Issues and challenges of subvisible and submicron particulate analysis in protein solutions

AAPS Journal

Volumn 14, Issue 2, 2012, Pages 236-243

  Scherer, Thomas M ^a   Leung, Stephenie ^a   Owyang, Laura ^a   Shire, Steven J ^a  

^a GENENTECH INC   (United States)

Author keywords

Light scattering methods for particle characterization; Particle analysis in high concentration protein solutions; Particle formation; Particle size and distribution analysis; Submicron particle characterization; Subvisible particle characterization

Indexed keywords

PROTEIN;

ARTICLE; CHEMICAL PARAMETERS; CONCENTRATION (PARAMETERS); DYNAMIC LIGHT SCATTERING; LIGHT SCATTERING; PARTICLE COUNT; PARTICLE SIZE; PARTICULATE MATTER;

IMMUNOGLOBULIN G; PARTICLE SIZE; PHARMACEUTICAL SOLUTIONS; PROTEINS; SCATTERING, SMALL ANGLE; X-RAY DIFFRACTION;

EID: 84860784107     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-012-9335-8     Document Type: Article

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