Zinc: The metal of life

Comprehensive Reviews in Food Science and Food Safety

Volumn 13, Issue 4, 2014, Pages 358-376

  Kaur, Kuljeet ^a   Gupta, Rajiv ^a   Saraf, Shubhini A ^b   Saraf, Shailendra K ^c  

^a BABU BANARASI DAS NATIONAL INSTITUTE OF TECHNOLOGY AND MANAGEMENT   (India)

^b BABASAHEB BHIMRAO AMBEDKAR UNIVERSITY   (India)

^c Babu Banarasi Das Northern India Institute of Technology   (India)

Author keywords

Antimicrobial; Enzyme; Food science; Nutrition; Zinc

Indexed keywords

ASPERGILLUS; BIOINFORMATICS; BIOLOGICAL SYSTEMS; ENZYMES; NUTRITION; PHYSIOLOGY;

ANTIMICROBIAL; ASPERGILLUS NIGER; BIOLOGICAL FUNCTIONS; CELLULAR COMPONENTS; ENZYMATIC CATALYSIS; FOOD SCIENCE; PHYSIOLOGICAL FUNCTIONS; ZINC-BINDING SITES;

ZINC;

EID: 84902977148     PISSN: None     EISSN: 15414337     Source Type: Journal    
DOI: 10.1111/1541-4337.12067     Document Type: Review

References (293)

