-
1
-
-
22044446238
-
The ubiquitin-proteasome system in Creutzfeldt-Jakob and Alzheimer disease: Intracellular redistribution of components correlates with neuronal vulnerability
-
1:CAS:528:DC%2BD2MXmt1aqtLY%3D 16023585 10.1016/j.nbd.2005.01.015
-
Adori, C., Kovács, G. G., Low, P., et al. (2005). The ubiquitin-proteasome system in Creutzfeldt-Jakob and Alzheimer disease: Intracellular redistribution of components correlates with neuronal vulnerability. Neurobiol Dis., 19, 427-435.
-
(2005)
Neurobiol Dis.
, vol.19
, pp. 427-435
-
-
Adori, C.1
Kovács, G.G.2
Low, P.3
-
2
-
-
0028856460
-
An English translation of Alzheimer's 1907 paper, Uber eine eigenartige Erkankung der Hirnrinde
-
(New York, NY)
-
Alzheimer A., Stelzmann R.A., Schnitzlein H.N., Murtagh F.R. (1995). An English translation of Alzheimer's 1907 paper, Uber eine eigenartige Erkankung der Hirnrinde. Clin Anat (New York, NY) 8: 429-431.
-
(1995)
Clin Anat
, vol.8
, pp. 429-431
-
-
Alzheimer, A.1
Stelzmann, R.A.2
Schnitzlein, H.N.3
Murtagh, F.R.4
-
3
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
1:CAS:528:DC%2BD28Xht1Sgtb3I 17086191 10.1038/nature05354
-
Baur, J. A., Pearson, K. J., Price, N. L., et al. (2006). Resveratrol improves health and survival of mice on a high-calorie diet. Nature, 444, 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
-
4
-
-
45549098657
-
SirT1 regulates energy metabolism and response to caloric restriction in mice
-
2258149 18335035 10.1371/journal.pone.0001759
-
Boily, G., Seifert, E. L., Bevilacqua, L., et al. (2008). SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One, 3, e1759.
-
(2008)
PLoS One
, vol.3
, pp. 1759
-
-
Boily, G.1
Seifert, E.L.2
Bevilacqua, L.3
-
5
-
-
77957955081
-
High-density genomewide linkage analysis of exceptional human longevity identifies multiple novel loci
-
2930849 20824210 10.1371/journal.pone.0012432
-
Boyden, S. E., & Kunkel, L. M. (2010). High-density genomewide linkage analysis of exceptional human longevity identifies multiple novel loci. PLoS One, 5, e12432.
-
(2010)
PLoS One
, vol.5
, pp. 12432
-
-
Boyden, S.E.1
Kunkel, L.M.2
-
6
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
1:STN:280:DyaK387gtFOiug%3D%3D 10.1007/BF00308809
-
Braak, H., & Braak, E. (1991). Neuropathological stageing of Alzheimer-related changes. Acta Neuropatholog, 82, 239-259.
-
(1991)
Acta Neuropatholog
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
7
-
-
84887020906
-
Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3
-
10.1016/j.mito.2013.04.002 23583953
-
Brenmoehl, J., & Hoeflich, A. (2013). Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3. Mitochondrion. doi: 10.1016/j.mito.2013. 04.002.
-
(2013)
Mitochondrion
-
-
Brenmoehl, J.1
Hoeflich, A.2
-
8
-
-
84871650203
-
Neuroinflammation and neurodegeneration in overnutrition-induced diseases
-
1:CAS:528:DC%2BC38XhvVylsr7K 10.1016/j.tem.2012.11.003
-
Cai, D. (2013). Neuroinflammation and neurodegeneration in overnutrition-induced diseases. Trends Endocrinol Metabol TEM, 24, 40-47.
-
(2013)
Trends Endocrinol Metabol TEM
, vol.24
, pp. 40-47
-
-
Cai, D.1
-
9
-
-
69849107217
-
Caloric restriction, SIRT1 and longevity
-
10.1016/j.tem.2009.03.008
-
Cantó, C., & Auwerx, J. (2009). Caloric restriction, SIRT1 and longevity. Trends Endocrinol Metabol TEM, 20, 325-331.
