Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts

Free Radical Biology and Medicine

Volumn 51, Issue 12, 2011, Pages 2272-2280

  Inturi, Swetha ^a   Tewari Singh, Neera ^a   Gu, Mallikarjuna ^a   Shrotriya, Sangeeta ^a   Gomez, Joe ^a   Agarwal, Chapla ^a   White, Carl W ^b   Agarwal, Rajesh ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

Author keywords

8 OHdG; CEES; DNA damage; Free radicals; H2A.X; Oxidative stress; p53

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DNA; ETHYL 2 CHLOROETHYL SULFIDE; GLUTATHIONE; HISTONE H2AX; MUSTARD GAS DERIVATIVE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TYPE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; EPIDERMIS CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SKIN FIBROBLAST;

ANIMALS; CELL LINE; CHROMANS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GLUTATHIONE; HISTONES; MICE; MICE, HAIRLESS; MUSTARD GAS; OXIDATION-REDUCTION; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SKIN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 81855178199     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.08.020     Document Type: Article

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