Induction of mitochondria-mediated apoptosis in human gastric adenocarcinoma SGC-7901 cells by kuraridin and nor-kurarinone isolated from sophora flavescens

Asian Pacific Journal of Cancer Prevention

Volumn 12, Issue 10, 2011, Pages 2499-2504

  Rasul, Azhar ^a   Yu, Bo ^b   Yang, Long Fei ^a   Ali, Muhammad ^c   Khan, Muhammad ^a   Ma, Tonghui ^a,b   Yang, Hong ^b  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b LIAONING NORMAL UNIVERSITY   (China)

^c BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

Author keywords

Apoptosis; HPLC; Kuraridin; Kurarinone; Nor; Sophora flavescens

Indexed keywords

EID: 84863238350     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Amin AR, Kucuk O, Khuri FR, et al (2009). Perspectives for cancer prevention with natural compounds. J Clin Oncol, 27, 2712-25.
2. Chan WH (2007). Citrinin induces apoptosis via a mitochondria-dependent pathway and inhibition of survival signals in embryonic stem cells, and causes developmental injury in blastocysts. Biochem J, 404, 317-26.
3. Chen CY, Liu TZ, Liu YW, et al (2007). 6-Shogaol (alkanone from ginger) induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism. J Agric Food Chem, 55, 948-54.
4. Chung MY, Rho MC, Ko JS, et al (2004). In vitro inhibition of diacylglycerol acyltransferase by prenylflavonoids from Sophora flavescens. Planta Med, 70, 258-60.
5. Cohen P (1997). The search for physiological substrates of MAP and SAP kinases in mammalian cells. Trends Cell Biol, 7, 353-61.
6. Cragg GM, Newman DJ (2005). Plants as a source of anti-cancer agents. J Ethnopharmacol, 100, 72-9.
7. Ding PL, Hou AJ, Chen DF (2005). Three new isoprenylated flavonoids from the roots of Sophora flavescens. J Asian Nat Prod Res, 7, 237-43.
8. Ding Y, Tian RH, Kinjo J, et al (1992). Three new oleanene glycosides from Sophora flavescens. Chem Pharm Bull, 40, 2990-4.
9. Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-917.
10. Grana X, Reddy EP (1995). Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene, 11, 211-9.
11. Hernandez BY, Green MD, Cassel KD, et al (2010). Preview of Hawaii Cancer Facts and Figures 2010. Hawaii Med J, 69, 223-4.
12. Kang N, Zhang JH, Qiu F, et al (2010). Induction of G(2)/M phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells. J Nat Prod, 73, 1058-63.
13. Kang SS, Kim JS, Son KH, et al (2000a). A new prenylated flavanone from the roots of Sophora flavescens. Fitoterapia, 71, 511-5.
14. Kang TH, Jeong SJ, Ko WG, et al (2000b). Cytotoxic lavandulyl flavanones from Sophora flavescens. J Nat Prod, 63, 680-1.
15. Kastan MB, Canman CE, Leonard CJ (1995). P53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev, 14, 3-15.
16. Kim JH, Ryu YB, Kang NS, et al (2006). Glycosidase inhibitory flavonoids from Sophora flavescens. Biol Pharm Bull, 29, 302-5.
17. Kim SJ, Son KH, Chang HW, et al (2003). Tyrosinase inhibitory prenylated flavonoids from Sophora flavescens. Biol Pharm Bull, 26, 1348-50.
18. Kluck RM, Bossy-Wetzel E, Green DR, et al (1997). The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science, 275, 1132-6.
19. Kuroyanagi M, Arakawa T, Hirayama Y, et al (1999). Antibacterial and antiandrogen flavonoids from Sophora flavescens. J Nat Prod, 62, 1595-9.
20. Kyogoku K, Hatayama K, Komatsu M (1973). Constituents of Chinese crude drug "Kushen" (the root of Sophora flavescens Ait.). Isolation of five new flavonoids and formononetin. Chem Pharm Bull (Tokyo), 21, 2733-8.