1. Ackland ML, Michalczyk A. 2006. Zinc deficiency and its inherited disorders-a review. Genes Nutr 1:41-9.
2. Adachi Y, Yoshida J, Kodera Y, Kiss T, Jakusch T, Enyedy EA, Yoshikawa Y, Sakurai H. 2006. Oral administration of a zinc complex improves type 2 diabetes and metabolic syndromes. Biochem Biophys Res Commun 351:165-70.
3. Aiken S, Horn NM, Saunders NR. 1992. Effects of histidine on tissue zinc distribution in rats. Biometals 5:235-43.
4. Ali P, Hanachi P, Golkhoo S. 2009. Effect of zinc supplement on the upper and lower trunk strength on athletics women. Res J Intern Stud 9:59-63.
5. Amani R, Saeidi S, Nazari Z, Nematpour S. 2010. Correlation between dietary zinc intakes and its serum levels with depression scales in young female students. Biol Trace Elem Res 137:150-8.
6. Anderson RA, Roussel AM, Zouari N, Mahjoub S, Matheau JM, Kerkeni A. 2001. Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus. J Am Coll Nutr 20:212-8.
7. Andreini C, Bertini I. 2012. A bioinformatics view of zinc enzymes. J Inorg Biochem 111:150-6.
8. Andrews M, Gallagher-Allred C. 1999. The role of zinc in wound healing. Adv Wound Care 12:137-8.
9. Archana J, Navaneethan M, Ponnusamy S, Hayakawa Y, Muthamizhchelvan C. 2011.Organic molecules passivated manganese doped zinc selenide quantum dots and its properties. Appl Surf Sci 257:7699-703.
10. Arslantas A, Devrim AK, Kaya N, Necefoglu H. 2006. Studies on the interaction between zinc-hydroxybenzoite complex and genomic DNA. Intl J Mol Sci 7:111-8.
11. Arvanitidou V, Voskaki I, Tripsianis G, Athanasopoulou H, Tsalkidis A, Filippidis S, Schulpis K, Androulakis I. 2007. Serum copper and zinc concentrations in healthy children aged 3-14 years in Greece. Biol Trace Elem Res 115:1-12.
12. ATSDR: Toxicological Profile for Zinc [Internet]. United States: Government; 2005. Available from: http://www.atsdr.cdc.gov/toxprofiles/tp60.html. Accessed 2012 January 7.
13. Augustyniak M, Babczynska A, Augustyniak M. 2011. Oxidative stress in newly hatched chorthippus brunneus-the effects of zinc treatment during diapause depending on the female's age and its origins. Comp Biochem Physiol C Sep 154(3):172-9.
14. Azizzadeh M, Mohri M, Seifi HA. 2005. Effect of oral zinc supplementation on hematology, serum biochemistry, performance, and health in neonatal dairy calves. Comp Clin Path 14:67-71.
15. Bakan R, Birmingham CL, Aeberhardt L, Goldner EM. 1993. Dietary zinc intake of vegetarian and nonvegetarian patients with anorexia nervosa. Intl J Eat Disord 13:229-33.
16. Baqui AH, Black RE, Fischer Walker CL, Arifeen S, Zaman K, Yunus M, Wahed MA, Caulfield LE. 2006. Zinc supplementation and serum zinc during diarrhea. Indian J Pediatr 73:493-7.
17. Baum MK, Shor-Posner G, Campa A. 2000. Zinc status in human immunodeficiency virus infection. J Nutr 130(5):1421S-3S.
18. Bedwal RS, Bahuguna A.1994. Zinc, copper and selenium in reproduction. Experientia 50:626-40.
19. Beskonakli E, Palaoglu S, Aksaray S, Alanoglu G, Turhan T, Taskin Y. 2001. Effect of pinealectomy on immune parameters in rats with Staphylococcus aureus infection. Neurosurg Rev 24:26-30.
20. Beutler K, Pankewycz O, Brautigan DL. 1998. Equivalent uptake of organic and inorganic zinc by monkey kidney fibroblasts, human intestinal epithelial cells, or perfused mouse intestine. Biol Trace Elem Res 61:19-31.
21. Bhatnagar S, Natchu UC. 2004. Zinc in child health and disease. Indian J Pediatr 71:991-5.
22. Bjorklund NL, Sadagoparamanujam VM, Taglialatela G. 2012. Selective, quantitative measurement of releasable synaptic zinc in human autopsy hippocampal brain tissue from Alzheimer's disease patients. J Neurosci Meth 203:146-51.
23. Bocchini SF, Habr-Gama A, Kiss DR, Imperiale AR, Araujo SEA. 2003. Gluteal and perianal hidradenitis suppurativa. Surgical treatment by wide excision. Dis Colon Rectum 46(7):944-9.
24. Bode JC, Hanisch P, Henning H, Koenig W, Richter FW, Bode C. 1988. Hepatic zinc content in patients with various stages of alcoholic liver disease and in patients with chronic active and chronic persistent hepatitis. Hepatology 8:1605-9.
25. Bolkent S, Yanardag R, Bolkent S, Mutlu O, Yildirim S, Kangawa K, Minegishi Y, Suzuki H. 2006. The effect of zinc supplementation on ghrelin-immunoreactive cells and lipid parameters in gastrointestinal tissue of streptozotocin-induced female diabetic rats. Mol Cell Biochem 286:77-85.
26. Bonomini M. 1993. Effects of zinc supplementation in chronic haemodialysis patients. Nephrol Dial Transpl 8:1166-8.
27. Boyd D, Li H, Tanner DA, Towler MR, Wall JG. 2006. The antibacterial effects of zinc ion migration from zinc-based glass polyalkenoate cements. J Mater Sci: Mater Med 17:489-94.
28. Brand IA, Kleineke J. 1996. Intracellular zinc movement and its effect on the carbohydrate metabolism of isolated rat hepatocytes. J Biol Chem 271:1941-9.
29. Braun O, Heilmann K, Pauli W, Rossner JA, Bergmann KE. 1976. Acrodermatitis enteropathica: recent findings concerning clinical features, pathogenesis, diagnosis and therapy. Eur J Pediatr 121(4):247-61.
30. Breskin MW, Worthington-Roberts BS, Knopp RH, Brown Z, Plovie B, Mottet NK, Mills JL. 1983. First trimester serum zinc concentrations in human pregnancy. Am J Clin Nutr 38:943-53.
31. Brewer GJ, Johnson VD, Dick RD, Hedera P, Fink JK, Kluin KJ. 2000. Treatment of Wilson's disease with zinc. XVII: treatment during pregnancy. Hepatology 31:364-70.
32. Brewer GJ, Kanzer SH, Zimmerman EA, Molho ES, Celmins DF, Heckman SM, Dick R. 2010. Subclinical zinc deficiency in Alzheimer's disease and Parkinson's disease. Am J Alzheimers Dis Other Demen 25(7):572-5.
33. Brocard A, Knol AC, Khammari A, Dreno B. 2007. Hidradenitis suppurativa and zinc: a new therapeutic approach. A pilot study. Dermatol Online J 214(4):325-7.
34. Brooks W. 2004. Zinc for severe pneumonia in very young children: double-blind placebo-controlled trial. Lancet 363:1683-8.
35. Brown KH, Wuehler SE, Peerson JM. 2001. The importance of zinc in human nutrition and estimation of the global prevalence of zinc deficiency. Food Nutr Bull 22:114-8.
36. Bush AI. 2003. The metallobiology of Alzheimer's disease. Trends Neurosci 26(4):207-14.
37. Bush AI, Multhaup G, Moir RD, Williamson TG, Small DH, Rumble B, Pollwein P, Beyreuther K, Masters CL. 1993. A novel zinc (II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease. J Biol Chem 268:16109-12.
38. Campo C, Wellinghausen N, Faber C, Fischer A, Rinkm L. 2001. Zinc inhibits the mixed lymphocyte culture. Biol Trace Elem Res 79:15-22.
39. Cao J, Henry PR, Guo R, Holwerda RA, Toth JP, Littell RC, Miles RD, Ammerman CB. 2000. Chemical characteristics and relative bioavailability of supplemental organic zinc sources for poultry and ruminants. J Anim Sci 78:2039-54.
40. Carlomagno M, Coghlan LG, McMurray DN. 1986. Chronic zinc deficiency and listeriosis in rats: acquired cellular resistance and response to vaccination. Med Microbiol Immunol 175:271-80.
41. Caulfield L, Zavaleta N, Shankar AH, Merialdi M. 1998. Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival. Am J Clin Nutr 68:499S-508S.
42. Caulfield L, Zavaleta N, Figueroa A. 1999a. Adding zinc to prenatal iron and folate supplements improves maternal and neonatal zinc status in a Peruvian population. Am J Clin Nutr 69:1257-63.
