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Volumn 5, Issue 6, 2011, Pages 703-716

Cells, cytokines and inflammatory bowel disease: A clinical perspective

Author keywords

Crohn's disease; cytokines; inflammatory cells; pathogenesis of disease; ulcerative colitis

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CD14 ANTIGEN; CD2 ANTIGEN; CD209 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45RA ANTIGEN; CD8 ANTIGEN; CYTOKINE; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; PHOSPHOLIPASE A2; PROTEIN KINASE C; SELECTIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 80155182156     PISSN: 17474124     EISSN: 17474132     Source Type: Journal    
DOI: 10.1586/egh.11.74     Document Type: Review
Times cited : (101)

References (102)
  • 1
    • 0029948461 scopus 로고    scopus 로고
    • Pathogenesis of aphthoid ulcers in Crohns disease: Correlative findings by magnifying colonoscopy electron microscopy and immunohistochemistry
    • Fujimura Y, Kamoi R, Iida M. Pathogenesis of aphthoid ulcers in Crohn's disease: correlative findings by magnifying colonoscopy, electron microscopy, and immunohistochemistry. Gut 38(5), 724-732 (1996).
    • (1996) Gut , vol.38 , Issue.5 , pp. 724-732
    • Fujimura, Y.1    Kamoi, R.2    Iida, M.3
  • 2
    • 0033180298 scopus 로고    scopus 로고
    • Type 1 T-helper cell predominance in granulomas of Crohns disease
    • Kakazu T, Hara J, Matsumoto T et al. Type 1 T-helper cell predominance in granulomas of Crohn's disease. Am. J. Gastroenterol. 94(8), 2149-2155 (1999).
    • (1999) Am. J. Gastroenterol. , vol.94 , Issue.8 , pp. 2149-2155
    • Kakazu, T.1    Hara, J.2    Matsumoto, T.3
  • 3
    • 0021364710 scopus 로고
    • Rectal biopsy helps to distinguish acute self-limited colitis from idiopathic inflammatory bowel disease
    • Surawicz CM, Belic L. Rectal biopsy helps to distinguish acute self-limited colitis from idiopathic inflammatory bowel disease. Gastroenterology 86(1), 104-113 (1984).
    • (1984) Gastroenterology , vol.86 , Issue.1 , pp. 104-113
    • Surawicz, C.M.1    Belic, L.2
  • 4
    • 0023495541 scopus 로고
    • The value of rectal biopsy in distinguishing self-limited colitis from early inflammatory bowel disease
    • Allison MC, Hamilton-Dutoit SJ, Dhillon AP, Pounder RE. The value of rectal biopsy in distinguishing self-limited colitis from early inflammatory bowel disease. Q. J. Med. 65(248), 985-995 (1987).
    • (1987) Q. J. Med. , vol.65 , Issue.248 , pp. 985-995
    • Allison, M.C.1    Hamilton-Dutoit, S.J.2    Dhillon, A.P.3    Pounder, R.E.4
  • 5
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
    • Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124(4), 823-835 (2006).
    • (2006) Cell , vol.124 , Issue.4 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 6
    • 33846823024 scopus 로고    scopus 로고
    • Resolution of inflammation: State of the art definitions and terms
    • Serhan CN, Brain SD, Buckley CD et al. Resolution of inflammation: state of the art, definitions and terms. FASEB J. 21(2), 325-332 (2007).
    • (2007) FASEB J. , vol.21 , Issue.2 , pp. 325-332
    • Serhan, C.N.1    Brain, S.D.2    Buckley, C.D.3
  • 7
    • 38849133044 scopus 로고    scopus 로고
    • A calculated response: Control of inflammation by the innate immune system
    • Barton GM. A calculated response: control of inflammation by the innate immune system. J. Clin. Invest. 118(2), 413-420 (2008).
    • (2008) J. Clin. Invest. , vol.118 , Issue.2 , pp. 413-420
    • Barton, G.M.1
  • 8
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. Origin and physiological roles of inflammation. Nature 454(7203), 428-435 (2008).
    • (2008) Nature , vol.454 , Issue.7203 , pp. 428-435
    • Medzhitov, R.1
  • 9
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8(5), 349-361 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.5 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 10
    • 78650408264 scopus 로고    scopus 로고
    • Diet gut microbiota and immune responses
    • Maslowski KM, Mackay CR. Diet, gut microbiota and immune responses. Nat. Immunol. 12(1), 5-9 (2011).
    • (2011) Nat. Immunol. , vol.12 , Issue.1 , pp. 5-9
    • Maslowski, K.M.1    Mackay, C.R.2
  • 11
    • 4644303010 scopus 로고    scopus 로고
    • Relationship between fecal calprotectin intestinal inflammation and peripheral blood neutrophils in patients with active ulcerative colitis
    • Hanai H, Takeuchi K, Iida T et al. Relationship between fecal calprotectin, intestinal inflammation, and peripheral blood neutrophils in patients with active ulcerative colitis. Dig. Dis. Sci. 49(9), 1438-1443 (2004).
    • (2004) Dig. Dis. Sci. , vol.49 , Issue.9 , pp. 1438-1443
    • Hanai, H.1    Takeuchi, K.2    Iida, T.3
  • 12
    • 0035097038 scopus 로고    scopus 로고
    • Gut luminal neutrophil migration is influenced by the anatomical site of crohns disease
    • Arnott ID, Drummond HE, Ghosh S. Gut luminal neutrophil migration is influenced by the anatomical site of Crohn's disease. Eur. J. Gastroenterol. Hepatol. 13(3), 239-243 (2001).
