-
1
-
-
79957627493
-
2020 vision for vaccines against HIV tuberculosis and malaria
-
Rappuoli R, Aderem A. 2020 vision for vaccines against HIV, tuberculosis and malaria. Nature 2011;473(7348):463-9
-
(2011)
Nature
, vol.473
, Issue.7348
, pp. 463-469
-
-
Rappuoli, R.1
Aderem, A.2
-
2
-
-
36849091434
-
Bridging the knowledge gaps in vaccine design
-
Rappuoli R. Bridging the knowledge gaps in vaccine design. Nat Biotechnol 2007;25(12): 1361-6
-
(2007)
Nat Biotechnol
, vol.25
, Issue.12
, pp. 1361-1366
-
-
Rappuoli, R.1
-
3
-
-
33750862932
-
Vaccine manufacturing: Challenges and solutions
-
Ulmer JB, Valley U, Rappuoli R. Vaccine manufacturing: Challenges and solutions. Nat Biotechnol 2006;24(11):1377-83
-
(2006)
Nat Biotechnol
, vol.24
, Issue.11
, pp. 1377-1383
-
-
Ulmer, J.B.1
Valley, U.2
Rappuoli, R.3
-
4
-
-
46349091495
-
Adaptive clinical trials: Progress and challenges
-
Coffey CS, Kairalla JA. Adaptive clinical trials: Progress and challenges. Drugs R D 2008;9(4):229-42
-
(2008)
Drugs R D
, vol.9
, Issue.4
, pp. 229-242
-
-
Coffey, C.S.1
Kairalla, J.A.2
-
6
-
-
83255162440
-
Adaptive trial design could we use this approach to improve clinical trials in the field of global health?
-
Lang T. Adaptive trial design: Could we use this approach to improve clinical trials in the field of global health? Am J Trop Med Hyg 2011;85(6):967-70
-
(2011)
Am J Trop Med Hyg
, vol.85
, Issue.6
, pp. 967-970
-
-
Lang, T.1
-
7
-
-
79959338198
-
Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers
-
Swanson KA, Settembre EC, Shaw CA, et al. Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers. Proc Natl Acad Sci USA 2011;108(23):9619-24
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.23
, pp. 9619-9624
-
-
Swanson, K.A.1
Settembre, E.C.2
Shaw, C.A.3
-
9
-
-
84885706453
-
Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in hiv-1 envelope glycoprotein
-
Kassa A, Dey AK, Sarkar P, et al. Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein. PLoS One 2013;8(10):e76139
-
(2013)
PLoS One
, vol.8
, Issue.10
-
-
Kassa, A.1
Dey, A.K.2
Sarkar, P.3
-
10
-
-
79952140653
-
Influenza virus vaccine based on the conserved hemagglutinin stalk domain
-
Steel J, Lowen AC, Wang TT, et al. Influenza virus vaccine based on the conserved hemagglutinin stalk domain. MBio 2010;1:1
-
(2010)
MBio
, vol.1
, pp. 1
-
-
Steel, J.1
Lowen, A.C.2
Wang, T.T.3
-
13
-
-
71549122886
-
Determination of protein purity
-
Rhodes DG, Laue TM. Determination of protein purity. Methods Enzymol 2009;463: 677-89
-
(2009)
Methods Enzymol
, vol.463
, pp. 677-689
-
-
Rhodes, D.G.1
Laue, T.M.2
-
14
-
-
84940296065
-
Guideline on validation of the limulus amebocyte lysate test as an end-product endotoxin test for human and animal parenteral drugs, biological products, and medical devices
-
2011, Chapter 85, Bacterial Endotoxins Test 2011
-
Guideline on validation of the limulus amebocyte lysate test as an end-product endotoxin test for human and animal parenteral drugs, biological products, and medical devices 1987 United States Pharmacopeia (USP), 2011, Chapter , Bacterial Endotoxins Test 2011
-
(1987)
United States Pharmacopeia (USP
-
-
-
15
-
-
2642520417
-
Top-down proteomics
-
Kelleher NL. Top-down proteomics. Anal Chem 2004;76(11):197A-203A
-
(2004)
Anal Chem
, vol.76
, Issue.11
-
-
Kelleher, N.L.1
-
16
-
-
35848949043
-
Decoding protein modifications using top-down mass spectrometry
-
Siuti N and NL. Kelleher. Decoding protein modifications using top-down mass spectrometry. Nat Methods 2007;4(10): 817-21
-
(2007)
Nat Methods
, vol.4
, Issue.10
, pp. 817-821
-
-
Siuti, N.1
Kelleher, N.L.2
-
17
-
-
82955163228
-
Intact protein separation by chromatographic and/or electrophoretic techniques for top-down proteomics
-
Capriotti AL, Cavaliere C, Foglia P, et al. Intact protein separation by chromatographic and/or electrophoretic techniques for top-down proteomics. J Chromatogr A 2011;1218(49):8760-76
-
(2011)
J Chromatogr A
, vol.1218
, Issue.49
, pp. 8760-8776
-
-
Capriotti, A.L.1
Cavaliere, C.2
Foglia, P.3
-
18
-
-
84862543635
-
Simultaneous quantification of the viral antigens hemagglutinin and neuraminidase in influenza vaccines by LC-MSE
-
Creskey MC, Li C, Wang J, et al. Simultaneous quantification of the viral antigens hemagglutinin and neuraminidase in influenza vaccines by LC-MSE. Vaccine 2012;30(32):4762-70
-
(2012)
Vaccine
, vol.30
, Issue.32
, pp. 4762-4770
-
-
Creskey, M.C.1
Li, C.2
Wang, J.3
-
19
-
-
84858276194
-
Simultaneous quantification of hemagglutinin and neuraminidase of influenza virus using isotope dilution mass spectrometry
-
Williams TL, Pirkle JL, Barr JR. Simultaneous quantification of hemagglutinin and neuraminidase of influenza virus using isotope dilution mass spectrometry. Vaccine 2012;30(14):2475-82
-
(2012)
Vaccine
, vol.30
, Issue.14
, pp. 2475-2482
-
-
Williams, T.L.1
Pirkle, J.L.2
Barr, J.R.3
-
20
-
-
42649130016
-
Quantification of influenza virus hemagglutinins in complex mixtures using isotope dilution tandem mass spectrometry
-
Williams TL, Luna L, Guo Z, et al. Quantification of influenza virus hemagglutinins in complex mixtures using isotope dilution tandem mass spectrometry. Vaccine 2008;26(20):2510-20
-
(2008)
Vaccine
, vol.26
, Issue.20
, pp. 2510-2520
-
-
Williams, T.L.1
Luna, L.2
Guo, Z.3
-
21
-
-
0034100284
-
Contributions of mass spectrometry to structural immunology
-
