Downregulation of VEGF-A, STAT5 and AKT in acute myeloid leukemia blasts of patients treated with SU5416

Leukemia and Lymphoma

Volumn 47, Issue 12, 2006, Pages 2601-2609

  Loges, Sonja ^a   Tinnefeld, Heike ^a   Metzner, Anja ^a   Jücker, Manfred ^a   Butzal, Martin ^a   Bruweleit, Melanie ^a   Fischer, Uta ^a   Draab, Elena ^a   Schuch, Gunter ^a   O' Farrel, Anne Marie ^b   Hossfeld, Dieter Kurt ^a   Bokemeyer, Carsten ^a   Fiedler, Walter ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b Phenomix Corporation   (United States)

Author keywords

AML; Angiogenesis; Anti angiogenetic treatment; Signal transduction; Small molecule tyrosine kinase inhibitor

Indexed keywords

DEXAMETHASONE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYUREA; MESSENGER RNA; PROTEIN KINASE B; SEMAXANIB; STAT5 PROTEIN; VASCULOTROPIN A;

ACUTE GRANULOCYTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG RESPONSE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MULTICENTER STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; CELL LINE, TUMOR; CELL SEPARATION; DISEASE PROGRESSION; DNA PRIMERS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDOLES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PYRROLES; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33845582907     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190600948253     Document Type: Article

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