Progressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cells

PLoS Genetics

Volumn 8, Issue 4, 2012, Pages

  Pampalona, Judit ^a,b   Frías, Cristina ^a,c   Genescà, Anna ^a   Tusell, Laura ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; TELOMERASE; ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ISOENZYME; TARTRATE-RESISTANT ACID PHOSPHATASE; TERT PROTEIN, HUMAN;

ANAPHASE; ARTICLE; BIOACCUMULATION; BREAST EPITHELIUM; CELL DIVISION; CELL FUNCTION; CELL NUCLEUS; CELL POPULATION; CHROMATIN STRUCTURE; CHROMOSOME DISORDER; CONTROLLED STUDY; CYTOKINESIS; CYTOPLASM; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MOLECULAR IMAGING; PHENOTYPE; POLYPLOIDY; TELOMERE; TETRAPLOIDY; TUMOR SUPPRESSOR GENE; WILD TYPE; CELL LINE; CHROMATIN; CHROMOSOMAL INSTABILITY; CYTOLOGY; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; GENETICS; MAMMARY GLAND; METABOLISM; PATHOLOGY; TELOMERE SHORTENING;

ACID PHOSPHATASE; ANAPHASE; BLEOMYCIN; CELL LINE; CHROMATIN; CHROMOSOMAL INSTABILITY; CYTOKINESIS; DNA BREAKS, DOUBLE-STRANDED; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; ISOENZYMES; MAMMARY GLANDS, HUMAN; POLYPLOIDY; TELOMERASE; TELOMERE; TELOMERE SHORTENING;

EID: 84860550520     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002679     Document Type: Article

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