-
(2009)
Trends Endocrinol Metabol TEM
, vol.20
, pp. 325-331
-
-
Cantó, C.1
Auwerx, J.2
-
10
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
-
1:CAS:528:DC%2BD2MXht1Gjs7vF 16183991 10.1074/jbc.M509329200
-
Chen, J., Zhou, Y., Mueller-Steiner, S., et al. (2005). SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J Biol Chem, 280, 40364-40374.
-
(2005)
J Biol Chem
, vol.280
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
-
11
-
-
84874485938
-
Genealogy of an ancient protein family: The Sirtuins, a family of disordered members
-
1:CAS:528:DC%2BC3sXmt1GksLc%3D 3599600 23497088 10.1186/1471-2148-13-60
-
Costantini, S., Sharma, A., Raucci, R., et al. (2013). Genealogy of an ancient protein family: The Sirtuins, a family of disordered members. BMC Evol Biol, 13, 60.
-
(2013)
BMC Evol Biol
, vol.13
, pp. 60
-
-
Costantini, S.1
Sharma, A.2
Raucci, R.3
-
12
-
-
77958488312
-
SIRT1 activation by small molecules: Kinetic and biophysical evidence for direct interaction of enzyme and activator
-
1:CAS:528:DC%2BC3cXht12nu77E 2963390 20702418 10.1074/jbc.M110.133892
-
Dai, H., Kustigian, L., Carney, D., et al. (2010). SIRT1 activation by small molecules: Kinetic and biophysical evidence for direct interaction of enzyme and activator. J Biol Chem, 285, 32695-32703.
-
(2010)
J Biol Chem
, vol.285
, pp. 32695-32703
-
-
Dai, H.1
Kustigian, L.2
Carney, D.3
-
13
-
-
0034779064
-
Sex-specific longevity associations defined by Tyrosine Hydroxylase-Insulin-Insulin Growth Factor 2 haplotypes on the 11p15.5 chromosomal region
-
11672987 10.1016/S0531-5565(01)00146-2
-
De Luca, M., Rose, G., Bonafè, M., et al. (2001). Sex-specific longevity associations defined by Tyrosine Hydroxylase-Insulin-Insulin Growth Factor 2 haplotypes on the 11p15.5 chromosomal region. Exp Gerontol, 36, 1663-1671.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1663-1671
-
-
De Luca, M.1
Rose, G.2
Bonafè, M.3
-
14
-
-
84866505685
-
A simple protocol for the subcellular fractionation of skeletal muscle cells and tissue
-
10.1186/1756-0500-5-513
-
Dimauro, I., Pearson, T., Caporossi, D., & Jackson, M. J. (2012). A simple protocol for the subcellular fractionation of skeletal muscle cells and tissue. BMC Res Notes, 2012(5), 513.
-
(2012)
BMC Res Notes
, vol.2012
, Issue.5
, pp. 513
-
-
Dimauro, I.1
Pearson, T.2
Caporossi, D.3
Jackson, M.J.4
-
15
-
-
77955046461
-
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
-
1:CAS:528:DC%2BC3cXpsVahsrw%3D 2911635 20655472 10.1016/j.cell.2010.06. 020
-
Donmez, G., Wang, D., Cohen, D. E., & Guarente, L. (2010). SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell, 142, 320-332.
-
(2010)
Cell
, vol.142
, pp. 320-332
-
-
Donmez, G.1
Wang, D.2
Cohen, D.E.3
Guarente, L.4
-
16
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
1:CAS:528:DC%2BC3MXhsVagtrnI 3217313 22076378 10.1126/science.1207861
-
Du, J., Zhou, Y., Su, X., et al. (2011). Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science, 334, 806-809.
