Trifluoperazine rescues human dopaminergic cells from wild-type α-synuclein-induced toxicity

Neurobiology of Aging

Volumn 35, Issue 7, 2014, Pages 1700-1711

  Höllerhage, Matthias ^a,b,c   Goebel, Joachim N ^c   de Andrade, Anderson ^a,c   Hildebrandt, Tobias ^d   Dolga, Amalia ^c   Culmsee, Carsten ^c   Oertel, Wolfgang H ^c   Hengerer, Bastian ^d   Höglinger, Günter U ^a,b,c  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Alpha synuclein; Autophagy; Neurodegeneration; Neuroprotection; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; SMALL INTERFERING RNA; TRIFLUOPERAZINE;

ADENOVIRUS; ARTICLE; CELL ACTIVATION; CELL DEATH; CELL DIFFERENTIATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; GENE TARGETING; HUMAN; HUMAN CELL; LYSOSOME; MACROAUTOPHAGY; MITOSIS; NERVE DEGENERATION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ALPHA-SYNUCLEIN; AUTOPHAGY; NEURODEGENERATION; NEUROPROTECTION; PARKINSON'S DISEASE;

ALPHA-SYNUCLEIN; ANTIPSYCHOTIC AGENTS; AUTOPHAGY; CELLS, CULTURED; DOPAMINERGIC NEURONS; HUMANS; LEWY BODIES; MOLECULAR TARGETED THERAPY; PARKINSON DISEASE; TRIFLUOPERAZINE;

EID: 84903372510     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.01.027     Document Type: Article

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