메뉴 건너뛰기




Volumn 7, Issue 5, 2014, Pages 1481-1494

Intertissue control of the nucleolus via a myokine-dependent longevity pathway

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE P38; MUSCLE PROTEIN; MYOGLIANIN; MYOKINE; MYOSTATIN; PROTEIN GDF11; RIBOSOME RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MNT; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE 14; REGULATOR PROTEIN; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; DROSOPHILA PROTEIN; MYOGLIANIN PROTEIN, DROSOPHILA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84902345421     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.05.001     Document Type: Article
Times cited : (92)

References (74)
  • 2
    • 79959675995 scopus 로고    scopus 로고
    • Glia instruct developmental neuronal remodeling through TGF-β signaling
    • Awasaki T., Huang Y., O'Connor M.B., Lee T. Glia instruct developmental neuronal remodeling through TGF-β signaling. Nat. Neurosci. 2011, 14:821-823.
    • (2011) Nat. Neurosci. , vol.14 , pp. 821-823
    • Awasaki, T.1    Huang, Y.2    O'Connor, M.B.3    Lee, T.4
  • 3
    • 84888225099 scopus 로고    scopus 로고
    • Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila
    • Bai H., Kang P., Hernandez A.M., Tatar M. Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila. PLoS Genet. 2013, 9:e1003941.
    • (2013) PLoS Genet. , vol.9
    • Bai, H.1    Kang, P.2    Hernandez, A.M.3    Tatar, M.4
  • 6
    • 66149094692 scopus 로고    scopus 로고
    • Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila
    • Demontis F., Perrimon N. Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Development 2009, 136:983-993.
    • (2009) Development , vol.136 , pp. 983-993
    • Demontis, F.1    Perrimon, N.2
  • 7
    • 78650918920 scopus 로고    scopus 로고
    • FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
    • Demontis F., Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 2010, 143:813-825.
    • (2010) Cell , vol.143 , pp. 813-825
    • Demontis, F.1    Perrimon, N.2
  • 8
    • 84888136343 scopus 로고    scopus 로고
    • The influence of skeletal muscle on systemic aging and lifespan
    • Demontis F., Piccirillo R., Goldberg A.L., Perrimon N. The influence of skeletal muscle on systemic aging and lifespan. Aging Cell 2013, 12:943-949.
    • (2013) Aging Cell , vol.12 , pp. 943-949
    • Demontis, F.1    Piccirillo, R.2    Goldberg, A.L.3    Perrimon, N.4
  • 9
    • 84888363022 scopus 로고    scopus 로고
    • Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models
    • Demontis F., Piccirillo R., Goldberg A.L., Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Dis. Model. Mech. 2013, 6:1339-1352.
    • (2013) Dis. Model. Mech. , vol.6 , pp. 1339-1352
    • Demontis, F.1    Piccirillo, R.2    Goldberg, A.L.3    Perrimon, N.4
  • 10
    • 5344226944 scopus 로고    scopus 로고
    • Cell and molecular biology of nucleolar assembly and disassembly
    • Dimario P.J. Cell and molecular biology of nucleolar assembly and disassembly. Int. Rev. Cytol. 2004, 239:99-178.
    • (2004) Int. Rev. Cytol. , vol.239 , pp. 99-178
    • Dimario, P.J.1
  • 11
    • 66149097065 scopus 로고    scopus 로고
    • Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling
    • Drummond M.J., Dreyer H.C., Fry C.S., Glynn E.L., Rasmussen B.B. Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling. J.Appl. Physiol. 2009, 106:1374-1384.
    • (2009) J.Appl. Physiol. , vol.106 , pp. 1374-1384
    • Drummond, M.J.1    Dreyer, H.C.2    Fry, C.S.3    Glynn, E.L.4    Rasmussen, B.B.5
  • 12
    • 78650944949 scopus 로고    scopus 로고
    • The cell-non-autonomous nature of electron transport chain-mediated longevity
    • Durieux J., Wolff S., Dillin A. The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 2011, 144:79-91.