    • (2001) Eur. J. Gastroenterol. Hepatol. , vol.13 , Issue.3 , pp. 239-243
    • Arnott, I.D.1    Drummond, H.E.2    Ghosh, S.3
  • 13
    • 0032014268 scopus 로고    scopus 로고
    • Correlations between interleukin-8 and myeloperoxidase or luminol-dependent chemiluminescence in inflamed mucosa of ulcerative colitis
    • Anezaki K, Asakura H, Honma T et al. Correlations between interleukin-8, and myeloperoxidase or luminol-dependent chemiluminescence in inflamed mucosa of ulcerative colitis. Intern. Med. 37(3), 253-258 (1998).
    • (1998) Intern. Med. , vol.37 , Issue.3 , pp. 253-258
    • Anezaki, K.1    Asakura, H.2    Honma, T.3
  • 14
    • 0025721860 scopus 로고
    • Peripheral blood neutrophils in inflammatory bowel disease: Morphological evidence of in vivo activation in active disease
    • Mccarthy DA, Rampton DS, Liu YC. Peripheral blood neutrophils in inflammatory bowel disease: morphological evidence of in vivo activation in active disease. Clin. Exp. Immunol. 86(3), 489-493 (1991).
    • (1991) Clin. Exp. Immunol. , vol.86 , Issue.3 , pp. 489-493
    • Mccarthy, D.A.1    Rampton, D.S.2    Liu, Y.C.3
  • 15
    • 0031903013 scopus 로고    scopus 로고
    • Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation
    • Nikolaus S, Bauditz J, Gionchetti P, Witt C, Lochs H, Schreiber S. Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation. Gut 42(4), 470-476 (1998).
    • (1998) Gut , vol.42 , Issue.4 , pp. 470-476
    • Nikolaus, S.1    Bauditz, J.2    Gionchetti, P.3    Witt, C.4    Lochs, H.5    Schreiber, S.6
  • 16
    • 0036282421 scopus 로고    scopus 로고
    • Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis
    • Carlson M, Raab Y, Seveus L, Xu S, Hallgren R, Venge P. Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis. Gut 50(4), 501-506 (2002).
    • (2002) Gut. , vol.50 , Issue.4 , pp. 501-506
    • Carlson, M.1    Raab, Y.2    Seveus, L.3    Xu, S.4    Hallgren, R.5    Venge, P.6
  • 17
    • 33344466383 scopus 로고    scopus 로고
    • Defective acute inflammation in crohns disease: A clinical investigation
    • Marks DJ, Harbord MW, Macallister R et al. Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet 367(9511), 668-678 (2006).
    • (2006) Lancet , vol.367 , Issue.9511 , pp. 668-678
    • Marks, D.J.1    Harbord, M.W.2    Macallister, R.3
  • 19
    • 35449005786 scopus 로고    scopus 로고
    • Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease
    • Naito Y, Takagi T, Yoshikawa T. Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease. J. Gastroenterol. 42(10), 787-798 (2007).
    • (2007) J. Gastroenterol. , vol.42 , Issue.10 , pp. 787-798
    • Naito, Y.1    Takagi, T.2    Yoshikawa, T.3
  • 20
    • 69449105914 scopus 로고    scopus 로고
    • Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in crohns disease
    • Smith AM, Rahman FZ, Hayee BH et al. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J. Exp. Med. 206, 1883-1897 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 1883-1897
    • Smith, A.M.1    Rahman, F.Z.2    Hayee, B.H.3
  • 22
    • 77958479785 scopus 로고    scopus 로고
    • The role of the macrophage in sentinel responses in intestinal immunity
    • Sheikh SZ, Plevy SE. The role of the macrophage in sentinel responses in intestinal immunity. Curr. Opin. Gastroenterol. 26(6), 578-582 (2010).
    • (2010) Curr. Opin. Gastroenterol. , vol.26 , Issue.6 , pp. 578-582
    • Sheikh, S.Z.1    Plevy, S.E.2
  • 23
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8(12), 958-969 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 24
    • 77954096426 scopus 로고    scopus 로고
    • A systems biology viewpoint on autophagy in health and disease
    • Huett A, Goel G, Xavier RJ. A systems biology viewpoint on autophagy in health and disease. Curr. Opin. Gastroenterol. 26(4), 302-309 (2010).
    • (2010) Curr. Opin. Gastroenterol. , vol.26 , Issue.4 , pp. 302-309
    • Huett, A.1    Goel, G.2    Xavier, R.J.3
  • 25
    • 45749107055 scopus 로고    scopus 로고
    • Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-g axis
    • Kamada N, Hisamatsu T, Okamoto S et al. Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-g axis. J. Clin. Invest. 118(6), 2269-2280 (2008).
    • (2008) J. Clin. Invest. , vol.118 , Issue.6 , pp. 2269-2280
    • Kamada, N.1    Hisamatsu, T.2    Okamoto, S.3
  • 26
    • 68149183243 scopus 로고    scopus 로고
    • + macrophages in intestinal lamina propria exhibit potent antigen-presenting ability
    • + macrophages in intestinal lamina propria exhibit potent antigen-presenting ability. J. Immunol. 183(3), 1724-1731 (2009).
