast tumorigenesis
    • Meeker AK, Beckman-Hicks JL, Argani P, De Marzo AM. Dramatic telomere shortening occurs in breast luminal epithelial cells in subsets of non-malignant, normal-appearing lobules and small ducts: a potential early molecular mechanism underlying breast tumorigenesis. Proc Am Assoc Cancer Res. 2003;44:182.
    • (2003) Proc Am Assoc Cancer Res. , vol.44 , pp. 182
    • Meeker, A.K.1    Beckman-Hicks, J.L.2    Argani, P.3    De Marzo, A.M.4
  • 47
    • 81155148160 scopus 로고    scopus 로고
    • Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response
    • Sherman MY, Meng L, Stampfer MR, Gabai VL, Yaglom JA. Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response. Aging Cell. 2011;10(6):949-61.
    • (2011) Aging Cell , vol.10 , Issue.6 , pp. 949-961
    • Sherman, M.Y.1    Meng, L.2    Stampfer, M.R.3    Gabai, V.L.4    Yaglom, J.A.5
  • 48
    • 0019172106 scopus 로고
    • Growth of normal human mammary epithelial cells in culture
    • Stampfer MR, Hallowes R, Hackett AJ. Growth of normal human mammary epithelial cells in culture. In Vitro. 1980;16:415-25.
    • (1980) Vitro , vol.16 , pp. 415-425
    • Stampfer, M.R.1    Hallowes, R.2    Hackett, A.J.3
  • 49
    • 84875797871 scopus 로고    scopus 로고
    • Processing of human reduction mammoplasty and mastectomy tissues for cell culture
    • LaBarge MA, Garbe JC, Stampfer MR. Processing of human reduction mammoplasty and mastectomy tissues for cell culture. J Vis Exp. 2013;71:e50011.
    • (2013) J Vis Exp , vol.71 , pp. e50011
    • La Barge, M.A.1    Garbe, J.C.2    Stampfer, M.R.3
  • 50
    • 0022388785 scopus 로고
    • Isolation and growth of human mammary epithelial cells
    • Stampfer MR. Isolation and growth of human mammary epithelial cells. J Tissue Cult Methods. 1985;9:107-16.
    • (1985) J Tissue Cult Methods , vol.9 , pp. 107-116
    • Stampfer, M.R.1
  • 51
    • 0024306070 scopus 로고
    • Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: Relation to in vivo phenotypes and influence of medium
    • Taylor-Papadimitriou J, Stampfer MR, Bartek J, Lane EB, Lewis A. Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium. J Cell Sci. 1989;94:403-13.
    • (1989) J Cell Sci. , vol.94 , pp. 403-413
    • Taylor-Papadimitriou, J.1    Stampfer, M.R.2    Bartek, J.3    Lane, E.B.4    Lewis, A.5
  • 56
    • 0036726312 scopus 로고    scopus 로고
    • Beta4 Integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
    • Weaver VM, Lelievre S, Lakins JN, Chrenek MA, Jones JC, Giancotti F, Werb Z, Bissell MJ. beta4 Integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002;2:205-16.
    • (2002) Cancer Cell , vol.2 , pp. 205-216
    • Weaver, V.M.1    Lelievre, S.2    Lakins, J.N.3    Chrenek, M.A.4    Jones, J.C.5    Giancotti, F.6    Werb, Z.7    Bissell, M.J.8
  • 59
    • 0029968012 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 alleviates a proliferative block in early passage human mammary epithelial cells
    • Foster SA, Galloway DA. Human papillomavirus type 16 E7 alleviates a proliferative block in early passage human mammary epithelial cells. Oncogene. 1996;12:1773-9.
    • (1996) Oncogene , vol.12 , pp. 1773-1779
    • Foster, S.A.1    Galloway, D.A.2
  • 61
    • 0021824011 scopus 로고
    • Factors influencing benzo (a) pyrene metabolism in human mammary epithelial cells in culture
    • Bartley JC, Stampfer MR. Factors influencing benzo (a) pyrene metabolism in human mammary epithelial cells in culture. Carcinogenesis. 1985;6:1017-22.
    • (1985) Carcinogenesis , vol.6 , pp. 1017-1022
    • Bartley, J.C.1    Stampfer, M.R.2
  • 64
    • 33846587923 scopus 로고    scopus 로고
    • The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies
    • Siziopikou KP, Cobleigh M. The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies. Breast. 2007;16:104-7.
