Mechanisms of innate lymphoid cell and natural killer t cell activation during mucosal inflammation

Journal of Immunology Research

Volumn 2014, Issue , 2014, Pages

  Nau, David ^a   Altmayer, Nora ^a   Mattner, Jochen ^a,b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; CHEMOKINE RECEPTOR CCR4; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 25; INTERLEUKIN 33; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ASTHMA; CELL INTERACTION; CELL LINEAGE; CELL MATURATION; COLITIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; HUMAN; IMMUNOMODULATION; INFLAMMATION; INNATE LYMPHOID CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE SUBPOPULATION; LYMPHOID CELL; NATURAL KILLER T CELL; NONHUMAN; REVIEW; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; CELL COMMUNICATION; CELL DIFFERENTIATION; CYTOLOGY; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MUCOSA; MUCOSAL IMMUNITY; PATHOLOGY;

ANIMALS; ASTHMA; CELL COMMUNICATION; CELL DIFFERENTIATION; COLITIS; HUMANS; IMMUNITY, INNATE; IMMUNITY, MUCOSAL; INFLAMMATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MUCOUS MEMBRANE; NATURAL KILLER T-CELLS;

EID: 84902197637     PISSN: 23148861     EISSN: 23147156     Source Type: Journal    
DOI: 10.1155/2014/546596     Document Type: Review

References (111)

1. Wershil B. K., Furuta G. T., 4. Gastrointestinal mucosal immunity. Journal of Allergy and Clinical Immunology 2008 121 2 supplement 2 S380 S383 2-s2.0-38649137730 10.1016/j.jaci.2007.10.023 (Pubitemid 351172428)
2. Turner J. R., Intestinal mucosal barrier function in health and disease. Nature Reviews Immunology 2009 9 11 799 809 2-s2.0-70350509805 10.1038/nri2653
3. Mayer A. K., Dalpke A. H., Regulation of local immunity by airway epithelial cells. Archivum Immunologiae et Therapiae Experimentalis 2007 55 6 353 362 2-s2.0-38349099614 10.1007/s00005-007-0041-7
4. Sansonetti P. J., To be or not to be a pathogen: that is the mucosally relevant question. Mucosal Immunology 2011 4 1 8 14 2-s2.0-78650843522 10.1038/mi.2010.77
5. Steele L., Mayer L., Berin M. C., Mucosal immunology of tolerance and allergy in the gastrointestinal tract. Immunologic Research 2012 54 1-3 75 82 10.1007/s12026-012-8308-4
6. Kayama H., Takeda K., Regulation of intestinal homeostasis by innate and adaptive immunity. International Immunology 2012 24 11 673 680 10.1093/intimm/dxs094
7. McGhee J. R., Fujihashi K., Inside the mucosal immune system. PLoS Biology 2012 10 9 e1001397 10.1371/journal.pbio.1001397
8. Aparicio-Domingo P., Cupedo T., Ror γ t+ innate lymphoid cells in intestinal homeostasis and immunity. Journal of Innate Immunity 2011 3 6 577 584 2-s2.0-80054900196 10.1159/000330668
9. di Santo J. P., Vosshenrich C. A. J., Satoh-Takayama N., A "natural" way to provide innate mucosal immunity. Current Opinion in Immunology 2010 22 4 435 441 2-s2.0-77955653587 10.1016/j.coi.2010.05.004
10. Middendorp S., Nieuwenhuis E. E. S., NKT cells in mucosal immunity. Mucosal Immunology 2009 2 5 393 402 2-s2.0-69249113500 10.1038/mi.2009.99
11. Bernink J. H., Peters C. P., Munneke M., Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues. Nature Immunology 2013 14 221 229 10.1038/ni.2534
12. Xu H., Wang X., Liu D. X., Moroney-Rasmussen T., Lackner A. A., Veazey R. S., IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques. Mucosal Immunology 2012 5 658 669 10.1038/mi.2012.39
13. Berzins S. P., Smyth M. J., Baxter A. G., Presumed guilty: natural killer T cell defects and human disease. Nature Reviews Immunology 2011 11 2 131 142 2-s2.0-79251497664 10.1038/nri2904
