-
1
-
-
0037427444
-
Mitochondrial intermembrane proteins in cell death
-
van Gurp M, Festjens N, van Loo G, Saelens X, Vandenabeele P (2003) Mitochondrial intermembrane proteins in cell death. Biochem Biophys Res Commun 304(3):487-497
-
(2003)
Biochem Biophys Res Commun
, vol.304
, Issue.3
, pp. 487-497
-
-
Van Gurp, M.1
Festjens, N.2
Van Loo, G.3
Saelens, X.4
Vandenabeele, P.5
-
2
-
-
48249140223
-
Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells
-
Fandy TE, Shankar S, Srivastava RK (2008) Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells. Mol Cancer 7:60
-
(2008)
Mol Cancer
, vol.7
, pp. 60
-
-
Fandy, T.E.1
Shankar, S.2
Srivastava, R.K.3
-
3
-
-
70449107007
-
Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis
-
Autret A, Martin SJ (2009) Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis. Mol Cell 36(3):355-363
-
(2009)
Mol Cell
, vol.36
, Issue.3
, pp. 355-363
-
-
Autret, A.1
Martin, S.J.2
-
4
-
-
54349099181
-
Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells
-
Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S (2008) Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells. Free Radic Biol Med 45(10):1403-1412
-
(2008)
Free Radic Biol Med
, vol.45
, Issue.10
, pp. 1403-1412
-
-
Thayyullathil, F.1
Chathoth, S.2
Hago, A.3
Patel, M.4
Galadari, S.5
-
5
-
-
84863670779
-
Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits growth of human lung cancer A549 cells by arresting cell cycle and triggering apoptosis
-
Li L, Chen GG, Lu YN, Liu Y, Wu KF, Gong XL, Gou ZP, Li MY, Liang NC (2012) Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits growth of human lung cancer A549 cells by arresting cell cycle and triggering apoptosis. Chin J Cancer Res 24(2):109-115
-
(2012)
Chin J Cancer Res
, vol.24
, Issue.2
, pp. 109-115
-
-
Li, L.1
Chen, G.G.2
Lu, Y.N.3
Liu, Y.4
Wu, K.F.5
Gong, X.L.6
Gou, Z.P.7
Li, M.Y.8
Liang, N.C.9
-
6
-
-
84874429394
-
5-Benzylglycinyl-amiloride kills proliferating and nonproliferating malignant glioma cells through caspase-independent necroptosis mediated by apoptosis-inducing factor
-
Pasupuleti N, Leon L, Carraway KL 3rd, Gorin F (2013) 5-Benzylglycinyl-amiloride kills proliferating and nonproliferating malignant glioma cells through caspase-independent necroptosis mediated by apoptosis-inducing factor. J Pharmacol Exp Ther 344(3):600-615
-
(2013)
J Pharmacol Exp Ther
, vol.344
, Issue.3
, pp. 600-615
-
-
Pasupuleti, N.1
Leon, L.2
Carraway III, K.L.3
Gorin, F.4
-
7
-
-
84880482712
-
Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells
-
Seo KS, Kim H, Hong TH, Kim JS, Song KS, Yun EJ, Park JH, Jung YH, Park JI, Kweon GR, Yoon WH, Lim K, Hwang BD (2013) Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells. Biochem Biophys Res Commun 434(3):634-640
-
(2013)
Biochem Biophys Res Commun
, vol.434
, Issue.3
, pp. 634-640
-
-
Seo, K.S.1
Kim, H.2
Hong, T.H.3
Kim, J.S.4
Song, K.S.5
Yun, E.J.6
Park, J.H.7
Jung, Y.H.8
Park, J.I.9
Kweon, G.R.10
Yoon, W.H.11
Lim, K.12
Hwang, B.D.13
-
8
-
-
0038793948
-
Apoptosis and melanoma chemoresistance
-
Soengas MS, Lowe SW (2003) Apoptosis and melanoma chemoresistance. Oncogene 22(20):3138-3151
-
(2003)
Oncogene
, vol.22
, Issue.20