    • (2009) J. Immunol. , vol.183 , Issue.3 , pp. 1724-1731
    • Kamada, N.1    Hisamatsu, T.2    Honda, H.3
  • 28
    • 24644486437 scopus 로고    scopus 로고
    • Stepwise regulation of TH1 responses in autoimmunity: IL-12-related cytokines and their receptors
    • Becker C, Wirtz S, Neurath MF. Stepwise regulation of TH1 responses in autoimmunity: IL-12-related cytokines and their receptors. Inflamm. Bowel Dis. 11(8), 755-764 (2005).
    • (2005) Inflamm. Bowel Dis. , vol.11 , Issue.8 , pp. 755-764
    • Becker, C.1    Wirtz, S.2    Neurath, M.F.3
  • 29
    • 35848958662 scopus 로고    scopus 로고
    • New players in the cytokine orchestra of inflammatory bowel disease
    • Fantini MC, Monteleone G, Macdonald TT. New players in the cytokine orchestra of inflammatory bowel disease. Inflamm. Bowel Dis. 13(11), 1419-1423 (2007).
    • (2007) Inflamm. Bowel Dis. , vol.13 , Issue.11 , pp. 1419-1423
    • Fantini, M.C.1    Monteleone, G.2    Macdonald, T.T.3
  • 30
    • 51249111466 scopus 로고    scopus 로고
    • The role of T-regulatory cells and Toll-like receptors in the pathogenesis of human inflammatory bowel disease
    • Himmel ME, Hardenberg G, Piccirillo CA, Steiner TS, Levings MK. The role of T-regulatory cells and Toll-like receptors in the pathogenesis of human inflammatory bowel disease. Immunology 125(2), 145-153 (2008).
    • (2008) Immunology , vol.125 , Issue.2 , pp. 145-153
    • Himmel, M.E.1    Hardenberg, G.2    Piccirillo, C.A.3    Steiner, T.S.4    Levings, M.K.5
  • 31
    • 56649106476 scopus 로고    scopus 로고
    • Interplay between effector Th17 and regulatory T cells
    • Awasthi A, Murugaiyan G, Kuchroo VK. Interplay between effector Th17 and regulatory T cells. J. Clin. Immunol. 28(6), 660-670 (2008).
    • (2008) J. Clin. Immunol. , vol.28 , Issue.6 , pp. 660-670
    • Awasthi, A.1    Murugaiyan, G.2    Kuchroo, V.K.3
  • 34
    • 79952300978 scopus 로고    scopus 로고
    • Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases
    • Hovhannisyan Z, Treatman J, Littman DR, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology 140, 957-965 (2011).
    • (2011) Gastroenterology , vol.140 , pp. 957-965
    • Hovhannisyan, Z.1    Treatman, J.2    Littman, D.R.3    Mayer, L.4
  • 36
    • 77958475318 scopus 로고    scopus 로고
    • Intestinal dendritic cells
    • Rescigno M. Intestinal dendritic cells. Adv. Immunol. 107, 109-138 (2010).
    • (2010) Adv. Immunol. , vol.107 , pp. 109-138
    • Rescigno, M.1
  • 37
    • 12144288485 scopus 로고    scopus 로고
    • Increased expression of CCL20 in human inflammatory bowel disease
    • Kaser A, Ludwiczek O, Holzmann S et al. Increased expression of CCL20 in human inflammatory bowel disease. J. Clin. Immunol. 24(1), 74-85 (2004).
    • (2004) J. Clin. Immunol. , vol.24 , Issue.1 , pp. 74-85
    • Kaser, A.1    Ludwiczek, O.2    Holzmann, S.3
  • 38
    • 12344290269 scopus 로고    scopus 로고
    • Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells
    • Baumgart DC, Metzke D, Schmitz J et al. Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells. Gut 54(2), 228-236 (2005).
    • (2005) Gut , vol.54 , Issue.2 , pp. 228-236
    • Baumgart, D.C.1    Metzke, D.2    Schmitz, J.3
  • 39
    • 22344448660 scopus 로고    scopus 로고
    • Characteristics of intestinal dendritic cells in inflammatory bowel diseases
    • Hart AL, Al-Hassi HO, Rigby RJ et al. Characteristics of intestinal dendritic cells in inflammatory bowel diseases. Gastroenterology 129(1), 50-65 (2005).
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 50-65
    • Hart, A.L.1    Al-Hassi, H.O.2    Rigby, R.J.3
  • 40
    • 70350093623 scopus 로고    scopus 로고
    • Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in crohns disease
    • Sakuraba A, Sato T, Kamada N, Kitazume M, Sugita A, Hibi T. Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease. Gastroenterology 137(5), 1736-1745 (2009).
    • (2009) Gastroenterology , vol.137 , Issue.5 , pp. 1736-1745
    • Sakuraba, A.1    Sato, T.2    Kamada, N.3    Kitazume, M.4    Sugita, A.5    Hibi, T.6
  • 41
    • 0023234155 scopus 로고
    • Significance of eosinophil and mast cell counts in rectal mucosa in ulcerative colitis a prospective controlled study
    • Sarin SK, Malhotra V, Sen Gupta S, Karol A, Gaur SK, Anand BS. Significance of eosinophil and mast cell counts in rectal mucosa in ulcerative colitis. A prospective controlled study. Dig. Dis. Sci. 32(4), 363-367 (1987).