14. Walker J. A., Barlow J. L., McKenzie A. N., Innate lymphoid cells-how did we miss them? Nature Reviews Immunology 2013 13 75 87 10.1038/nri3349
15. Spits H., Artis D., Colonna M., Innate lymphoid cells-a proposal for uniform nomenclature. Nature Reviews Immunology 2013 13 145 149 10.1038/nri3365
16. Spits H., di Santo J. P., The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nature Immunology 2011 12 1 21 27 2-s2.0-78650310810 10.1038/ni.1962
17. Vonarbourg C., Diefenbach A., Multifaceted roles of interleukin-7 signaling for the development and function of innate lymphoid cells. Seminars Immunology 2012 24 3 165 174 10.1016/j.smim.2012.03.002
18. Walker J. A., McKenzie A. N., Development and function of group 2 innate lymphoid cells. Current Opinion Immunology 2013 25 2 148 155 10.1016/j.coi.2013.02.010
19. Vosshenrich C. A., di Santo J. P., Developmental programming of natural killer and innate lymphoid cells. Current Opinion Immunology 2013 25 2 130 138 10.1016/j.coi.2013.02.002
20. Cherrier M., Ohnmacht C., Cording S., Eberl G., Development and function of intestinal innate lymphoid cells. Current Opinion Immunology 2012 24 3 277 283 10.1016/j.coi.2012.03.011
21. Possot C., Schmutz S., Chea S., Boucontet L., Louise A., Cumano A., Golub R., Notch signaling is necessary for adult, but not fetal, development of ROR γ (+) innate lymphoid cells. Nature Immunology 2011 12 10 949 958 2-s2.0-80052970974 10.1038/ni.2105
22. Cherrier M., Sawa S., Eberl G., Notch, Id2, and ROR γ t sequentially orchestrate the fetal development of lymphoid tissue inducer cells. Journal of Experimental Medicine 2012 209 4 729 740 10.1084/jem.20111594
23. Mjosberg J., Bernink J., Peters C., Spits H., Transcriptional control of innate lymphoid cells. European Journal of Immunology 2012 42 8 1916 1923 10.1002/eji.201242639
24. Ahn Y. O., Blazar B. R., Miller J. S., Verneris M. R., Lineage relationships of human interleukin-22-producing CD56+ ROR γ t+ innate lymphoid cells and conventional natural killer cells. Blood 2013 121 12 2234 2243 10.1182/blood-2012-07-440099
25. Hoyler T., Klose C. S., Souabni A., The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity 2012 37 4 634 648 10.1016/j.immuni.2012.06.020
26. Zhou L., Striking similarity: GATA-3 regulates ILC2 and Th2 cells. Immunity 2012 37 4 589 591 10.1016/j.immuni.2012.10.002
27. Romera-Hernandez M., Aparicio-Domingo P., Cupedo T., Damage control: Ror γ t+ innate lymphoid cells in tissue regeneration. Current Opinion Immunology 2013 25 2 156 160 10.1016/j.coi.2013.01.007
28. Spits H., Cupedo T., Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annual Review of Immunology 2012 30 647 675 2-s2.0-84859384082 10.1146/annurev-immunol-020711-075053
29. Wong S. H., Walker J. A., Jolin H. E., Transcription factor ROR is critical for nuocyte development. Nature Immunology 2012 13 229 236 10.1038/ni.2208
30. Mosmann T. R., Cherwinski H., Bond M. W., Giedlin M. A., Coffman R. L., Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. Journal of Immunology 1986 136 7 2348 2357 2-s2.0-0022640843 (Pubitemid 16136806)
31. Zhou L., Chong M. M. W., Littman D. R., Plasticity of CD4+ T cell lineage differentiation. Immunity 2009 30 5 646 655 2-s2.0-65549115862 10.1016/j.immuni.2009.05.001
32. Locksley R. M., Nine lives: plasticity among T helper cell subsets. Journal of Experimental Medicine 2009 206 8 1643 1646 2-s2.0-68149156013 10.1084/jem.20091442
33. Murphy K. M., Stockinger B., Effector T cell plasticity: flexibility in the face of changing circumstances. Nature Immunology 2010 11 8 674 680 2-s2.0-77954948735 10.1038/ni.1899