Downard KM. Contributions of mass spectrometry to structural immunology. J Mass Spectrom 2000;35(4):493-503
-
(2000)
J Mass Spectrom
, vol.35
, Issue.4
, pp. 493-503
-
-
Downard, K.M.1
-
22
-
-
71549138062
-
Determination of size, molecular weight, and presence of subunits
-
Rhodes DG, Bossio RE, Laue TM. Determination of size, molecular weight, and presence of subunits. Methods Enzymol 2009;463:691-723
-
(2009)
Methods Enzymol
, vol.463
, pp. 691-723
-
-
Rhodes, D.G.1
Bossio, R.E.2
Laue, T.M.3
-
23
-
-
33749452453
-
A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation
-
Liu J, Andya JD, Shire SJ. A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation. Aaps J 2006;8(3): E580-9
-
(2006)
Aaps J
, vol.8
, Issue.3
-
-
Liu, J.1
Andya, J.D.2
Shire, S.J.3
-
24
-
-
0035870165
-
Matrix-Assisted laser desorption/ionization coupled with quadrupole/orthogonal acceleration time-of-flight mass spectrometry for protein discovery, identification, and structural analysis
-
Baldwin MA, Medzihradszky KF, Lock CM , et al. Matrix-Assisted laser desorption/ionization coupled with quadrupole/orthogonal acceleration time-of-flight mass spectrometry for protein discovery, identification, and structural analysis. Anal Chem 2001;73(8):1707-20
-
(2001)
Anal Chem
, vol.73
, Issue.8
, pp. 1707-1720
-
-
Baldwin, M.A.1
Medzihradszky, K.F.2
Lock, C.M.3
-
25
-
-
0035894420
-
Online size-exclusion highperformance liquid chromatography light scattering and differential refractometry methods to determine degree of polymer conjugation to proteins and protein-protein or protein-ligand association states
-
Kendrick BS, Kerwin BA, Chang BS, Philo JS. Online size-exclusion highperformance liquid chromatography light scattering and differential refractometry methods to determine degree of polymer conjugation to proteins and protein-protein or protein-ligand association states. Anal Biochem 2001;299(2):136-46
-
(2001)
Anal Biochem
, vol.299
, Issue.2
, pp. 136-146
-
-
Kendrick, B.S.1
Kerwin, B.A.2
Chang, B.S.3
Philo, J.S.4
-
26
-
-
0030571043
-
Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions
-
Wen J, Arakawa T, Philo JS. Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions. Anal Biochem 1996; 240(2):155-66
-
(1996)
Anal Biochem
, vol.240
, Issue.2
, pp. 155-166
-
-
Wen, J.1
Arakawa, T.2
Philo, J.S.3
-
27
-
-
33747175672
-
Simultaneous determination of protein aggregation, degradation, and absolute molecular weight by size exclusion chromatography-multiangle laser light scattering
-
Ye H. Simultaneous determination of protein aggregation, degradation, and absolute molecular weight by size exclusion chromatography-multiangle laser light scattering. Anal Biochem 2006;356(1): 76-85
-
(2006)
Anal Biochem
, vol.356
, Issue.1
, pp. 76-85
-
-
Ye, H.1
-
28
-
-
69249206868
-
A critical review of methods for size characterization of non-particulate protein aggregates
-
Philo JS. A critical review of methods for size characterization of non-particulate protein aggregates. Curr Pharm Biotechnol 2009;10(4):359-72
-
(2009)
Curr Pharm Biotechnol
, vol.10
, Issue.4
, pp. 359-372
-
-
Philo, J.S.1
-
29
-
-
33847683955
-
Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity
-
Gabrielson JP, Brader ML, Pekar AH, et al. Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity. J Pharm Sci 2007;96(2): 268-79
-
(2007)
J Pharm Sci
, vol.96
, Issue.2
, pp. 268-279
-
-
Gabrielson, J.P.1
Brader, M.L.2
Pekar, A.H.3
-
30
-
-
33748742268
-
Is any measurement method optimal for all aggregate sizes and types?
-
Philo JS. Is any measurement method optimal for all aggregate sizes and types? Aaps J 2006;8(3):E564-71
-
(2006)
Aaps J
, vol.8
, Issue.3
-
-
Philo, J.S.1
-
31
-
-
62749099087
-
Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality
-
Carpenter JF, Randolph TW, Jiskoot W, et al. Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality. J Pharm Sci 2009;98(4):1201-5
-
(2009)
J Pharm Sci
, vol.98
, Issue.4
, pp. 1201-1205
-
-
Carpenter, J.F.1
Randolph, T.W.2
Jiskoot, W.3
-
32
-
-
78649661342
-
Characterization of particles in protein solutions: Reaching the limits of current technologies
-
Demeule B, Messick S, Shire SJ, Liu J. Characterization of particles in protein solutions: Reaching the limits of current technologies. Aaps J 2010;12(4):708-15
-
(2010)
Aaps J
, vol.12
, Issue.4
, pp. 708-715
-
-
Demeule, B.1
Messick, S.2
Shire, S.J.3
Liu, J.4
-
33
-
-
84863218474
-
Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars
-
Berkowitz SA, Engen JR, Mazzeo JR, Jones GB. Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars. Nat Rev Drug Discov 2012; 11(7):527-40
-
(2012)
Nat Rev Drug Discov
, vol.11
, Issue.7
, pp. 527-540
-
-
Berkowitz, S.A.1
Engen, J.R.2
Mazzeo, J.R.3
Jones, G.B.4
-
34
-
-
84878149778
-
Characterization and quantitation of aggregates and particles in interferon-beta products: Potential links between product quality attributes and immunogenicity
-
Barnard JG, Babcock K, Carpenter JF. Characterization and quantitation of aggregates and particles in interferon-beta products: Potential links between product quality attributes and immunogenicity. J Pharm Sci 2013;102(3):915-28
-
(2013)
J Pharm Sci
, vol.102
, Issue.3
, pp. 915-928
-
-
Barnard, J.G.1
Babcock, K.2
Carpenter, J.F.3
-
35
-
-
84865353525
-
The future of protein particle characterization and understanding its potential to diminish the immunogenicity of biopharmaceuticals: A shared perspective
-