    • (1987) Dig. Dis. Sci. , vol.32 , Issue.4 , pp. 363-367
    • Sarin, S.K.1    Malhotra, V.2    Sen Gupta, S.3    Karol, A.4    Gaur, S.K.5    Anand, B.S.6
  • 42
    • 0037310764 scopus 로고    scopus 로고
    • Immunohistochemical study of intestinal eosinophils in inflammatory bowel disease
    • Carvalho AT, Elia CC, De Souza HS et al. Immunohistochemical study of intestinal eosinophils in inflammatory bowel disease. J. Clin. Gastroenterol. 36(2), 120-125 (2003).
    • (2003) J. Clin. Gastroenterol. , vol.36 , Issue.2 , pp. 120-125
    • Carvalho, A.T.1    Elia, C.C.2    De Souza, H.S.3
  • 43
    • 57149085724 scopus 로고    scopus 로고
    • Different regulation of eosinophil activity in Crohn's disease compared with ulcerative colitis
    • Lampinen M, Backman M, Winqvist O et al. Different regulation of eosinophil activity in Crohn's disease compared with ulcerative colitis. J. Leukoc. Biol. 84(6), 1392-1399 (2008).
    • (2008) J. Leukoc. Biol. , vol.84 , Issue.6 , pp. 1392-1399
    • Lampinen, M.1    Backman, M.2    Winqvist, O.3
  • 44
    • 34249333049 scopus 로고    scopus 로고
    • Comparative study of eosinophil chemotaxis adhesion and degranulation in vitro in ulcerative colitis and Crohn's disease
    • Coppi LC, Thomazzi SM, Ayrizono MD et al. Comparative study of eosinophil chemotaxis, adhesion, and degranulation in vitro in ulcerative colitis and Crohn's disease. Inflamm. Bowel Dis. 13 (2), 211-218 (2006).
    • (2006) Inflamm. Bowel Dis. , vol.13 , Issue.2 , pp. 211-218
    • Coppi, L.C.1    Thomazzi, S.M.2    Ayrizono, M.D.3
  • 46
    • 68849110738 scopus 로고    scopus 로고
    • Plexitis as a predictive factor of early postoperative clinical recurrence in Crohn's disease
    • Sokol H, Polin V, Lavergne-Slove A et al. Plexitis as a predictive factor of early postoperative clinical recurrence in Crohn's disease. Gut 58(9), 1218-1225 (2009).
    • (2009) Gut , vol.58 , Issue.9 , pp. 1218-1225
    • Sokol, H.1    Polin, V.2    Lavergne-Slove, A.3
  • 47
    • 77956190936 scopus 로고    scopus 로고
    • + natural killer cells in the intestinal mucosa of patients with Crohn's disease
    • + natural killer cells in the intestinal mucosa of patients with Crohn's disease. Gastroenterology 139(3), 882-892 (2010).
    • (2010) Gastroenterology , vol.139 , Issue.3 , pp. 882-892
    • Takayama, T.1    Kamada, N.2    Chinen, H.3
  • 48
    • 85047690640 scopus 로고    scopus 로고
    • Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
    • Fuss IJ, Heller F, Boirivant M et al. Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J. Clin. Invest. 113(10), 1490-1497 (2004).
    • (2004) J. Clin. Invest. , vol.113 , Issue.10 , pp. 1490-1497
    • Fuss, I.J.1    Heller, F.2    Boirivant, M.3
  • 49
    • 34249788416 scopus 로고    scopus 로고
    • Deficiency of invariant natural killer T cells in coeliac disease
    • Grose RH, Cummins AG, Thompson FM. Deficiency of invariant natural killer T cells in coeliac disease. Gut 56(6), 790-795 (2007).
    • (2007) Gut , vol.56 , Issue.6 , pp. 790-795
    • Grose, R.H.1    Cummins, A.G.2    Thompson, F.M.3
  • 50
    • 77957586284 scopus 로고    scopus 로고
    • Intestinal epithelial cells in inflammatory bowel diseases
    • Roda G, Sartini A, Zambon E et al. Intestinal epithelial cells in inflammatory bowel diseases. World J. Gastroenterol. 16(34), 4264-4271 (2010).
    • (2010) World J. Gastroenterol. , vol.16 , Issue.34 , pp. 4264-4271
    • Roda, G.1    Sartini, A.2    Zambon, E.3
  • 51
  • 52
    • 63849337600 scopus 로고    scopus 로고
    • Mechanism of cytokine modulation of epithelial tight junction barrier
    • Al-Sadi R, Boivin M, Ma T. Mechanism of cytokine modulation of epithelial tight junction barrier. Front Biosci. 14, 2765-2778 (2009).
    • (2009) Front Biosci. , vol.14 , pp. 2765-2778
    • Al-Sadi, R.1    Boivin, M.2    Ma, T.3
  • 53
    • 77958497213 scopus 로고    scopus 로고
    • Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond
    • Cario E. Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond. Curr. Opin. Gastroenterol. 26(6), 583-590 (2010).
    • (2010) Curr. Opin. Gastroenterol. , vol.26 , Issue.6 , pp. 583-590
    • Cario, E.1
  • 54
    • 38549102077 scopus 로고    scopus 로고
    • TNF-mediated inflammatory disease
    • Bradley JR. TNF-mediated inflammatory disease. J. Pathol. 214(2), 149-160 (2008).
