Zinc supplementation provides behavioral resiliency in a rat model of traumatic brain injury

Physiology and Behavior

Volumn 104, Issue 5, 2011, Pages 942-947

  Cope, Elise C ^a   Morris, Deborah R ^a   Scrimgeour, Angus G ^b   VanLandingham, Jacob W ^a   Levenson, Cathy W ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

Author keywords

Anhedonia; Anxiety; Depression; Spatial memory; TBI; Zinc

Indexed keywords

SACCHARIN; ZINC;

ADRENAL GLAND; ANHEDONIA; ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DISEASE SEVERITY; MALE; MAZE TEST; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; SPATIAL MEMORY; SPRAGUE DAWLEY RAT; STRESS; TRAUMATIC BRAIN INJURY; ZINC DEFICIENCY;

ANIMALS; BEHAVIORAL SYMPTOMS; BODY WEIGHT; BRAIN; BRAIN INJURIES; CHOICE BEHAVIOR; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; EATING; MALE; MAZE LEARNING; RATS; RATS, SPRAGUE-DAWLEY; ZINC;

EID: 80053052925     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2011.06.007     Document Type: Article

References (25)

1. Terrio H., Brenner L.A., Ivins B.J., Cho J.M., Helmick K., Schwab K., et al. Traumatic brain injury screening: preliminary findings in a US Army Brigade Combat Team. J Head Trauma Rehabil 2009, 24:14-23.
2. Thurman D.J., Alverson C., Dunn K.A., Guerrero J., Sniezek J.E. Traumatic brain injury in the United States: a public health perspective. J Head Trauma Rehabil 1999, 14:602-615.
3. Jorge R.E., Starkstein S.E. Pathophysiologic aspects of major depression following traumatic brain injury. J Head Trauma Rehabil 2005, 20:475-487.
4. Levin H.S., McCauley S.R., Josic C.P., Boake C., Brown S.A., Goodman H.S., et al. Predicting depression following mild traumatic brain injury. Arch Gen Psychiatry 2005, 62:523-528.
5. Fann J.R., Hart T., Schomer K.G. Treatment for depression after traumatic brain injury: a systematic review. J Neurotrauma 2009, 26:2383-2402.
6. Maes M., D'Haese P.C., Scharpé S., D'Hondt P., Cosyns P., De Broe M.E. Hypozincemia in depression. J Affect Disord 1994, 31:135-140.
7. Maes M., Vandoolaeghe E., Neels H., Demedts P., Wauters A., Melzer H.Y., et al. Lower serum zinc in major depression is a sensitive marker of treatment resistance and of the immune/inflammatory response in that illness. Biol Psychiatry 1997, 42:349-358.
8. Maes M., De Vos N., Demedts P., Wauters A., Neels H. Lower serum zinc in major depression in relation to changes in serum acute phase proteins. J Affect Disord 1999, 56:189-194.
9. Takeda A., Tamano H., Kan F., Itoh H., Oku N. Anxiety-like behavior of young rats after 2-week zinc deprivation. Behav Brain Res 2007, 177:1-6.
10. Tassabehji N.M., Corniola R.S., Alshingiti A., Levenson C.W. Zinc deficiency induces depression-like symptoms in adult rats. Physiol Behav 2008, 95(3):365-369.
11. McClain C.J., Twyman D.L., Ott L.G., Rapp R.P., Tibbs P.A., Norton J.A., et al. Serum and urine zinc response in head-injured patients. J Neurosurg 1986, 64:224-230.
12. Penkowa M., Giralt M., Thomsen P.S., Carrasco J., Hidalgo J. Zinc or copper deficiency-induced impaired inflammatory response to brain trauma may be caused by the concomitant metallothionein changes. J Neurotrauma 2001, 18:447-463.
13. Yeiser E.C., VanLandingham J.W., Levenson C.W. Moderate zinc deficiency increases cell death after brain injury in the rat. Nutr Neurosci 2002, 5:345-352.
14. Young B., Ott L., Kasarskis E., Rapp R., Moles K., Dempsey R.J., et al. Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury. J Neurotrauma 1996, 13:25-34.
15. Cekic M., Cutler S.M., VanLandingham J.W., Stein D.G. Vitamin D deficiency reduces the benefits of progesterone treatment after brain injury in aged rats. Neurobiol Aging 2011, 32:864-874.
16. Rich N.J., VanLandingham J.W., Figueiroa S., Seth R., Corniola R.S., Levenson C.W. Chronic caloric restriction reduces tissue damage and improves spatial memory in a rat model of traumatic brain injury. J Neurosci Res 2010, 88:2933-2939.
17. Salters V.J.M., Sachi-Kocher Afi An ancient metasomatic source for the Walvis Ridge basalts. Chemical Geology 2010, 273:151-167.
18. Suh S.W., Chen J.W., Motamedi M., Bell B., Listiak K., Pons N.F., et al. Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury. Brain Res 2000, 852:268-273.
19. Hellmich H.L., Frederickson C.J., DeWitt D.S., Saban R., Parsley M.O., Stephenson R., et al. Protective effects of zinc chelation in traumatic brain injury correlate with upregulation of neuroprotective genes in rat brain. Neurosci Lett 2004, 355:221-225.
20. Hellmich H.L., Eidson K., Cowart J., Crookshanks J., Boone D.K., Shah S., et al. Chelation of neurotoxic zinc levels does not improve neurobehavioral outcome after traumatic brain injury. Neurosci Lett 2008, 440:155-159.
21. Cope E.C., Levenson C.W. Role of zinc in the development and treatment of mood disorders. Curr Opin Clin Nutr Metab Care 2010, 13:685-689.
22. IOM Mineral requirements for military personnel: Levels needed for cognitive and physical performance during garrison training 2006, The National Academies Press, Washington, DC.
23. Siwek M., Dudek D., Paul I.A., Sowa-Ku-ma M., Popik P., et al. Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. J Affect Disord 2009, 118:187-195.
24. Tahmasebi Boroujeni S., Naghdi N., Shahbazi M., Farrokhi A., Bagherzadeh F., Kazemnejad A., et al. The effect of severe zinc deficiency and zinc supplement on spatial learning and memory. Biol Trace Elem Res 2009, 130:48-61.
25. Chu Y., Mouat M.F., Harris R.B., Coffield J.A., Grider A. Water maze performance and changes in serum corticosterone levels in zinc-deprived and pair-fed rats. Physiol Behav 2003, 78:569-578.