    • (2011) Cell , vol.144 , pp. 79-91
    • Durieux, J.1    Wolff, S.2    Dillin, A.3
  • 13
    • 78049438081 scopus 로고    scopus 로고
    • The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles
    • Duteil D., Chambon C., Ali F., Malivindi R., Zoll J., Kato S., Geny B., Chambon P., Metzger D. The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles. Cell Metab. 2010, 12:496-508.
    • (2010) Cell Metab. , vol.12 , pp. 496-508
    • Duteil, D.1    Chambon, C.2    Ali, F.3    Malivindi, R.4    Zoll, J.5    Kato, S.6    Geny, B.7    Chambon, P.8    Metzger, D.9
  • 14
    • 33750345334 scopus 로고    scopus 로고
    • Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects
    • Feldman B.J., Streeper R.S., Farese R.V., Yamamoto K.R. Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Proc. Natl. Acad. Sci. USA 2006, 103:15675-15680.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15675-15680
    • Feldman, B.J.1    Streeper, R.S.2    Farese, R.V.3    Yamamoto, K.R.4
  • 16
    • 78650455618 scopus 로고    scopus 로고
    • Hindlimb skeletal muscle function in myostatin-deficient mice
    • Gentry B.A., Ferreira J.A., Phillips C.L., Brown M. Hindlimb skeletal muscle function in myostatin-deficient mice. Muscle Nerve 2011, 43:49-57.
    • (2011) Muscle Nerve , vol.43 , pp. 49-57
    • Gentry, B.A.1    Ferreira, J.A.2    Phillips, C.L.3    Brown, M.4
  • 18
    • 37249034796 scopus 로고    scopus 로고
    • Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway
    • Grewal S.S., Evans J.R., Edgar B.A. Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway. J.Cell Biol. 2007, 179:1105-1113.
    • (2007) J.Cell Biol. , vol.179 , pp. 1105-1113
    • Grewal, S.S.1    Evans, J.R.2    Edgar, B.A.3
  • 19
    • 0030867827 scopus 로고    scopus 로고
    • Link between aging and the nucleolus
    • Guarente L. Link between aging and the nucleolus. Genes Dev. 1997, 11:2449-2455.
    • (1997) Genes Dev. , vol.11 , pp. 2449-2455
    • Guarente, L.1
  • 20
    • 78649350746 scopus 로고    scopus 로고
    • The aging stress response
    • Haigis M.C., Yankner B.A. The aging stress response. Mol. Cell 2010, 40:333-344.
    • (2010) Mol. Cell , vol.40 , pp. 333-344
    • Haigis, M.C.1    Yankner, B.A.2
  • 22
    • 33846423520 scopus 로고    scopus 로고
    • Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
    • Hansen M., Taubert S., Crawford D., Libina N., Lee S.J., Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 2007, 6:95-110.
    • (2007) Aging Cell , vol.6 , pp. 95-110
    • Hansen, M.1    Taubert, S.2    Crawford, D.3    Libina, N.4    Lee, S.J.5    Kenyon, C.6
  • 24
    • 84888356912 scopus 로고    scopus 로고
    • Whole-mount immunostaining of Drosophila skeletal muscle
    • Hunt L.C., Demontis F. Whole-mount immunostaining of Drosophila skeletal muscle. Nat. Protoc. 2013, 8:2496-2501.
    • (2013) Nat. Protoc. , vol.8 , pp. 2496-2501
    • Hunt, L.C.1    Demontis, F.2
  • 25
    • 33748136848 scopus 로고    scopus 로고
    • The MAX-interacting transcription factor network
    • Hurlin P.J., Huang J. The MAX-interacting transcription factor network. Semin. Cancer Biol. 2006, 16:265-274.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 265-274
    • Hurlin, P.J.1    Huang, J.2
  • 26
    • 2942563805 scopus 로고    scopus 로고
    • Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
    • Hwangbo D.S., Gershman B., Tu M.P., Palmer M., Tatar M. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 2004, 429:562-566.
