Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13

Journal of Gastroenterology

Volumn 47, Issue 11, 2012, Pages 1198-1211

  Camelo, Ana ^a   Barlow, Jillian L ^a   Drynan, Lesley F ^a   Neill, Daniel R ^b   Ballantyne, Sarah J ^a   Wong, See Heng ^c   Pannell, Richard ^a   Gao, Wei ^d   Wrigley, Keely ^d   Sprenkle, Justin ^d   Andrew N J McKenzie, ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c MEDIMMUNE LTD   (United Kingdom)

^d CENTOCOR INC   (United States)

Author keywords

IL 13; IL 25; Inflammatory bowel disease; Nuocytes

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 25; NEUTRALIZING ANTIBODY; OXAZOLONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; COLON ULCER; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE MODEL; EOSINOPHILIA; FEMALE; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; LAMINA PROPRIA; LEUKOCYTE; MESENTERY LYMPH NODE; MOUSE; MUCOSA INFLAMMATION; NATURAL KILLER T CELL; NONHUMAN; NUOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE CULTURE; ULCERATIVE COLITIS; WEIGHT REDUCTION;

EID: 84872277296     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-012-0591-2     Document Type: Article

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