Isoalantolactone, a sesquiterpene lactone, induces apoptosis in SGC-7901 cells via mitochondrial and phosphatidylinositol 3-kinase/Akt signaling pathways

Archives of Pharmacal Research

Volumn 36, Issue 10, 2013, Pages 1262-1269

  Rasul, Azhar ^a   Khan, Muhammad ^a   Yu, Bo ^b   Ali, Muhammad ^c   Bo, Yang Jing ^a   Yang, Hong ^b   Ma, Tonghui ^a,b  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b LIAONING NORMAL UNIVERSITY   (China)

^c BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

Author keywords

Apoptosis; Isoalantolactone; PI3K Akt pathway; Sesquiterpene lactone; SGC 7901 cells

Indexed keywords

CASPASE; CYCLIN B1; ISOALANTOLACTONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIDIUM IODIDE; PROTEIN KINASE B; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VIVO STUDY; MEMBRANE POTENTIAL; MITOCHONDRIAL DYNAMICS; S PHASE CELL CYCLE CHECKPOINT; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA;

APOPTOSIS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIN B1; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SESQUITERPENES; SIGNAL TRANSDUCTION;

EID: 84885952969     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0217-0     Document Type: Article

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