    • (2004) Nature , vol.429 , pp. 562-566
    • Hwangbo, D.S.1    Gershman, B.2    Tu, M.P.3    Palmer, M.4    Tatar, M.5
  • 27
    • 84859366546 scopus 로고    scopus 로고
    • MTOR signaling regulates the processing of pre-rRNA in human cells
    • Iadevaia V., Zhang Z., Jan E., Proud C.G. mTOR signaling regulates the processing of pre-rRNA in human cells. Nucleic Acids Res. 2012, 40:2527-2539.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 2527-2539
    • Iadevaia, V.1    Zhang, Z.2    Jan, E.3    Proud, C.G.4
  • 28
    • 79958181684 scopus 로고    scopus 로고
    • Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage
    • Karpac J., Younger A., Jasper H. Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage. Dev. Cell 2011, 20:841-854.
    • (2011) Dev. Cell , vol.20 , pp. 841-854
    • Karpac, J.1    Younger, A.2    Jasper, H.3
  • 29
    • 84863514544 scopus 로고    scopus 로고
    • Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster
    • Katewa S.D., Demontis F., Kolipinski M., Hubbard A., Gill M.S., Perrimon N., Melov S., Kapahi P. Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metab. 2012, 16:97-103.
    • (2012) Cell Metab. , vol.16 , pp. 97-103
    • Katewa, S.D.1    Demontis, F.2    Kolipinski, M.3    Hubbard, A.4    Gill, M.S.5    Perrimon, N.6    Melov, S.7    Kapahi, P.8
  • 30
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • Kenyon C.J. The genetics of ageing. Nature 2010, 464:504-512.
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 31
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee S.J. Regulation of muscle mass by myostatin. Annu. Rev. Cell Dev. Biol. 2004, 20:61-86.
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 32
    • 50349094996 scopus 로고    scopus 로고
    • Myostatin directly regulates skeletal muscle fibrosis
    • Li Z.B., Kollias H.D., Wagner K.R. Myostatin directly regulates skeletal muscle fibrosis. J.Biol. Chem. 2008, 283:19371-19378.
    • (2008) J.Biol. Chem. , vol.283 , pp. 19371-19378
    • Li, Z.B.1    Kollias, H.D.2    Wagner, K.R.3
  • 33
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C.elegans DAF-16 in the regulation of lifespan
    • Libina N., Berman J.R., Kenyon C. Tissue-specific activities of C.elegans DAF-16 in the regulation of lifespan. Cell 2003, 115:489-502.
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 34
    • 0032788804 scopus 로고    scopus 로고
    • Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-beta superfamily
    • Lo P.C., Frasch M. Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-beta superfamily. Mech. Dev. 1999, 86:171-175.
    • (1999) Mech. Dev. , vol.86 , pp. 171-175
    • Lo, P.C.1    Frasch, M.2
  • 37
    • 17444430871 scopus 로고    scopus 로고
    • The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis
    • Mayer C., Bierhoff H., Grummt I. The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev. 2005, 19:933-941.
    • (2005) Genes Dev. , vol.19 , pp. 933-941
    • Mayer, C.1    Bierhoff, H.2    Grummt, I.3
  • 39
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron A.C., Lawler A.M., Lee S.J. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 1997, 387:83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 42
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-beta signals
    • Moustakas A., Heldin C.H. Non-Smad TGF-beta signals. J.Cell Sci. 2005, 118:3573-3584.
    • (2005) J.Cell Sci. , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 43
  • 46
    • 84886786722 scopus 로고    scopus 로고
    • Muscle mitohormesis promotes longevity via systemic repression of insulin signaling
    • Owusu-Ansah E., Song W., Perrimon N. Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Cell 2013, 155:699-712.
    • (2013) Cell , vol.155 , pp. 699-712
    • Owusu-Ansah, E.1    Song, W.2    Perrimon, N.3
  • 48
    • 68149169938 scopus 로고    scopus 로고
    • Signals of youth: endocrine regulation of aging in Caenorhabditis elegans
    • Panowski S.H., Dillin A. Signals of youth: endocrine regulation of aging in Caenorhabditis elegans. Trends Endocrinol. Metab. 2009, 20:259-264.