, pp. 3138-3151
-
-
Soengas, M.S.1
Lowe, S.W.2
-
9
-
-
0037069938
-
Down-regulation of caspase 3 in breast cancer: A possible mechanism for chemoresistance
-
Devarajan E, Sahin AA, Chen JS, Krishnamurthy RR, Aggarwal N, Brun AM, Sapino A, Zhang F, Sharma D, Yang XH, Tora AD, Mehta K (2002) Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance. Oncogene 21(57):8843-8851
-
(2002)
Oncogene
, vol.21
, Issue.57
, pp. 8843-8851
-
-
Devarajan, E.1
Sahin, A.A.2
Chen, J.S.3
Krishnamurthy, R.R.4
Aggarwal, N.5
Brun, A.M.6
Sapino, A.7
Zhang, F.8
Sharma, D.9
Yang, X.H.10
Tora, A.D.11
Mehta, K.12
-
11
-
-
21644466555
-
A new steroidal saponin from Dioscorea cayenensis
-
Tokyo
-
Sautour M, Mitaine-Offer AC, Miyamoto T, Dongmo A, Lacaille-Dubois MA (2004) A new steroidal saponin from Dioscorea cayenensis. Chem Pharm Bull (Tokyo) 52(11):1353-1355
-
(2004)
Chem Pharm Bull
, vol.52
, Issue.11
, pp. 1353-1355
-
-
Sautour, M.1
Mitaine-Offer, A.C.2
Miyamoto, T.3
Dongmo, A.4
Lacaille-Dubois, M.A.5
-
12
-
-
38049075602
-
Dioscin (saponin)-induced generation of reactive oxygen species through mitochondria dysfunction: A proteomic-based study
-
Wang Y, Che CM, Chiu JF, He QY (2007) Dioscin (saponin)-induced generation of reactive oxygen species through mitochondria dysfunction: a proteomic-based study. J Proteome Res 6(12):4703-4710
-
(2007)
J Proteome Res
, vol.6
, Issue.12
, pp. 4703-4710
-
-
Wang, Y.1
Che, C.M.2
Chiu, J.F.3
He, Q.Y.4
-
13
-
-
71749084455
-
Structural analogues of diosgenyl saponins: Synthesis and anticancer activity
-
Kaskiw MJ, Tassotto ML, Mok M, Tokar SL, Pycko R, Th'ng J, Jiang ZH (2009) Structural analogues of diosgenyl saponins: synthesis and anticancer activity. Bioorg Med Chem 17(22):7670-7679
-
(2009)
Bioorg Med Chem
, vol.17
, Issue.22
, pp. 7670-7679
-
-
Kaskiw, M.J.1
Tassotto, M.L.2
Mok, M.3
Tokar, S.L.4
Pycko, R.5
Th'Ng, J.6
Jiang, Z.H.7
-
14
-
-
79953027878
-
Application of proteomic and bioinformatic techniques for studying the hepatoprotective effect of dioscin against CCl-induced liver damage in mice
-
Lu B, Yin L, Xu L, Peng J (2011) Application of proteomic and bioinformatic techniques for studying the hepatoprotective effect of dioscin against CCl-induced liver damage in mice. Planta Med 77(5):407-415
-
(2011)
Planta Med
, vol.77
, Issue.5
, pp. 407-415
-
-
Lu, B.1
Yin, L.2
Xu, L.3
Peng, J.4
-
15
-
-
0036480566
-
Apoptosis induced by dioscin in Hela cells
-
Cai J, Liu M, Wang Z, Ju Y (2002) Apoptosis induced by dioscin in Hela cells. Biol Pharm Bull 25(2):193-196
-
(2002)
Biol Pharm Bull
, vol.25
, Issue.2
, pp. 193-196
-
-
Cai, J.1
Liu, M.2
Wang, Z.3
Ju, Y.4
-
16
-
-
81755162318
-
Paris chinensis dioscin induces G2/M cell cycle arrest and apoptosis in human gastric cancer SGC-7901 cells
-
Gao LL, Li FR, Jiao P, Yang MF, Zhou XJ, Si YH, Jiang WJ, Zheng TT (2011) Paris chinensis dioscin induces G2/M cell cycle arrest and apoptosis in human gastric cancer SGC-7901 cells. World J Gastroenterol 17(39):4389-4395
-
(2011)
World J Gastroenterol
, vol.17
, Issue.39
, pp. 4389-4395
-
-
Gao, L.L.1
Li, F.R.2
Jiao, P.3
Yang, M.F.4
Zhou, X.J.5
Si, Y.H.6
Jiang, W.J.7
Zheng, T.T.8
-
17
-
-
0035112982
-