43. Caulfield LE, Zavaleta N, Figueroa A, Leon Z. 1999b. Maternal zinc supplementation does not affect size at birth or pregnancy duration in Peru. J Nutr 129:1563-8.
44. Chandra R. 1990. The relation between immunology, nutrition and disease in elderly people. Age Ageing 19:S25-31.
45. Chausmer A. 1998. Zinc, insulin and diabetes. J Am Coll Nutr 17:109-15.
46. Chen MD, Lin PY, Cheng V, Lin WH. 1996. Zinc supplementation aggravates body fat accumulation in genetically obese mice and dietary-obese mice. Biol Trace Elem Res 52(2):125-32.
47. Chen M, Lin PY, Sheu WH. 1997. Zinc status in plasma of obese individuals during glucose administration. Biol Trace Elem Res 60:123-9.
48. Chen MD, Liou SJ, Lin PY, Yang VC, Alexander PS, Lin WH. 1998. Effects of zinc supplementation on the plasma glucose level and insulin activity in genetically obese (ob/ob) mice. Biol Trace Elem Res 61(3):303-11.
49. Chen H, Carlson EC, Pellet L, Moritz JT, Epstein PN. 2001. Overexpression of metallothionein in pancreatic ß-cells reduces streptozotocin-induced DNA damage and diabetes. Diabetes 50:2040-6.
50. Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser W, Kim YS, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, Zheng H, Tanzi RE, Masters CL, Bush AI. 2001. Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 30(3):665-76.
51. Cherry FF, Sandstead HH, Rojas P, Johnson LK, Batson HK, Wang XB. 1989. Adolescent pregnancy: associations among body weight, zinc nutriture, and pregnancy outcome. Am J Clin Nutr 50:945-54.
52. Chimienti F, Devergna S, Favier A, Seve M. 2004. Identification and cloning of a ß-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. Diabetes 53:2330-7.
53. Choi DW, Koh JY. 1998. Zinc and brain injury. Annu Rev Neurosci 21:347-75.
54. Cloues R, Jones S, Brown DA. 1993. Zn2+ potentiates ATP-activated currents in rat sympathetic neurons. Pflugers Arch 424:152-8.
55. Cohen N, Golik A. 2006. Zinc balance and medications commonly used in the management of heart failure. Heart Fail Rev 11:19-24.
56. Contaminants: zinc. [Internet]. Toronto, Canada. E.B.I.: Environmental Bureau of Investigation; 2002. Available from: http://www.e-b-inet/ebi/contaminants/zinc.html. Accessed 2002 March 25.
57. Coombs TL. 1974. The nature of zinc and copper complexes in the oyster Ostrea edulis. Mar Biol 28:1-10.
58. Costello LC, Franklin RB. 2006. The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots. Mol Cancer Res 5:1-13.
59. Cousins RL, Blanchard RK, Popp MP, Liu L, Cao J, Moore JB, Green CL. 2003. A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells. Proc Natl Acad Sci 100:6952-7.
60. Cuajungco MP, Faget KY. 2003. Zinc takes the center stage: its paradoxical role in Alzheimer's disease. Brain Res Rev 41(1):44-56.
61. Cuajungco MP, Lees GJ. 1997a. Zinc and Alzheimer's disease: is there a direct link? Brain Res Rev 23(3):219-36.
62. Cuajungco MP, Lees GJ. 1997b. Zinc metabolism in the brain: relevance to human neurodegenerative disorders. Neurobiol Dis 4(3-4):137-69.
63. Cunningham J, Fu A, Mearkle PL, Brown RG. 1994. Hyperzincuria in individuals with insulin-dependent diabetes mellitus: concurrent zinc status and the effect of high-dose zinc supplementation. Metabolism 43:1158-62.
64. Curtain CC, Ali F, Volitakis I, Cherny RA, Norton RS, Beyreuther K, Barrow CJ, Masters CL, Bush AI, Barnham KJ. 2001. Alzheimer's disease amyloid-β binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. J Biol Chem 276:20466-73.
65. Cutsem JV, Gerven FV, Fransen J, Schrooten P, Janssen PA. 1990. The in vitro antifungal activity of ketoconazole, zinc pyrithione, and selenium sulfide against pityrosporum and their efficacy as a shampoo in the treatment of experimental pityrosporosis in guinea pigs. J Am Acad Dermatol 22(6):993-8.
66. Danielsson J, Pierattelli R, Banci L, Graslund A. 2007. High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid β-peptide. FEBS J 274:46-59.
67. Danscher G, Jensen KB, Frederickson CJ, Kemp K, Andreasen A, Juhl S, Stoltenberg M, Ravid R. 1997. Increased amount of zinc in the hippocampus and amygdala of Alzheimer's diseased brains: a proton-induced x-ray emission spectroscopic analysis of cryostat sections from autopsy material. J Neurosci Methods 76(1):53-59.
68. Darby M. 2005. RNA binding by single zinc fingers. Mol Biol Intelligence Unit 3:66-75.
69. Dawson E, Albers J, McGanity WJ. 1989. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 50:848-52.
70. Desouki MM, Geradts J, Milon B, Franklin RB, Costello LC. 2007. hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands. Mol Cancer Res 6:1-7.
71. Dhalleine C, Assifaoui A, Moulari B, Pellequer B, Cayot P, Lamprecht A, Chambin O. 2011. Zinc-pectinate beads as an in vivo self-assembling system for pulsatile drug delivery. Intl J Pharmaceut 414(1-2):28-34.
72. DiSilvestro R. 2000. Zinc in relation to diabetes and oxidative disease. J Nutr 130:1509S-11S.
73. Donmez N, Donmez HH, Keskin E, Celik I. 2002. Effects of zinc supplementation to ration on some hematological parameters in broiler chicks. Biol Trace Elem Res 87:125-31.
74. Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Colin L, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI. 2010. Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease. Cell 142(6):857-86.
75. Eder K, Kirchgessner M. 1996. Zinc deficiency and the desaturation of linoleic acid in rats force-fed fat-free diets. Biol Trace Elem Res 54:173-83.
76. Elise CC, Deborah RM, Angus GS, Jacob WV, Cathy WL. 2011. Zinc supplementation provides behavioral resiliency in a rat model of traumatic brain injury. Physiol Behav 104(5):942-7.
77. Elsby LM, Roberts SGE. 2008. Interaction of the TFIIB zinc ribbon with RNA polymerase II. Biochem Soc Trans 36:595-8.
78. Erdogan M, Ustuner I, Cengiz B, Soylemez F, Cavdar AO. 2006. Effects of nutrition on zinc, folic acid, and vitamin B12 levels during pregnancy. Biol Trace Elem Res 109:105-13.
79. Fabe J, Grahn BH, Paterson PG. 2000. Zinc concentration of selected ocular tissues in zinc-deficient rats. Biol Trace Elem Res 75:43-52.
80. Fabris N. 1994. Neuroendocrine-immune aging: an integrative view on the role of zinc. Ann NY Acad Sci 719:353-68.
81. Falchuk K. 1998. The molecular basis for the role of zinc in developmental biology. Mol Cell Biochem 188:41-8.
82. Falchuk KH, Montorzi M. 2001. Zinc physiology and biochemistry in oocytes and embryos. Biometals 14:385-95.
83. Favier A. 1992. The role of zinc in reproduction. Hormonal mechanisms. Biol Trace Elem Res 32:363-82.
84. Fiske D, McCoy III HE, Kitchens CR. 1994. Zinc-induced sideroblastic anemia: report of a case, review of the literature, and description of the hematologic syndrome. Am J Hematol 46:147-50.
85. Fong T, Vij R, Vijayan A, DiPersio J, Blinder M. 2007. Copper deficiency: an important consideration in the differential diagnosis of myelodysplastic syndrome. Haematologica 92:1429-30.
86. Franklin RB, Feng P, Milon B, Desouki MM, Singh KK, Kajdacsy-Balla A, Bagasra O, Costello LC. 2005. hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer. Mol Cancer 4:1-13.