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 259-264
    • Panowski, S.H.1    Dillin, A.2
  • 49
    • 84864283300 scopus 로고    scopus 로고
    • Muscles, exercise and obesity: skeletal muscle as a secretory organ
    • Pedersen B.K., Febbraio M.A. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat. Rev. Endocrinol. 2012, 8:457-465.
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 457-465
    • Pedersen, B.K.1    Febbraio, M.A.2
  • 50
    • 9644281085 scopus 로고    scopus 로고
    • Regulation of GDF-8 signaling by the p38 MAPK
    • Philip B., Lu Z., Gao Y. Regulation of GDF-8 signaling by the p38 MAPK. Cell. Signal. 2005, 17:365-375.
    • (2005) Cell. Signal. , vol.17 , pp. 365-375
    • Philip, B.1    Lu, Z.2    Gao, Y.3
  • 51
    • 84892679130 scopus 로고    scopus 로고
    • Mechanisms of muscle growth and atrophy in mammals and Drosophila
    • Piccirillo R., Demontis F., Perrimon N., Goldberg A.L. Mechanisms of muscle growth and atrophy in mammals and Drosophila. Dev. Dyn. 2014, 243:201-215.
    • (2014) Dev. Dyn. , vol.243 , pp. 201-215
    • Piccirillo, R.1    Demontis, F.2    Perrimon, N.3    Goldberg, A.L.4
  • 54
    • 47749084250 scopus 로고    scopus 로고
    • Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed
    • Rhodenizer D., Martin I., Bhandari P., Pletcher S.D., Grotewiel M. Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed. Exp. Gerontol. 2008, 43:739-748.
    • (2008) Exp. Gerontol. , vol.43 , pp. 739-748
    • Rhodenizer, D.1    Martin, I.2    Bhandari, P.3    Pletcher, S.D.4    Grotewiel, M.5
  • 58
    • 84883476818 scopus 로고    scopus 로고
    • Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
    • Satoh A., Brace C.S., Rensing N., Cliften P., Wozniak D.F., Herzog E.D., Yamada K.A., Imai S. Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab. 2013, 18:416-430.
    • (2013) Cell Metab. , vol.18 , pp. 416-430
    • Satoh, A.1    Brace, C.S.2    Rensing, N.3    Cliften, P.4    Wozniak, D.F.5    Herzog, E.D.6    Yamada, K.A.7    Imai, S.8
  • 59
    • 0030273379 scopus 로고    scopus 로고
    • Geneticdissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth
    • Schuster C.M., Davis G.W., Fetter R.D., Goodman C.S. Geneticdissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth. Neuron 1996, 17:641-654.
    • (1996) Neuron , vol.17 , pp. 641-654
    • Schuster, C.M.1    Davis, G.W.2    Fetter, R.D.3    Goodman, C.S.4
  • 60
    • 33846127120 scopus 로고    scopus 로고
    • The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance
    • Serpe M., O'Connor M.B. The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance. Development 2006, 133:4969-4979.
    • (2006) Development , vol.133 , pp. 4969-4979
    • Serpe, M.1    O'Connor, M.B.2
  • 61
    • 56749170664 scopus 로고    scopus 로고
    • Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators
    • Souza T.A., Chen X., Guo Y., Sava P., Zhang J., Hill J.J., Yaworsky P.J., Qiu Y. Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators. Mol. Endocrinol. 2008, 22:2689-2702.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 2689-2702
    • Souza, T.A.1    Chen, X.2    Guo, Y.3    Sava, P.4    Zhang, J.5    Hill, J.J.6    Yaworsky, P.J.7    Qiu, Y.8
  • 63
    • 77956533094 scopus 로고    scopus 로고
    • Indicators of "healthy aging" in older women (65-69 years of age). A data-mining approach based on prediction of long-term survival
    • Study Of Osteoporotic Fractures Research Group
    • Swindell W.R., Ensrud K.E., Cawthon P.M., Cauley J.A., Cummings S.R., Miller R.A. Indicators of "healthy aging" in older women (65-69 years of age). A data-mining approach based on prediction of long-term survival. BMC Geriatr. 2010, 10:55. Study Of Osteoporotic Fractures Research Group.
