Effects of repletion with zinc and other micronutrients on neuropsychologic performance and growth of Chinese children

American Journal of Clinical Nutrition

Volumn 68, Issue 2 SUPPL., 1998, Pages

  Sandstead, Harold H ^a   Penland, James G ^b   Alcock, Nancy W ^b   Dayal, Hari H ^b   Chen, Xue C ^b   Li, Jui S ^b   Zhao, Faji ^b   Yang, Jia J ^b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b NONE

Author keywords

Brain; Children; China; Cognition; Computerized testing of brain function; Growth; Knee height; Micronutrients; Neuromotor function; Neuropsychologic performance; Zinc

Indexed keywords

TRACE ELEMENT; ZINC;

ANEMIA; BRAIN FUNCTION; CHILD; CHILD GROWTH; CHINA; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE CONTROL; DOUBLE BLIND PROCEDURE; FERRITIN BLOOD LEVEL; GROWTH CURVE; GROWTH RETARDATION; HUMAN; MAJOR CLINICAL STUDY; NEUROMUSCULAR FUNCTION; NEUROPSYCHOLOGICAL TEST; PRACTICE GUIDELINE; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; ZINC BLOOD LEVEL; ZINC DEFICIENCY;

EID: 0031880950     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/68.2.470S     Document Type: Conference Paper

References (67)

