Zinc pyrithione salvages reperfusion injury by inhibiting NADPH oxidase activation in cardiomyocytes

Biochemical and Biophysical Research Communications

Volumn 410, Issue 2, 2011, Pages 270-275

  Kasi, Viswanath ^a   Bodiga, Sreedhar ^b   Kommuguri, Upendra Nadh ^c   Sankuru, Suneetha ^c   Bodiga, Vijaya Lakshmi ^c  

^a ANDHRA UNIVERSITY   (India)

^b UNIVERSITY OF ALBERTA   (Canada)

^c KRISHNA UNIVERSITY   (India)

Author keywords

NADPH oxidase; P47phox; Reperfusion injury; Zinc

Indexed keywords

LACTATE DEHYDROGENASE; PROTEIN P47; PYRITHIONE ZINC; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MUSCLE CELL; HYPOXIA; ISCHEMIA; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REOXYGENATION; REPERFUSION INJURY;

ANIMALS; CELLS, CULTURED; CYTOPROTECTION; MEMBRANE GLYCOPROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NADPH OXIDASE; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; PHOSPHORYLATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 79959700905     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.05.130     Document Type: Article

References (34)

1. Piper H.M., Meuter K., Schafer C. Cellular mechanisms of ischemia-reperfusion injury. Ann. Thorac. Surg. 2003, 75:S644-S648.
2. Yellon D.M., Hausenloy D.J. Myocardial reperfusion injury. New Engl. J. Med. 2007, 357:1121-1135.
3. Poltronieri R., Cevese A., Sbarbati A. Protective effect of selenium in cardiac ischemia and reperfusion. Cardioscience 1992, 3:155-160.
4. Gross G.J., Farber N.E., Hardman H.F., Warltier D.C. Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs. Am. J. Physiol. 1986, 250:372-377.
5. Opie L.H. Reperfusion injury and its pharmacologic modification. Circulation 1989, 80:1049-1062.
6. Kloner R.A., Przyklenk K., Whittaker P. Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues. Circulation 1989, 80:1115-1127.
7. Kilgore K.S., Lucchesi B.R. Reperfusion injury after myocardial infarction: the role of free radicals and the inflammatory response. Clin. Biochem. 1993, 26:359-370.
8. Godin D.V., Garnett M.E. Altered antioxidant status in the ischemic/reperfused rabbit myocardium: effects of allopurinol. Can. J. Cardiol. 1989, 5:365-371.
9. Pyles L.A., Fortney J.E., Kudlak J.J., Gustafson R.A., Einzig S. Plasma antioxidant depletion after cardiopulmonary bypass in operations for congenital heart disease. J. Thorac. Cardiovasc. Surg. 1995, 110:165-171.
10. Ko K.M., Garnett M.E., Godin D.V. Altered antioxidant status in ischemic/reperfused rabbit myocardium: reperfusion time-course study. Can. J. Cardiol. 1990, 6:299-304.
11. Leichtweis S., Ji L.L. Glutathione deficiency intensifies ischaemia-reperfusion induced cardiac dysfunction and oxidative stress. Acta Physiol. Scand. 2001, 172:1-10.
12. Akki A., Zhang M., Murdoch C., Brewer A., Shah A.M. NADPH oxidase signaling and cardiac myocyte function. J. Mol. Cell. Cardiol. 2009, 47:15-22.
13. Fukui T., Yoshiyama M., Hanatani A., Omura T., Yoshikawa J., Abe Y. Expression of p22phox and gp91phox, essential components of NADPH oxidase, increases after myocardial infarction. Biochem. Biophys. Res. Commun. 2001, 281:1200-1206.
14. Cai H., Griendling K.K., Harrison D.G. The vascular NADPH oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol. Sci. 2003, 24:471-478.
15. Karagulova G., Yue Y., Moreyra A., Boutjdir M., Korichneva I. Protective role of intracellular zinc in myocardial ischemia/reperfusion is associated with preservation of protein kinase C isoforms. J. Pharmacol. Exp. Ther. 2007, 321:517-525.