34. O'Shea J., Paul W. E., Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science 2010 327 5969 1098 1102 2-s2.0-77649220954 10.1126/science.1178334
35. Mattner J., Natural killer T, (NKT) cells in autoimmune hepatitis. Current Opinion Immunology 2013 25 6 697 703 10.1016/j.coi.2013.09.008
36. Beckman E. M., Porcelli S. A., Morita C. T., Behar S. M., Furlong S. T., Brenner M. B., Recognition of lipid antigen by CD1-restricted β + T cells. Nature 1994 372 6507 691 694 2-s2.0-0028588920
37. Bendelac A., Lantz O., Quimby M. E., Yewdell J. W., Bennink J. R., Brutkiewicz R. R., CD1 recognition by mouse NK1+ T lymphocytes. Science 1995 268 5212 863 865 2-s2.0-0029029565
38. Kawano T., Cui J., Koezuka Y., CD1d-restricted and TCR-mediated activation of V 14 NKT cells by glycosylceramides. Science 1997 278 5343 1626 1629 10.1126/science.278.5343.1626 (Pubitemid 27516282)
39. Bendelac A., Savage P. B., Teyton L., The biology of NKT cells. Annual Review of Immunology 2007 25 297 336 2-s2.0-34247842744 10.1146/annurev.immunol. 25.022106.141711 (Pubitemid 46697911)
40. Wei D. G., Lee H., Park S.-H., Beaudoin L., Teyton L., Lehuen A., Bendelac A., Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. Journal of Experimental Medicine 2005 202 2 239 248 2-s2.0-22944442645 10.1084/jem.20050413 (Pubitemid 41043820)
41. Das R., Sant'Angelo D. B., Nichols K. E., Transcriptional control of invariant NKT cell development. Immunological Reviews 2010 238 1 195 215 2-s2.0-77958521230 10.1111/j.1600-065X.2010.00962.x
42. Berzins S. P., Uldrich A. P., Pellicci D. G., Mcnab F., Hayakawa Y., Smyth M. J., Godfrey D. I., Parallels and distinctions between T and NKT cell development in the thymus. Immunology and Cell Biology 2004 82 3 269 275 2-s2.0-3042847448 10.1111/j.0818-9641.2004.01256.x (Pubitemid 38870021)
43. Gapin L., The making of NKT cells. Nature Immunology 2008 9 9 1009 1011 2-s2.0-50049093377 10.1038/ni0908-1009
44. Gleimer M., von Boehmer H., Kreslavsky T., PLZF controls the expression of a limited number of genes essential for NKT cell function. Frontiers in Immunology 2012 3, article 374 10.3389/fimmu.2012.00374
45. Constantinides M. G., Bendelac A., Transcriptional regulation of the NKT cell lineage. Current Opinion Immunology 2013 25 2 161 167 10.1016/j.coi.2013. 01.003
46. Lee Y. J., Holzapfel K. L., Zhu J., Jameson S. C., Hogquist K. A., Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. Nature Immunology 2013 14 1146 1154 10.1038/ni.2731
47. Raifer H., Mahiny A.J., Bollig N., Unlike β T cells, γ δ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22. European Journal of Immunology 2012 42 12 3189 3201 10.1002/eji.201142155
48. Philip N. H., Artis D., New friendships and old feuds: relationships between innate lymphoid cells and microbial communities. Immunology and Cell Biology 2013 91 225 231 10.1038/icb.2013.2
49. Diefenbach A., Innate lymphoid cells in the defense against infections. European Journal of Microbiology and Immunology 2013 3 3 143 151 10.1556/EuJMI.3.2013.3.1
50. Brennan P. J., Brigl M., Brenner M. B., Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nature Reviews Immunology 2013 13 101 117 10.1038/nri3369
51. Paget C., Mallevaey T., Speak A. O., Torres D., Fontaine J., Sheehan K. C. F., Capron M., Ryffel B., Faveeuw C., Leite de Moraes M., Platt F., Trottein F., Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity 2007 27 4 597 609 2-s2.0-35448936431 10.1016/j.immuni.2007.08.017 (Pubitemid 47628833)
