Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity

Nature Medicine

Volumn 19, Issue 10, 2013, Pages 1297-1304

  Albacker, Lee A ^a   Chaudhary, Vinod ^b   Chang, Ya Jen ^a,c   Kim, Hye Young ^a   Chuang, Ya Ting ^a   Pichavant, Muriel ^a   Dekruyff, Rosemarie H ^a   Savage, Paul B ^b   Umetsu, Dale T ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b Brigham Young University   (United States)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ASPERAMIDE B; CD1D ANTIGEN; DECTIN 1; GAMMA INTERFERON; GLYCOSPHINGOLIPID; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 4; INVARIANT T LYMPHOCYTE RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; PATTERN RECOGNITION RECEPTOR; PLANT EXTRACT; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG; 1-O-BETA-D-GLUCOPYRANOSYL-(2S,2'R,3R,3'E,4E,8E)-N-(2'-HYDROXY-3'-HEXADECENOYL)-9-METHYL-4,8-ICOSADIEN-1,3-DIOL; SPHINGOLIPID;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; ASPERGILLUS FUMIGATUS; ASTHMA; CELL ACTIVATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG INDUCED DISEASE; FLOW CYTOMETRY; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INVARIANT NATURAL KILLER T CELL; LUNG LAVAGE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; WILD TYPE; ANIMAL; BAGG ALBINO MOUSE; BRONCHUS HYPERREACTIVITY; CHEMICALLY INDUCED; CHEMISTRY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; TOXICITY;

ASPERGILLUS FUMIGATUS; FUNGI;

ANIMALS; ASPERGILLUS FUMIGATUS; BRONCHIAL HYPERREACTIVITY; GLYCOSPHINGOLIPIDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; NATURAL KILLER T-CELLS; SPHINGOLIPIDS;

EID: 84886262448     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3321     Document Type: Article

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