87. Fujii A, DiSilvestro R, Frid D, Katz C, Malarkey W. 1997. Short-term zinc supplementation in women with non-insulin-dependent diabetes mellitus: effects on plasma 5'-nucleotidase activities, insulin-like growth factor I concentrations, and lipoprotein oxidation rates in-vitro. Am J Clin Nutr 66:639-42.
88. Fung EB, Ritchie LD, Woodhouse LR, Roehl R, King JC. 1997. Zinc absorption in women during pregnancy and lactation: a longitudinal study. Am J Clin Nutr 66:80-8.
89. Ghasemi A, Zahediasl S, Hosseini-Esfahani F, Syedmoradi L, Azizi F. 2012. Pediatric reference values for serum zinc concentration in Iranian subjects and an assessment of their dietary zinc intakes. Clin Biochem 45:1254-6.
90. Gibson RS, Heath AL, Ferguson EL. 2002. Risk of suboptimal iron and zinc nutriture among adolescent girls in Australia and New Zealand: causes, consequences, and solutions. Asia Pac J Clin Nutr 11:543-52.
91. Gleeson M, Walsh NP, Blannin AK, Robson PJ, Cook L, Donnelly AE, Day SH. 1998. The effect of severe eccentric exercise-induced muscle damage on plasma elastase, glutamine and zinc concentrations. Eur J Appl Physiol Occup Physiol 77:543-6.
92. Golden MHN, Golden BE. 1981. Trace elements potential importance in human nutrition with particular reference to zinc and vanadium. Br Med Bull 37:31-6.
93. Goldenberg RL, Tamura T, Neggers Y, Copper RL, Johnston KE, DuBard MB, Hauth JC. 1995. The effect of zinc supplementation on pregnancy outcome. J Am Med Assoc 274:463-8.
94. Goldfrank LR, Flomenbaum N. 2006.Goldfrank's toxicologic emergencies. 8th ed. New York: McGraw-Hill Professional. p 1981.
95. Golik A, Cohen N, Ramot Y, Maor J, Moses R, Weissgarten J, Leonov Y, Modai D. 1993. Type II diabetes mellitus, congestive heart failure, and zinc metabolism. Biol Trace Elem Res 39:171-5.
96. Grider Jr A, Erway LC. 1986. Intestinal metallothionein in lethal-milk mice with systemic zinc deficiency. Biochem Genet 24:635-42.
97. Grider A, Vazquez F. 1996. Nystatin affects zinc uptake in human fibroblasts. Biol Trace Elem Res 54:97-104.
98. Grider A, Lin YF, Muga SJ. 1998. Differences in the cellular zinc content and 5'-nucleotidase activity of normal and acrodermatitis enteropathica (AE) fibroblasts. Biol Trace Elem Res 61:1-8.
99. Grungreiff K, Reinhold D, Ansorge S. 1999. Serum concentrations of sIL-2R, IL-6, TGF-β1, neopterin, and zinc in chronic hepatitis C patients treated with interferon-alpha. Cytokine 11(12):1076-80.
100. Haase H, Rink L. 2007. Signal transduction in monocytes: the role of zinc ions. BioMetals 20:579-85.
101. Haase H, Rink L. 2009. The immune system and the impact of zinc during aging. Immun Ageing 6(9):1-17.
102. Haase H, Mocchegiani E, Rink L. 2006. Correlation between zinc status and immune function in the elderly. Biogerontology 7:421-8.
103. Hackenberg S, Scherzed A, Harnisch W, Froelich K, Ginzkey C, Koehler C, Hagen R, Kleinsasser N. 2012. Antitumor activity of photo-stimulated zinc oxide nanoparticles combined with paclitaxel or cisplatin in HNSCC cell lines. J Photochem Photobiol B 114:87-93.
104. Haeflein KA, Rasmussen AI. 1977. Zinc content of selected foods. J Am Diet Assoc 70(6):610-6.
105. Hagay Z. 1995. Prevention of diabetes-associated embryopathy by overexpression of the free radical scavenger copper zinc superoxide dismutase in transgenic mouse embryo. Am J Obstet Gynecol 173:1036-41.
106. Haglund B, Ryckenberg K, Selinus O, Dahlquist G. 1996. Evidence of a relationship between childhood-onset type I diabetes and low groundwater concentration of zinc. Diabetes Care 19:873-5.
107. Hamadani JD, Fuchs GJ, Osendarp SJ, Huda SN, Grantham-McGregor SM. 2002. Zinc supplementation during pregnancy and effects on mental development and behavior of infants: a follow-up study. Lancet 360:290-4.
108. Hambidge K, Krebs NF, Sibley L, English J. 1987. Acute effects of iron therapy on zinc status during pregnancy. Obstet Gynecol 70:593-6.
109. Hanas J, Larabee JL, Hocker JR. 2005. Zinc finger interactions with metals and other small molecules. Mol Biol Intelligence Unit 2:39-46.
110. Heinen F, Matern D, Pringsheim W, Leititis JU, Brandis M. 1995. Zinc deficiency in an exclusively breast-fed preterm infant. Eur J Pediatr 154:71-5.
111. Hemila H. 2011. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J 5:51-8.
112. Henkin RI, Smith FR. 1972. Zinc and copper metabolism in acute viral hepatitis. Am J Med Sci 264(5):401-9.
113. Ho E, Quan N, Tsai YH, Lai W, Bray TM. 2001. Dietary zinc supplementation inhibits NFkappaB activation and protects against chemically induced diabetes in CD1 mice. Exp Biol Med 226:103-11.
114. Ho LH, Ruffin RE, Murgia C, Li L, Krilis SA, Zalewski PD. 2004. Labile zinc and zinc transporter ZnT4 in mast cell granules: role in regulation of caspase activation and NF-B translocation1. J Immunol 172:7750-60.
115. Homma S, Murata M, Takenaka M. 1997. Chemical composition and characteristics of zinc(ii)-chelating fraction in instant coffee. 17th International Scientific Colloquium on Coffee - Chemistry, Proceedings of Assn. Scientifique Internationale du Cafe (ASIC) Conferences; Nairobi, Kenya. Dept. of Nutrition and Food Science, Ochanomizu Univ., Ohtsuka, Japan. Available from: www.asic-cafe.org/pdf/abstract/17_012.pdf. Accessed 2012 February 15.
116. Huddlea J, Gibsona RS, Cullinan TR. 1998. Is zinc a limiting nutrient in the diets of rural pregnant Malawian women? Br J Nutr 79:257-65.
117. Huebner K, Druck T, LaForgia S, Lasota J, Croce CM, Lanfrancone L, Donti E, Pengue G, La M G, Pelicci PG. 1993. Chromosomal localization of four human zinc finger cDNAs. Hum Genet 91:217-22.
118. Hunt JR. 2003. Bioavailability of iron, zinc, and other trace minerals from vegetarian diets. Am J Clin Nutr 78:633S-9.
119. Hunt IF, Murphy NJ, Cleaver AE, Faraji B, Swendseid ME, Coulson AH, Clark VA, Laine N, Davis CA, Smith Jr JC. 1983. Zinc supplementation during pregnancy: zinc concentration of serum and hair from low-income women of Mexican descent. Am J Clin Nutr 37:572-82.
120. Hunt IF, Murphy NJ, Cleaver AE, Faraji B, Swendseid ME, Browdy BL, Coulson AH, Clark VA, Settlage RH, Smith Jr JC. 1985. Zinc supplementation during pregnancy in low-income teenagers of mexican descent: effects on selected blood constituents and on progress and outcome of pregnancy. Am J Clin Nutr 42:815-28.
121. Isbir T, Tamer L, Taylor A, Isbir M. 1994. Zinc, copper and magnesium status in insulin-dependent diabetes. Diabetes Res 26:41-5.
122. Jamall I, Ally KM, Yusuf S. 2006. Acrodermatitis enteropathica: zinc therapy and possible identification of a carrier state through multiple hair zinc analyses over three decades. Biol Trace Elem Res 114:93-105.
123. Jameson S. 1993. Zinc status in pregnancy: the effect of zinc therapy on perinatal mortality, prematurity, and placental ablation. Ann NY Acad Sci 678:178-92.
124. Jayasree A, Sasidharan S, Koyakutty M, Nair S, Menon D. 2011. Mannosylated chitosan-zinc sulphide nanocrystals as fluorescent bioprobes for targeted cancer imaging. Carbohydr Polym 85:37-43.
125. Jemec GBE, Revuz J, Leyden JJ, editors. 2006. Hidradenitis suppurativa. Heidelberg, Germany: Springer-Verlag. p 141-2.
126. Jeswani RM, Vani SN. 1991. A study of serum zinc levels in cord blood of neonates and their mothers. Indian J Pedriatr 58:683-6.