Bee JS, Goletz TJ, Ragheb JA. The future of protein particle characterization and understanding its potential to diminish the immunogenicity of biopharmaceuticals: A shared perspective. J Pharm Sci 2012; 101(10):3580-5
-
(2012)
J Pharm Sci
, vol.101
, Issue.10
, pp. 3580-3585
-
-
Bee, J.S.1
Goletz, T.J.2
Ragheb, J.A.3
-
37
-
-
0035287319
-
Factors affecting short-Term and long-Term stabilities of proteins
-
Arakawa T, Prestrelski SJ, Kenney WC, Carpenter JF. Factors affecting short-Term and long-Term stabilities of proteins. Adv Drug Deliv Rev 2001;46(1-3):307-26
-
(2001)
Adv Drug Deliv Rev
, vol.46
, Issue.1-3
, pp. 307-326
-
-
Arakawa, T.1
Prestrelski, S.J.2
Kenney, W.C.3
Carpenter, J.F.4
-
39
-
-
0030770631
-
Rational design of stable lyophilized protein formulations: Some practical advice
-
Carpenter JF, Pikal MJ, Chang BS, Randolph TW. Rational design of stable lyophilized protein formulations: Some practical advice. Pharm Res 1997;14(8): 969-75
-
(1997)
Pharm Res
, vol.14
, Issue.8
, pp. 969-975
-
-
Carpenter, J.F.1
Pikal, M.J.2
Chang, B.S.3
Randolph, T.W.4
-
40
-
-
0141567459
-
Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation
-
Chi EY, Krishnan S, Randolph TW, Carpenter JF. Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation. Pharm Res 2003;20(9):1325-36
-
(2003)
Pharm Res
, vol.20
, Issue.9
, pp. 1325-1336
-
-
Chi, E.Y.1
Krishnan, S.2
Randolph, T.W.3
Carpenter, J.F.4
-
41
-
-
0025732448
-
Protein-solvent interactions in pharmaceutical formulations
-
Arakawa T, Kita Y, Carpenter JF. Protein-solvent interactions in pharmaceutical formulations. Pharm Res 1991;8(3):285-91
-
(1991)
Pharm Res
, vol.8
, Issue.3
, pp. 285-291
-
-
Arakawa, T.1
Kita, Y.2
Carpenter, J.F.3
-
42
-
-
0026493277
-
Interactions of stabilizing additives with proteins during freeze-Thawing and freeze-drying
-
225-38; discussion
-
Carpenter JF, Arakawa T, Crowe JH. Interactions of stabilizing additives with proteins during freeze-Thawing and freeze-drying. Dev Biol Stand 1992;74: 225-38; discussion 238-9
-
(1992)
Dev Biol Stand
, vol.74
, pp. 238-239
-
-
Carpenter, J.F.1
Arakawa, T.2
Crowe, J.H.3
-
43
-
-
0025019350
-
Conformational stability of globular proteins
-
Pace N. Conformational stability of globular proteins. Trends Biochem Sci 1970;15: 14-17
-
(1970)
Trends Biochem Sci
, vol.15
, pp. 14-17
-
-
Pace, N.1
-
44
-
-
0023659990
-
Stabilization of phosphofructokinase with sugars during freeze-drying: Characterization of enhanced protection in the presence of divalent cations
-
Carpenter JF, Crowe LM, Crowe JH. Stabilization of phosphofructokinase with sugars during freeze-drying: Characterization of enhanced protection in the presence of divalent cations. Biochim Biophys Acta 1987;923(1):109-15
-
(1987)
Biochim Biophys Acta
, vol.923
, Issue.1
, pp. 109-115
-
-
Carpenter, J.F.1
Crowe, L.M.2
Crowe, J.H.3
-
45
-
-
0023905575
-
The mechanism of cryoprotection of proteins by solutes
-
Carpenter JF, Crowe JH. The mechanism of cryoprotection of proteins by solutes. Cryobiology 1988;25(3):244-55
-
(1988)
Cryobiology
, vol.25
, Issue.3
, pp. 244-255
-
-
Carpenter, J.F.1
Crowe, J.H.2
-
46
-
-
1242314686
-
Design of freeze-drying processes for pharmaceuticals: Practical advice
-
Tang X, Pikal MJ. Design of freeze-drying processes for pharmaceuticals: Practical advice. Pharm Res 2004;21(2):191-200
-
(2004)
Pharm Res
, vol.21
, Issue.2
, pp. 191-200
-
-
Tang, X.1
Pikal, M.J.2
-
47
-
-
0023696310
-
Long-Term preservation of dried phosphofructokinase by sugars and sugar/zinc mixtures
-
Carpenter JF, Martin B, Loomis SH, Crowe JH. Long-Term preservation of dried phosphofructokinase by sugars and sugar/zinc mixtures. Cryobiology 1988;25(4): 372-6
-
(1988)
Cryobiology
, vol.25
, Issue.4
, pp. 372-376
-
-
Carpenter, J.F.1
Martin, B.2
Loomis, S.H.3
Crowe, J.H.4
-
48
-
-
0018789680
-
Increased thermal stability of proteins in the presence of sugars and polyols
-
Back JF, Oakenfull D, Smith MB. Increased thermal stability of proteins in the presence of sugars and polyols. Biochemistry 1979; 18(23):5191-6
-
(1979)
Biochemistry
, vol.18
, Issue.23
, pp. 5191-5196
-
-
Back, J.F.1
Oakenfull, D.2
Smith, M.B.3
-
49
-
-
0020546424
-
Increased thermal stability of collagen in the presence of sugars and polyols
-
Gekko K, Koga S. Increased thermal stability of collagen in the presence of sugars and polyols. J Biochem 1983;94(1):199-205
-
(1983)
J Biochem
, vol.94
, Issue.1
, pp. 199-205
-
-
Gekko, K.1
Koga, S.2
-
50
-
-
0024549238
-
An infrared spectroscopic study of the interactions of carbohydrates with dried proteins
-
Carpenter JF, Crowe JH. An infrared spectroscopic study of the interactions of carbohydrates with dried proteins. Biochemistry 1989;28(9):3916-22
-
(1989)
Biochemistry
, vol.28
, Issue.9
, pp. 3916-3922
-
-
Carpenter, J.F.1
Crowe, J.H.2
-
51
-
-
57349123585
-
Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations
-
Roy S, Henderson I, Nayar R, et al. Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations. J Pharm Sci 2008;97(12): 5132-46
-
(2008)
J Pharm Sci
, vol.97
, Issue.12
, pp. 5132-5146
-
-
Roy, S.1
Henderson, I.2
Nayar, R.3
-
52
-
-
33645456486
-
-
In: Carpenter JF Manning MC editors. Rational design of stable protein formulation. Kluwer Academic, NY,USA
-
Chang BS, Hershenson S. Practical approaches to protein formulation development. In: Carpenter JF, Manning MC, editors. Rational design of stable protein formulation. Kluwer Academic, NY,USA; 2002,.