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
-
17
-
-
67349143998
-
Classification and basic pathology of Alzheimer disease
-
1:CAS:528:DC%2BD1MXmt1ahu70%3D 19381658 10.1007/s00401-009-0532-1
-
Duyckaerts, C., Delatour, B., & Potier, M. (2009). Classification and basic pathology of Alzheimer disease. Acta Neuropathol, 118, 5-36.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 5-36
-
-
Duyckaerts, C.1
Delatour, B.2
Potier, M.3
-
18
-
-
41549136422
-
Paths of convergence: Sirtuins in aging and neurodegeneration
-
1:CAS:528:DC%2BD1cXltVOisrs%3D 18400158 10.1016/j.neuron.2008.03.015
-
Gan, L., & Mucke, L. (2008). Paths of convergence: Sirtuins in aging and neurodegeneration. Neuron, 58, 10-14.
-
(2008)
Neuron
, vol.58
, pp. 10-14
-
-
Gan, L.1
Mucke, L.2
-
19
-
-
80054968456
-
SIRT1 and SIRT5 activity expression and behavioral responses to calorie restriction
-
1:CAS:528:DC%2BC3MXhtlGgurjM 21826711 10.1002/jcb.23315
-
Geng, Y.-Q., Li, T-. T., Liu, X.-Y., et al. (2011). SIRT1 and SIRT5 activity expression and behavioral responses to calorie restriction. J Cell Biochem, 112, 3755-3761.
-
(2011)
J Cell Biochem
, vol.112
, pp. 3755-3761
-
-
Geng, Y.-Q.1
Li, T.-T.2
Liu, X.-Y.3
-
20
-
-
78650624567
-
Brain molecular aging, promotion of neurological disease and modulation by sirtuin 5 longevity gene polymorphism
-
1:CAS:528:DC%2BC3MXovFag 3014380 20887790 10.1016/j.nbd.2010.09.016
-
Glorioso, C., Oh, S., Douillard, G. G., & Sibille, E. (2011). Brain molecular aging, promotion of neurological disease and modulation by sirtuin 5 longevity gene polymorphism. Neurobiol Dis, 41, 279-290.
-
(2011)
Neurobiol Dis
, vol.41
, pp. 279-290
-
-
Glorioso, C.1
Oh, S.2
Douillard, G.G.3
Sibille, E.4
-
21
-
-
33750705653
-
A century of Alzheimer's disease
-
1:CAS:528:DC%2BD28XhtFKit73K 17082447 10.1126/science.1132814
-
Goedert, M., & Spillantini, M. G. (2006). A century of Alzheimer's disease. Science, 314, 777-781.
-
(2006)
Science
, vol.314
, pp. 777-781
-
-
Goedert, M.1
Spillantini, M.G.2
-
22
-
-
84874594425
-
The sirtuin family's role in aging and age-associated pathologies
-
1:CAS:528:DC%2BC3sXjvVyhsLo%3D 3582122 23454760 10.1172/JCI64094
-
Hall, J. A., Dominy, J. E., Lee, Y., & Puigserver, P. (2013). The sirtuin family's role in aging and age-associated pathologies. J Clin Invest, 123, 973-979.
-
(2013)
J Clin Invest
, vol.123
, pp. 973-979
-
-
Hall, J.A.1
Dominy, J.E.2
Lee, Y.3
Puigserver, P.4
-
23
-
-
84883451566
-
Maintaining good hearing: Calorie restriction, Sirt3, and glutathione
-
10.1016/j.exger.2013.02.014
-
Han, C., & Someya, S. (2013). Maintaining good hearing: Calorie restriction, Sirt3, and glutathione. Exp Gerontol. doi: 10.1016/j.exger.2013.02. 014.
-
(2013)
Exp Gerontol
-
-
Han, C.1
Someya, S.2
-
24
-
-
84878717391
-
Sirtuin deacetylases in neurodegenerative diseases of aging
-
1:CAS:528:DC%2BC3sXptVWjur4%3D 3674397 23689277 10.1038/cr.2013.70
-
Herskovits, A. Z., & Guarente, L. (2013). Sirtuin deacetylases in neurodegenerative diseases of aging. Cell Res, 23, 746-758.