52. Goto M., Murakawa M., Kadoshima-Yamaoka K., Tanaka Y., Nagahira K., Fukuda Y., Nishimura T., Murine NKT cells produce Th17 cytokine interleukin-22. Cellular Immunology 2009 254 2 81 84 2-s2.0-57249096982 10.1016/j.cellimm.2008. 10.002
53. Doisne J.-M., Soulard V., Bécourt C., Amniai L., Henrot P., Havenar-Daughton C., Blanchet C., Zitvogel L., Ryffel B., Cavaillon J.-M., Marie J. C., Couillin I., Benlagha K., Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria. Journal of Immunology 2011 186 2 662 666 2-s2.0-79251578351 10.4049/jimmunol.1002725
54. Matsuda J. L., Gapin L., Baron J. L., Sidobre S., Stetson D. B., Mohrs M., Locksley R. M., Kronenberg M., Mouse V 14i natural killer T cells are resistant to cytokine polarization in vivo. Proceedings of the National Academy of Sciences of the United States of America 2003 100 14 8395 8400 2-s2.0-0037816187 10.1073/pnas.1332805100 (Pubitemid 36842556)
55. Wencker M., Turchinovich G., di Marco Barros R., Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness. Nature Immunology 2014 15 80 87 10.1038/ni.2773
56. Mattner J., Debord K. L., Ismail N., Goff R. D., Cantu C. III, Zhou D., Saint-Mezard P., Wang V., Gao Y., Yin N., Hoebe K., Schneewind O., Walker D., Beutler B., Teyton L., Savage P. B., Bendelac A., Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005 434 7032 525 529 2-s2.0-31444439715 10.1038/nature04475 (Pubitemid 40477062)
57. Kinjo Y., Wu D., Kim G., Xing G.-W., Poles M. A., Ho D. D., Tsuji M., Kawahara K., Wong C.-H., Kronenberg M., Recognition of bacterial glycosphingolipids by natural killer T cells. Nature 2005 434 7032 520 525 2-s2.0-15844421595 10.1038/nature03407 (Pubitemid 40477061)
58. Kinjo Y., Tupin E., Wu D., Fujio M., Garcia-Navarro R., Benhnia M. R.-E., Zajonc D. M., Ben-Menachem G., Ainge G. D., Painter G. F., Khurana A., Hoebe K., Behar S. M., Beutler B., Wilson I. A., Tsuji M., Sellati T. J., Wong C.-H., Kronenberg M., Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nature Immunology 2006 7 9 978 986 2-s2.0-33747607029 10.1038/ni1380 (Pubitemid 44263912)
59. Kinjo Y., Illarionov P., Vela J. L., Pei B., Girardi E., Li X., Li Y., Imamura M., Kaneko Y., Okawara A., Miyazaki Y., Gómez-Velasco A., Rogers P., Dahesh S., Uchiyama S., Khurana A., Kawahara K., Yesilkaya H., Andrew P. W., Wong C.-H., Kawakami K., Nizet V., Besra G. S., Tsuji M., Zajonc D. M., Kronenberg M., Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nature Immunology 2011 12 10 966 974 2-s2.0-80052966551 10.1038/ni.2096
60. Amprey J. L., Im J. S., Turco S. J., Murray H. W., Illarionov P. A., Besra G. S., Porcelli S. A., Späth G. F., A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan. Journal of Experimental Medicine 2004 200 7 895 904 2-s2.0-5444259450 10.1084/jem.20040704 (Pubitemid 39362925)
61. Fischer K., Scotet E., Niemeyer M., Koebernick H., Zerrahn J., Maillet S., Hurwitz R., Kursar M., Bonneville M., Kaufmann S. H. E., Schaible U. E., Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells. Proceedings of the National Academy of Sciences of the United States of America 2004 101 29 10685 10690 2-s2.0-3242709268 10.1073/pnas.0403787101 (Pubitemid 38955803)
62. Geissmann F., Cameron T. O., Sidobre S., Manlongat N., Kronenberg M., Briskin M. J., Dustin M. L., Littman D. R., Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids. PLoS Biology 2005 3 4, article e113 2-s2.0-33644874999 10.1371/journal.pbio.0030113 (Pubitemid 40721158)