-
(2002)
Practical Approaches to Protein Formulation Development
-
-
Chang, B.S.1
Hershenson, S.2
-
53
-
-
84885939872
-
Recent advances and further challenges in lyophilization
-
Kasper JC, Winter G, Friess W. Recent advances and further challenges in lyophilization. Eur J Pharm Biopharm 2013;85(2):162-9
-
(2013)
Eur J Pharm Biopharm
, vol.85
, Issue.2
, pp. 162-169
-
-
Kasper, J.C.1
Winter, G.2
Friess, W.3
-
55
-
-
33947203155
-
Drying-induced variations in physicochemical properties of amorphous pharmaceuticals and their impact on Stability II: Stability of a vaccine
-
Abdul-Fattah AM, Truong-Le V, Yee L, et al. Drying-induced variations in physicochemical properties of amorphous pharmaceuticals and their impact on Stability II: Stability of a vaccine. Pharm Res 2007;24(4):715-27
-
(2007)
Pharm Res
, vol.24
, Issue.4
, pp. 715-727
-
-
Abdul-Fattah, A.M.1
Truong-Le, V.2
Yee, L.3
-
56
-
-
33947287573
-
Drying-induced variations in physicochemical properties of amorphous pharmaceuticals and their impact on stability I): Stability of a monoclonal antibody
-
Abdul-Fattah AM, Truong-Le V, Yee L, et al. Drying-induced variations in physicochemical properties of amorphous pharmaceuticals and their impact on stability (I): Stability of a monoclonal antibody. J Pharm Sci 2007;96(8): 1983-2008
-
(2007)
J Pharm Sci
, vol.96
, Issue.8
, pp. 1983-2008
-
-
Abdul-Fattah, A.M.1
Truong-Le, V.2
Yee, L.3
-
57
-
-
84885835306
-
Lyophilization process design space
-
Patel SM, Pikal MJ. Lyophilization process design space. J Pharm Sci 2013;102(11): 3883-7
-
(2013)
J Pharm Sci
, vol.102
, Issue.11
, pp. 3883-3887
-
-
Patel, S.M.1
Pikal, M.J.2
-
58
-
-
84885937804
-
Meeting the challenges in freeze-drying of pharmaceuticals and biologicals
-
Friess W, Winter G. Meeting the challenges in freeze-drying of pharmaceuticals and biologicals. Eur J Pharm Biopharm 2013; 85(2):161
-
(2013)
Eur J Pharm Biopharm
, vol.85
, Issue.2
, pp. 161
-
-
Friess, W.1
Winter, G.2
-
59
-
-
84855878469
-
An empirical phase diagram/high throughput screening approach to the characterization and formulation of biopharmaceuticals
-
Jameel F Hershenson S editor. John Wiley & Sons Hoboken, NJ, USA
-
Joshi SB, Bhambhani A, Zeng Y, Middaugh CR. An empirical phase diagram/high throughput screening approach to the characterization and formulation of biopharmaceuticals. Formulation and process development strategies for manufacturing biopharmaceuticals. Jameel F, Hershenson S, editor. John Wiley & Sons; Hoboken, NJ, USA: 2010. p. 173-204
-
(2010)
Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals
, pp. 173-204
-
-
Joshi, S.B.1
Bhambhani, A.2
Zeng, Y.3
Middaugh, C.R.4
-
60
-
-
84859769263
-
An improved methodology for multidimensional high-Throughput preformulation characterization of protein conformational stability
-
Maddux NR, Rosen IT, Hu L, et al. An improved methodology for multidimensional high-Throughput preformulation characterization of protein conformational stability. J Pharm Sci 2012; 101(6):2017-24
-
(2012)
J Pharm Sci
, vol.101
, Issue.6
, pp. 2017-2024
-
-
Maddux, N.R.1
Rosen, I.T.2
Hu, L.3
-
61
-
-
84872502459
-
Physical characterization and formulation development of a recombinant pneumolysoid protein-based pneumococcal vaccine
-
Hu L, Joshi SB, Liyanage MR, et al. Physical characterization and formulation development of a recombinant pneumolysoid protein-based pneumococcal vaccine. J Pharm Sci 2013;102(2):387-400
-
(2013)
J Pharm Sci
, vol.102
, Issue.2
, pp. 387-400
-
-
Hu, L.1
Joshi, S.B.2
Liyanage, M.R.3
-
62
-
-
33745359812
-
A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine
-
Peek LJ, Brandau DT, Jones LS, et al. A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine. Vaccine 2006;24(31-32):5839-51
-
(2006)
Vaccine
, vol.24
, Issue.31-32
, pp. 5839-5851
-
-
Peek, L.J.1
Brandau, D.T.2
Jones, L.S.3
-
63
-
-
0032564304
-
Temperature-induced conformational transition of intestinal fatty acid binding protein enhancing ligand binding: A functional, spectroscopic, and molecular modeling study
-
Arighi CN, Rossi JP, Delfino JM. Temperature-induced conformational transition of intestinal fatty acid binding protein enhancing ligand binding: A functional, spectroscopic, and molecular modeling study. Biochemistry 1998;37(47): 16802-14
-
(1998)
Biochemistry
, vol.37
, Issue.47
, pp. 16802-16814
-
-
Arighi, C.N.1
Rossi, J.P.2
Delfino, J.M.3
-
64
-
-
0038309550
-
Protein stability induced by ligand binding correlates with changes in protein flexibility
-
Celej MS, Montich GG, Fidelio GD. Protein stability induced by ligand binding correlates with changes in protein flexibility. Protein Sci 2003;12(7):1496-506
-
(2003)
Protein Sci
, vol.12
, Issue.7
, pp. 1496-1506
-
-
Celej, M.S.1
Montich, G.G.2
Fidelio, G.D.3
-
65
-
-
0031972919
-
1-Anilino-8-naphthalene sulfonate anion-protein binding depends primarily on ion pair formation
-
Matulis D, Lovrien R. 1-Anilino-8-naphthalene sulfonate anion-protein binding depends primarily on ion pair formation. Biophys J 1998;74(1):422-9
-
(1998)
Biophys J
, vol.74
, Issue.1
, pp. 422-429
-
-
Matulis, D.1
Lovrien, R.2
-
66
-
-
84870690077
-
Comparative signature diagrams to evaluate biophysical data for differences in protein structure across various formulations
-
Iyer V, Maddux N, Hu L, et al. Comparative signature diagrams to evaluate biophysical data for differences in protein structure across various formulations. J Pharm Sci 2013;102(1):43-51
-
(2013)
J Pharm Sci
, vol.102
, Issue.1
, pp. 43-51
-
-
Iyer, V.1
Maddux, N.2
Hu, L.3
-
67
-
-
80054717076
-
Protein-excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development
-
Kamerzell TJ, Esfandiary R, Joshi SB, et al. Protein-excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development. Adv Drug Deliv Rev 2011;63(13):1118-59
-
(2011)
Adv Drug Deliv Rev
, vol.63
, Issue.13
, pp. 1118-1159
-
-
Kamerzell, T.J.1
Esfandiary, R.2
Joshi, S.B.3
-
68
-
-
35349028297
-