-
(2013)
Cell Res
, vol.23
, pp. 746-758
-
-
Herskovits, A.Z.1
Guarente, L.2
-
25
-
-
55749095213
-
Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
-
1:CAS:528:DC%2BD1cXht1GisbfI 2563076 18829436 10.1073/pnas.0800612105
-
Hisahara, S., Chiba, S., Matsumoto, H., et al. (2008). Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. Proc Natl Acad Sci USA, 105, 15599-15604.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15599-15604
-
-
Hisahara, S.1
Chiba, S.2
Matsumoto, H.3
-
26
-
-
78649351587
-
Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis
-
20737479 10.1002/glia.21054
-
Höftberger, R., Fink, S., Aboul-Enein, F., et al. (2010). Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis. Glia, 58, 1847-1857.
-
(2010)
Glia
, vol.58
, pp. 1847-1857
-
-
Höftberger, R.1
Fink, S.2
Aboul-Enein, F.3
-
27
-
-
84858797950
-
Sirtuins as regulators of metabolism and healthspan
-
1:CAS:528:DC%2BC38XjtlOktbw%3D 22395773
-
Houtkooper, R. H., Pirinen, E., & Auwerx, J. (2012). Sirtuins as regulators of metabolism and healthspan. Nat Rev Mol Cell Biol, 13, 225-238.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 225-238
-
-
Houtkooper, R.H.1
Pirinen, E.2
Auwerx, J.3
-
28
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
1:CAS:528:DC%2BD3sXntFCitr4%3D 12939617 10.1038/nature01960
-
Howitz, K. T., Bitterman, K. J., Cohen, H. Y., et al. (2003). Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature, 425, 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
-
29
-
-
77952547233
-
Ten years of NAD-dependent SIR2 family deacetylases: Implications for metabolic diseases
-
1:CAS:528:DC%2BC3cXlsFahsL8%3D 3526941 20226541 10.1016/j.tips.2010.02. 003
-
Imai, S., & Guarente, L. (2010). Ten years of NAD-dependent SIR2 family deacetylases: Implications for metabolic diseases. Trends Pharmacol Sci, 31, 212-220.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 212-220
-
-
Imai, S.1
Guarente, L.2
-
30
-
-
34548471739
-
Cytoplasm-localized SIRT1 enhances apoptosis
-
1:CAS:528:DC%2BD2sXhtVehtLvK 17516504 10.1002/jcp.21091
-
Jin, Q., Yan, T., Ge, X., et al. (2007). Cytoplasm-localized SIRT1 enhances apoptosis. J Cell Physiol, 213, 88-97.
-
(2007)
J Cell Physiol
, vol.213
, pp. 88-97
-
-
Jin, Q.1
Yan, T.2
Ge, X.3
-
31
-
-
64049092736
-
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease
-
1:CAS:528:DC%2BD1MXhsFGlsrg%3D 2813570 19104446 10.1097/NEN. 0b013e3181922348
-
Julien, C., Tremblay, C., Emond, V., et al. (2009). Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease. J Neuropathol Exp Neurol, 68, 48-58.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 48-58
-
-
Julien, C.1
Tremblay, C.2
Emond, V.3
-
32
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
1:CAS:528:DC%2BD2sXnsFejt7k%3D 1914106 17581637 10.1038/sj.emboj.7601758
-
Kim, D., Nguyen, M. D., Dobbin, M. M., et al. (2007). SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J, 26, 3169-3179.
-
(2007)
EMBO J
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
-
33
-
-
84873096554
-
Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: Neuroprotective or neurotoxic properties of Sirtuins in ALS?