    • (2008) J. Pathol. , vol.214 , Issue.2 , pp. 149-160
    • Bradley, J.R.1
  • 55
    • 0027486125 scopus 로고
    • Location of tumour necrosis factor a by immunohistochemistry in chronic inflammatory bowel disease
    • Murch SH, Braegger CP, Walker-Smith JA, Macdonald TT. Location of tumour necrosis factor a by immunohistochemistry in chronic inflammatory bowel disease. Gut 34(12), 1705-1709 (1993).
    • (1993) Gut , vol.34 , Issue.12 , pp. 1705-1709
    • Murch, S.H.1    Braegger, C.P.2    Walker-Smith, J.A.3    Macdonald, T.T.4
  • 56
    • 0025333699 scopus 로고
    • Tumour necrosis factor- A and interferon-g production measured at the single cell level in normal and inflamed human intestine
    • Macdonald TT, Hutchings P, Choy MY, Murch S, Cooke A. Tumour necrosis factor- a and interferon-g production measured at the single cell level in normal and inflamed human intestine. Clin. Exp. Immunol. 81(2), 301-305 (1990).
    • (1990) Clin. Exp. Immunol. , vol.81 , Issue.2 , pp. 301-305
    • Macdonald, T.T.1    Hutchings, P.2    Choy, M.Y.3    Murch, S.4    Cooke, A.5
  • 57
    • 68949144958 scopus 로고    scopus 로고
    • High levels of proinflammatory cytokines but not markers of tissue injury in unaffected intestinal areas from patients with IBD
    • Leon AJ, Gomez E, Garrote JA et al. High levels of proinflammatory cytokines, but not markers of tissue injury, in unaffected intestinal areas from patients with IBD. Mediators Inflamm. 2009, 580450 (2009).
    • (2009) Mediators Inflamm. , vol.2009 , pp. 580450
    • Leon, A.J.1    Gomez, E.2    Garrote, J.A.3
  • 58
    • 0026531017 scopus 로고
    • Tumour necrosis factor a in stool as a marker of intestinal inflammation
    • Braegger CP, Nicholls S, Murch SH, Stephens S, Macdonald TT. Tumour necrosis factor a in stool as a marker of intestinal inflammation. Lancet 339(8785), 89-91 (1992).
    • (1992) Lancet , vol.339 , Issue.8785 , pp. 89-91
    • Braegger, C.P.1    Nicholls, S.2    Murch, S.H.3    Stephens, S.4    Macdonald, T.T.5
  • 59
    • 33746146891 scopus 로고    scopus 로고
    • Interfering with interferons in inflammatory bowel disease
    • Ghosh S, Chaudhary R, Carpani M, Playford R. Interfering with interferons in inflammatory bowel disease. Gut 55(8), 1071-1073 (2006).
    • (2006) Gut , vol.55 , Issue.8 , pp. 1071-1073
    • Ghosh, S.1    Chaudhary, R.2    Carpani, M.3    Playford, R.4
  • 61
    • 0030209985 scopus 로고    scopus 로고
    • + lamina propria LP lymphokine secretion profiles in inflammatory bowel disease crohns disease LP cells manifest increased secretion of IFN-g whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-g, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 157(3), 1261-1270 (1996).
    • (1996) J. Immunol. , vol.157 , Issue.3 , pp. 1261-1270
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3
  • 62
    • 0032916677 scopus 로고    scopus 로고
    • Local and systemic liberation of proinflammatory cytokines in ulcerative colitis
    • Gotteland M, Lopez M, Munoz C et al. Local and systemic liberation of proinflammatory cytokines in ulcerative colitis. Dig. Dis. Sci. 44(4), 830-835 (1999).
    • (1999) Dig. Dis. Sci. , vol.44 , Issue.4 , pp. 830-835
    • Gotteland, M.1    Lopez, M.2    Munoz, C.3
  • 63
    • 33746132472 scopus 로고    scopus 로고
    • A dose escalating placebo controlled double blind single dose and multidose safety and tolerability study of fontolizumab a humanised anti-interferon g antibody in patients with moderate to severe Crohn's disease
    • Reinisch W, Hommes DW, Van Assche G et al. A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon g antibody, in patients with moderate to severe Crohn's disease. Gut 55(8), 1138-1144 (2006).
    • (2006) Gut , vol.55 , Issue.8 , pp. 1138-1144
    • Reinisch, W.1    Hommes, D.W.2    Van Assche, G.3
  • 64
    • 17844396691 scopus 로고    scopus 로고
    • Quantitative measurement of cytokine mRNA in inflammatory bowel disease: Relation to clinical and endoscopic activity and outcome
    • Raddatz D, Bockemuhl M, Ramadori G. Quantitative measurement of cytokine mRNA in inflammatory bowel disease: relation to clinical and endoscopic activity and outcome. Eur. J. Gastroenterol. Hepatol. 17(5), 547-557 (2005).
    • (2005) Eur. J. Gastroenterol. Hepatol. , vol.17 , Issue.5 , pp. 547-557
    • Raddatz, D.1    Bockemuhl, M.2    Ramadori, G.3
  • 67
    • 34548190038 scopus 로고    scopus 로고
    • Il-6 signaling in inflammatory bowel disease: Pathophysiological role and clinical relevance
    • Mudter J, Neurath MF. Il-6 signaling in inflammatory bowel disease: pathophysiological role and clinical relevance. Inflamm. Bowel Dis. 13(8), 1016-1023 (2007).