GlaxoSmithKline Adjuvant Systems in vaccines: Concepts, achievements and perspectives
-
Garcon N, Chomez P, Van Mechelen M. GlaxoSmithKline Adjuvant Systems in vaccines: Concepts, achievements and perspectives. Expert Rev Vaccines 2007;6(5): 723-39
-
(2007)
Expert Rev Vaccines
, vol.6
, Issue.5
, pp. 723-739
-
-
Garcon, N.1
Chomez, P.2
Van Mechelen, M.3
-
69
-
-
82255175484
-
Vaccines for the twenty-first century society
-
Rappuoli R, Mandl CW, Black S, De Gregorio E. Vaccines for the twenty-first century society. Nat Rev Immunol 2011; 11(12):865-72
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 865-872
-
-
Rappuoli, R.1
Mandl, C.W.2
Black, S.3
De Gregorio, E.4
-
70
-
-
77955647584
-
Principles of vaccine design-Lessons from nature
-
Zepp F. Principles of vaccine design-Lessons from nature. Vaccine 2010;28(Suppl 3): C14-24
-
(2010)
Vaccine
, vol.28
, Issue.SUPPL. 3
-
-
Zepp, F.1
-
72
-
-
0025695971
-
Aluminum compounds used as adjuvants in vaccines
-
Shirodkar S, Hutchinson RL, Perry DL, et al. Aluminum compounds used as adjuvants in vaccines. Pharm Res 1990; 7(12):1282-8
-
(1990)
Pharm Res
, vol.7
, Issue.12
, pp. 1282-1288
-
-
Shirodkar, S.1
Hutchinson, R.L.2
Perry, D.L.3
-
73
-
-
78650555727
-
Vaccines with aluminum-containing adjuvants: Optimizing vaccine efficacy and thermal stability
-
Clapp T, Siebert P, Chen D, Jones Braun L. Vaccines with aluminum-containing adjuvants: Optimizing vaccine efficacy and thermal stability. J Pharm Sci 2011;100(2): 388-401
-
(2011)
J Pharm Sci
, vol.100
, Issue.2
, pp. 388-401
-
-
Clapp, T.1
Siebert, P.2
Chen, D.3
Jones Braun, L.4
-
74
-
-
0025959504
-
Predicting the adsorption of proteins by aluminium-containing adjuvants
-
Seeber SJ, White JL, Hem SL. Predicting the adsorption of proteins by aluminium-containing adjuvants. Vaccine 1991;9(3):201-3
-
(1991)
Vaccine
, vol.9
, Issue.3
, pp. 201-203
-
-
Seeber, S.J.1
White, J.L.2
Hem, S.L.3
-
75
-
-
2342629345
-
Distribution of adsorbed antigen in mono-valent and combination vaccines
-
Morefield GL, HogenEsch H, Robinson JP, Hem SL. Distribution of adsorbed antigen in mono-valent and combination vaccines. Vaccine 2004;22(15-16):1973-84
-
(2004)
Vaccine
, vol.22
, Issue.15-16
, pp. 1973-1984
-
-
Morefield, G.L.1
Hogenesch, H.2
Robinson, J.P.3
Hem, S.L.4
-
76
-
-
0021326495
-
Characterization of aluminum hydroxide for use as an adjuvant in parenteral vaccines
-
Hem SL, White JL. Characterization of aluminum hydroxide for use as an adjuvant in parenteral vaccines. J Parenter Sci Technol 1984;38(1):2-10
-
(1984)
J Parenter Sci Technol
, vol.38
, Issue.1
, pp. 2-10
-
-
Hem, S.L.1
White, J.L.2
-
77
-
-
0034577642
-
Characterization of aluminium-containing adjuvants
-
White JL, Hem SL. Characterization of aluminium-containing adjuvants. Dev Biol (Basel) 2000;103:217-28
-
(2000)
Dev Biol (Basel
, vol.103
, pp. 217-228
-
-
White, J.L.1
Hem, S.L.2
-
78
-
-
35348968868
-
Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation
-
Hem SL, Hogenesch H. Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation. Expert Rev Vaccines 2007;6(5):685-98
-
(2007)
Expert Rev Vaccines
, vol.6
, Issue.5
, pp. 685-698
-
-
Hem, S.L.1
Hogenesch, H.2
-
80
-
-
34748895084
-
Effects of solution conditions and surface chemistry on the adsorption of three recombinant botulinum neurotoxin antigens to aluminum salt adjuvants
-
Vessely C, Estey T, Randolph TW, et al. Effects of solution conditions and surface chemistry on the adsorption of three recombinant botulinum neurotoxin antigens to aluminum salt adjuvants. J Pharm Sci 2007;96(9):2375-89
-
(2007)
J Pharm Sci
, vol.96
, Issue.9
, pp. 2375-2389
-
-
Vessely, C.1
Estey, T.2
Randolph, T.W.3
-
81
-
-
84885378665
-
Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant
-
Hafner AM, Corthesy B, Merkle HP. Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant. Adv Drug Deliv Rev 2013;65(10):1386-99
-
(2013)
Adv Drug Deliv Rev
, vol.65
, Issue.10
, pp. 1386-1399
-
-
Hafner, A.M.1
Corthesy, B.2
Merkle, H.P.3
-
82
-
-
0037654710
-
Microparticles as vaccine adjuvants and delivery systems
-
O'Hagan DT, Singh M. Microparticles as vaccine adjuvants and delivery systems. Expert Rev Vaccines 2003;2(2):269-83
-
(2003)
Expert Rev Vaccines
, vol.2
, Issue.2
, pp. 269-283
-
-
O'hagan, D.T.1
Singh, M.2
-
83
-
-
35349027729
-
Nanoparticles and microparticles as vaccine-delivery systems
-
Singh M, Chakrapani A, O'Hagan D. Nanoparticles and microparticles as vaccine-delivery systems. Expert Rev Vaccines 2007;6(5):797-808
-
(2007)
Expert Rev Vaccines
, vol.6
, Issue.5
, pp. 797-808
-
-
Singh, M.1
Chakrapani, A.2
O'hagan, D.3
-
84
-
-
79952362612
-
Adjuvant system AS03 containing alpha-Tocopherol modulates innate immune response and leads to improved adaptive immunity
-
Morel S, Didierlaurent A, Bourguignon P, et al. Adjuvant system AS03 containing alpha-Tocopherol modulates innate immune response and leads to improved adaptive immunity. Vaccine 2011;29(13):2461-73
-
(2011)
Vaccine
, vol.29
, Issue.13
, pp. 2461-2473
-
-
Morel, S.1
Didierlaurent, A.2
Bourguignon, P.3
-
85
-
-
84879880507
-
The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation none of the individual components induce a comparable adjuvant effect
-
Calabro S, Tritto E, Pezzotti A, et al. The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect. Vaccine 2013; 31(33):3363-9
-
(2013)
Vaccine
, vol.31
, Issue.33
, pp. 3363-3369
-
-
Calabro, S.1
Tritto, E.2
Pezzotti, A.3
-
86
-
-
84871578453
-
The history of MF59((R)) adjuvant: A phoenix that arose from the ashes
-
O'Hagan DT, Ott GS, Nest GV, et al. The history of MF59((R)) adjuvant: A phoenix that arose from the ashes. Expert Rev Vaccines 2013;12(1):13-30
-
(2013)
Expert Rev Vaccines
, vol.12
, Issue.1
, pp. 13-30
-
-
O'hagan, D.T.1
Ott, G.S.2
Nest, G.V.3
-
87
-
-
84884249524
-
Fluad(R)-MF59(R)-Adjuvanted influenza vaccine in older adults
-
Tsai TF. Fluad(R)-MF59(R)-Adjuvanted influenza vaccine in older adults. Infect Chemother 2013;45(2):159-74
-
(2013)
Infect Chemother