-
22796962 10.1159/000338048
-
Körner, S., Böselt, S., Thau, N., et al. (2013). Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: Neuroprotective or neurotoxic properties of Sirtuins in ALS? Neurodegener Dis, 11, 141-152.
-
(2013)
Neurodegener Dis
, vol.11
, pp. 141-152
-
-
Körner, S.1
Böselt, S.2
Thau, N.3
-
34
-
-
0037312020
-
How does calorie restriction work?
-
1:CAS:528:DC%2BD3sXhtF2mtL4%3D 12569120 10.1101/gad.1052903
-
Koubova, J., & Guarente, L. (2003). How does calorie restriction work? Genes Dev, 17, 313-321.
-
(2003)
Genes Dev
, vol.17
, pp. 313-321
-
-
Koubova, J.1
Guarente, L.2
-
35
-
-
84876185003
-
Sirtuin1: A promising serum protein marker for early detection of Alzheimer's disease
-
10.1371/journal.pone.0061560
-
Kumar, R., Chaterjee, P., Sharma, P. K., et al. (2013). Sirtuin1: A promising serum protein marker for early detection of Alzheimer's disease. PLoS One. doi: 10.1371/journal.pone.0061560.
-
(2013)
PLoS One
-
-
Kumar, R.1
Chaterjee, P.2
Sharma, P.K.3
-
36
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
17936707 10.1016/j.molcel.2007.07.032
-
Li, X., Zhang, S., Blander, G., et al. (2007). SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell, 28, 91-106.
-
(2007)
Mol Cell
, vol.28
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
-
37
-
-
0035913911
-
Negative control of p53 by Sir2α promotes cell survival under stress
-
1:CAS:528:DC%2BD3MXotVSntro%3D 11672522 10.1016/S0092-8674(01)00524-4
-
Luo, J., Nikolaev, A. Y., Imai, S., et al. (2001). Negative control of p53 by Sir2α promotes cell survival under stress. Cell, 107, 137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
-
38
-
-
78149421022
-
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53
-
2958826 20975832 10.1371/journal.pone.0013502
-
Lynch, C. J., Shah, Z. H., Allison, S. J., et al. (2010). SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53. PLoS One, 5, e13502.
-
(2010)
PLoS One
, vol.5
, pp. 13502
-
-
Lynch, C.J.1
Shah, Z.H.2
Allison, S.J.3
-
39
-
-
32944479897
-
Assignment of the NAD-dependent deacetylase sirtuin 5 gene (SIRT5) to human chromosome band 6p23 by in situ hybridization
-
1:CAS:528:DC%2BD28XhsFSlsb4%3D 16484774 10.1159/000089872
-
Mahlknecht, U., Ho, A. D., Letzel, S., & Voelter-Mahlknecht, S. (2006). Assignment of the NAD-dependent deacetylase sirtuin 5 gene (SIRT5) to human chromosome band 6p23 by in situ hybridization. Cytogenet Genome Res, 112, 208-212.
-
(2006)
Cytogenet Genome Res
, vol.112
, pp. 208-212
-
-
Mahlknecht, U.1
Ho, A.D.2
Letzel, S.3
Voelter-Mahlknecht, S.4
-
40
-
-
78751700840
-
Distinct regulation of mitochondrial localization and stability of two human Sirt5 isoforms
-
1:CAS:528:DC%2BC3MXit1Oisrg%3D 21143562 10.1111/j.1365-2443.2010.01475.x
-
Matsushita, N., Yonashiro, R., Ogata, Y., et al. (2011). Distinct regulation of mitochondrial localization and stability of two human Sirt5 isoforms. Genes cells, 16, 190-202.