16. Chanoit G., Lee S., Xi J., Zhu M., McIntosh R.A., Mueller R.A., Norfleet E.A., Xu Z. Exogenous zinc protects cardiac cells from reperfusion injury by targeting mitochondrial permeability transition pore through inactivation of glycogen synthase kinase-3. Am. J. Physiol. Heart Circ. Physiol. 2008, 295:H1227-1233.
17. Lee S., Chanoit G., McIntosh R.A., Zvara D.A., Xu Z. Molecular mechanism underlying Akt activation in zinc-induced cardioprotection. Am. J. Physiol. Heart Circ. Physiol. 2009, 297:H569-H575.
18. Viswanath K., Bodiga S., Balogun V., Zhang A., Bodiga V.L. Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation. Biometals 2011, 24:171-180.
19. Rey F.E., Cifuentes M.E., Kiarash A., Quinn M.T., Pagano P.J. Novel competitive inhibitor of NADPH oxidase assembly attenuates vascular superoxide and systolic blood pressure in mice. Circ. Res. 2001, 89:408-414.
20. Bodiga S., Zhang R., Jacobs D.E., Larsen B.T., Tampo A., Manthati V.L., Kwok W.M., Zeldin D.C., Falck J.R., Gutterman D.D., Jacobs E.R., Medhora M. Protective actions of Epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channels. J. Mol. Cell. Cardiol. 2009, 46:978-988.
21. S. Bodiga, J.C. Zhong, W. Wang, R. Basu, J. Lo, G.C. Liu, D. Guo, S.M. Holland, J.W. Scholey, J.M. Penninger, Z. Kassiri, G.Y. Oudit, Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by the loss of p47phox NADPH oxidase subunit, Cardiovasc. Res. (2011) (Epubaheadofprint.PMID21285291).
22. Heymes C., Bendall J.K., Ratajczak P., Cave A.C., Samuel J.L., Hasenfuss G., Shah A.M. Increased myocardial NADPH oxidase activity in human heart failure. J. Am. Coll. Cardiol. 2003, 41:2164-2171.
23. Looi Y.H., Greive D.J., Siva A., Walker S.J., Anilkumar N., Cave A.C., Marber M., Monaghan M.J., Shah A.M. Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction. Hypertension 2008, 51:319-325.
24. Qin F., Simeone M., Patel R. Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction. Free Radic. Biol. Med. 2007, 43:271-281.
25. Kim Y.M., Kattach H., Ratnatunga C., Pillai R., Channon K.M., Casadei B. Association of atrial nicotinamide adenine dinucleotide phosphate oxidase activity with the development of atrial fibrillation after cardiac surgery. J. Am. Coll. Cardiol. 2008, 51:68-74.
26. Borchi E., Parri M., Papucci L., Becatti M., Nassi N., Nassi P., Nediani C. Role of NADPH oxidase in H9c2 cardiac muscle cells exposed to simulated ischaemia-reperfusion. J. Cell. Mol. Med. 2009, 13:2724-2735.
27. Hoffmeyer M.R., Jones S.P., Ross C.R., Sharp B., Grisham M.B., Laroux F.S., Stalker T.J., Scalia R., Lefer D.J. Myocardial ischemia/reperfusion injury in NADPH-oxidase deficient mice. Circ. Res. 2000, 87:812-817.
28. Frantz S., Brandse R.P., Hu K., Ramelt K., Wolf J., Scheuermann H., Ertl G., Bauersachs J. Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91PHOX. Basic Res. Cardiol. 2006, 101:127-132.
29. Tao L., Gao E., Jiao X., Yuan Y., Li S., Christopher T.A., Lopez B.L., Koch W., Chan L., Goldstein B.J., Ma X.L. Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress. Circulation 2007, 115:1408-1416.
30. Piper H.M., Garcia-Dorado D., Ovize M. A fresh look at reperfusion injury. Cardiovasc. Res. 1998, 38:291-300.
31. Nayler W.G. The role of calcium in the ischemic myocardium. Am. J. Pathol. 1981, 102:262-270.
32. Anversa P., Cheng W., Liu Y., Leri A., Redaelli G., Kajstura J. Apoptosis and myocardial infarction. Basic Res. Cardiol. 1998, 93:8-12.
33. Jennings R.B., Reimer K.A. Lethal myocardial ischemic injury. Am. J. Pathol. 1981, 102:241-255.
34. Vanden Hoek T.L., Shao Z., Li C., Zak R., Schumacker P.T., Becker L.B. Reperfusion injury in cardiac myocyte after simulated ischemia. Am. J. Physiol. Heart Circ. Physiol. 1996, 270:H1334-H1341.