    • (2010) BMC Geriatr. , vol.10 , pp. 55
    • Swindell, W.R.1    Ensrud, K.E.2    Cawthon, P.M.3    Cauley, J.A.4    Cummings, S.R.5    Miller, R.A.6
  • 64
    • 36549020042 scopus 로고    scopus 로고
    • Protein synthesis is a novel determinant of aging in Caenorhabditis elegans
    • Syntichaki P., Troulinaki K., Tavernarakis N. Protein synthesis is a novel determinant of aging in Caenorhabditis elegans. Ann. N Y Acad. Sci. 2007, 1119:289-295.
    • (2007) Ann. N Y Acad. Sci. , vol.1119 , pp. 289-295
    • Syntichaki, P.1    Troulinaki, K.2    Tavernarakis, N.3
  • 65
    • 34547097247 scopus 로고    scopus 로고
    • Brain IRS2 signaling coordinates life span and nutrient homeostasis
    • Taguchi A., Wartschow L.M., White M.F. Brain IRS2 signaling coordinates life span and nutrient homeostasis. Science 2007, 317:369-372.
    • (2007) Science , vol.317 , pp. 369-372
    • Taguchi, A.1    Wartschow, L.M.2    White, M.F.3
  • 66
    • 84878873702 scopus 로고    scopus 로고
    • Regulation of organismal proteostasis by transcellular chaperone signaling
    • van Oosten-Hawle P., Porter R.S., Morimoto R.I. Regulation of organismal proteostasis by transcellular chaperone signaling. Cell 2013, 153:1366-1378.
    • (2013) Cell , vol.153 , pp. 1366-1378
    • van Oosten-Hawle, P.1    Porter, R.S.2    Morimoto, R.I.3
  • 68
    • 17044408768 scopus 로고    scopus 로고
    • JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
    • Wang M.C., Bohmann D., Jasper H. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 2005, 121:115-125.
    • (2005) Cell , vol.121 , pp. 115-125
    • Wang, M.C.1    Bohmann, D.2    Jasper, H.3
  • 69
    • 55849101681 scopus 로고    scopus 로고
    • Fat metabolism links germline stem cells and longevity in C. elegans
    • Wang M.C., O'Rourke E.J., Ruvkun G. Fat metabolism links germline stem cells and longevity in C. elegans. Science 2008, 322:957-960.
    • (2008) Science , vol.322 , pp. 957-960
    • Wang, M.C.1    O'Rourke, E.J.2    Ruvkun, G.3
  • 71
    • 33750093325 scopus 로고    scopus 로고
    • The underappreciated role of muscle in health and disease
    • Wolfe R.R. The underappreciated role of muscle in health and disease. Am. J. Clin. Nutr. 2006, 84:475-482.
    • (2006) Am. J. Clin. Nutr. , vol.84 , pp. 475-482
    • Wolfe, R.R.1
  • 72
    • 79957992660 scopus 로고    scopus 로고
    • A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans
    • Youngman M.J., Rogers Z.N., Kim D.H. A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. PLoS Genet. 2011, 7:e1002082.
    • (2011) PLoS Genet. , vol.7
    • Youngman, M.J.1    Rogers, Z.N.2    Kim, D.H.3
  • 73
    • 0034312315 scopus 로고    scopus 로고
    • Regulation of cellular growth by the Drosophila target of rapamycin dTOR
    • Zhang H., Stallock J.P., Ng J.C., Reinhard C., Neufeld T.P. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 2000, 14:2712-2724.
    • (2000) Genes Dev. , vol.14 , pp. 2712-2724
    • Zhang, H.1    Stallock, J.P.2    Ng, J.C.3    Reinhard, C.4    Neufeld, T.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.