, vol.45
, Issue.2
, pp. 159-174
-
-
Tsai, T.F.1
-
88
-
-
0038330442
-
MF59-Adjuvanted vaccines: Increased immunogenicity with an optimal safety profile
-
Podda A, Del Giudice G. MF59-Adjuvanted vaccines: Increased immunogenicity with an optimal safety profile. Expert Rev Vaccines 2003;2(2):197-203
-
(2003)
Expert Rev Vaccines
, vol.2
, Issue.2
, pp. 197-203
-
-
Podda, A.1
Del Giudice, G.2
-
89
-
-
0038176089
-
Montanide ISA 720 and 51: A new generation of water in oil emulsions as adjuvants for human vaccines
-
Aucouturier J, Dupuis L, Deville S, et al. Montanide ISA 720 and 51: A new generation of water in oil emulsions as adjuvants for human vaccines. Expert Rev Vaccines 2002;1(1):111-18
-
(2002)
Expert Rev Vaccines
, vol.1
, Issue.1
, pp. 111-118
-
-
Aucouturier, J.1
Dupuis, L.2
Deville, S.3
-
90
-
-
0032724999
-
Squalene and squalane emulsions as adjuvants
-
Allison AC. Squalene and squalane emulsions as adjuvants. Methods 1999; 19(1):87-93
-
(1999)
Methods
, vol.19
, Issue.1
, pp. 87-93
-
-
Allison, A.C.1
-
91
-
-
0032706419
-
Oil-in-water liposomal emulsions: Characterization and potential use in vaccine delivery
-
Muderhwa JM, Matyas GR, Spitler LE, Alving CR. Oil-in-water liposomal emulsions: Characterization and potential use in vaccine delivery. J Pharm Sci 1999; 88(12):1332-9
-
(1999)
J Pharm Sci
, vol.88
, Issue.12
, pp. 1332-1339
-
-
Muderhwa, J.M.1
Matyas, G.R.2
Spitler, L.E.3
Alving, C.R.4
-
92
-
-
84865294719
-
Characterization of surfactants in an oil-in-water emulsion-based vaccine adjuvant using MS and HPLC-MS: Structural analysis and quantification
-
Cotte JF, Sonnery S, Martial F, et al. Characterization of surfactants in an oil-in-water emulsion-based vaccine adjuvant using MS and HPLC-MS: Structural analysis and quantification. Int J Pharm 2012;436(1-2):233-9
-
(2012)
Int J Pharm
, vol.436
, Issue.1-2
, pp. 233-239
-
-
Cotte, J.F.1
Sonnery, S.2
Martial, F.3
-
93
-
-
0024455465
-
Formulation of vaccine adjuvant muramyldipeptides. 3 Processing optimization, characterization, and bioactivity of an emulsion vehicle
-
Lidgate DM, Fu RC, Byars NE, et al. Formulation of vaccine adjuvant muramyldipeptides. 3. Processing optimization, characterization, and bioactivity of an emulsion vehicle. Pharm Res 1989;6(9):748-52
-
(1989)
Pharm Res
, vol.6
, Issue.9
, pp. 748-752
-
-
Lidgate, D.M.1
Fu, R.C.2
Byars, N.E.3
-
94
-
-
44749087196
-
Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions
-
Fox CB, Anderson RC, Dutill TS, et al. Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions. Colloids Surf B Biointerfaces 2008;65(1):98-105
-
(2008)
Colloids Surf B Biointerfaces
, vol.65
, Issue.1
, pp. 98-105
-
-
Fox, C.B.1
Anderson, R.C.2
Dutill, T.S.3
-
95
-
-
31644446786
-
Encapsulation of the immune potentiators MPL and RC529 in PLG microparticles enhances their potency
-
Kazzaz J, Singh M, Ugozzoli M, et al. Encapsulation of the immune potentiators MPL and RC529 in PLG microparticles enhances their potency. J Control Release 2006;110(3):566-73
-
(2006)
J Control Release
, vol.110
, Issue.3
, pp. 566-573
-
-
Kazzaz, J.1
Singh, M.2
Ugozzoli, M.3
-
96
-
-
17644416719
-
Targeting the innate immune response with improved vaccine adjuvants
-
Suppl
-
Pashine A, Valiante NM, Ulmer JB. Targeting the innate immune response with improved vaccine adjuvants. Nat Med 2005; 11(4 Suppl):S63-8
-
(2005)
Nat Med
, vol.11
, Issue.4
-
-
Pashine, A.1
Valiante, N.M.2
Ulmer, J.B.3
-
97
-
-
84889367411
-
-
In Singh M, editor. Vaccine adjuvants and delivery systems. John Wiley & Sons, Inc., Hoboken, NJ, USA
-
Xu F, Valiante NM, Ulmer JB. Small molecule immunopotentiators as vaccine adjuvants. In: Singh M, editor. Vaccine adjuvants and delivery systems. John Wiley & Sons, Inc., Hoboken, NJ, USA: 2006
-
(2006)
Small Molecule Immunopotentiators As Vaccine Adjuvants
-
-
Xu, F.1
Valiante, N.M.2
Ulmer, J.B.3
-
98
-
-
79954582124
-
TLR-based immune adjuvants
-
Steinhagen F, Kinjo T, Bode C, Klinman DM. TLR-based immune adjuvants. Vaccine 2011;29(17):3341-55
-
(2011)
Vaccine
, vol.29
, Issue.17
, pp. 3341-3355
-
-
Steinhagen, F.1
Kinjo, T.2
Bode, C.3
Klinman, D.M.4
-
99
-
-
68949113643
-
Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution
-
Vessely C, Estey T, Randolph TW, et al. Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution. J Pharm Sci 2009;98(9):2970-93
-
(2009)
J Pharm Sci
, vol.98
, Issue.9
, pp. 2970-2993
-
-
Vessely, C.1
Estey, T.2
Randolph, T.W.3
-
100
-
-
79958819334
-
Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum-containing adjuvants on the immune response
-
Hansen B, Malyala P, Singh M, et al. Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum-containing adjuvants on the immune response. J Pharm Sci 2011;100(8):3245-50
-
(2011)
J Pharm Sci
, vol.100
, Issue.8
, pp. 3245-3250
-
-
Hansen, B.1
Malyala, P.2
Singh, M.3
-
101
-
-
68949113643
-
Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution
-
Vessely C, Estey T, Randolph TW, et al. Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution. J Pharm Sci 2009;98(9):2970-93
-
(2009)
J Pharm Sci
, vol.98
, Issue.9
, pp. 2970-2993
-
-
Vessely, C.1
Estey, T.2
Randolph, T.W.3
-
102
-
-
84355161418
-
Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer
-
Zhu D, Huang S, McClellan H, et al. Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer. Vaccine 2012;30(2):189-94
-
(2012)
Vaccine
, vol.30
, Issue.2
, pp. 189-194
-
-
Zhu, D.1
Huang, S.2
McClellan, H.3
-
103
-
-
70349298331
-
Use of o-phthalaldehyde assay to determine protein contents of Alhydrogel-based vaccines
-
Zhu D, Saul A, Huang S, et al. Use of o-phthalaldehyde assay to determine protein contents of Alhydrogel-based vaccines. Vaccine 2009;27(43):6054-9
-
(2009)
Vaccine
, vol.27
, Issue.43
, pp. 6054-6059
-
-
Zhu, D.1
Saul, A.2
Huang, S.3
-
104
-
-
65049091202
-
Development of a direct alhydrogel formulation immunoassay (dafia)
-
Zhu D, Huang S, Gebregeorgis E, et al. Development of a Direct Alhydrogel Formulation Immunoassay (DAFIA). J Immunol Methods 2009;344(1):73-8