127. Jing M, Sun JY, Weng XY. 2007. Insights on zinc regulation of food intake and macronutrient selection. Biol Trace Elem Res 115:187-94.
128. Kadakia S. 1992. Serum and tissue zinc concentrations in patients with endoscopic esophagitis. Dig Dis Sci 37:513-6.
129. Kantola M, Purkunen R, Kroger P, Tooming A, Juravskaja J, Pasanen M, Saarikoski S, Vartiainen T. 2000. Accumulation of cadmium, zinc, and copper in maternal blood and developmental placental tissue: differences between Finland, Estonia, and St. Petersburg. Environ Res 83:54-66.
130. Kasi V, Bodiga S, Kommuguri UN, Sankuru S, Bodiga VL. 2011. Zinc pyrithione salvages reperfusion injury by inhibiting NADPH oxidase activation in cardiomyocytes. Biochem Biophys Res Commun 410(2):270-5.
131. Keeling PW, Jones RB, Hilton PJ, Thompson RP. 1980. Reduced leucocyte zinc in liver disease. Gut 21:561-4.
132. Keeling PW, Ruse W, Bull J, Hannigan B, Thompson RP.1981. Direct measurement of the hepatointestinal extraction of zinc in cirrhosis and hepatitis. Clin Sci 61(4):441-4.
133. Keenan JM, Morris DH. 1993. How to make sure your older patients are getting enough zinc. Geriatrics 48:57-58.
134. Kelleher S, Seo YA, Lopez V. 2009. Mammary gland zinc metabolism: regulation and dysregulation. Genes Nutr 4:83-94.
135. Kienast A, Roth B, Bossier C, Hojabri C, Hoeger PH. 2007. Zinc-deficiency dermatitis in breast-fed infants. Eur J Pediatr 166:189-94.
136. Kilinc M, Coskun A, Bilge F, Imrek SS, Atli Y. 2010. Serum reference levels of selenium, zinc and copper in healthy pregnant women at a prenatal screening program in southeastern mediterranean region of Turkey. J Trace Elem Med Biol 24:152-6.
137. Kimura E, Aoki S, Kikuta E, Koike T. 2003. A macrocyclic zinc (II) fluorophore as a detector of apoptosis. Proc Natl Acad Sci 100:3731-6.
138. King J. 2000. Determinants of maternal zinc status during pregnancy. Am J Clin Nutr 71:1334S-43S.
139. King J. 2001. Effect of reproduction on the bioavailability of calcium, zinc and selenium. J Nutr 131:1355S-8S.
140. Kirksey A, Wachs TD, Yunis F, Srinath U, Rahmanifar A, McCabe GP, Galal OM, Harrison GG, Jerome NW. 1994. Relation of maternal zinc nutriture to pregnancy outcome and infant development in an Egyptian village. Am J Clin Nutr 60:782-92.
141. Klecha AJ, Salgueiro J, Wald M, Boccio J, Zubillaga M, Leonardi NM, Gorelik G, Cremaschi GA. 2005. In vivo iron and zinc deficiency diminished T- and B-selective mitogen stimulation of murine lymphoid cells through protein kinase C-mediated mechanism. Biol Trace Elem Res 104:173-83.
142. Konomi A, Yokoi K. 2005. Zinc deficiency decreases plasma erythropoietin concentration in rats. Biol Trace Elem Res 107:289-92.
143. Krebs N. 2000. Overview of zinc absorption and excretion in the human gastrointestinal tract. J Nutr 130:1374S-7S.
144. Krebs NF, Hambidge KM. 2001. Zinc metabolism and homeostasis: the application of tracer techniques to human zinc physiology. Biometals 14:397-412.
145. Kreft B, Fischer A, Kruger S, Sack K, Kirchner H, Rink L. 2000. The impaired immune response to diphtheria vaccination in elderly chronic hemodialysis patients is related to zinc deficiency. Biogerontology 1:61-6.
146. Krishnan R, Dharmaraj U, Malleshi NG. 2012. Influence of decortication, popping and malting on bioaccessibility of calcium, iron and zinc in finger millet. LWT-Food Sci Technol 48:169-74.
147. Kubisch HM, Wang J, Luche R, Carlson E, Bray TM, Epstein CJ, Phillips JP. 1994. Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes. Proc Natl Acad Sci USA 91:9956-9.
148. Kudo N, Nakagawa Y, Waku K. 1990. Effects of zinc deficiency on the fatty acid composition and metabolism in rats fed a fat-free diet. Biol Trace Elem Res 24(1):49-60.
149. Kues WA, Niemann H. 2011 Advances in farm animal transgenesis. Pre Vet Med 102(2):146-56.
150. Kumar N, Ahlskog JE. 2004. Myelopolyneuropathy due to copper deficiency or zinc excess? Reply. Arch Neurol 61(4):604-5.
151. Kumar P, Rai GP, Flora SJS. 1994. Immunomodulation following zinc supplementation during chelation of lead in male rats. Biometals 7:41-4.
152. Kumar A, Singh BK, Ahmad I, Shukla S, Patel DK, Srivastava G, Kumar V, Pandey HP, Singh C. 2012. Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: similarity with paraquat neurotoxicity. Brain Res 1438:48-64.
153. Kumari M, Khan SS, Pakrashi S, Mukherjee A, Chandrasekaran N. 2011. Cytogenetic and genotoxic effects of zinc oxide nanoparticles on root cells of Allium cepa. J Hazard Mater 190:613-21.
154. Kynast G, Saling E. 1986. Effect of oral zinc application during pregnancy. Gynecol Obstet Invest 21:117-23.
155. Law J, Nelson N, Henkin RI. 1983. Zinc localization in taste bud membranes. Biol Trace Elem Res 5:219-24.
156. Lee JY, Cole TB, Palmiter RD, Suh SW, Koh JY. 2002. Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc Natl Acad Sci 99(11):7705-10.
157. Lew K. 2008. Zinc. 1st ed. New York: The Rosen Publishing Group.
158. Lin AMY. 2001. Coexistence of zinc and iron augmented oxidative injuries in the nigrostriatal dopaminergic system of SD rats. Free Radic Biol Med 30(3):225-31.
159. Lin CC, Huang JF, Tsai LY, Huang YL. 2005. Selenium, iron, copper, and zinc levels and copper-to-zinc ratios in serum of patients at different stages of viral hepatic diseases. Biol Trace Elem Res 109(1):15-23.
160. Lin Y, Wanga X, Wang B, Mohamada O, Wei G. 2012. Bioaccumulation characterization of zinc and cadmium by Streptomyces zinciresistens, a novel actinomycete. Ecotoxicol Environ Safety 77:7-17.
161. Liu ST, Howlett G, Barrow CJ. 1999. Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the aβ peptide of Alzheimer's disease. Biochemistry 38(29):9373-8.
162. Love RA, Parge HE, Wickersham JA, Hostomsky Z, Habuka N, Moomaw EW, Adachi T, Hostomska Z. 1996. The crystal structure of hepatitis c virus ns3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell 87(2):331-42.
163. Lu X, Shen X. 2011. Solubility of bacteria cellulose in zinc chloride aqueous solutions. Carbohydr Polymers 86(1):239-44.
164. Maclean K. 2005. Apoptosis by zinc deficiency. Zinc Finger Proteins 8:265-71.
165. MacPherson S, Akache B, Weber S, Deken XD, Raymond M, Turcotte B. 2005. Candida albicans zinc cluster protein upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes. Antimicrob Agents Chemother 49(5):1745-52.
166. Mahomed K, Williams MA, Woelk GB, Mudzamiri S, Madzime S, King IB, Bankson DD. 2000. Leukocyte selenium, zinc, and copper concentrations in preeclamptic and normotensive pregnant women. Biol Trace Elem Res 75:107-18.
167. Mahomed K, Bhutta Z, Middleton P. 2007. Zinc supplementation for improving pregnancy and infant outcome. Cochrane Database Syst Rev 18.
168. Malhotra A, Fairweather-Taita SJ, Whartona PA, Geea H. 1990. Placental zinc in normal and intra-uterine growth-retarded pregnancies. Br J Nutr 63:613-21.
169. Mankad M, Sathawara NG, Doshi H, Saiyed HN, Kumar S. 2006. Seminal plasma zinc concentration and a-glucosidase activity with respect to semen quality. Biol Trace Elem Res 110:97-106.
170. Mann JJ, Fraker PJ. 2005. Zinc pyrithione induces apoptosis and increases expression of bim. Apoptosis 10:369-79.