Effects of two saponins extracted from the Polygonatum zanlanscianense pamp on the human leukemia (HL-60) cells
-
Wang Z, Zhou J, Ju Y, Zhang H, Liu M, Li X (2001) Effects of two saponins extracted from the Polygonatum zanlanscianense pamp on the human leukemia (HL-60) cells. Biol Pharm Bull 24(2):159-162
-
(2001)
Biol Pharm Bull
, vol.24
, Issue.2
, pp. 159-162
-
-
Wang, Z.1
Zhou, J.2
Ju, Y.3
Zhang, H.4
Liu, M.5
Li, X.6
-
18
-
-
84881237192
-
Dioscin, a natural steroid saponin, induces apoptosis and DNA damage through reactive oxygen species: A potential new drug for treatment of glioblastoma multiforme
-
Lv L, Zheng L, Dong D, Xu L, Yin L, Xu Y, Qi Y, Han X, Peng J (2013) Dioscin, a natural steroid saponin, induces apoptosis and DNA damage through reactive oxygen species: a potential new drug for treatment of glioblastoma multiforme. Food Chem Toxicol 59:657-669
-
(2013)
Food Chem Toxicol
, vol.59
, pp. 657-669
-
-
Lv, L.1
Zheng, L.2
Dong, D.3
Xu, L.4
Yin, L.5
Xu, Y.6
Qi, Y.7
Han, X.8
Peng, J.9
-
19
-
-
84878237899
-
Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition
-
Wang L, Meng Q, Wang C, Liu Q, Peng J, Huo X, Sun H, Ma X, Liu K (2013) Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition. J Nat Prod 76(5):909-914
-
(2013)
J Nat Prod
, vol.76
, Issue.5
, pp. 909-914
-
-
Wang, L.1
Meng, Q.2
Wang, C.3
Liu, Q.4
Peng, J.5
Huo, X.6
Sun, H.7
Ma, X.8
Liu, K.9
-
20
-
-
84877887193
-
FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells
-
Ren SX, Shen J, Cheng AS, Lu L, Chan RL, Li ZJ, Wang XJ, Wong CC, Zhang L, Ng SS, Chan FL, Chan FK, Yu J, Sung JJ, Wu WK, Cho CH (2013) FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. PLoS ONE 8(5):e63641
-
(2013)
PLoS ONE
, vol.8
, Issue.5
-
-
Ren, S.X.1
Shen, J.2
Cheng, A.S.3
Lu, L.4
Chan, R.L.5
Li, Z.J.6
Wang, X.J.7
Wong, C.C.8
Zhang, L.9
Ng, S.S.10
Chan, F.L.11
Chan, F.K.12
Yu, J.13
Sung, J.J.14
Wu, W.K.15
Cho, C.H.16
-
21
-
-
67349150698
-
Targeting apoptosis as an approach for gastrointestinal cancer therapy
-
Qiao L, Wong BC (2009) Targeting apoptosis as an approach for gastrointestinal cancer therapy. Drug Resist Updat 12(3):55-64
-
(2009)
Drug Resist Updat
, vol.12
, Issue.3
, pp. 55-64
-
-
Qiao, L.1
Wong, B.C.2
-
22
-
-
79551604904
-
Reversal effect of Dioscin on multidrug resistance in human hepatoma HepG2/adriamycin cells
-
Sun BT, Zheng LH, Bao YL, Yu CL, Wu Y, Meng XY, Li YX (2011) Reversal effect of Dioscin on multidrug resistance in human hepatoma HepG2/adriamycin cells. Eur J Pharmacol 654(2):129-134
-
(2011)
Eur J Pharmacol
, vol.654
, Issue.2
, pp. 129-134
-
-
Sun, B.T.1
Zheng, L.H.2
Bao, Y.L.3
Yu, C.L.4
Wu, Y.5
Meng, X.Y.6
Li, Y.X.7
-
23
-
-
84879503246
-
Cytotoxicity of dioscin in human gastric carcinoma cells through death receptor and mitochondrial pathways
-
Hu M, Xu L, Yin L, Qi Y, Li H, Xu Y, Han X, Peng J, Wan X (2013) Cytotoxicity of dioscin in human gastric carcinoma cells through death receptor and mitochondrial pathways. J Appl Toxicol 33(8):712-722
-
(2013)
J Appl Toxicol
, vol.33
, Issue.8
, pp. 712-722
-
-
Hu, M.1
Xu, L.2
Yin, L.3
Qi, Y.4
Li, H.5
Xu, Y.6
Han, X.7
Peng, J.8
Wan, X.9
-
24
-
-
12244268624
-
Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death?