1. Todd WR, Elvehjem CA, Hart EB. Zinc in the nutrition of the rat. Am J Physiol 1934;107:146-56.
2. Eggleton W. The zinc and copper contents of the organs and tissues of Chinese subjects. Biochem J 1940;34:991-7.
3. Eggleton W. The zinc and copper content of blood in beriberi, in conditions associated with protein deficiency and in diabetes mellitus. Chin J Physiol 1940;15:33.
4. Prasad AS, Halsted JA, Nadimi M. Syndrome of iron deficiency anemia, hepatosplenomegaly, hypogonadism, dwarfism and geophagia. Am J Med 1961;31:532-46.
5. Halsted J, Ronaghy H, Abadi P, et al. Zinc deficiency in man: the Shiraz experiment. Am J Med 1972;53:277-84.
6. Ronaghy HA, Reinhold JG, Mahloudji M, Ghavami P, Fox MR, Halsted JA. Zinc supplementation of malnourished schoolboys in Iran: increased growth and other effects. Am J Clin Nutr 1974; 27:112-21.
7. Ronaghy HA, Halsted JA. Zinc deficiency occurring in females. Report of two cases. Am J Clin Nutr 1975;28:831-6.
8. Prasad A, Miale A Jr, Farid Z, Sandstead H, Schulert A. Zinc metabolism in patients with syndrome of iron deficiency anemia, hepatosplenomegaly, dwarfism and hypogonadism. J Lab Clin Med 1963;61:537-49.
9. Prasad AS, Miale A Jr, Farid Z, Sandstead HH, Schulert AR, Darby WJ. Biochemical studies on dwarfism, hypogonadism and anemia. Arch Intern Med 1963;111:407-28.
10. Sandstead HH, Prasad AS, Schulert AR, et al. Human zinc deficiency, endocrine manifestations and response to treatment. Am J Clin Nutr 1967;20:422-42.
11. Gibson R. Zinc nutrition in developing countries. Nutr Res Rev 1994;7:151-73.
12. Sandstead HH. Is zinc deficiency a public health problem? Nutrition 1995;11:87-92.
13. Chen XC, Yin TA, He JS. Low levels of zinc in hair and blood, pica, anorexia, and poor growth in Chinese preschool children. Am J Clin Nutr 1985;42:694-700.
14. Halas ES, Eberhardt MJ. A behavioral review of trace element deficiencies in animals and humans. Nutr Behav 1987;3:257-71.
15. Strobel DA, Sandstead HH. Social and learning changes following prenatal or postnatal zinc deprivation in Rhesus monkeys. In: Frederickson C, Howell G, Kasarkis E, eds. The neurobiology of zinc, part B: deficiency, toxicity and pathology. New York: Alan R Liss, 1984:121-38.
16. Golub MS, Takeuchi PT, Keen CL, Gershwin ME, Hendrickx AG, Lönnerdal B. Modulation of behavioral performance of prepubertal monkeys by moderate dietary zinc deprivation. Am J Clin Nutr 1994;60:238-43.
17. Golub M, Keen C, Gershwin M, Hendrickx A. Developmental zinc deficiency and behavior. J Nutr 1995;125:2263S-71S (suppl).
18. Tucker DM, Sandstead HH. Neuropsychological function in experimental zinc deficiency in humans. In: Frederickson CJ, Howell GA, Kasarkis EF, eds. The neurobiology of zinc. New York: Alan R Liss, 1984:139-52.
19. Penland JG. Cognitive performance effects of low zinc (Zn) intakes in healthy adult men. FASEB J 1991;5:A938 (abstr).
20. Darnell LS, Sandstead HH. Iron, zinc and cognition of women. Am J Clin Nutr 1991;53(3):P-16 (abstr).
21. Sandstead H, Alcock N, Dayal H, et al. Effects of zinc (Zn) and micronutrient (M) repletion on Chinese children. In: Fischer P, L'Abbé K, Cockell K, Gibson R, eds. Trace elements in man and animals - 9. Ottawa: National Research Council Research Press, 1997:506-8.
22. Penland J, Sandstead H, Alcock N, et al. Preliminary report: effects of zinc and micronutrient repletion on growth and neuropsychological function of urban Chinese children. J Am Coll Nutr 1997; 16:268-72.
23. Sandstead H, Penland J, Alcock N. Essentiality of zinc In human nutrition. In: Langley A, Mangus S, eds. Zinc, report of an international meeting. Mount Lofty House, Adelaide, South Australia. Rundle Mall, Australia: Public and Environmental Health Services. South Australian Health Commission, 1997:1-9.
24. Sandstead HH, Darnell LS, Wallwork JC. Role of zinc and the contribution of meat to human nutrition. In: Pearson A, Dutson T, eds. Meat and health. New York: Elsevier Applied Science, 1990: 237-74.
25. Sandström B, Almgren A, Kivisto B, Cederblad A. Zinc absorption in humans from meals based on rye, barley, oatmeal, triticale, and whole wheat. J Nutr 1987;117:1898-902.
26. Sandström B, Sandberg A. Inhibitory effects of isolated inositol phosphates on zinc absorption. J Trace Elem Electrolytes Health Dis 1992;6:99-103.
27. Knudsen E, Sandström B, Solgaard P. Zinc, copper and magnesium absorption from a fiber-rich diet. J Trace Elem Med Biol 1996;10:68-76.
28. Sandstead H, Vo-Khactu K, Solomons NI. Conditioned zinc deficiencies. In: Prasad A, ed. Trace elements in human health and disease. New York: Academic Press, 1976:33-49.
29. McNall A, Etherton T, Fosmire G. The impaired growth induced by zinc deficiency in rats is associated with decreased expression of the hepatic insulin-like growth factor I and growth hormone receptor genes. J Nutr 1995;125:874-9.
30. Terhune MW, Sandstead HH. Decreased RNA polymerase activity in mammalian zinc deficiency. Science 1972;177:68-9.
31. Duncan J, Hurley L. Thymidine kinase and DNA polymerase activity in normal and zinc deficient developing rat embryos. Proc Soc Exp Biol Med 1978;159:39-43.
32. Hicks S, Wallwork J. Effect of dietary zinc deficiency on protein synthesis in cell free systems isolated from rat liver. J Nutr 1987;117:1234-40.
33. Dvergsten CL, Fosmire GJ, Ollerich DA, Sandstead HH. Alterations in the postnatal development of the cerebellar cortex due to zinc deficiency, impaired acquisition of granule cells. Brain Res 1983;271:217-26.