171. Marcellini F, Giuli C, Papa R, Gagliardi C, Dedoussis G, Herbein G, Fulop T, Monti D, Rink L, Jajte J, Mocchegiani E. 2006. Zinc status, psychological and nutritional assessment in old people recruited in five european countries: zincage study. Biogerontology 7:339-45.
172. Maret W. 2001. Zinc biochemistry, physiology, and homeostasis: recent insights and current trends. BioMetals 14:187-90.
173. Mariani E, Cattini L, Neri S, Malavolta M, Mocchegiani E, Ravaglia G, Facchini A. 2006. Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status. Biogerontology 7:449-59.
174. Marreiro D, Fisberg M, Cozzolino SMF. 2004. Zinc nutritional status and its relationships with hyperinsulinemia in obese children and adolescents. Biol Trace Elem Res 100:137-49.
175. Matthes N, Mesters JR, Coutard B, Canard B, Snijder EJ, Moll R, Hilgenfeld R. 2006. The non-structural protein Nsp10 of mouse hepatitis virus binds zinc ions and nucleic acids. FEBS Lett 580(17):4143-9.
176. Maverakis E, Fung MA, Lynch PJ, Draznin M, Michael DJ, Ruben B, Fazel N. 2007. Acrodermatitis enteropathica and an overview of zinc metabolism. J Am Acad Dermatol 56:116-24.
177. McClain C, Kasarskis JrEJ, Allen JJ. 1985. Functional consequences of zinc deficiency. Prog Food Nutr Sci 9:185-226.
178. McClain CJ, Shedlofsky S, Barve S, Hill DB. 1997. Cytokines and alcoholicliver disease. Alcohol Health Res W 21:317-20.
179. McQuitty JrJT, DeWys WD, Monaco L, Strain WH, Rob CJ, Apgar J, Pories WJ. 1970. Inhibition of tumor growth by dietary zinc deficiency. Cancer Res 30:1387-90.
180. Meadows NJ, Smith MF, Keeling PWN, Ruse W, Day J, Scopes JW, Thompson RPH, Bloxam DL. 1981. Zinc and small babies. Lancet 318:1135-7.
181. Minami T, Shimane M, Tanaka H, Namikawa K, Ichida S. 2001. Pancreatic exocrine damage induced by subcutaneous injection of a low dosage of zinc. Biol Trace Elem Res 84:169-79.
182. Miranda ER, Dey CS. 2004. Effect of chromium and zinc on insulin signaling in skeletal muscle cells. Biol Trace Elem Res 101:19-36.
183. Mitchell W, Meng I, Nicholson SA, Aspinall R. 2006. Thymic output, ageing and zinc. Biogerontology 7:461-70.
184. Mocchegiani E, Boemi M, Fumelli P, Fabris N. 1989. Zinc-dependent low thymic hormone level in type I diabetes. Diabetes 38:932-7.
185. Mocchegiani E, Bulian D, Santarelli L, Tibaldi A, Muzzioli M, Lesnikov V, Pierpaoli W, Fabris N. 1996. The zinc pool is involved in the immune-reconstituting effect of melatonin in pinealectomized mice. J Pharmacol Exp Ther 277:1200-8.
186. Monnet F, Vaillant N, Hitmi A, Sallanon H. 2004. Photosynthetic activity of Lolium perenne as a function of endophyte status and zinc nutrition. Funct Plant Biol 32:131-9.
187. Morgan SL, Strong DC, Kitchin EM, Johnston KE, Disilvestro RA, Tamura T. 2006. Zinc status of women with low bone mineral density who receives calcium supplements. Biol Trace Elem Res 110:211-22.
188. Muga SJ, Grider A. 1999. Partial characterization of a human zinc deficiency syndrome by differential display. Biol Trace Elem Res 68:1-12.
189. Multhaup G, Bush AI, Pollwein P, Masters CL. 1994. Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP). FEBS Lett 355(2):151-4.
190. Murgia C, Vespignani I, Rami R, Perozzi G. 2006. The Znt4 mutation in lethal milk mice affects intestinal zinc homeostasis through the expression of other zinc transporters. Genes Nutr 1:61-70.
191. Murphy EW, Willis BW, Watt BK. 1975. Provisional tables on the zinc content of foods. J Am Diet Assoc 66(4):345-55.
192. Murr C, Pilz S, Grammer TB, Kleber ME, Bohm BO, Marz W, Fuchs D. 2012. Low serum zinc levels in patients undergoing coronary angiography correlate with immune activation and inflammation. J Trace Elem Med Biol 26:26-30.
193. Nagamine T, Takagi H, Takayama H, Kojima A, Kakizaki S, Mori M, Nakajima K. 2000. Preliminary study of combination therapy with interferon-α and zinc in chronic hepatitis C patients with genotype 1b. Biol Trace Elem Res 75(1-3):53-63.
194. Nakayama A, Fukuda H, Ebara M, Hamasaki H, Nakajima K, Sakurai H. 2002. A new diagnostic method for chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma based on serum metallothionein, copper, and zinc levels. Biol Pharm Bull 25(4):426-31.
195. Neggers YH, Cutter GR, Acton RT, Alvarez JL, Bonner JL, Goldenberg RL, Go RC, Roseman JM. 1990. A positive association between maternal serum zinc concentration and birth weight. Am J Clin Nutr 51:678-84.
196. Noonan CW, Kathman SJ, Sarasua SM, White MC. 2003. Influence of environmental zinc on the association between environmental and biological measures of lead in children. J Expo Sci Environ Epidemiol 13:318-23.
197. Nowak G, Szewczyk B, Pilc A. 2005. Zinc and depression: an update. Pharmacol Rep 57:713-8.
198. O'Brien KO, Zavaleta N, Caulfield LE, Wen J, Abrams SA. 2000. Prenatal iron supplements impair zinc absorption in pregnant Peruvian women. J Nutr 130:2251-5.
199. Ohly P, Dohle C, Abel J, Seissler J, Gleichmann H. 2000. Zinc sulphate induces metallothionein in pancreatic islets of mice and protects against diabetes induced by multiple low doses of streptozotocin. Diabetologia 43:1020-30.
200. Okonofua F, Amolea FA, Emofurietab WO, Ugwua NC. 1989. Zinc and copper concentration in plasma of pregnant women in Nigeria. Intl J Gynecol Obstet 29:19-23.
201. Oliveira ECS, Muller PM, Silva FLM, Nery LTB, De Sa MJC, Guerra MMP, Oliveira-Esquerre KP, Kastelic JP, Douglas RH. 2012. Oral administration of an anti-inflammatory does not compromise the efficacy of intra-testicular injection of zinc gluconate as a contraceptive for dogs. Anim Reprod Sci 132:207-12.
202. Osendarp SJM, van Raaij JMA, Arifeen SE, Wahed MA, Baqui AH, Fuchs GJ. 2000. A randomized, placebo-controlled trial of the effect of zinc supplementation during pregnancy on pregnancy outcome in Bangladeshi urban poor. Am J Clin Nutr 71:114-9.
203. Osendarp SJM, van Raaij JMA, Darmstadt GL, Baqui AH, Hautvast JG, Fuchs GJ. 2001. Zinc supplementation during pregnancy and effects on growth and morbidity in low birth weight infants: a randomized placebo controlled trial. Lancet 357:1080-5.
204. Osis D, Kramer L, Wiatrowski E, Spencer H. 1972. Dietary zinc intake in man. Am J Clin Nutr 25:582-8.
205. Osorio R, Yamauti M, Osorio E, Ruiz-Requena ME, Pashley DH, Tay FR, Toledano M. 2011. Zinc reduces collagen degradation in demineralized human dentin explants. J Dent 39:148-53.
206. Ozden TA, Gokcay G, Issever H, Durmaz O, Sokucu S, Saner G. 2012 Serum and hair zinc levels of infants and their mothers. Clin Biochem 45:753-7.
207. Pang Y, Applegate TJ. 2007. Effects of dietary copper supplementation and copper source on digestive pH, calcium, zinc, and copper complex size in the gastrointestinal tract of the broiler chicken. Poult Sci 86:531-7.
208. Park SY, Birkhold SG, Kubena LF, Nisbet DJ, Ricke SC. 2004. Review on the role of dietary zinc in poultry nutrition, immunity, and reproduction. Biol Trace Elem Res 101:147-63.
209. Pascoal C, Cassio F, Nikolcheva L, Barlocher F. 2010. Realized fungal diversity increases functional stability of leaf litter decomposition under zinc stress. Microb Ecol 59:84-93.
210. Pathak P, Kapil U. 2004. Role of trace elements zinc, copper and magnesium during pregnancy and its outcome. Indian J Pediatr 71:1003-5.