-
(2011)
Genes Cells
, vol.16
, pp. 190-202
-
-
Matsushita, N.1
Yonashiro, R.2
Ogata, Y.3
-
41
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
1:CAS:528:DC%2BD2MXhtVygtL%2FP 1237069 16079181 10.1091/mbc.E05-01-0033
-
Michishita, E., Park, J. Y., Burneskis, J. M., et al. (2005). Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell, 16, 4623-4635.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
-
42
-
-
77957001697
-
Acetylation of tau inhibits its degradation and contributes to tauopathy
-
1:CAS:528:DC%2BC3cXht1Wisr3K 3035103 20869593 10.1016/j.neuron.2010.08. 044
-
Min, S.-W., Cho, S.-H., Zhou, Y., et al. (2010). Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron, 67, 953-966.
-
(2010)
Neuron
, vol.67
, pp. 953-966
-
-
Min, S.-W.1
Cho, S.-H.2
Zhou, Y.3
-
43
-
-
0025908356
-
The consortium to establish a registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
-
1:STN:280:DyaK3M7oslajsQ%3D%3D 2011243 10.1212/WNL.41.4.479
-
Mirra, S. S., Heyman, A., McKeel, D., et al. (1991). The consortium to establish a registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology, 41, 479-486.
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Heyman, A.2
McKeel, D.3
-
44
-
-
84866350782
-
Metabolic syndrome, mild cognitive impairment and Alzheimer's disease-The emerging role of systemic low-grade inflammation and adiposity
-
1:CAS:528:DC%2BC38XhtlOnt7rO 22921944 10.1016/j.brainresbull.2012.08.003
-
Misiak, B., Leszek, J., & Kiejna, A. (2012). Metabolic syndrome, mild cognitive impairment and Alzheimer's disease-the emerging role of systemic low-grade inflammation and adiposity. Brain Res Bull, 89, 144-149.
-
(2012)
Brain Res Bull
, vol.89
, pp. 144-149
-
-
Misiak, B.1
Leszek, J.2
Kiejna, A.3
-
45
-
-
84857030932
-
National institute on Aging-Alzheimer's association guidelines for the neuropathologic assessment of Alzheimer's disease: A practical approach
-
1:CAS:528:DC%2BC38Xkt1eqtQ%3D%3D 3268003 22101365 10.1007/s00401-011- 0910-3
-
Montine, T. J., Phelps, C. H., Beach, T. G., et al. (2012). National institute on Aging-Alzheimer's association guidelines for the neuropathologic assessment of Alzheimer's disease: A practical approach. Acta Neuropathol, 123, 1-11.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 1-11
-
-
Montine, T.J.1
Phelps, C.H.2
Beach, T.G.3
-
46
-
-
11444256801
-
Glia and their cytokines in progression of neurodegeneration
-
1:CAS:528:DC%2BD2MXitVejtA%3D%3D 15639313 10.1016/j.neurobiolaging.2004. 05.010
-
Mrak, R., & Griffin, W. (2005). Glia and their cytokines in progression of neurodegeneration. Neurobiol Aging, 26, 349-354.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 349-354
-
-
Mrak, R.1
Griffin, W.2
-
47
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
1:CAS:528:DC%2BD38XotVKmtr0%3D 129731 12374852 10.1073/pnas.222538099
-
Onyango, P., Celic, I., McCaffery, J. M., et al. (2002). SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci USA, 99, 13653-13658.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
-
48
-
-
84857752986
-
75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes
-
1:CAS:528:DC%2BC38XivVGjtbs%3D 3269551 21987377 10.1002/art.33407
-
Oppenheimer, H., Gabay, O., Meir, H., et al. (2012). 75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes. Arthritis Rheum, 64, 718-728.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 718-728
-
-
Oppenheimer, H.1
Gabay, O.2
Meir, H.3
-
49
-
-
77957289008
-
Metabolic syndrome and cognitive impairment: Current epidemiology and possible underlying mechanisms
-
Panza, F., Frisardi, V., Capurso, C., et al. (2010). Metabolic syndrome and cognitive impairment: Current epidemiology and possible underlying mechanisms. J Alzheimer's Dis, 21, 691-724.
