Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects

Free Radical Biology and Medicine

Volumn 72, Issue , 2014, Pages 285-295

  Tewari Singh, Neera ^a   Inturi, Swetha ^a   Jain, Anil K ^a   Agarwal, Chapla ^a   Orlicky, David J ^b   White, Carl W ^c   Agarwal, Rajesh ^a   Day, Brian J ^d  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c Children's Hospital Colorado   (United States)

^d DEPARTMENT OF MEDICINE   (United States)

Author keywords

Alkylating agents; Antioxidants; Chemical weapons; Free radicals; Medical countermeasure; Oxidative stress; Reactive oxygen species; Skin injury; Vesicating agents

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; AEOL 10150; ANTIOXIDANT; MUSTARD GAS; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 2-CHLOROETHYL ETHYL SULFIDE; ANTIDOTE; CHEMICAL WARFARE AGENT; METALLOPORPHYRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CATALYSIS; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; DRUG CYTOTOXICITY; DRUG TISSUE LEVEL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN INJURY; SKIN TOXICITY; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CELL SURVIVAL; COMET ASSAY; DRUG EFFECTS; HAIRLESS MOUSE; PATHOLOGY; SKIN; TOXICITY;

ANIMALS; ANTIDOTES; ANTIOXIDANTS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL WARFARE AGENTS; COMET ASSAY; HUMANS; METALLOPORPHYRINS; MICE; MICE, HAIRLESS; MUSTARD GAS; OXIDATIVE STRESS; SKIN;

EID: 84901330845     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.04.022     Document Type: Article

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