    • (2007) Breast , vol.16 , pp. 104-107
    • Siziopikou, K.P.1    Cobleigh, M.2
  • 66
    • 0024149738 scopus 로고
    • Human mammary epithelial cells in culture: Differentiation and transformation
    • Stampfer MR, Bartley JC. Human mammary epithelial cells in culture: differentiation and transformation. Cancer Treat Res. 1988;40:1-24.
    • (1988) Cancer Treat Res. , vol.40 , pp. 1-24
    • Stampfer, M.R.1    Bartley, J.C.2
  • 69
    • 0027314750 scopus 로고
    • Expression and stability of p53 protein in normal human mammary epithelial cells
    • Delmolino L, Band H, Band V. Expression and stability of p53 protein in normal human mammary epithelial cells. Carcinogenesis. 1993;14:827-32.
    • (1993) Carcinogenesis , vol.14 , pp. 827-832
    • Delmolino, L.1    Band, H.2    Band, V.3
  • 71
    • 0037380886 scopus 로고    scopus 로고
    • Methylation of p16 (INK4a) promoters occurs in vivo in histologically normal human mammary epithelia
    • Holst CR, Nuovo GJ, Esteller M, Chew K, Baylin SB, Herman JG, Tlsty TD. Methylation of p16 (INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Res. 2003;63:1596-601.
    • (2003) Cancer Res. , vol.63 , pp. 1596-1601
    • Holst, C.R.1    Nuovo, G.J.2    Esteller, M.3    Chew, K.4    Baylin, S.B.5    Herman, J.G.6    Tlsty, T.D.7
  • 73
    • 0030065440 scopus 로고    scopus 로고
    • Immortalization of human mammary epithelial cells transfected with mutant p53 (273his)
    • Gollahon LS, Shay JW. Immortalization of human mammary epithelial cells transfected with mutant p53 (273his). Oncogene. 1996;12:715-25.
    • (1996) Oncogene , vol.12 , pp. 715-725
    • Gollahon, L.S.1    Shay, J.W.2
  • 76
    • 0037687519 scopus 로고    scopus 로고
    • Human epithelial cell immortalization as a step in carcinogenesis
    • Stampfer MR, Yaswen P. Human epithelial cell immortalization as a step in carcinogenesis. Cancer Lett. 2003;194:199-208.
    • (2003) Cancer Lett , vol.194 , pp. 199-208
    • Stampfer, M.R.1    Yaswen, P.2
  • 78
    • 0035860140 scopus 로고    scopus 로고
    • Tumour markers in breast carcinoma correlate with grade rather than with invasiveness
    • Warnberg F, Nordgren H, Bergkvist L, Holmberg L. Tumour markers in breast carcinoma correlate with grade rather than with invasiveness. Br J Cancer. 2001;85:869-74.
    • (2001) Br J Cancer , vol.85 , pp. 869-874
    • Warnberg, F.1    Nordgren, H.2    Bergkvist, L.3    Holmberg, L.4
  • 82
    • 78650599928 scopus 로고    scopus 로고
    • What is the malignant nature of human ductal carcinoma in situ?
    • Espina V, Liotta LA. What is the malignant nature of human ductal carcinoma in situ? Nat Rev Cancer. 2011;11:68-75.
    • (2011) Nat Rev Cancer , vol.11 , pp. 68-75
    • Espina, V.1    Liotta, L.A.2
  • 83
    • 0030668750 scopus 로고    scopus 로고
    • Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells
    • Stampfer MR, Bodnar A, Garbe J, Wong M, Pan A, Villeponteau B, Yaswen P. Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells. Mol Biol Cell. 1997;8:2391-405.
    • (1997) Mol Biol Cell , vol.8 , pp. 2391-2405
    • Stampfer, M.R.1    Bodnar, A.2    Garbe, J.3    Wong, M.4    Pan, A.5    Villeponteau, B.6    Yaswen, P.7
  • 84
    • 0042771339 scopus 로고    scopus 로고
    • Immortal transformation and telomerase reactivation of human mammary epithelial cells in culture
    • Mattson M, Pandita T, editors, Amsterdam: Elsevier
    • Stampfer MR, Yaswen P. Immortal transformation and telomerase reactivation of human mammary epithelial cells in culture. In: Mattson M, Pandita T, editors. Telomerase, aging and disease, vol. 8. Amsterdam: Elsevier; 2001. p. 103-30.
    • (2001) Telomerase, Aging and Disease , vol.8 , pp. 103-130
    • Stampfer, M.R.1    Yaswen, P.2
  • 85
    • 0035866390 scopus 로고    scopus 로고
    • The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells
    • Nonet G, Stampfer MR, Chin K, Gray JW, Collins CC, Yaswen P. The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells. Cancer Res. 2001;61:1250-4.