    • (2007) Inflamm. Bowel Dis. , vol.13 , Issue.8 , pp. 1016-1023
    • Mudter, J.1    Neurath, M.F.2
  • 68
    • 0033835921 scopus 로고    scopus 로고
    • Frequently relapsing Crohns disease is characterized by persistent elevation in interleukin-6 and soluble interleukin-2 receptor serum levels during remission
    • Van Kemseke C, Belaiche J, Louis E. Frequently relapsing Crohn's disease is characterized by persistent elevation in interleukin-6 and soluble interleukin-2 receptor serum levels during remission. Int. J. Colorectal Dis. 15(4), 206-210 (2000).
    • (2000) Int. J. Colorectal Dis. , vol.15 , Issue.4 , pp. 206-210
    • Van Kemseke, C.1    Belaiche, J.2    Louis, E.3
  • 69
    • 11144358366 scopus 로고    scopus 로고
    • A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohns disease
    • Ito H, Takazoe M, Fukuda Y et al. A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology 126(4), 989-996 (2004).
    • (2004) Gastroenterology , vol.126 , Issue.4 , pp. 989-996
    • Ito, H.1    Takazoe, M.2    Fukuda, Y.3
  • 70
    • 70949087383 scopus 로고    scopus 로고
    • Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
    • Glocker EO, Kotlarz D, Boztug K et al. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N. Engl. J. Med. 361(21), 2033-2045 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , Issue.21 , pp. 2033-2045
    • Glocker, E.O.1    Kotlarz, D.2    Boztug, K.3
  • 71
    • 78649746427 scopus 로고    scopus 로고
    • IL-10 family of cytokines
    • Sabat R. IL-10 family of cytokines. Cytokine Growth Factor Rev. 21(5), 315-324 (2010).
    • (2010) Cytokine Growth Factor Rev. , vol.21 , Issue.5 , pp. 315-324
    • Sabat, R.1
  • 72
    • 0141650591 scopus 로고    scopus 로고
    • Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis
    • Melgar S, Yeung MM, Bas A et al. Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis. Clin. Exp. Immunol. 134(1), 127-137 (2003).
    • (2003) Clin. Exp. Immunol. , vol.134 , Issue.1 , pp. 127-137
    • Melgar, S.1    Yeung, M.M.2    Bas, A.3
  • 73
    • 0033782650 scopus 로고    scopus 로고
    • IL-10 secretion and sensitivity in normal human intestine and inflammatory bowel disease
    • Gasche C, Bakos S, Dejaco C, Tillinger W, Zakeri S, Reinisch W. IL-10 secretion and sensitivity in normal human intestine and inflammatory bowel disease. J. Clin. Immunol. 20(5), 362-370 (2000).
    • (2000) J. Clin. Immunol. , vol.20 , Issue.5 , pp. 362-370
    • Gasche, C.1    Bakos, S.2    Dejaco, C.3    Tillinger, W.4    Zakeri, S.5    Reinisch, W.6
  • 74
    • 0034464148 scopus 로고    scopus 로고
    • Safety and efficacy of recombinant human interleukin 10 in chronic active crohns disease crohns disease IL-10 cooperative study group
    • Schreiber S, Fedorak RN, Nielsen OH et al. Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's disease IL-10 cooperative study group. Gastroenterology 119(6), 1461-1472 (2000).
    • (2000) Gastroenterology , vol.119 , Issue.6 , pp. 1461-1472
    • Schreiber, S.1    Fedorak, R.N.2    Nielsen, O.H.3
  • 75
    • 53049091561 scopus 로고    scopus 로고
    • A randomized trial of ustekinumab a human interleukin-12/23 monoclonal antibody in patients with moderate-to-severe crohns disease
    • Sandborn WJ, Feagan BG, Fedorak RN et al. A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 135(4), 1130-1141 (2008).
    • (2008) Gastroenterology , vol.135 , Issue.4 , pp. 1130-1141
    • Sandborn, W.J.1    Feagan, B.G.2    Fedorak, R.N.3
  • 76
    • 0033790206 scopus 로고    scopus 로고
    • Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel disease
    • Vainer B, Nielsen OH, Hendel J, Horn T, Kirman I. Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel disease. Cytokine 12(10), 1531-1536 (2000).
    • (2000) Cytokine , vol.12 , Issue.10 , pp. 1531-1536
    • Vainer, B.1    Nielsen, O.H.2    Hendel, J.3    Horn, T.4    Kirman, I.5
  • 77
    • 23244455992 scopus 로고    scopus 로고
    • Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions apoptosis and cell restitution
    • Heller F, Florian P, Bojarski C et al. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology 129(2), 550-564 (2005).
    • (2005) Gastroenterology , vol.129 , Issue.2 , pp. 550-564
    • Heller, F.1    Florian, P.2    Bojarski, C.3
  • 78
    • 79952532799 scopus 로고    scopus 로고
    • Suppression of inflammation in ulcerative colitis by interferon-b-1a is accompanied by inhibition of IL-13 production
    • Mannon PJ, Hornung RL, Yang Z et al. Suppression of inflammation in ulcerative colitis by interferon-b-1a is accompanied by inhibition of IL-13 production. Gut 60(4), 449-455 (2011).
    • (2011) Gut , vol.60 , Issue.4 , pp. 449-455
    • Mannon, P.J.1    Hornung, R.L.2    Yang, Z.3
  • 79
    • 67650233384 scopus 로고    scopus 로고
    • Interleukin-23 and Th17 cells in the control of gut inflammation
    • Monteleone I, Pallone F, Monteleone G. Interleukin-23 and Th17 cells in the control of gut inflammation. Mediators Inflamm. 2009, 297645 (2009).
