Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression

Oncology Reports

Volumn 31, Issue 6, 2014, Pages 2769-2775

  Zhao, Bing ^a   Li, Xiaomeng ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

Akt; Altholactone; Apoptosis; Bcl 2 protein; Bladder cancer; MAPK p38

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; GONIOTHALENOL; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; FURAN DERIVATIVE; PYRONE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CANCER GROWTH; CELL VIABILITY; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; GONIOTHALAMUS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BLADDER TUMOR; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ACETYLCYSTEINE; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; FURANS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOCHONDRIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRONES; REACTIVE OXYGEN SPECIES; URINARY BLADDER NEOPLASMS;

EID: 84902160078     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3126     Document Type: Article

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