    • (2001) Cancer Res. , vol.61 , pp. 1250-1254
    • Nonet, G.1    Stampfer, M.R.2    Chin, K.3    Gray, J.W.4    Collins, C.C.5    Yaswen, P.6
  • 86
    • 0035836727 scopus 로고    scopus 로고
    • Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A (-) human mammary epithelial cells
    • Stampfer MR, Garbe J, Levine G, Lichtsteiner S, Vasserot AP, Yaswen P. Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A (-) human mammary epithelial cells. Proc Natl Acad Sci USA. 2001;98:4498-503.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4498-4503
    • Stampfer, M.R.1    Garbe, J.2    Levine, G.3    Lichtsteiner, S.4    Vasserot, A.P.5    Yaswen, P.6
  • 87
    • 0033118908 scopus 로고    scopus 로고
    • Viral oncogenes accelerate conversion to immortality of cultured human mammary epithelial cells
    • Garbe J, Wong M, Wigington D, Yaswen P, Stampfer MR. Viral oncogenes accelerate conversion to immortality of cultured human mammary epithelial cells. Oncogene. 1999;18:2169-80.
    • (1999) Oncogene , vol.18 , pp. 2169-2180
    • Garbe, J.1    Wong, M.2    Wigington, D.3    Yaswen, P.4    Stampfer, M.R.5
  • 88
    • 0032589743 scopus 로고    scopus 로고
    • P57/KIP2 loss of heterozygosity and expression during immortal conversion of human mammary epithelial cells
    • Nijjar T, Wigington D, Garbe JC, Waha A, Stampfer MR, Yaswen P. p57/KIP2 loss of heterozygosity and expression during immortal conversion of human mammary epithelial cells. Cancer Res. 1999;59:5112-8.
    • (1999) Cancer Res. , vol.59 , pp. 5112-5118
    • Nijjar, T.1    Wigington, D.2    Garbe, J.C.3    Waha, A.4    Stampfer, M.R.5    Yaswen, P.6
  • 89
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • Van Steensel B, De Lange T. Control of telomere length by the human telomeric protein TRF1. Nature. 1997;385:740-3.
    • (1997) Nature , vol.385 , pp. 740-743
    • Van Steensel, B.1    De Lange, T.2
  • 90
    • 0024559370 scopus 로고
    • Chromosome analyses of human mammary epithelial cells at stages of chemically-induced transformation progression to immortality
    • Walen K, Stampfer MR. Chromosome analyses of human mammary epithelial cells at stages of chemically-induced transformation progression to immortality. Cancer Genet Cytogenet. 1989;37:249-61.
    • (1989) Cancer Genet Cytogenet , vol.37 , pp. 249-261
    • Walen, K.1    Stampfer, M.R.2
  • 91
    • 0027535320 scopus 로고
    • TGFα induction of extracellular matrix associated proteins in normal and transformed human mammary epithelial cells in culture is independent of growth effects
    • Stampfer MR, Yaswen P, Alhadeff M, Hosoda J. TGFα induction of extracellular matrix associated proteins in normal and transformed human mammary epithelial cells in culture is independent of growth effects. J Cell Physiol. 1993;155:210-21.
    • (1993) J Cell Physiol. , vol.155 , pp. 210-221
    • Stampfer, M.R.1    Yaswen, P.2    Alhadeff, M.3    Hosoda, J.4
  • 94
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science. 2008;319:1352-5.
    • (2008) Science , vol.319 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 95
    • 69249229528 scopus 로고    scopus 로고
    • Telomere length regulation: Coupling DNA end processing to feedback regulation of telomerase
    • Shore D, Bianchi A. Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase. EMBO J. 2009;28:2309-22.
    • (2009) EMBO J , vol.28 , pp. 2309-2322
    • Shore, D.1    Bianchi, A.2
  • 96
    • 84863641682 scopus 로고    scopus 로고
    • Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes
    • Aubert G, Baerlocher GM, Vulto I, Poon SS, Lansdorp PM. Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes. PLoS Genet. 2012;8:e1002696.
    • (2012) PLoS Genet , vol.8 , pp. e1002696
    • Aubert, G.1    Baerlocher, G.M.2    Vulto, I.3    Poon, S.S.4    Lansdorp, P.M.5
  • 97
    • 0028906841 scopus 로고
    • Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand-dependent transformed phenotype
    • Frittitta L, Vigneri R, Stampfer MR, Goldfine ID. Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand-dependent transformed phenotype. J Cell Biochem. 1995;57:666-9.