    • (2009) Mediators Inflamm. , vol.2009 , pp. 297645
    • Monteleone, I.1    Pallone, F.2    Monteleone, G.3
  • 80
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 in inflammatory bowel disease
    • Fujino S, Andoh A, Bamba S et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52(1), 65-70 (2003).
    • (2003) Gut , vol.52 , Issue.1 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3
  • 81
    • 78649936808 scopus 로고    scopus 로고
    • Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease
    • Bogaert S, Laukens D, Peeters H et al. Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease. BMC Immunol. 11, 61 (2010).
    • (2010) BMC Immunol. , vol.11 , pp. 61
    • Bogaert, S.1    Laukens, D.2    Peeters, H.3
  • 82
    • 72949086194 scopus 로고    scopus 로고
    • Translational mini-review series on Th17 cells: Are T helper 17 cells really pathogenic in autoimmunity
    • Koenders MI, Van Den Berg WB. Translational mini-review series on Th17 cells: are T helper 17 cells really pathogenic in autoimmunity? Clin. Exp. Immunol. 159(2), 131-136 (2009).
    • (2009) Clin. Exp. Immunol. , vol.159 , Issue.2 , pp. 131-136
    • Koenders, M.I.1    Van Den Berg, W.B.2
  • 83
    • 71349086708 scopus 로고    scopus 로고
    • From IL-15 to IL-33: The never-ending list of new players in inflammation is it time to forget the humble aspirin and move ahead
    • D'acquisto F, Maione F, Pederzoli-Ribeil M. From IL-15 to IL-33: the never-ending list of new players in inflammation. Is it time to forget the humble aspirin and move ahead? Biochem. Pharmacol. 79(4), 525-534 (2010).
    • (2010) Biochem. Pharmacol. , vol.79 , Issue.4 , pp. 525-534
    • D'acquisto, F.1    Maione, F.2    Pederzoli-Ribeil, M.3
  • 84
    • 43549099743 scopus 로고    scopus 로고
    • The Interleukin-23/ Interleukin-17 axis in intestinal inflammation
    • Maloy KJ. The Interleukin-23/ Interleukin-17 axis in intestinal inflammation. J. Intern. Med. 263(6), 584-590 (2008).
    • (2008) J. Intern. Med. , vol.263 , Issue.6 , pp. 584-590
    • Maloy, K.J.1
  • 85
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314(5804), 1461-1463 (2006).
    • (2006) Science , vol.314 , Issue.5804 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3
  • 86
    • 79952378686 scopus 로고    scopus 로고
    • Immunology: Context is key in the gut
    • Maynard CL, Weaver CT. Immunology: context is key in the gut. Nature 471(7337), 169-170 (2011).
    • (2011) Nature , vol.471 , Issue.7337 , pp. 169-170
    • Maynard, C.L.1    Weaver, C.T.2
  • 87
    • 35148833220 scopus 로고    scopus 로고
    • Tissue levels of tumor necrosis factor-a correlates with grade of inflammation in untreated ulcerative colitis
    • Olsen T, Goll R, Cui G et al. Tissue levels of tumor necrosis factor-a correlates with grade of inflammation in untreated ulcerative colitis. Scand. J. Gastroenterol. 42(11), 1312-1320 (2007).
    • (2007) Scand. J. Gastroenterol. , vol.42 , Issue.11 , pp. 1312-1320
    • Olsen, T.1    Goll, R.2    Cui, G.3
  • 88
    • 66149152303 scopus 로고    scopus 로고
    • Quantitive cytokine mRNA expression profiles in the colonic mucosa of patients with steroid naive ulcerative colitis during active and quiescent disease
    • Matsuda R, Koide T, Tokoro C et al. Quantitive cytokine mRNA expression profiles in the colonic mucosa of patients with steroid naive ulcerative colitis during active and quiescent disease. Inflamm. Bowel Dis. 15(3), 328-334 (2009).
    • (2009) Inflamm. Bowel Dis. , vol.15 , Issue.3 , pp. 328-334
    • Matsuda, R.1    Koide, T.2    Tokoro, C.3
  • 89
    • 37349050665 scopus 로고    scopus 로고
    • Increased expression and activation of IL-12-induced Stat4 signaling in the mucosa of ulcerative colitis patients
    • Pang YH, Zheng CQ, Yang XZ, Zhang WJ. Increased expression and activation of IL-12-induced Stat4 signaling in the mucosa of ulcerative colitis patients. Cell Immunol. 248(2), 115-120 (2007).
    • (2007) Cell Immunol. , vol.248 , Issue.2 , pp. 115-120
    • Pang, Y.H.1    Zheng, C.Q.2    Yang, X.Z.3    Zhang, W.J.4
  • 90
    • 0033199084 scopus 로고    scopus 로고
    • Characterization of cytokine expression in the rectal mucosa of ulcerative colitis: Correlation with disease activity
    • Inoue S, Matsumoto T, Iida M et al. Characterization of cytokine expression in the rectal mucosa of ulcerative colitis: correlation with disease activity. Am. J. Gastroenterol. 94(9), 2441-2446 (1999).
    • (1999) Am. J. Gastroenterol. , vol.94 , Issue.9 , pp. 2441-2446
    • Inoue, S.1    Matsumoto, T.2    Iida, M.3
  • 91
    • 75749150514 scopus 로고    scopus 로고
    • Late crohns disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients
    • Veny M, Esteller M, Ricart E, Pique JM, Panes J, Salas A. Late Crohn's disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients. Aliment. Pharmacol. Ther. 31(5), 561-572 (2009).