-
(2009)
J Immunol Methods
, vol.344
, Issue.1
, pp. 73-78
-
-
Zhu, D.1
Huang, S.2
Gebregeorgis, E.3
-
105
-
-
85017622871
-
-
In: Mannhold R, Kubinyi H, Folkers G, editors. Methods and principles in medicinal chemistry: Drug bioavailability John Wiley & Sons, Inc., Hoboken, NJ, USA
-
Colclough N, Ruston L, Tam K. Aqueous solubility in drug discovery chemistry, DMPK, and biological assays. In: Mannhold R, Kubinyi H, Folkers G, editors. Methods and principles in medicinal chemistry: Drug bioavailability John Wiley & Sons, Inc., Hoboken, NJ, USA: 2009
-
(2009)
Aqueous Solubility in Drug Discovery Chemistry, DMPK, and Biological Assays
-
-
Colclough, N.1
Ruston, L.2
Tam, K.3
-
106
-
-
17644426636
-
Concentration determination of a recombinant vaccine antigen adsorbed onto an alum adjuvant by chemiluminescent nitrogen detection
-
Amari JV, Levesque P, Lian Z, et al. Concentration determination of a recombinant vaccine antigen adsorbed onto an alum adjuvant by chemiluminescent nitrogen detection. Pharm Res 2005;22(1): 33-7
-
(2005)
Pharm Res
, vol.22
, Issue.1
, pp. 33-37
-
-
Amari, J.V.1
Levesque, P.2
Lian, Z.3
-
107
-
-
80052722266
-
Flow cytometry: An alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant
-
Ugozzoli M, Laera D, Nuti S, et al. Flow cytometry: An alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant. Anal Biochem 2011;418(2):224-30
-
(2011)
Anal Biochem
, vol.418
, Issue.2
, pp. 224-230
-
-
Ugozzoli, M.1
Laera, D.2
Nuti, S.3
-
108
-
-
84863643546
-
Adjuvant properties of mesoporous silica particles tune the development of effector T cells
-
Vallhov H, Kupferschmidt N, Gabrielsson S, et al. Adjuvant properties of mesoporous silica particles tune the development of effector T cells. Small 2012;8(13):2116-24
-
(2012)
Small
, vol.8
, Issue.13
, pp. 2116-2124
-
-
Vallhov, H.1
Kupferschmidt, N.2
Gabrielsson, S.3
-
109
-
-
33845187202
-
Potentiation of the immune response to non-Adsorbed antigens by aluminum-containing adjuvants
-
Romero Mendez IZ, Shi Y, HogenEsch H, Hem SL. Potentiation of the immune response to non-Adsorbed antigens by aluminum-containing adjuvants. Vaccine 2007;25(5):825-33
-
(2007)
Vaccine
, vol.25
, Issue.5
, pp. 825-833
-
-
Romero Mendez, I.Z.1
Shi, Y.2
Hogenesch, H.3
Hem, S.L.4
-
110
-
-
47549086337
-
Determination of adsorbed protein concentration in aluminum hydroxide suspensions by near-infrared transmittance spectroscopy
-
Lai X, Zheng Y, Jacobsen S, et al. Determination of adsorbed protein concentration in aluminum hydroxide suspensions by near-infrared transmittance spectroscopy. Appl Spectrosc 2008;62(7): 784-90
-
(2008)
Appl Spectrosc
, vol.62
, Issue.7
, pp. 784-790
-
-
Lai, X.1
Zheng, Y.2
Jacobsen, S.3
-
111
-
-
70449627069
-
Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations
-
Anderson RC, Fox CB, Dutill TS, et al. Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations. Colloids Surf B Biointerfaces 2010;75(1):123-32
-
(2010)
Colloids Surf B Biointerfaces
, vol.75
, Issue.1
, pp. 123-132
-
-
Anderson, R.C.1
Fox, C.B.2
Dutill, T.S.3
-
113
-
-
84894456418
-
Modulating potency: Physicochemical characteristics are a determining factor of TLR4-Agonist nanosuspension activity
-
Epub ahead of print]
-
Dowling QM, Sivananthan SJ, Guderian JA, et al. Modulating potency: Physicochemical characteristics are a determining factor of TLR4-Agonist nanosuspension activity. J Pharm Sci 2014. [Epub ahead of print]
-
(2014)
J Pharm Sci
-
-
Dowling, Q.M.1
Sivananthan, S.J.2
Guderian, J.A.3
-
114
-
-
58249106119
-
Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune response
-
Hansen B, Belfast M, Soung G, et al. Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune response. Vaccine 2009;27(6):888-92
-
(2009)
Vaccine
, vol.27
, Issue.6
, pp. 888-892
-
-
Hansen, B.1
Belfast, M.2
Soung, G.3
-
115
-
-
67349137094
-
Relationship between tightness of binding and immunogenicity in an aluminum-containing adjuvant-Adsorbed hepatitis B vaccine
-
Egan PM, Belfast MT, Gimenez JA, et al. Relationship between tightness of binding and immunogenicity in an aluminum-containing adjuvant-Adsorbed hepatitis B vaccine. Vaccine 2009;27(24): 3175-80
-
(2009)
Vaccine
, vol.27
, Issue.24
, pp. 3175-3180
-
-
Egan, P.M.1
Belfast, M.T.2
Gimenez, J.A.3
-
116
-
-
70350712151
-
Vaccine stability study design and analysis to support product licensure
-
387-96; discussion
-
Schofield TL. Vaccine stability study design and analysis to support product licensure. Biologicals 2009;37(6):387-96; discussion 421-3
-
(2009)
Biologicals
, vol.37
, Issue.6
, pp. 421-423
-
-
Schofield, T.L.1
-
117
-
-
70449533155
-
Goals of stability evaluation throughout the vaccine life cycle
-
369-78; discussion
-
Krause PR. Goals of stability evaluation throughout the vaccine life cycle. Biologicals 2009;37(6):369-78; discussion 421-3
-
(2009)
Biologicals
, vol.37
, Issue.6
, pp. 421-423
-
-
Krause, P.R.1
-
118
-
-
77449158532
-
Guidelines on stability evaluation of vaccines
-
424-34; discussion
-
Dobbelaer R, Pfleiderer M, Haase M, et al. Guidelines on stability evaluation of vaccines. Biologicals 2009;37(6):424-34; discussion 421-3
-
(2009)
Biologicals
, vol.37
, Issue.6
, pp. 421-423
-
-
Dobbelaer, R.1
Pfleiderer, M.2
Haase, M.3
-
119
-
-
70350759648
-
Stability evaluation of vaccines
-
Schofield T, Krause PR. Stability evaluation of vaccines. Biologicals 2009;37(6):355
-
(2009)
Biologicals
, vol.37
, Issue.6
, pp. 355
-
-
Schofield, T.1
Krause, P.R.2
-
120
-
-
70350714256
-
Basic principles of stability
-
379-86; discussion
-
Egan W, Schofield T. Basic principles of stability. Biologicals 2009;37(6):379-86; discussion 421-3
-
(2009)
Biologicals
, vol.37
, Issue.6
, pp. 421-423
-
-
Egan, W.1
Schofield, T.2
-
121
-
-
84859393693
-
Immune-correlates analysis of an HIV-1 vaccine efficacy trial
-
Haynes BF, Gilbert PB, McElrath MJ, et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012;366(14):1275-86
-
(2012)
