Zinc supplementation aggravates body fat accumulation in genetically obese mice and dietary-obese mice

Biological Trace Element Research

Volumn 52, Issue 2, 1996, Pages 125-132

  Chen, Ming Der ^a   Lin, Pi Yao ^b   Cheng, Vie ^b   Lin, Wen Han ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b TUNGHAI UNIVERSITY   (Taiwan)

Author keywords

Body fat; dietary obese mice; ob ob mice; zinc

Indexed keywords

ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FAT; CARCASS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; GENETIC PREDISPOSITION; MOUSE; NONHUMAN; OBESITY; TEST MEAL; ZINC DEFICIENCY; ZINC METABOLISM;

ANIMALIA;

EID: 0029952708     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02789454     Document Type: Article

References (23)

1. B. L. Vallee and K. H. Falchuk, The biochemical basis of zinc physiology, Physiol. Rev. 73, 79-118 (1993).
2. P. J. Collipp, New development in medical therapy of obesity: thyroid and zinc, Pediatr. Ann. 13, 465-472 (1984).
3. M. D. Chen, P. Y. Lin, W. H. Lin, and V. Cheng, Zinc in hair and serum of obese individuals in Taiwan, Am. J. Clin. Nutr. 48, 1307-1309 (1988).
4. G. Di-Martino, M. G. Matera, B. De-Martino, C. Vacca, S. Di-Martino, and F. Rossi, Relationship between zinc and obesity, J. Med. 24, 177-183 (1993).
5. M. L. Kennedy and M. L. Failla, Zinc metabolism in genetically obese (ob/ob) mice, J. Nutr. 117, 886-893 (1987).
6. N. Begin-Heick, M. Daple-Scott, J. Rowe, and M. M. Heick, Zinc supplementation attenuates insulin secretory activity in pancreatic islets of the ob/ob mouse, Diabetes 34, 179-184 (1985).
7. W. H. Lin, M. D. Chen, and P. Y. Lin, Investigation of the profile of selected trace metals in genetically obese (ob/ob) and lean (+/?) mice, J. Formosan. Med. Assoc. 91, s27-s33 (1992).
8. M. D. Chen, W. H. Lin, and P. Y. Lin, Zinc sulfate and thyroxine treatment on the obese patients, Chin. Med. J. 48, 210-216 (1991).
9. H. P. Roth and M. Kirchgessner, Zinc and insulin metabolism, Biol Trace Element Res. 3, 13-32 (1981).
10. A. Shisheva, D. Gefel, and Y. Shechter, Insulinlike effects of zinc ion in vitro and in vivo: preferential effects on desensitized adipocytes and induction of normoglycemia in streptozocin-induced rats, Diabetes 41, 982-988 (1992).
11. P. Faure, A. Roussel, C. Coudray, M. J. Richard, S. Halimi, and A. Favier, Zinc and insulin sensitivity, Biol. Trace Element Res. 32, 305-310 (1992).
12. B. D. Gehm, W. L. Kuo, R. K. Perlman, and M. R. Rosner, Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding, J. Biol. Chem. 268, 7943-7948 (1993).
13. S. Kobayshi, Y. Gao, R. L. Ong, and C. S. Pittman, Substrate specificity of iodothyronine 5′-deiodinase in rat liver homogenates and its requirements of divalent cations in vitro, Life Sci. 16, 2231-2238 (1986).
14. M. I. Surks, I. J. Ramirez, L. E. Shapiro, and M. Kumara-Siri, Effect of zinc (II) and other divalent cations on binding of 3,5,3′-triiodo-1-thyronine to nuclear receptors from cultured GC cells, J. Biol. Chem. 264, 9820-9826 (1989).
15. A. Goel, D. Dhawan, and S. Kheruka, Evaluation of zinc in the regulation of serum T3 and T4 levels and hepatic functions in carbontetrachloride-intoxicated rats, Biol. Trace Element Res. 41, 59-68 (1994).
16. P. Y. Lin, D. R. Romsos, and G. A. Leveille, Food intake, body weight gain, and body composition of the young obese (ob/ob) mouse, J. Nutr. 107, 1715-1723 (1977).
17. W. H. Lin, P. Y. Lin, M. D. Chen, V. Cheng, C. T. Tsou, Y. S. Wang, and E. Lin, Effects of zinc and thyroxine treatment on dietary-obese mice, Proc. Natl. Sci. Counc. ROC. B. 11, 341-346 (1987).
18. K. H. Falchuk, K. L. Hilt, and B. L. Vallee, Determination of zinc in biological samples by atomic absorption spectrometry, Methods Enzymol. 158, 422-434 (1988).
19. R. G. D. Steel and J. H. Torrie, Principles and Procedures of Statistics, 2nd ed., McGraw-Hill, New York (1980).
20. A. D. Mooradian and J. E. Morley, Micronutrient status in diabetes mellitus, Am. J. Clin. Nutr. 45, 877-895 (1987).
21. M. D. Chen, P. Y. Lin, C. T. Tsou, J. J. Wang, and W. H. Lin, Selected metals status in patients with non-insulin dependent diabetes mellitus, Biol. Trace Element Res. 50, 119-124 (1995).
22. C. J. Bailey and P. R. Flatt, Islet defects and insulin resistance in models of obese non-insulin-dependent diabetes, Diabetes Metabolism Rev. 9, 43s-50s (1993).
23. J. E. Silva, Hormonal control of thermogenesis and energy dissipation, Trends Endocrinol. Metab. 4, 25-32 (1993).