-
Candé C, Cecconi F, Dessen P, Kroemer G (2002) Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci 115(Pt 24):4727-4734
-
(2002)
J Cell Sci
, vol.115
, Issue.PART 24
, pp. 4727-4734
-
-
Candé, C.1
Cecconi, F.2
Dessen, P.3
Kroemer, G.4
-
25
-
-
77951923949
-
Mitochondrial control of caspase-dependent and -independent cell death
-
Pradelli LA, Bénéteau M, Ricci JE (2010) Mitochondrial control of caspase-dependent and -independent cell death. Cell Mol Life Sci 67(10):1589-1597
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.10
, pp. 1589-1597
-
-
Pradelli, L.A.1
Bénéteau, M.2
Ricci, J.E.3
-
26
-
-
10844264632
-
Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: Reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria
-
Kang YH, Yi MJ, Kim MJ, Park MT, Bae S, Kang CM, Cho CK, Park IC, Park MJ, Rhee CH, Hong SI, Chung HY, Lee YS, Lee SJ (2004) Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res 64(24):8960-8967
-
(2004)
Cancer Res
, vol.64
, Issue.24
, pp. 8960-8967
-
-
Kang, Y.H.1
Yi, M.J.2
Kim, M.J.3
Park, M.T.4
Bae, S.5
Kang, C.M.6
Cho, C.K.7
Park, I.C.8
Park, M.J.9
Rhee, C.H.10
Hong, S.I.11
Chung, H.Y.12
Lee, Y.S.13
Lee, S.J.14
-
27
-
-
84860521181
-
Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor
-
Wang L, Liu L, Shi Y, Cao H, Chaturvedi R, Calcutt MW, Hu T, Ren X, Wilson KT, Polk DB, Yan F (2012) Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. PLoS ONE 7(5):e36418
-
(2012)
PLoS ONE
, vol.7
, Issue.5
-
-
Wang, L.1
Liu, L.2
Shi, Y.3
Cao, H.4
Chaturvedi, R.5
Calcutt, M.W.6
Hu, T.7
Ren, X.8
Wilson, K.T.9
Polk, D.B.10
Yan, F.11
-
28
-
-
84863131822
-
Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by down-regulation of peroxiredoxins
-
Wang Z, Cheng Y, Wang N, Wang DM, Li YW, Han F, Shen JG, de Yang P, Guan XY, Chen JP (2012) Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by down-regulation of peroxiredoxins. Cancer Biol Ther 13(3):138-147
-
(2012)
Cancer Biol Ther
, vol.13
, Issue.3
, pp. 138-147
-
-
Wang, Z.1
Cheng, Y.2
Wang, N.3
Wang, D.M.4
Li, Y.W.5
Han, F.6
Shen, J.G.7
De Yang, P.8
Guan, X.Y.9
Chen, J.P.10
-
29
-
-
53949096956
-
Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma
-
Li L, Gao Y, Zhang L, Zeng J, He D, Sun Y (2008) Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma. Cancer Lett 272(1):61-69
-
(2008)
Cancer Lett
, vol.272
, Issue.1
, pp. 61-69
-
-
Li, L.1
Gao, Y.2
Zhang, L.3
Zeng, J.4
He, D.5
Sun, Y.6
-
30
-
-
79960206850
-
Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation
-
Spagnuolo C, Cerella C, Russo M, Chateauvieux S, Diederich M, Russo GL (2011) Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation. Br J Cancer 105(2):221-230
-
(2011)
Br J Cancer
, vol.105
, Issue.2
, pp. 221-230
-
-
Spagnuolo, C.1
Cerella, C.2