    • (1995) J Cell Biochem , vol.57 , pp. 666-669
    • Frittitta, L.1    Vigneri, R.2    Stampfer, M.R.3    Goldfine, I.D.4
  • 100
    • 78149467427 scopus 로고    scopus 로고
    • Regulation of C/EBPbeta1 by Ras in mammary epithelial cells and the role of C/EBPbeta1 in oncogene-induced senescence
    • Atwood AA, Sealy L. Regulation of C/EBPbeta1 by Ras in mammary epithelial cells and the role of C/EBPbeta1 in oncogene-induced senescence. Oncogene. 2010;29:6004-15.
    • (2010) Oncogene , vol.29 , pp. 6004-6015
    • Atwood, A.A.1    Sealy, L.2
  • 101
    • 79952121979 scopus 로고    scopus 로고
    • Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
    • Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci USA. 2011;108:1397-402.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1397-1402
    • Iliopoulos, D.1    Hirsch, H.A.2    Wang, G.3    Struhl, K.4
  • 102
    • 84857120037 scopus 로고    scopus 로고
    • Outgrowth of single oncogene-expressing cells from suppressive epithelial environments
    • Leung CT, Brugge JS. Outgrowth of single oncogene-expressing cells from suppressive epithelial environments. Nature. 2012;482:410-3.
    • (2012) Nature , vol.482 , pp. 410-413
    • Leung, C.T.1    Brugge, J.S.2
  • 105
    • 84860550520 scopus 로고    scopus 로고
    • Progressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cells
    • Pampalona J, Frias C, Genesca A, Tusell L. Progressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cells. PLoS Genet. 2012;8:e1002679.
    • (2012) PLoS Genet , vol.8 , pp. e1002679
    • Pampalona, J.1    Frias, C.2    Genesca, A.3    Tusell, L.4
  • 107
    • 0028227197 scopus 로고
    • A novel inhibitor of cyclin-cdk activity detected in transforming growth factor â-arrested epithelial cells
    • Slingerland JM, Hengst L, Pan C-H, Alexander D, Stampfer MR, Reed SI. A novel inhibitor of cyclin-cdk activity detected in transforming growth factor â-arrested epithelial cells. Mol Cell Biol. 1994;14:3683-94.
    • (1994) Mol Cell Biol. , vol.14 , pp. 3683-3694
    • Slingerland, J.M.1    Hengst, L.2    Pan, C.-H.3    Alexander, D.4    Stampfer, M.R.5    Reed, S.I.6
  • 108
    • 0030974040 scopus 로고    scopus 로고
    • TGF-β stabilizes p15INK4B protein, increases p15INK4B/cdk4 complexes and inhibits cyclin D1-cdk4 association in human mammary epithelial cells
    • Sandhu C, Garbe J, Bhattacharya N, Daksis JI, Pan C-H, Yaswen P, Koh J, Slingerland JM, Stampfer MR. TGF-β stabilizes p15INK4B protein, increases p15INK4B/cdk4 complexes and inhibits cyclin D1-cdk4 association in human mammary epithelial cells. Mol Cell Biol. 1997;17:2458-67.
    • (1997) Mol Cell Biol. , vol.17 , pp. 2458-2467
    • Sandhu, C.1    Garbe, J.2    Bhattacharya, N.3    Daksis, J.I.4    Pan, C.-H.5    Yaswen, P.6    Koh, J.7    Slingerland, J.M.8    Stampfer, M.R.9
  • 109
    • 0038724672 scopus 로고    scopus 로고
    • Targeting the TGF beta signaling network in human neoplasia
    • Dumont N, Arteaga CL. Targeting the TGF beta signaling network in human neoplasia. Cancer Cell. 2003;3:531-6.
    • (2003) Cancer Cell , vol.3 , pp. 531-536
    • Dumont, N.1    Arteaga, C.L.2
  • 110
    • 33750069029 scopus 로고    scopus 로고
    • Escaping from the TGFbeta anti-proliferative control
    • Seoane J. Escaping from the TGFbeta anti-proliferative control. Carcinogenesis. 2006;27:2148-56.
    • (2006) Carcinogenesis , vol.27 , pp. 2148-2156
    • Seoane, J.1
  • 112
    • 2142658985 scopus 로고    scopus 로고
    • Molecular evolutionary patterns in breast cancer
    • Shackney SE, Silverman JF. Molecular evolutionary patterns in breast cancer. Adv Anat Pathol. 2003;10:278-90.
    • (2003) Adv Anat Pathol. , vol.10 , pp. 278-290
    • Shackney, S.E.1    Silverman, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.