The ubiquitin-proteasome system in Creutzfeldt-Jakob and Alzheimer disease: Intracellular redistribution of components correlates with neuronal vulnerability

Neurobiology of Disease

Volumn 19, Issue 3, 2005, Pages 427-435

  Ádori, Csaba ^a   Kovács, Gábor G ^b,c   Low, Péter ^a   Molnár, Kinga ^a   Gorbea, Carlos ^d   Fellinger, Erzsébet ^a   Budka, Herbert ^c   Mayer, R John ^e   László, Lajos ^a  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^b NATIONAL INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Hungary)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Alzheimer; Apoptosis; Cell death; Hsp70; Neurodegeneration; Neuroprotection; Prion; Proteasome; Ubiquitin

Indexed keywords

ADENOSINE TRIPHOSPHATASE; HEAT SHOCK PROTEIN 72; PROTEASOME; PROTEIN ANTIBODY; PROTEIN SUBUNIT; UBIQUITIN;

ADULT; AGED; ALZHEIMER DISEASE; ANTIBODY LABELING; ARTICLE; CELL NUCLEUS; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CREUTZFELDT JAKOB DISEASE; CYTOPLASM; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MALE; NERVE CELL DEGENERATION; NEUROANATOMY; NEUROPATHOLOGY; NEUROPROTECTION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BLOTTING, WESTERN; BRAIN; CREUTZFELDT-JAKOB SYNDROME; FEMALE; HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MIDDLE AGED; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN;

EID: 22044446238     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.01.015     Document Type: Article

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