211. Perrone L. 1990. Impaired zinc metabolic status in children affected by idiopathic nephrotic syndrome. Eur J Pediatr 149:438-40.
212. Pfeiffer CC, Braverman ER. 1982. Zinc, the brain and behavior. Biol Psychiatry 17:513-32.
213. Pires L. 2007. The effect of roux-en-y gastric bypass on zinc nutritional status. Obes Surg 17:617-21.
214. Prasad A. 1998. Zinc and immunity. Mol Cell Biochem 188:63-9.
215. Quilliot D, Dousset B, Guerci B, Dubois F, Drouin P, Ziegler O. 2001. Evidence that diabetes mellitus favors impaired metabolism of zinc, copper, and selenium in chronic pancreatitis. Controversies Clin Pancreatol 22:299-306.
216. Rahman MM, Wahed MA, Fuchs GJ, Baqui AH, Alvarez JO. 2002. Synergistic effect of zinc and vitamin A on the biochemical indexes of vitamin A nutrition in children. Am J Clin Nutr 75(1):92-8.
217. Raqib R, Roy SK, Rahman MJ, Azim T, Ameer SS, Chisti J, Andersson J. 2004. Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis. Am J Clin Nutr 79:444-50.
218. Reich H. 1976. Acrodermatitis enteropathica-zinc as a life-saving drug. Hautarzt 27:95-100.
219. Revuz J. 2009. Hidradenitis suppurativa. J Eur Acad Dermatol Venereol 23:985-98.
220. Rink L, Gabriel P. 2001. Extracellular and immunological actions of zinc. BioMetals 14:367-83.
221. Rogalska J, Pilat-Marcinkiewicz B, Brzoska MM. 2011. Protective effect of zinc against cadmium hepatotoxicity depends on this bioelement intake and level of cadmium exposure: a study in a rat model. Chem Biol Interact 193:191-203.
222. Romana DL, Lonnerdal B, Brown KH. 2003. Absorption of zinc from wheat products fortified with iron and either zinc sulfate or zinc oxide. Am J Clin Nutr 78:279-83.
223. Sahin N, Onderci M, Sahin K. 2002. Effects of dietary chromium and zinc on egg production, egg quality, and some blood metabolites of laying hens reared under low ambient temperature. Biol Trace Elem Res 85:47-58.
224. Salehifar E, Shokrzadeh M, Ghaemian A, Aliakbari S, Saravi SS. 2008. The study of Cu and Zn serum levels in idiopathic dilated cardiomyopathy (IDCMP) patients and its comparison with healthy volunteers. Biol Trace Elem Res 125:97-108.
225. Salgueiro MJ, Zubillaga MB, Lysionek AE, Caro RA, Weill R, Boccio JR. 2002. The role of zinc in the growth and development of children. Nutrition 18:510-9.
226. Sandstead HH. 2012. Subclinical zinc deficiency impairs human brain function. J Trace Elem Med Biol 26:70-3.
227. Sandstead HH, Penland JG, Alcock NW, Dayal HH, Chen XC, Li JS, Zhao F, Yang JJ. 1998. Effects of repletion with zinc and other micronutrients on neuropsychologic performance and growth of Chinese children. Am J Clin Nutr 68:470S-5.
228. Savarino L, Granchi D, Ciapetti G, Cenni E, Ravaglia G, Forti P, Maioli F, Mattioli R. 2001. Serum concentrations of zinc and selenium in elderly people: results in healthy nonagenarians/centenarians. Exp Geront 36(2):327-39.
229. Sazawal S, Jalla S, Mazumder S, Sinha A, Black RE, Bhan ME. 1997. Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children. Indian Pediatr 34:589-97.
230. Scholl T, Hediger ML, Schall JI, Fischer RL, Khoo CS. 1993. Low zinc intake during pregnancy: its association with preterm and very preterm delivery. Am J Epidemiol 137:1115-24.
231. Schroeder JJ, Cousins RJ. 1990. Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures. Proc Natl Acad Sci 8(8):3137-41.
232. Seo H, Ogata-Ikeda I, Ishida S, Okano Y, Oyama Y. 2012. A comparison of the cellular actions of polaprezinc (zinc-L-carnosine) and zinc chloride. Life Sci 90:1015-9.
233. Shaha D, Sachdev HPS. 2001. Effect of gestational zinc deficiency on pregnancy outcomes: summary of observation studies and zinc supplementation trials. Br J Nutr 85:S101-8.
234. Shankar AH, Prasad AS.1998. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr 68(2):447S-63.
235. Shisheva A, Gefel D, Shechter Y. 1992. Insulin like effects of zinc ion in vitro and in vivo. Preferential effects on desensitized adipocytes and induction of normoglycemia in streptozotocin-induced rats. Diabetes 41:982-8.
236. Shokrzadeh M, Ghaemian A, Salehifar E, Aliakbari S, Saravi SS, Ebrahimi P. 2009. Serum zinc and copper levels in ischemic cardiomyopathy. Biol Trace Elem Res 127:116-23.
237. Simmer K, Lort-Phillips L, James C, Thompson RP. 1991. A double-blind trial of zinc supplementation in pregnancy. Eur J Clin Nutr 45:139-44.
238. Singh KB, Taneja SK. 2009. Hazard effects of excess of zinc in diet. Sci Vision 9:159-65.
239. Singh RB, Niaz MA, Rastogi SS, Bajaj S, Gaoli Z, Shoumin Z. 1998. Current zinc intake and risk of diabetes and coronary artery disease and factors associated with insulin resistance in rural and urban populations of north India. J Am Coll Nutr 17:564-70.
240. Smith PJ, Wiltshire M, Furon E, Beattie JH, Errington RJ. 2008. Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity. Growth Differentiation Apoptosis 295:C1399-408.
241. Soderberg TA, Sunzel B, Holm S, Elmros T, Hallmans G, Sjoberg S. 1990. Antibacterial effect of zinc oxide in vitro. J Plast Reconstr Surg Hand Surg 24:193-7.
242. Solomon A, Rosenblum G, Gonzales PE, Leonard JD, Mobashery S, Milla ME, Sagi I. 2004. Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-converting enzyme and matrix metalloproteinase despite their high structural similarity. J Biol Chem 279:31646-54.
243. Soltan MH, Jenkins DM. 1982. Maternal and fetal plasma zinc concentration and fetal abnormality. Br J Obstet Gynaecol 89:56-8.
244. Song Y. 2010. Zinc transporter expression profiles in the rat prostate following alterations in dietary zinc. Biometals 23:51-8.
245. Stehbens WE. 2003. Oxidative stress, toxic hepatitis, and antioxidants with particular emphasis on zinc. Exp Mol Pathol 75(3):265-76.
246. Stempniak M, Hostomska Z, Nodes BR, Hostomsky Z. 1997. The NS3 proteinase domain of hepatitis C virus is a zinc-containing enzyme. J Virol 71(4):2881-6.
247. Stray SJ, Ceres P, Zlotnick A. 2004. Zinc ions trigger conformational change and oligomerization of hepatitis b virus capsid protein. Biochemistry 43(31):9989-98.
248. Suck C, Dreno B, Bodin J, inventors; LABCATAL assignee. 2009. Novel use of zinc gluconate for treating hydradenitis suppurativa. United States Patent Application Publication. Pub. No.: US 2009/0215889
249. Takeda A, Tamano H, Ogawa T, Takada S, Ando M, Oku N, Watanabe M. 2012. Significance of serum glucocorticoid and chelatable zinc in depression and cognition in zinc deficiency. Behav Brain Res 226:259-64.
250. Tallman DL, Taylor CG. 2003. Effects of dietary fat and zinc on adiposity, serum leptin and adipose fatty acid composition in C57BL/6J mice. J Nutr Biochem 14(1):17-23.
251. Tamura T, Goldenberg RL, Freeberg LE, Cliver SP, Cutter GR, Hoffman HJ. 1992. Maternal serum folate and zinc concentrations and their relationships to pregnancy outcome. Am J Clin Nutr 56:365-70.
252. Tamura T, Johnston KE, Freeberg LE, Perkins LL, Goldenberg RL. 1994. Refrigeration of blood samples prior to separation is essential for the accurate determination of plasma or serum zinc concentrations. Biol Trace Elem Res 41:165-73.
253. Taylor C. 2005. Zinc, the pancreas, and diabetes: insights from rodent studies and future directions. BioMetals 18:305-12.