-
(2010)
J Alzheimer's Dis
, vol.21
, pp. 691-724
-
-
Panza, F.1
Frisardi, V.2
Capurso, C.3
-
50
-
-
84880791239
-
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
-
1:CAS:528:DC%2BC3sXhtVWlsLrI 23806337 10.1016/j.molcel.2013.06.001
-
Park, J. (2013). SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell, 50, 919-930.
-
(2013)
Mol Cell
, vol.50
, pp. 919-930
-
-
Park, J.1
-
51
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
Peng, C., Lu, Z., Xie, Z., et al. (2011). The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteom, 10(M111), 012658.
-
(2011)
Mol Cell Proteom
, vol.10
, Issue.M111
, pp. 012658
-
-
Peng, C.1
Lu, Z.2
Xie, Z.3
-
52
-
-
77950858637
-
Microglia in neurodegenerative disease
-
20234358 10.1038/nrneurol.2010.17
-
Perry, V. H., Nicoll, J. A. R., & Holmes, C. (2010). Microglia in neurodegenerative disease. Nat Rev Neurol, 6, 193-201.
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 193-201
-
-
Perry, V.H.1
Nicoll, J.A.R.2
Holmes, C.3
-
53
-
-
77955670715
-
The molecular genetics of sirtuins: Association with human longevity and age-related diseases
-
1:CAS:528:DC%2BC3cXptFagsLY%3D
-
Polito, L., Kehoe, P. G., Forloni, G., & Albani, D. (2010). The molecular genetics of sirtuins: Association with human longevity and age-related diseases. Int J Mol Epidemiol Genetics, 1, 214-225.
-
(2010)
Int J Mol Epidemiol Genetics
, vol.1
, pp. 214-225
-
-
Polito, L.1
Kehoe, P.G.2
Forloni, G.3
Albani, D.4
-
54
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
1:CAS:528:DC%2BD28XnsVOntLc%3D 16751189 10.1074/jbc.M602909200
-
Qin, W., Yang, T., Ho, L., et al. (2006). Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem, 281, 21745-21754.
-
(2006)
J Biol Chem
, vol.281
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
-
55
-
-
54049158932
-
Brain SIRT1: Anatomical distribution and regulation by energy availability
-
1:CAS:528:DC%2BD1cXht1ChsLjF 2578850 18829956 10.1523/JNEUROSCI.3257-08. 2008
-
Ramadori, G., Lee, C. E., Bookout, A. L., et al. (2008). Brain SIRT1: Anatomical distribution and regulation by energy availability. J Neurosci, 28, 9989-9996.
-
(2008)
J Neurosci
, vol.28
, pp. 9989-9996
-
-
Ramadori, G.1
Lee, C.E.2
Bookout, A.L.3
-
56
-
-
84862684427
-
Mitochondrial sirtuins-A new therapeutic target for repair and protection in multiple sclerosis
-
1:STN:280:DC%2BC38jis12isA%3D%3D 22708600 10.1111/j.1460-9568.2012.08150. x
-
Rice, C. M., Sun, M., Kemp, K., et al. (2012). Mitochondrial sirtuins-a new therapeutic target for repair and protection in multiple sclerosis. Eur J Neurosci, 35, 1887-1893.
-
(2012)
Eur J Neurosci
, vol.35
, pp. 1887-1893
-
-
Rice, C.M.1
Sun, M.2
Kemp, K.3
-
57
-
-
10744232772
-
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
-
1:CAS:528:DC%2BD3sXot12jsbk%3D 14580859 10.1016/S0531-5565(03)00209-2
-
Rose, G., Dato, S., Altomare, K., et al. (2003). Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp Gerontol, 38, 1065-1070.
-
(2003)
Exp Gerontol
, vol.38
, pp. 1065-1070
-
-
Rose, G.1
Dato, S.2
Altomare, K.3
-
58
-
-
0346094379
-
Predominant expression of Sir2α, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain
-
1:CAS:528:DC%2BD2cXovVWg 14706864 10.1016/S0014-5793(03)01444-3
-
Sakamoto, J., Miura, T., Shimamoto, K., & Horio, Y. (2004). Predominant expression of Sir2α, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett, 556, 281-286.
