Aggregation of αsynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons

Acta Neuropathologica

Volumn 123, Issue 5, 2012, Pages 671-683

  Taschenberger, Grit ^a   Garrido, Manuel ^a,c   Tereshchenko, Yuliya ^a   Bähr, Mathias ^a   Zweckstetter, Markus ^b   Kügler, Sebastian ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Synuclein; Adeno associated virus; Aggregation; Parkinson's disease; Substantia nigra

Indexed keywords

ALPHA SYNUCLEIN; PARVOVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DISEASE COURSE; DOPAMINERGIC NERVE CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; MESENCEPHALON; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; STRIATE CORTEX; SUBSTANTIA NIGRA;

AGE FACTORS; ALPHA-SYNUCLEIN; ANALYSIS OF VARIANCE; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; MUTATION; NEURODEGENERATIVE DISEASES; NEUROFIBRILLARY TANGLES; NEURONS; PROTEIN KINASES; RATS; SUBSTANTIA NIGRA; TRANSDUCTION, GENETIC; TRANSFECTION; TYROSINE 3-MONOOXYGENASE; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 84862672217     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0926-8     Document Type: Article

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