254. Tellinghuisen TL, Marcotrigiano J, Rice CM. 2005. Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature 435:374-9.
255. Tobia MH, Zdanowicz MM, Wingertzahn MA, McHeffey-Atkinson B, Slonim AE, Wapnir RA. 1998. The role of dietary zinc in modifying the onset and severity of spontaneous diabetes in the bb wistar rat. Mol Genet Metab 63:205-13.
256. Trombley PQ, Blakemore LJ, Hill BJ. 2011. Zinc modulation of glycine receptors. Neuroscience 186:32-8.
257. Tubek S. 2006a. Differences in selected zinc metabolism parameters in obese and normal-weight hypertensive patients following treatment with spironolactone. Biol Trace Elem Res 114:135-41.
258. Tubek S. 2007a. Zinc ions efflux from lymphocytes in vitro in the presence of a calcium and magnesium ionic environment and its changes following administration of verapamil. Biol Trace Elem Res 117:15-21.
259. Tubek S. 2007b. Correlations between serum zinc concentrations and oxygen balance parameters in patients with primary arterial hypertension. Biol Trace Elem Res 115:213-22.
260. Tubek S. 2007c. Role of zinc in regulation of arterial blood pressure and in the etiopathogenesis of arterial hypertension. Biol Trace Elem Res 117:39-51.
261. Tubek S. 2007d. Selected zinc metabolism parameters in premenopausal and postmenopausal women with moderate and severe primary arterial hypertension. Biol Trace Elem Res 116:249-56.
262. Tubek S. 2007e. Selected zinc metabolism parameters in women with arterial hypotension. Biol Trace Elem Res 116:73-9.
263. Turan B. 2003. Zinc-induced changes in ionic currents of cardiomyocytes. Biol Trace Elem Res 94:49-60.
264. Tuttle S, Aggett PJ, Campbell D, Mac Gillivray I. 1985. Zinc and copper nutrition in human pregnancy: a longitudinal study in normal primigravidae and in primigravidae at risk of delivering a growth retarded baby. Am J Clin Nutr 41:1032-41.
265. Ukkola O, Erkkila PH, Savolainen MJ, Kesaniemi YA. 2001. Lack of association between polymorphisms of catalase, copper-zinc superoxide dismutase (SOD), extracellular SOD and endothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus. J Intern Med 249:451-9.
266. Umeta M, West CE, Fufa H. 2005. Content of zinc, iron, calcium and their absorption inhibitors in foods commonly consumed in Ethiopia. J Food Comp Anal 18(8):803-17.
267. Urrutia R. 2003. KRAB-containing zinc-finger repressor proteins. Genome Biol 4:231.1-231.7.
268. Vaira MD, Bazzicalupi C, Orioli P, Messori L, Bruni B, Zatta P. 2004. Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc (ii) and copper (ii) complexes. Inorg Chem 43(13):3795-7.
269. Van Biervliet S, Van Biervliet JP, Robberecht E. 2006. Serum zinc in patients with cystic fibrosis at diagnosis and after one year of therapy. Biol Trace Elem Res 112:205-11.
270. Van Biervliet S, Van Biervliet JP, Vande Velde S, Robberecht E. 2007. Serum zinc concentrations in cystic fibrosis patients aged above 4 years: a cross-sectional evaluation. Biol Trace Elem Res 119:19-26.
271. Vasto S, Mocchegiani E, Candore G, Listj F, Colonna-Romano G, Lio D, Malavolta M, Giacconi R, Cipriano C, Caruso C. 2006. Inflammation, genes and zinc in ageing and age-related diseases. Biogerontology 7:315-27.
272. Vazquez F, Grider A. 1995. The effect of the acrodermatitis enteropathica mutation on zinc uptake in human fibroblasts. Biol Trace Elem Res 50:109-17.
273. Veena R, Narang AP, Banday AW, Bhan VK. 1991. Copper and zinc levels in maternal and fetal cord blood. Intl J Gynaecol Obstet 35:47-9.
274. Vijayaraghavan K, Pillai SI, Subramanian SP. 2012. Design, synthesis and characterization of zinc-3 hydroxy flavone, a novel zinc metallo complex for the treatment of experimental diabetes in rats. Eur J Pharmacol 680:122-9.
275. Vir S, Love AH, Thompson W. 1981. Zinc concentration in hair and serum of pregnant women in Belfast. Am J Clin Nutr 34:2800-7.
276. Walker FC, Black RE. 2004. Zinc and the risk for infectious disease. Annu Rev Nutr 24:255-75.
277. Walter JrRM, Uriu-Hare JY, Olin KL, Oster MH, Anawalt BD, Critchfield JW, Keen CL. 1991. Copper, zinc, manganese, and magnesium status and complications of diabetes mellitus. Diabetes Care 14:1050-6.
278. Watanabe T, Arakawa T, Fukuda T, Higuchi K, Kobayashi K. 1995. Zinc deficiency delays gastric ulcer healing in rats. Dig Dis Sci 40:1340-4.
279. Wei Z, Burwinkel M, Palissa C, Ephraim E, Schmidt MFG. 2012. Antiviral activity of zinc salts against transmissible gastroenteritis virus in vitro. Vet Microbiol [Serial online]. Article in Press. Available from: http://dx.doi.org/10.1016/j.vetmic.2012.06.019. Accessed 2012 June 19.
280. Weisstaub G, Hertrampf E, Lopez de Romana D, Salazar G, Bugueno C, Castillo-Duran C. 2007. Plasma zinc concentration, body composition and physical activity in obese preschool children. Biol Trace Elem Res 118:167-74.
281. Wellinghausen N, Kirchner H, Rink L. 1997. The significance of zinc for leukocyte biology. Immunol Today 18:519-21.
282. Wojcik J, Dudek D, Schlegel-Zawadzka M, Grabowska M, Marcinek A, Florek E, Piekoszewski W, Nowak RJ, Opoka W, Nowak G. 2006. Antepartum/postpartum depressive symptoms and serum zinc and magnesium levels. Pharmacol Rep 58:571-6.
283. Wu C, Zhang W, Mai K, Xu W, Zhong X. 2011. Effects of dietary zinc on gene expression of antioxidant enzymes and heat shock proteins in hepatopancreas of abalone haliotis discus hannai. Comp Biochem Physiol C 154:1-6.
284. Yasui M, Ota K, Garruto RM. 1993. Concentrations of zinc and iron in the brains of guamanian patients with amyotrophic lateral sclerosis and Parkinsonism-dementia. Neurotoxicology 14(4):445-50.
285. Yucel I, Arpaci F, Ozet A, Doner B, Karayilanoglu T, Sayar A, Berk O. 1994. Serum copper and zinc levels and copper/zinc ratio in patients with breast cancer. Biol Trace Elem Res 40:31-8.
286. Zalewski P. 1994. Video image analysis of labile zinc in viable pancreatic islet cells using a specific fluorescent probe for zinc. J Histochem Cytochem 42:877-84.
287. Zargar AH. 1998. Copper, zinc, and magnesium levels in non-insulin dependent diabetes mellitus. Post Grad Med J 74:665-8.
288. Zavaleta N, Caulfield LE, Garcia T. 2000. Changes in iron status during pregnancy in peruvian women receiving prenatal iron and folic acid supplements with or without zinc. Am J Clin Nutr 71:956-61.
289. Zbinden M, Martinez I, Guyot F, Cambon-Bonavita MA, Gaill F. 2001. Zinc-iron sulphide mineralization in tubes of hydrothermal vent worms. Eur J Mineral 13:653-8.
290. Zhu L, Yan W, Qi M, Hu ZL, Lu TJ, Chen M, Zhou J, Hang CH, Shi JX. 2007. Alterations of pulmonary zinc homeostasis and cytokine production following traumatic brain injury in rats. Ann Clin Lab Sci 37:356-61.
291. Zinc: Human Health Fact Sheet. [Internet] Chicago: Argonne National Laboratory; August 2005. Available from: http://www.ead.anl.gov/pub/doc/zinc.pdf. Accessed 2011 December 6.
292. Zoli A, Altomonte L, Caricchio R, Galossi A, Mirone L, Ruffini MP, Magaro M. 1998. Serum zinc and copper in active rheumatoid arthritis: correlation with interleukin 1ß and tumour necrosis factor alpha. Clin Rheumat 17:378-82.
293. Zuo XL, Chen JM, Zhou X, Li XZ, Mei GY. 2006. Levels of selenium, zinc, copper, and antioxidant enzyme activity in patients with leukemia. Biol Trace Elem Res 114:41-53.