-
(2004)
FEBS Lett
, vol.556
, pp. 281-286
-
-
Sakamoto, J.1
Miura, T.2
Shimamoto, K.3
Horio, Y.4
-
59
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
1:CAS:528:DC%2BD38XmsVSntbk%3D 2174009 12186850 10.1083/jcb.200205057
-
Schwer, B., North, B. J., Frye, R. A., et al. (2002). The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol, 158, 647-657.
-
(2002)
J Cell Biol
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
-
60
-
-
77953724950
-
Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells
-
1:CAS:528:DC%2BC3cXntlaksb0%3D 20434449 10.1016/j.febslet.2010.04.063
-
Sugino, T., Maruyama, M., Tanno, M., et al. (2010). Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells. FEBS Lett, 584, 2821-2826.
-
(2010)
FEBS Lett
, vol.584
, pp. 2821-2826
-
-
Sugino, T.1
Maruyama, M.2
Tanno, M.3
-
61
-
-
34250365395
-
Nucleocytoplasmic shuttling of the NAD + -dependent histone deacetylase SIRT1
-
1:CAS:528:DC%2BD2sXitVCitLk%3D 17197703 10.1074/jbc.M609554200
-
Tanno, M., Sakamoto, J., Miura, T., et al. (2007). Nucleocytoplasmic shuttling of the NAD + -dependent histone deacetylase SIRT1. J Biol Chem, 282, 6823-6832.
-
(2007)
J Biol Chem
, vol.282
, pp. 6823-6832
-
-
Tanno, M.1
Sakamoto, J.2
Miura, T.3
-
62
-
-
0037172826
-
Phases of A-deposition in the human brain and its relevance for the development of AD
-
12084879 10.1212/WNL.58.12.1791
-
Thal, D. R., Rub, U., Orantes, M., & Braak, H. (2002). Phases of A-deposition in the human brain and its relevance for the development of AD. Neurology, 58, 1791-1800.
-
(2002)
Neurology
, vol.58
, pp. 1791-1800
-
-
Thal, D.R.1
Rub, U.2
Orantes, M.3
Braak, H.4
-
64
-
-
84856227226
-
Spatio-temporal expression analysis of the calcium-binding protein calumenin in the rodent brain
-
1:CAS:528:DC%2BC38XhsFGhurk%3D 3270221 22178608 10.1016/j.neuroscience. 2011.11.069
-
Vasiljevic, M., Heisler, F. F., Hausrat, T. J., et al. (2012). Spatio-temporal expression analysis of the calcium-binding protein calumenin in the rodent brain. Neuroscience, 202, 29-41.
-
(2012)
Neuroscience
, vol.202
, pp. 29-41
-
-
Vasiljevic, M.1
Heisler, F.F.2
Hausrat, T.J.3
-
65
-
-
0035913903
-
HSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
-
1:CAS:528:DC%2BD3MXotVSntrs%3D 11672523 10.1016/S0092-8674(01)00527-X
-
Vaziri, H., Dessain, S. K., Eaton, E. N., et al. (2001). hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase. Cell, 107, 149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
-
66
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
1:CAS:528:DC%2BD2cXmt1Gisb4%3D 15254550 10.1038/nature02789
-
Wood, J. G., Rogina, B., Lavu, S., et al. (2004). Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature, 430, 686-689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
-
67
-
-
78650516004
-
Identification of lysine succinylation as a new post-translational modification
-
1:CAS:528:DC%2BC3cXhsFGgtrfM 3065206 21151122 10.1038/nchembio.495
-
Zhang, Z., Tan, M., Xie, Z., et al. (2011). Identification of lysine succinylation as a new post-translational modification. Nat Chem Biol, 7, 58-63.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 58-63
-
-
Zhang, Z.1
Tan, M.2
Xie, Z.3
|