N Engl J Med
, vol.366
, Issue.14
, pp. 1275-1286
-
-
Haynes, B.F.1
Gilbert, P.B.2
McElrath, M.J.3
-
122
-
-
84872809067
-
Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2
-
Liao HX, Bonsignori M, Alam SM, et al. Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity 2013; 38(1):176-86
-
(2013)
Immunity
, vol.38
, Issue.1
, pp. 176-186
-
-
Liao, H.X.1
Bonsignori, M.2
Alam, S.M.3
-
123
-
-
53549116738
-
The complex inter-relationships between protein flexibility and stability
-
Kamerzell TJ, Middaugh CR. The complex inter-relationships between protein flexibility and stability. J Pharm Sci 2008;97(9): 3494-517
-
(2008)
J Pharm Sci
, vol.97
, Issue.9
, pp. 3494-3517
-
-
Kamerzell, T.J.1
Middaugh, C.R.2
-
125
-
-
84893641670
-
High-Throughput biophysical analysis of protein therapeutics to examine interrelationships between aggregate formation and conformational stability
-
Chaudhuri R, Cheng Y, Middaugh CR, Volkin DB. High-Throughput biophysical analysis of protein therapeutics to examine interrelationships between aggregate formation and conformational stability. Aaps J 2014;16(1):48-64
-
(2014)
Aaps J
, vol.16
, Issue.1
, pp. 48-64
-
-
Chaudhuri, R.1
Cheng, Y.2
Middaugh, C.R.3
Volkin, D.B.4
-
126
-
-
84878564386
-
Computational methods for high resolution prediction and refinement of protein structures
-
Friesner RA, Abel R, Goldfeld DA, et al. Computational methods for high resolution prediction and refinement of protein structures. Curr Opin Struct Biol 2013; 23(2):177-84
-
(2013)
Curr Opin Struct Biol
, vol.23
, Issue.2
, pp. 177-184
-
-
Friesner, R.A.1
Abel, R.2
Goldfeld, D.A.3
-
127
-
-
84877746282
-
Protein structure determination by magic-Angle spinning solid-state NMR, and insights into the formation, structure, and stability of amyloid fibrils
-
Comellas G, Rienstra CM. Protein structure determination by magic-Angle spinning solid-state NMR, and insights into the formation, structure, and stability of amyloid fibrils. Annu Rev Biophys 2013;42: 515-36
-
(2013)
Annu Rev Biophys
, vol.42
, pp. 515-536
-
-
Comellas, G.1
Rienstra, C.M.2
-
128
-
-
84884239080
-
Cryo-electron tomography: The challenge of doing structural biology in situ
-
Lucic V, Rigort A, Baumeister W. Cryo-electron tomography: The challenge of doing structural biology in situ. J Cell Biol 2013;202(3):407-19
-
(2013)
J Cell Biol
, vol.202
, Issue.3
, pp. 407-419
-
-
Lucic, V.1
Rigort, A.2
Baumeister, W.3
-
129
-
-
77951267552
-
Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products
-
Carpenter JF, Randolph TW, Jiskoot W, et al. Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products. J Pharm Sci 2010;99(5):2200-8
-
(2010)
J Pharm Sci
, vol.99
, Issue.5
, pp. 2200-2208
-
-
Carpenter, J.F.1
Randolph, T.W.2
Jiskoot, W.3
-
130
-
-
68949085124
-
Protein aggregation: Pathways, induction factors and analysis
-
Mahler HC, Friess W, Grauschopf U, Kiese S. Protein aggregation: Pathways, induction factors and analysis. J Pharm Sci 2009;98(9):2909-34
-
(2009)
J Pharm Sci
, vol.98
, Issue.9
, pp. 2909-2934
-
-
Mahler, H.C.1
Friess, W.2
Grauschopf, U.3
Kiese, S.4
-
131
-
-
36849049288
-
Development of a high throughput equilibrium solubility assay using miniaturized shake-flask method in early drug discovery
-
Zhou L, Yang L, Tilton S, Wang J. Development of a high throughput equilibrium solubility assay using miniaturized shake-flask method in early drug discovery. J Pharm Sci 2007;96(11): 3052-71
-
(2007)
J Pharm Sci
, vol.96
, Issue.11
, pp. 3052-3071
-
-
Zhou, L.1
Yang, L.2
Tilton, S.3
Wang, J.4
-
132
-
-
84876340793
-
How subvisible particles become invisible-relevance of the refractive index for protein particle analysis
-
Zolls S, Gregoritza M, Tantipolphan R, et al. How subvisible particles become invisible-relevance of the refractive index for protein particle analysis. J Pharm Sci 2013; 102(5):1434-46
-
(2013)
J Pharm Sci
, vol.102
, Issue.5
, pp. 1434-1446
-
-
Zolls, S.1
Gregoritza, M.2
Tantipolphan, R.3
-
133
-
-
84889088785
-
Pharmaceutical feasibility of sub-visible particle analysis in parenterals with reduced volume light obscuration methods
-
Pt B
-
Hawe A, Schaubhut F, Geidobler R, et al. Pharmaceutical feasibility of sub-visible particle analysis in parenterals with reduced volume light obscuration methods. Eur J Pharm Biopharm 2013;85(3 Pt B):1084-7
-
(2013)
Eur J Pharm Biopharm
, vol.85
, Issue.3
, pp. 1084-1087
-
-
Hawe, A.1
Schaubhut, F.2
Geidobler, R.3
-
134
-
-
69249215475
-
A critical review of analytical methods for subvisible and visible particles
-
Narhi LO, Jiang Y, Cao S, et al. A critical review of analytical methods for subvisible and visible particles. Curr Pharm Biotechnol 2009;10(4):373-81
-
(2009)
Curr Pharm Biotechnol
, vol.10
, Issue.4
, pp. 373-381
-
-
Narhi, L.O.1
Jiang, Y.2
Cao, S.3
-
135
-
-
84860784107
-
Issues and challenges of subvisible and submicron particulate analysis in protein solutions
-
Scherer TM, Leung S, Owyang L, Shire SJ. Issues and challenges of subvisible and submicron particulate analysis in protein solutions. Aaps J 2012;14(2):236-43
-
(2012)
Aaps J
, vol.14
, Issue.2
, pp. 236-243
-
-
Scherer, T.M.1
Leung, S.2
Owyang, L.3
Shire, S.J.4
-
136
-
-
84855872738
-
Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release
-
Jiskoot W, Randolph TW, Volkin DB, et al. Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release. J Pharm Sci 2012;101(3):946-54
-
(2012)
J Pharm Sci
, vol.101
, Issue.3
, pp. 946-954
-
-
Jiskoot, W.1
Randolph, T.W.2
Volkin, D.B.3
-
137
-
-
84892684084
-
Effect of solution properties on the counting and sizing of subvisible particle standards as measured by light obscuration and digital imaging methods
-
Werk T, Volkin DB, Mahler HC. Effect of solution properties on the counting and sizing of subvisible particle standards as measured by light obscuration and digital imaging methods. Eur J Pharm Sci 2014;53:95-108
-
(2014)
Eur J Pharm Sci
, vol.53
, pp. 95-108
-
-
Werk, T.1
Volkin, D.B.2
Mahler, H.C.3
|