34. Dvergsten C, Fosmire G, Ollerich D, Sandstead H. Alterations in the postnatal development of the cerebellar cortex due to zinc deficiency. II. Impaired maturation of Purkinje cells. Brain Res 1984;318:11-20.
35. Sandstead HH. Zinc: essentiality for brain development and function. Nutr Rev 1985;43:129-37.
36. Hesse G. Chronic zinc deficiency alters neuronal function of hippocampal mossy fibers. Science 1979;205:1005-7.
37. Frederickson C, Danscher G. Zinc-containing neurons in hippocamus and related CNS structures. Prog Brain Res 1990;83:71-84.
38. Masters B, Quaife C, Erickson J, et al. Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles. J Neurosci 1994;14:5844-57.
39. Churchich J, Scholz G, Kwok F. Activation of pyridoxal kinase by metallothionein. Biochim Biophys Acta 1989;996:181-6.
40. Yamada Y, Merrill A, McCormick D. Probable reaction mechanisms of flavokinase and FAD synthetase from rat liver. Arch Biochem Biophys 1990;278:125-30.
41. Dakshinamurti K, Paulose C, Viswanathan M, Siow Y, Sharma S. Neurobiology of pyridoxine. Ann N Y Acad Sci 1990;585:128-44.
42. Decker K. Biosynthesis of enzymes with covalently bound flavin. In: Olson R, Bier D, McCormick D, eds. Annual review of nutrition. Vol. 13. Palo Alto, CA: Annual Reviews Inc, 1993:17-41.
43. Li M, Rosenberg H, Chiu T. Zinc inhibition of GABA-stimulated Cl-influx in rat brain regions is unaffected by acute or chronic benzodiazepine. Pharmacol Biochem Behav 1994;49:477-82.
44. Tejwani G, Hanissian S. Modulation of mu, delta and kappa opioid receptors in rat brain by metal ions and histidine. Neuropharmacology 1990;29:445-52.
45. Browning J, O'Dell B. Low zinc status in guinea pigs impairs calcium uptake by brain synaptosomes. J Nutr 1994;124:436-43.
46. Browning J, O'Dell B, Zinc deficiency decreases the concentration of N-methyl-D-aspartate receptors in guinea pig cortical synaptic membranes. J Nutr 1995;125:2083-9.
47. Johnson P, Hunt CD, Milne DB, Mullen LK. Homeostatic control of zinc metabolism in men: zinc excretion and balance in men fed diets low in zinc. Am J Clin Nutr 1993;57:557-65.
48. Carter J, Grivetti L, Davis J, et al. Growth and sexual development of adolescent Egyptian village boys. Effects of zinc, iron, and placebo supplements. Am J Clin Nutr 1969;22:59-78.
49. National Research Council. Recommended dietary allowances. 10th ed. Washington, DC: National Academy Press, 1989.
50. Mills C. Dietary interactions involving trace elements. In: Olson R, Beutler E, Broquist H, eds. Annual review of nutrition. Palo Alto, CA: Annual Reviews Inc, 1985:173-93.
51. Milne DB, Canfield WK, Mahalko JR, Sandstead HH. Effect of oral folic acid supplements on zinc, copper, and iron absorption and excretion. Am J Clin Nutr 1984;39:535-9.
52. Simmer K, Iles CA, Thompson RP. Are iron-folate supplements harmful? Am J Clin Nutr 1987;45:122-5.
53. Fisher S, Alcock N, Amirian J, Altshuler H. Neonatal and maternal hair zinc levels in a nonhuman primate model of the fetal alcohol syndrome. Alcoholism: clinical and research 1988;12:417-21.
54. Polson R, Kenna J, Shears I, Bomford A, Williams R. Measurement of ferritin in serum by an indirect competitive enzyme-linked immunosorbant assay. Clin Chem 1988;34:661-4.
55. Halsted W. Brain and intelligence. Chicago: University of Chicago Press, 1974.
56. Ammons RB. Acquisition of motor skill. Quantitative analysis and theoretical formulation. Psychol Rev 1947;54:263-81.
57. Rosvold HE, Mirsky AF, Sarason I, Brandsome ED, Beck LH. A continuous performance test of brain damage. J Consult Psychol 1956;20:343-50.
58. Benton A. Revised visual retention test. 4th ed. New York: Psychological Corporation, 1974.
59. Wepman J, Turaids D. Spatial orientation memory test manual of directions. Palm Springs, CA: Language Research Association, 1975.
60. Pollitt E, Viteri F, Saco-Pollitt C, Leibel R. Behavioral effects of iron deficiency anemia in children. In: Pollitt E, Leibel R, eds. Iron deficiency: brain biochemistry and behavior. New York: Raven Press, 1982.
61. Cronk C, Stallings V, Spender Q, Ross J, Widdoes H. Measurement of short-term growth with a new knee height measuring device. Am J Human Biol 1989;1:421-8.
62. Pilch S, Senti F. Assessment of zinc nutritional status of the U.S. population based on data collected in the second National Health & Nutrition Examination Survey 1976-1980. Bethesda, MD: Life Sciences Research Office, FASEB, 1984.
63. Penland J, Sandstead H, Alcock N, et al. Cognitive and psychomotor effects of zinc and micronutrient supplementation of urban Chinese children. J Nutr (in press).
64. Bertazzo A, Costa C, Biasiolo M, Allegri G, Cirrincione G, Presti G. Determination of copper and zinc levels in human hair. Influence of sex, age, and pigmentation. Biol Trace Elem Res 1996;52:37-53.
65. Pekarek R, Sandstead HH, Jacob R, Barcome D. Abnormal cellular immune responses during acquired zinc deficiency. Am J Clin Nutr 1979;32:1466-71.
66. Gibson R, Smit-Vanderkooy P, MacDonald A, Goldman A, Ryan B, Berry M. A growth-limiting, mild zinc-deficiency syndrome in some Southern Ontario boys with low height percentiles. Am J Clin Nutr 1989;49:1266-73.
67. Cavan K, Gibson RS, Grazioso CF, Isalgue AM, Ruz M, Solomans NW. Growth and body composition of periurban Guatemalan children in relation to zinc status: a longitudinal zinc intervention trial. Am J Clin Nutr 1993;57:344-52.