63. Velázquez P., Cameron T. O., Kinjo Y., Nagarajan N., Kronenberg M., Dustin M. L., Cutting edge: activation by innate cytokines or microbial antigens can cause arrest of natural killer T cell patrolling of liver sinusoids. Journal of Immunology 2008 180 4 2024 2028 2-s2.0-42149087124
64. Parekh V. V., Wilson M. T., Olivares-Villagómez D., Singh A. K., Wu L., Wang C.-R., Joyce S., Van Kaer L., Glycolipid antigen induces long-term natural killer T cell anergy in mice. Journal of Clinical Investigation 2005 115 9 2572 2583 2-s2.0-24644433401 10.1172/JCI24762 (Pubitemid 41266220)
65. Kimura K., Kanai T., Hayashi A., Dysregulated balance of retinoid-related orphan receptor γ t-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis. Biochemical and Biophysical Research Communications 2012 427 694 700 10.1016/j.bbrc.2012.09.091
66. Li B. W., Hendriks R. W., Group 2 innate lymphoid cells in lung inflammation. Immunology 2013 140 3 281 287 10.1111/imm.12153
67. Scanlon S. T., McKenzie A. N., Type 2 innate lymphoid cells: new players in asthma and allergy. Current Opinion Immunology 2012 24 6 707 712 10.1016/j.coi.2012.08.009
68. Halim T. Y., McKenzie A. N., New kids on the block: group 2 innate lymphoid cells and type 2 inflammation in the lung. Chest 2013 144 1681 1686 10.1378/chest.13-0911
69. Deckers J., Branco Madeira F., Hammad H., Innate immune cells in asthma. Trends Immunology 2013 34 11 540 547 10.1016/j.it.2013.08.004
70. Erpenbeck V. J., Hohlfeld J. M., Volkmann B., Hagenberg A., Geldmacher H., Braun A., Krug N., Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes. Journal of Allergy and Clinical Immunology 2003 111 6 1319 1327 2-s2.0-0038518063 10.1067/mai.2003.1485 (Pubitemid 36683688)
71. Shimbara A., Christodoulopoulos P., Soussi-Gounni A., Olivenstein R., Nakamura Y., Levitt R. C., Nicolaides N. C., Holroyd K. J., Tsicopoulos A., Lafitte J.-J., Wallaert B., Hamid Q. A., IL-9 and its receptor in allergic and nonallergic lung disease: increased expression in asthma. Journal of Allergy and Clinical Immunology 2000 105 1 I 108 115 2-s2.0-4444262198 (Pubitemid 30059110)
72. Kim H. Y., Lee H. J., Yang Y. J., Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity. Nature Medicine 2014 20 54 61 10.1038/nm.3423
73. Umetsu D. T., DeKruyff R. H., Natural killer T cells are important in the pathogenesis of asthma: the many pathways to asthma. Journal of Allergy and Clinical Immunology 2010 125 5 975 979 2-s2.0-77951666927 10.1016/j.jaci.2010. 02.006
74. Iwamura C., Nakayama T., Role of NKT cells in allergic asthma. Current Opinion in Immunology 2010 22 6 807 813 2-s2.0-78649848463 10.1016/j.coi.2010. 10.008
75. Minai-Fleminger Y., Levi-Schaffer F., Mast cells and eosinophils: the two key effector cells in allergic inflammation. Inflammation Research 2009 58 10 631 638 2-s2.0-70349301398 10.1007/s00011-009-0042-6
76. Amin K., The role of mast cells in allergic inflammation. Respiratory Medicine 2012 106 1 9 14 2-s2.0-82955233553 10.1016/j.rmed.2011.09.007
77. Rayapudi M., Rajavelu P., Zhu X., Invariant natural killer T-cell neutralization is a possible novel therapy for human eosinophilic esophagitis. Clinical and Translational Immunology 2014 3, article e9 10.1038/cti.2013.13
78. Albacker L. A., Chaudhary V., Chang Y. J., Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity. Nature Medicine 2013 19 1297 1304 10.1038/nm.3321
79. Agea E., Russano A., Bistoni O., Mannucci R., Nicoletti I., Corazzi L., Postle A. D., De Libero G., Porcelli S. A., Spinozzi F., Human CD1-restricted T cell recognition of lipids from pollens. Journal of Experimental Medicine 2005 202 2 295 308 2-s2.0-22944439737 10.1084/jem.20050773 (Pubitemid 41043825)