    • (2009) Aliment. Pharmacol. Ther. , vol.31 , Issue.5 , pp. 561-572
    • Veny, M.1    Esteller, M.2    Ricart, E.3    Pique, J.M.4    Panes, J.5    Salas, A.6
  • 92
    • 59749093262 scopus 로고    scopus 로고
    • Cytokine network in rectal mucosa in perianal crohns disease: Relations with inflammatory parameters and need for surgery
    • Ruffolo C, Scarpa M, Faggian D et al. Cytokine network in rectal mucosa in perianal Crohn's disease: relations with inflammatory parameters and need for surgery. Inflamm. Bowel Dis. 14(10), 1406-1412 (2008).
    • (2008) Inflamm. Bowel Dis. , vol.14 , Issue.10 , pp. 1406-1412
    • Ruffolo, C.1    Scarpa, M.2    Faggian, D.3
  • 93
    • 42449084096 scopus 로고    scopus 로고
    • Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease IBD: Upregulated colonic IL-17F expression in active crohns disease and analysis of the IL17F p.His161Arg polymorphism in IBD
    • Seiderer J, Elben I, Diegelmann J et al. Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm. Bowel Dis. 14(4), 437-445 (2008).
    • (2008) Inflamm. Bowel Dis. , vol.14 , Issue.4 , pp. 437-445
    • Seiderer, J.1    Elben, I.2    Diegelmann, J.3
  • 94
    • 77952222918 scopus 로고    scopus 로고
    • The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease
    • Sugihara T, Kobori A, Imaeda H et al. The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease. Clin. Exp. Immunol. 160(3), 386-393 (2010).
    • (2010) Clin. Exp. Immunol. , vol.160 , Issue.3 , pp. 386-393
    • Sugihara, T.1    Kobori, A.2    Imaeda, H.3
  • 95
    • 13944281011 scopus 로고    scopus 로고
    • Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
    • Schmidt C, Giese T, Ludwig B et al. Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm. Bowel Dis. 11(1), 16-23 (2005).
    • (2005) Inflamm. Bowel Dis. , vol.11 , Issue.1 , pp. 16-23
    • Schmidt, C.1    Giese, T.2    Ludwig, B.3
  • 96
    • 0034956578 scopus 로고    scopus 로고
    • Tumor necrosis factor-a in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno- PCR
    • Komatsu M, Kobayashi D, Saito K et al. Tumor necrosis factor-a in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno- PCR. Clin. Chem. 47(7), 1297-1301 (2001).
    • (2001) Clin. Chem. , vol.47 , Issue.7 , pp. 1297-1301
    • Komatsu, M.1    Kobayashi, D.2    Saito, K.3
  • 97
    • 57449087458 scopus 로고    scopus 로고
    • Patients with inflammatory bowel disease may have a transforming growth factor-b- interleukin IL-2 or IL-10-deficient state induced by intrinsic neutralizing antibodies
    • Ebert EC, Panja A, Das KM et al. Patients with inflammatory bowel disease may have a transforming growth factor-b-, interleukin (IL)-2 or IL-10-deficient state induced by intrinsic neutralizing antibodies. Clin. Exp. Immunol. 155(1), 65-71 (2009).
    • (2009) Clin. Exp. Immunol. , vol.155 , Issue.1 , pp. 65-71
    • Ebert, E.C.1    Panja, A.2    Das, K.M.3
  • 98
    • 1842456977 scopus 로고    scopus 로고
    • Relationships between serum IGF-1 IGFBP-2 interleukin-1b and interleukin-6 in inflammatory bowel disease
    • Street ME, De'Angelis G, Camacho- Hubner C et al. Relationships between serum IGF-1, IGFBP-2, interleukin-1b and interleukin-6 in inflammatory bowel disease. Horm. Res. 61(4), 159-164 (2004).
    • (2004) Horm. Res. , vol.61 , Issue.4 , pp. 159-164
    • Street, M.E.1    De'Angelis, G.2    Camacho- Hubner, C.3
  • 99
    • 34248206040 scopus 로고    scopus 로고
    • Interleukin-10 in the pathophysiology of inflammatory bowel disease: Increased serum concentrations during the recovery phase
    • Mitsuyama K, Tomiyasu N, Takaki K et al. Interleukin-10 in the pathophysiology of inflammatory bowel disease: increased serum concentrations during the recovery phase. Mediators Inflamm. 2006(6), 26875 (2006).
    • (2006) Mediators Inflamm. , vol.2006 , Issue.6 , pp. 26875
    • Mitsuyama, K.1    Tomiyasu, N.2    Takaki, K.3
  • 100
  • 102
    • 78650883772 scopus 로고    scopus 로고
    • Expression of cytokines in the gingival crevicular fluid and serum from patients with inflammatory bowel disease and untreated chronic periodontitis
    • Figueredo CM, Brito F, Barros FC et al. Expression of cytokines in the gingival crevicular fluid and serum from patients with inflammatory bowel disease and untreated chronic periodontitis. J. Periodontal Res. 46(1), 141-146 (2011).
    • (2011) J. Periodontal Res. , vol.46 , Issue.1 , pp. 141-146
    • Figueredo, C.M.1    Brito, F.2    Barros, F.C.3


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