Dioscin sensitizes cells to TRAIL-induced apoptosis through downregulation of c-FLIP and Bcl-2

Oncology Reports

Volumn 28, Issue 5, 2012, Pages 1910-1916

  Kim, Yong Sik ^c   Kim, Eun Ae ^a   Park, Kyu Gun ^a   Lee, Sung Jun ^a   Kim, Mi Sun ^c   Sohn, Ho Yong ^b   Lee, Tae Jin ^a  

^a Yeungnam University College of Medicine   (South Korea)

^b Andong National University   (South Korea)

^c Soonchunhyang University   (South Korea)

Author keywords

Bcl 2; c FLIP; Dioscin; Tumor necrosis factor related apoptosis inducing ligand

Indexed keywords

ANTINEOPLASTIC AGENT; DIOSCIN; FLICE INHIBITORY PROTEIN; PROTEIN BCL 2; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG SAFETY; HUMAN; HUMAN CELL; KIDNEY CANCER; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; SENSITIZATION; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CARCINOMA, RENAL CELL; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 3; DIOSGENIN; DOWN-REGULATION; HUMANS; KIDNEY NEOPLASMS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84866445045     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1962     Document Type: Article

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