80. Hachem P., Lisbonne M., Michel M.-L., Diem S., Roongapinun S., Lefort J., Marchal G., Herbelin A., Askenase P. W., Dy M., Leite-de-Moraes M. C., -galactosylceramide-induced iNKT cells suppress experimental allergic asthma in sensitized mice: role in IFN- γ European Journal of Immunology 2005 35 10 2793 2802 2-s2.0-27644586260 10.1002/eji.200535268 (Pubitemid 41555076)
81. Matsuda H., Suda T., Sato J., Nagata T., Koide Y., Chida K., Nakamura H., -galactosylceramide, a ligand of natural killer T cells, inhibits allergic airway inflammation. The American Journal of Respiratory Cell and Molecular Biology 2005 33 1 22 31 2-s2.0-21844476225 10.1165/rcmb.2004-0010OC (Pubitemid 40961010)
82. Licona-Limon P., Kim L. K., Palm N. W., Flavell R. A., TH2, allergy and group 2 innate lymphoid cells. Nature Immunology 2013 14 536 542 10.1038/ni.2617
83. Barlow J. L., Peel S., Fox J., IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. Journal of Allergy and Clinical Immunology 2013 132 4 933 941 10.1016/j.jaci.2013.05.012
84. Meylan F., Hawley E. T., Barron L., The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells. Mucosal Immunology 2013 10.1038/mi.2013.114
85. Zeng D., Liu Y., Sidobre S., Kronenberg M., Strober S., Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. Journal of Clinical Investigation 2003 112 8 1211 1222 2-s2.0-0347988004 10.1172/JCI200317165 (Pubitemid 38056298)
86. Forestier C., Molano A., Im J. S., Dutronc Y., Diamond B., Davidson A., Illarionov P. A., Besra G. S., Porcelli S. A., Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black × New Zealand White)F1 mice. Journal of Immunology 2005 175 2 763 770 2-s2.0-23244447028 (Pubitemid 41094957)
87. Vultaggio A., Nencini F., Pratesi S., Poly(I:C) promotes the production of IL-17A by murine CD1d-driven invariant NKT cells in airway inflammation. Allergy 2012 67 10 1223 1232 10.1111/j.1398-9995.2012.02876.x.
88. Choi J. P., Kim Y. M., Choi H. I., An important role of tumor necrosis factor receptor-2 on natural killer T cells on the development of dsRNA-enhanced Th2 cell response to inhaled allergens. Allergy 2013 69 2 186 198 10.1111/all.12301
89. Wu L., van Kaer L., Natural killer T cells and autoimmune disease. Current Molecular Medicine 2009 9 1 4 14 2-s2.0-62749198174 10.2174/ 156652409787314534
90. Rutz S., Eidenschenk C., Ouyang W., IL-22, not simply a Th17 cytokine. Immunological Reviews 2013 252 1 116 132 10.1111/imr.12027
91. Taube C., Tertilt C., Gyülveszi G., Dehzad N., Kreymborg K., Schneeweiss K., Michel E., Reuter S., Renauld J.-C., Arnold-Schild D., Schild H., Buhl R., Becher B., IL-22 is produced by innate lymphoid cells and limits inflammation in allergic airway disease. PLoS ONE 2011 6 7 2-s2.0-79960581219 10.1371/journal.pone.0021799 e21799
92. Li H., Reeves R. K., Functional perturbation of classical natural killer and innate lymphoid cells in the oral mucosa during SIV infection. Frontiers Immunology 2012 3, article 417 10.3389/fimmu.2012.00417
93. Wolk K., Witte E., Witte K., Warszawska K., Sabat R., Biology of interleukin-22. Seminars in Immunopathology 2010 32 1 17 31 2-s2.0-77949656872 10.1007/s00281-009-0188-x
94. Sawa S., Lochner M., Satoh-Takayama N., Dulauroy S., Bérard M., Kleinschek M., Cua D., di Santo J. P., Eberl G., ROR γ t(+) innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nature Immunology 2011 12 4 320 326 2-s2.0-79952986650 10.1038/ni.2002