Russo, M.3
Chateauvieux, S.4
Diederich, M.5
Russo, G.L.6
-
31
-
-
80054055472
-
25-OCH3-PPD induces the apoptosis of activated t-HSC/Cl-6 cells via c-FLIP-mediated NF-κB activation
-
Wu YL, Wan Y, Jin XJ, OuYang BQ, Bai T, Zhao YQ, Nan JX (2011) 25-OCH3-PPD induces the apoptosis of activated t-HSC/Cl-6 cells via c-FLIP-mediated NF-κB activation. Chem Biol Interact 194(2-3):106-112
-
(2011)
Chem Biol Interact
, vol.194
, Issue.2-3
, pp. 106-112
-
-
Wu, Y.L.1
Wan, Y.2
Jin, X.J.3
OuYang, B.Q.4
Bai, T.5
Zhao, Y.Q.6
Nan, J.X.7
-
32
-
-
84861595113
-
Oleifolioside A mediates caspase-independent human cervical carcinoma HeLa cell apoptosis involving nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG
-
Yu HY, Jin CY, Kim KS, Lee YC, Park SH, Kim GY, Kim WJ, Moon HI, Choi YH, Lee JH (2012) Oleifolioside A mediates caspase-independent human cervical carcinoma HeLa cell apoptosis involving nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG. J Agric Food Chem 60(21):5400-5406
-
(2012)
J Agric Food Chem
, vol.60
, Issue.21
, pp. 5400-5406
-
-
Yu, H.Y.1
Jin, C.Y.2
Kim, K.S.3
Lee, Y.C.4
Park, S.H.5
Kim, G.Y.6
Kim, W.J.7
Moon, H.I.8
Choi, Y.H.9
Lee, J.H.10
-
33
-
-
84879835143
-
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway
-
Wei Y, Xu Y, Han X, Qi Y, Xu L, Xu Y, Yin L, Sun H, Liu K, Peng J (2013) Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway. Food Chem Toxicol 59:118-128
-
(2013)
Food Chem Toxicol
, vol.59
, pp. 118-128
-
-
Wei, Y.1
Xu, Y.2
Han, X.3
Qi, Y.4
Xu, L.5
Xu, Y.6
Yin, L.7
Sun, H.8
Liu, K.9
Peng, J.10
-
34
-
-
84866445045
-
Dioscin sensitizes cells to TRAIL-induced apoptosis through downregulation of c-FLIP and Bcl-2
-
Kim YS, Kim EA, Park KG, Lee SJ, Kim MS, Sohn HY, Lee TJ (2012) Dioscin sensitizes cells to TRAIL-induced apoptosis through downregulation of c-FLIP and Bcl-2. Oncol Rep 28(5):1910-1916
-
(2012)
Oncol Rep
, vol.28
, Issue.5
, pp. 1910-1916
-
-
Kim, Y.S.1
Kim, E.A.2
Park, K.G.3
Lee, S.J.4
Kim, M.S.5
Sohn, H.Y.6
Lee, T.J.7
-
35
-
-
84870230222
-
Autophagy inhibition enhances apoptosis induced by dioscin in huh7 cells
-
Hsieh MJ, Yang SF, Hsieh YS, Chen TY, Chiou HL (2012) Autophagy inhibition enhances apoptosis induced by dioscin in huh7 cells. Evid Based Complement Alternat Med 2012:134512
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 134512
-
-
Hsieh, M.J.1
Yang, S.F.2
Hsieh, Y.S.3
Chen, T.Y.4
Chiou, H.L.5
-
36
-
-
84885958665
-
Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines
-
Hsieh MJ, Tsai TL, Hsieh YS, Wang CJ, Chiou HL (2013) Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines. Arch Toxicol 87(11):1927-1937
-
(2013)
Arch Toxicol
, vol.87
, Issue.11
, pp. 1927-1937
-
-
Hsieh, M.J.1
Tsai, T.L.2
Hsieh, Y.S.3
Wang, C.J.4
Chiou, H.L.5
|