21. Lee JH, Baek NI, Kim SH, et al (2007). A new cytotoxic prenylated chalcone from Sophora flavescens. Arch Pharm Res, 30, 408-11.
22. Liu D, Xin X, Su DH, et al (2010). Two new lavandulyl flavonoids from Sophora flavescens. Nat Prod Commun, 5, 1889-91.
23. Mantena SK, Sharma SD, Katiyar SK (2006). Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol Cancer Ther, 5, 296-308.
24. Oh I, Yang WY, Chung SC, et al (2011). In vitro sortase a inhibitory and antimicrobial activity of flavonoids isolated from the roots of Sophora flavescens. Arch Pharm Res, 34, 217-22.
25. Okuda S, Murakoshi I, Kamata H, et al (1965). Studies on lupin alkaloids. I. The minor alkaloids of Japanese Sophora flavescens. Chem Pharm Bull, 13, 482-7.
26. Parkin DM (2001). Global cancer statistics in the year 2000. Lancet Oncol, 2, 533-43.
27. Pavletich NP (1999). Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J Mol Biol, 287, 821-8.
28. Rasul A, Khan M, Yu B, et al (2011). Xanthoxyletin, a coumarin induces S phase arrest and apoptosis in human gastric adenocarcinoma SGC-7901 cells. Asian Pac J Cancer Prev, 12, 1219-23.
29. Reed JC (1998). Bcl-2 family proteins. Oncogene, 17, 3225-36.
30. Sekine T, Saito K, Minami R, et al (1993). A new lupin alkaloid, (-)-leontalbinine N-oxide, in Sophora flavescens var. angustifolia seeds and its synthesis by biomimetic transformation from (+)-matrine N-oxide. Yakugaku Zasshi, 113, 53-62 (in Japanese).
31. Shawi AA, Rasul A, Khan M, et al (2011). Eupatilin: A flavonoid compound isolated from the artemisia plant, induces apoptosis and G2/M phase cell cycle arrest in human melanoma A375 cells. Afr. J. pharm. pharmaco, 5, 582-88.
32. Shen CC, Lin TW, Huang YL, et al (2006). Phenolic constituents of the roots of Sophora flavescens. J Nat Prod, 69, 1237-40.
33. Shimizu S, Narita M, Tsujimoto Y (1999). Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature, 399, 483-7.
34. Slater AF, Stefan C, Nobel I, et al (1995). Signalling mechanisms and oxidative stress in apoptosis. Toxicol Lett, 82-83, 149-53.
35. Sohn HY, Son KH, Kwon CS, et al (2004). Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis Nakai. Phytomedicine, 11, 666-72.
36. Son JK, Park JS, Kim JA, et al (2003). Prenylated flavonoids from the roots of Sophora flavescens with tyrosinase inhibitory activity. Planta Med, 69, 559-61.
37. Song JZ, Xu HX, Tian SJ, et al (1999). Determination of quinolizidine alkaloids in traditional Chinese herbal drugs by nonaqueous capillary electrophoresis. J Chromatogr A, 857, 303-11.
38. Srivastava JK, Gupta S (2006). Tocotrienol-rich fraction of palm oil induces cell cycle arrest and apoptosis selectively in human prostate cancer cells. Biochem Biophys Res Commun, 346, 447-53.
39. Strathmann J, Klimo K, Sauer SW, et al (2010). Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism. FASEB J, 24, 2938-50.
40. Vercesi AE, Kowaltowski AJ, Grijalba MT, et al (1997). The role of reactive oxygen species in mitochondrial permeability transition. Biosci Rep, 17, 43-52.
41. Wan XS, Zhou Z, Kennedy AR (2003). Adaptation of the dichlorofluorescein assay for detection of radiation-induced oxidative stress in cultured cells. Radiat Res, 160, 622-30.
42. Wang X (2001). The expanding role of mitochondria in apoptosis. Genes Dev, 15, 2922-33.
43. Yang L, Parkin DM, Ferlay J, et al (2005). Estimates of cancer incidence in China for 2000 and projections for 2005. Cancer Epidemiol Biomarkers Prev, 14, 243-50.
44. Zhu YP (1998) Chinese Materia Medica Harwood Academic Publishers Amsterdam, 149-55