95. Qu N., Xu M., Mizoguchi I., Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases. Clinical and Developmental Immunology 2013 2013 13 968549 10.1155/2013/968549
96. Roberts-Thomson I. C., Fon J., Uylaki W., Cummins A. G., Barry S., Cells, cytokines and inflammatory bowel disease: a clinical perspective. Expert Review of Gastroenterology and Hepatology 2011 5 6 703 716 2-s2.0-80155182156 10.1586/egh.11.74
97. Kanai T., Mikami Y., Sujino T., Hisamatsu T., Hibi T., ROR γ t-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation. Mucosal Immunology 2012 5 3 240 247 2-s2.0-84859879397 10.1038/mi.2012.6
98. Sutton C. E., Mielke L. A., Mills K. H., IL-17-producing γ δ T cells and innate lymphoid cells. European Journal of Immunology 2012 42 9 2221 2231 10.1002/eji.201242569
99. Geremia A., Arancibia-Cárcamo C. V., Fleming M. P. P., Rust N., Singh B., Mortensen N. J., Travis S. P. L., Powrie F., IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease. Journal of Experimental Medicine 2011 208 6 1127 1133 2-s2.0-79958277385 10.1084/jem.20101712
100. Eken A., Singh A. K., Treuting P. M., Oukka M., IL-23R(+) innate lymphoid cells induce colitis via interleukin-22-dependent mechanism. Mucosal Immunology 2014 7 143 154 10.1038/mi.2013.33
101. Powell N., Walker A. W., Stolarczyk E., The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity 2012 37 4 674 684 10.1016/j.immuni.2012.09.008
102. Behnsen J., Raffatellu M., Keeping the peace: aryl hydrocarbon receptor signaling modulates the mucosal microbiota. Immunity 2013 39 2 206 207 10.1016/j.immuni.2013.08.012
103. Buonocore S., Ahern P. P., Uhlig H. H., Ivanov I. I., Littman D. R., Maloy K. J., Powrie F., Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 2010 464 7293 1371 1375 2-s2.0-77951878587 10.1038/nature08949
104. Geremia A., Arancibia-Cárcamo C. V., Fleming M. P. P., Rust N., Singh B., Mortensen N. J., Travis S. P. L., Powrie F., IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease. Journal of Experimental Medicine 2011 208 6 1127 1133 2-s2.0-79958277385 10.1084/jem.20101712
105. Fuss I. J., Strober W., The role of IL-13 and NK T cells in experimental and human ulcerative colitis. Mucosal Immunology 2008 1 supplement 1 S31 S33 2-s2.0-54349118972 10.1038/mi.2008.40
106. Liao C., Zimmer M. I., Shanmuganad S., Yu H., Cardell S. L., Wang C., Dysregulation of CD1d-restricted type II natural killer T cells leads to spontaneous development of colitis in mice. Gastroenterology 2012 142 2 326 334 2-s2.0-84856235126 10.1053/j.gastro.2011.10.030
107. Olszak T., An D., Zeissig S., Vera M. P., Richter J., Franke A., Glickman J. N., Siebert R., Baron R. M., Kasper D. L., Blumberg R. S., Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012 336 6080 489 493 2-s2.0-84860216630 10.1126/science. 1219328
108. Wingender G., Stepniak D., Krebs P., Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology 2012 143 2 418 428 10.1053/j.gastro.2012.04.017
109. Terashima A., Watarai H., Inoue S., Sekine E., Nakagawa R., Hase K., Iwamura C., Nakajima H., Nakayama T., Taniguchi M., A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity. Journal of Experimental Medicine 2008 205 12 2727 2733 2-s2.0-58149289887 10.1084/jem.2008069e
110. Camelo A., Barlow J. L., Drynan L. F., Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13. Journal of Gastroenterology 2012 47 11 1198 1211 10.1007/s00535-012-0591-2
111. Gorski S. A., Hahn Y. S., Braciale T. J., Group 2 innate lymphoid cell production of IL-5 is regulated by NKT cells during influenza virus infection. PLoS Pathogogens 2013 9 e1003615 10.1371/journal.ppat.1003615